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Chinese Journal of Polymer Science 2021年第6期39卷 692-701,I0005页

作者： Xiang zhang Da-Wei jiang Guo-Liang Yang Yu-Cheng Zhu jia Tian Hong-Liang Cao Yun Gao Wei-An zhang Shanghai Key Laboratory of Functional Materials Chemistry East China University of Science and TechnologyShanghai 200237China

Phototherapies including photodynamic therapy(PDT)and photothermal therapy(PTT)are the most promising and non-invasive cancer ***,the efficacy of mono-therapy of PDT or PTT is often limited by the phototherapeutic defects such as low light penetration depth of photosensitizers and insufficiency of photothermal ***(ONOO−)has been proved to be an efficient oxidizing and nitrating agent that involves in various physiological and pathological ***,ONOO−produced in tumor site could be an effective treatment in cancer ***,a novel cyanine dye-based(Cy7)polymer nanoplatform is developed for enhanced phototherapy by in situ producing ONOO−.The Cy7 units in the nanoparticles can not only be served as the photosensitizer to produce reactive oxygen species(ROS)including singlet oxygen and superoxide anion for PDT,but also be used as a heat source for PTT and the release of NO gas from N-nitrosated napthalimide(NORM)at the same *** NO can react quickly with superoxide anion to generate ONOO−,the enhanced phototherapy could be achieved by in situ ONOO−produced by PCy7-NO upon exposure to the near infrared(NIR)***,the NIR-triggered Cy7-based nanoplatform for ONOO−-enhanced phototherapy may provide a new perspective in cancer therapy.

关键词： Peroxynitrite(ONOO^(-)) Phototherapy Cyanine Napthalimide Near-infrared

Accurate construction of cell membrane biomimetic graphene nanodecoys via purposeful surface engineering to improve screening efficiency of active components of traditional Chinese medicine

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Acta Pharmaceutica Sinica B 2022年第1期12卷 394-405页

作者： Qi Hu Lanlan jia Xiaolin zhang Aihong Zhu Sicen Wang Xiaoyu Xie School of Pharmacy Health Science CenterXi’an Jiaotong UniversityXi'an 710061China Shaanxi Engineering Research Center of Cardiovascular Drugs Screening&Analysis Xi'an 710061China

Biomimetic nanoengineering presents great potential in biomedical research by integrating cell membrane(CM) with functional nanoparticles. However, preparation of CM biomimetic nanomaterials for custom applications that can avoid the aggregation of nanocarriers while maintaining the biological activity of CM remains a challenge. Herein, a high-performance CM biomimetic graphene nanodecoy was fabricated via purposeful surface engineering, where polyethylene glycol(PEG) was used to modifying magnetic graphene oxide(MGO) to improve its stability in physiological solution, so as to improve the screening efficiency to active components of traditional Chinese medicine(TCM). With this strategy, the constructed PEGylated MGO(PMGO) could keep stable at least 10 days, thus improving the CM coating efficiency. Meanwhile, by taking advantage of the inherent ability of He La cell membrane(HM) to interact with specific ligands, HM-camouflaged PMGO showed satisfied adsorption capacity(116.2 mg/g) and selectivity. Finally, three potential active components, byakangelicol, imperatorin,and isoimperatorin, were screened from Angelica dahurica, whose potential antiproliferative activity were further validated by pharmacological studies. These results demonstrated that the purposeful surfaceengineering is a promising strategy for the design of efficient CM biomimetic nanomaterials, which will promote the development of active components screening in TCM.

关键词： Cell membrane Biomimetic nanoengineering Purposeful surface engineering Graphene oxide Dispersity Active components screening Traditional Chinese medicine PEGylation

THREE-DIMENSIONAL NUMERICAL MODEL FOR WINDING TIDAL RIVER WITH BRANCHES

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Journal of Hydrodynamics 2007年第2期19卷 249-254页

作者： YANG Li-ling WANG Yun-hong ZHU Zhi-xia xu veng-jun DENG jia-quan YANG Fang School of Naval Architecture Ocean and Civil Engineering Shanghai Jiaotong University Shanghai 200030 China Pearl River Hydraulic Research Institute Guangzhou 510610 China

Natural rivers are usually winding with branches and shoals, which are difficult to be simulated with rectangular grids. A 3-D current numerical model was established based on the orthogonal curvilinear coordinate system and vertical o coordinate system. The equations were discretisized using a semi-implicit scheme. The ＂predictor＂ and ＂corrector＂ steps were applied for the horizontal momentum equations to meet the basic requirement that the depth-integrated currents obtained from the equations for 2-D and 3-D modes have identical values. And a modification of traditional method of dry/wet discriminance was proposed to determine accurately the boundary and ensure the continuity of variable boundary in the simulation. This model was verified with the data measured in a winding tidal river with branches in April, 2004. The simulated data of water levels and velocities agree well with the measured ones, and the computed results reveal well the practical flow characteristics, including the vertical secondary flow in a winding reach.

