检索结果-南通市图书馆

Journal of Thermal Science 2021年第5期30卷 1572-1580页

作者： WAng Xuehui YAN Yuying WRIGHT Edward HAO xinyue GAO Neng Fluids and Thermal Engineering Research Group Faculty of EngineeringUniversity of NottinghamNottinghamNG72RDUK Ningbo Institute of Technology Zhejiang UniversityNingbo315100China Research Centre for Fluids and Thermal Engineering University of Nottingham Ningbo ChinaNingbo315100China

In this paper,the entrainment ratio,pump work,heat loads of heat exchangers and COPthermal were theoretically evaluated for a solar-driven ejector-vapor compression hybrid refrigeration system with R1233zd(E)and R1336mzz(Z)as the working *** evaluation of the utilization potentials of R1233zd(E)and R1336mzz(Z)was presented by comparing the system performance with that of R245fa,a commonly used refrigerant in the ejector *** results indicated that the systems with R1233zd(E)and R1336mzz(Z)had a higher entrainment ratio and lower pump *** pump works when using R1233zd(E)and R1336mzz(Z)can be up to 14.59%and 38.05%lower than those of R245fa,***,the system showed the highest COPthermal utilizing R1233zd(E)followed by that of R245fa,with the R1336mzz(Z)system having the lowest *** differences between R1233zd(E)and R1336mzz(Z)systems,R1233zd(E)and R245fa systems were 4.33%and 2.0%,*** paper was expected to provide a good reference for the utilizing prospect of R1233zd(E)and R1336mzz(Z)in ejector refrigeration systems.

关键词： low GWP alternative refrigerants ejector R1233zd(E) R1336mzz(Z)

Experimental Investigation of the Ejector Refrigeration Cycle for Cascade System Application

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2022年第5期31卷 1476-1486页

作者： HAO xinyue GAO Neng CHEN Guangming VOLOVYK Oleksii WAng Xuehui XUAN Yongmei Institute of Refrigeration and Cryogenics Zhejiang UniversityHangzhou310027China Ningbo Institute of Technology Zhejiang UniversityNingbo315100China Fluids and Thermal Engineering Research Group Faculty of EngineeringUniversity of NottinghamNottinghamNG72RDUK

Ejector refrigeration cycle(ERC)with advantages of simple structure and low cost holds great application potential in cascade/hybrid cycles to improve the overall system performance by removing or recovering the heat from the main *** this paper,a theoretical and experimental investigation of the ERC as a part of a cascade system was carried *** operating parameters were *** experimental ERC test rig was designed,developed and investigated at high evaporating temperatures and wide ranges of operating *** influence of operating conditions on the efficiency of the ejector and ERC was *** results and analysis in this study can be helpful for the application and operating condition optimization of ERC in cascade/hybrid refrigeration systems.

关键词： ejector ejector refrigeration cycle cascade refrigeration system experiment performance

Peripheral blood indices to predict PFS/OS with anlotinib as a subsequent treatment in advanced small-cell lung cancer

在线全文

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2022年第8期19卷 1249-1258页

作者： Cuicui zh.ng Jing Wang xinyue Wang zhaoting Meng Ying Cheng Kai Li Department of Thoracic Oncology Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin’s Clinical Research Center for CancerTianjin 300060China Jilin Cancer Hospital Changchun 130021China

Objective:In the phase II ALTER-1202(NCT03059797)trial,anlotinib significantly improved progression-free survival(PFS)and overall survival(OS)in patients with advanced small-cell lung cancer(SCLC)who underwent at least 2 previous chemotherapy cycles,when compared with a placebo *** identify potential factors for predicting efficacy and prognosis with anlotinib treatment,we analyzed hematological indices at baseline and adverse events(AEs)over the course of anlotinib ***:Data were collected from March 2017 to April 2019 from a randomized,double-blind,placebo-controlled,multicenter,phase II trial of *** patients were randomly assigned 2:1 to receive anlotinib or placebo until disease progression,intolerable toxicity,or withdrawal of *** patients received anlotinib(12 mg)or an analogue capsule(placebo)orally once daily for 14 days every 3 *** hematological indices at baseline and AEs that occurred in the initial 2 treatment cycles were *** Kaplan-Meier test and Cox regression model were used to assess survival ***:A total of 82 patients(81 patients with complete data)were randomly assigned to receive anlotinib,with 38 receiving a placebo as a *** analysis indicated that an elevated neutrophil to lymphocyte ratio>7.75 and lactate dehydrogenase>254.65 U/L at baseline were independent risk factors for PFS;basal elevated aspartate aminotransferase>26.75 U/L,neuron specific enolase>18.64 ng/mL,and fibrinogen>4.645 g/L were independent risk factors for *** treatment,elevatedγglutamyltransferase and hypophosphatemia were independent predictors for a poor PFS,and elevatedγ-glutamyl transferase and hypercholesterolemia were independent factors for ***:Our study preliminarily defined potential factors that affected the PFS and OS at baseline and during anlotinib treatment in patients with advanced *** findings provide a basis for screening the dominant population and f

关键词： Small-cell lung cancer anlotinib predictive factors PFS OS

Investigating the Z'gauge boson at future lepton colliders

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2022年第5期46卷 52-59页

作者： xinyue Yin Honglei Li Yi Jin zhilong Han Zongyang Lu School of Physics and Technology University of JinanJinan 250022China Guangxi Key Laboratory of Nuclear Physics and Nuclear Technology Guangxi Normal UniversityGuangxi 541004China

Z′boson as a new gauge boson has been proposed in many new physics *** interactions of Z′coupling to fermions have been studied in detail at the large hadron collider.A Z′with the mass of a few TeV has been excluded in some special *** lepton colliders will focus on the studies of Higgs physics,which provide the advantage to investigate the interactions of the Higgs boson with the new gauge *** investigate the Z′zh interaction via the process of e^(+)e^(-)→Z′/Z→zh→l^(+)l^(−)bb¯.The angular distribution of the final leptons decaying from the Z-boson is related to the mixing of Z′-Z and the mass of Z′.The forward-backward asymmetry is proposed as an observable to investigate Z′-Z *** angular distributions change significantly with some special beam polarization compared with the unpolarized condition.

关键词： Z',new physics lepton collider

黄萎病菌诱导下陆地棉酵母双杂交文库的构建及GhMAPKKK2互作蛋白的筛选

在线全文

学校读者我要写书评

暂无评论

核农学报 2025年第1期39卷 68-76页

作者：程贯富张文祥郭新悦张国帅吕晓迪代培红雷建峰李月新疆农业大学生命科学学院新疆乌鲁木齐830052 新疆农业大学农学院新疆乌鲁木齐830052

为了探究棉花响应黄萎病菌侵染的分子机制并筛选GhMAPKKK2的互作蛋白,以陆地棉XLZ35为材料,基于Gateway克隆技术构建了棉花黄萎病菌诱导的陆地棉酵母双杂交文库,其中初级文库和次级文库的库容分别为1.2×10^(7)和2.0×10^(7)CFU,插入片... 详细信息

为了探究棉花响应黄萎病