关键词： winding tidal river 3-D numerical model,semi-implicit scheme variable boundary

Experimental test of robustness of composite pulses to non-static classic noise in NMR

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Science China(Physics,Mechanics & Astronomy) 2017年第2期60卷 80-81页

作者： LI xueChen zhang PanPan CHU JingDi LI JiYuan jia PengYing Key Lab of Photo-Electronics Information Materials of Hebei Provinc

High fidelity and robust quantum control is the requirement for Quantum Information Processing （QIP） and quantum cornputing applications. Many negative factors, like pulse length error, system-bath coupling and the fluctuation of electronic instruments, deviate the quantum system evolution from the ideal path. To suppress these errors, many quantum manipulation techniques have been proposed. Composite pulses are designed to suppress off resonance error, pulse length error or the combination of them.

关键词：噪声鲁棒性脉冲核磁共振复合量子信息处理实验静态长度误差

Amperometric Biosensor for Detection of Phenolic Compounds Based on Tyrosinase, N-AcetyI-L-cysteinecapped Gold Nanoparticles and Chitosan Nanocomposite

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Chinese Journal of Chemistry 2017年第8期35卷 1305-1310页

作者： Wenjuan Dong Jiyan Han jia Shi Wenting Liang Yuexia zhang Chuan Dong Institution of Environmental Science College of Chemistry and Chemical Engineering Shanxi University Taiyuan Shanxi 030006 China Department of Laboratory Medicine College of Fenyang Shanxi Medical University Fenyang Shanxi 032200 China

A novel biosensor was fabricated based on the immobilization of tyrosinase and N-acetyl-L-cysteine-capped gold nanoparticles onto the surface of the glassy carbon electrode via the film forming by chitosan. The NAC-AuNPs （N-acetyl-L-cysteine-capped gold nanoparticles） with the average size of 3.4 nm had much higher specific surface area and good biocompatibility, which were favorable for increasing the immobilization amount of enzyme, retaining the catalytic activity of enzyme and facilitating the fast electron transfer. The prepared biosensor exhibited suitable amperometric responses at -0.2 V for phenolic compounds vs. saturated calomel electrode. The parameters of influencing on the working electrode such as pH, temperature, working potential were investigated. Under optimum conditions, the biosensor was applied to detect catechol with a linear range of 1.0 ×10^-7 to 6.0 × 10^-5 mol·L^-1 , and the detection limit of 5.0×10^-8mol·L^-1 （S/N=3）. The stability and selectivity of the proposed biosensor were also evaluated.

关键词： tyrosinase biosensor gold nanoparticles phenolic compounds

Hormonal Regulation of Leaf Morphogenesis in Arabidopsis

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Journal of Integrative Plant Biology 2007年第1期49卷 75-80页

作者： Lin-Chuan Li Ding-Ming Kang zhang-Liang Chen Li-jia Qu National Laboratory for Protein Engineering and Plant Genetic Engineering Peking-Yale Joint Research Center for Plant Molecular Genetics and AgroBiotechnology College of Life Sciences Peking University Beijing 100871 China Key Laboratory of Crop Genomics and Genetic Improvement of Ministry of Agriculture/Key laboratory of Crop Genetic Improvement of Beijing City College of Agronomy and Biotechnology China Agricultural University Beijing 100094 China

Leaf morphogenesis is strictly controlled not only by intrinsic genetic factors, such as transcriptional factors, but also by environmental cues, such as light, water and pathogens. Nevertheless, the molecular mechanism of how leaf morphogenesis is regulated by genetic programs and environmental cues is far from clear. Numerous series of events demonstrate that plant hormones, mostly small and simple molecules, play crucial roles in plant growth and development, and in responses of plants to environmental cues such as light. With more and more genetics and molecular evidence obtained from the model plant Arabidopsis, several fundamental aspects of leaf morphogenesis including the initiation of leaf primordia, the determination of leaf axes, the regulation of cell division and expansion in leaves have been gradually unveiled. Among these phytohormones, auxin is found to be essential in the regulation of leaf morphogenesis.

关键词： auxin curly leaf hormonal regulation leaf morphogenesis leaf shape

Optical Absorption Spectra of Cr^(3+) and Cr^(4+) in Sr_(3)Ga_(2)Ge_(4)O_(14) Garnet Crystals

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Chinese Physics Letters 1995年第7期12卷 424-427页

作者： xu Jun DENG Peizhen zhang Qiang GAN Fuxi Shanghai Institute of Optics and Fine Mechanics Academia SinicaShanghai 201800

Single crystals of Sr_(3)Ga_(2)Ge_(4)O_(14):Cr are grown by the Czochralski *** polarized optical absorption spectra of Cr in visible and near-infrared wavelength are presented and *** is suggested that Cr enters the ... 详细信息

关键词： method visible

Design and testing of the mechanical picking function of a high-speed seedling auto-transplanter

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Artificial Intelligence in Agriculture 2021年第1期5卷 64-71页

作者： Changjie Han Xianwei Hu Jing zhang jia You Honglei Li College of Mechanical and Electrical Engineering Xinjiang Agricultural UniversityUrumqi 830052China College of Mechanical and Electronic Engineering Xinjiang Vocational UniversityUrumqi 830013China Jinlida Machinery Manufacturing Co. Ltd.Dezhou 253400China

To improve the low transplanting efficiencies and simplify the complex structures of current automatic transplanters,a mechanical high-speed transplanter for picking plug seedlings that is suitable for planting on plastic filmswas *** components were an automatic seedling picking systemand a basket-type planting system,whichwere used for the following processes:automatic picking,planting,soil covering,and suppression of plug *** performance test was performed on the automatic transplanter with 60-day-old pepper *** transplanting efficiency was tested at speeds of 40,60,90,and 120 plants·min−*** results showed that the coefficient of variation(CV)of the plant spacing and the missed transplanting rate increased with the planting frequency,whereas the qualified rate of planting perpendicularity and the qualified rate of planting decreasedwith the increase in the planting *** planting indicesmet the JB/T 102912013 *** results of this study showed that the auto-transplanter could performhigh-speed transplanting on the basis of completing the following functions:automatic picking,planting,soil covering,and suppression of plug seedlings.

关键词： Automatic transplanter Plug seedling Planting on films Planting Index

Construction of metal chalcogenolate cluster linked organic frameworks

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Chinese Journal of Structural Chemistry 2023年第8期42卷 4-7页

作者： Zhongqi Wu Qian-Feng zhang Chao xu Institute of Molecular Engineering and Applied Chemistry Anhui University of TechnologyMa'anshan243002PR China Division of Nanotechnology and Functional Materials Department of Materials Science and EngineeringÅngström LaboratoryUppsala UniversityUppsala75121Sweden

Metal chalcogenide/chalcogenolate clusters(MCCs)are nanoclusters composed of metal and chalcogen ligands,typically containing several to hundreds of metal and chalcogen atoms[1-4].Within these structures,chalcogen ligands(RE^(-)or E^(2-),where R=organic group and E=S,Se,Te)can adopt a variety of bridging coordination modes that connect metal centers into nanoscale *** typically have a well-defined crystal structure,allowing for the study of the structure-properties relationships at the atomic and molecular ***,they usually exhibit unique physicochemical properties that differ from their bulk *** example,the electronic structure and optical properties of MCCs can be precisely tuned by controlling their molecular size,core structure,peripheral organic ligands,and spatial arrangement[5-8].As a result,MCCs are promising materials for applications in energy conversion,sensing,luminescence,and photocatalysis[9-12].

关键词： typically structure cluster

Calcified roasting-acid leaching process of vanadium from low-grade vanadium-containing stone coal

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Chinese Journal Of Geochemistry 2014年第2期33卷 163-167页

作者： WANG Taiying xu Longjun LIU Chenlun zhang Zhaodi State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing University College of Chemistry and Chemical Engineering Chongqing University

The low-grade vanadium-containing stone coal used in this experiment was collected from Wuxi Country, Chongqing City, China. The experiment focused on the vanadium recovery from roasted residue through optimizing the process conditions of an effective and environmentally-friendly technology, named calcified roasting-sulfuric acid leaching technology. By single-factor experiments and orthogonal experiments, the effects of roasting temperature, roasting time, sulfuric acid concentration and leaching time on the leaching ratio of vanadium were analyzed. The results showed that the leaching ratio of vanadium reached 85.5% under the proper technological conditions of roasting temperature=950℃, roasting time=4 h, 40% concentration of sulfuric acid and leaching time=6 h.

关键词：含钒石煤钙化焙烧酸浸工艺低品位硫酸浓度正交实验焙烧时间浸出时间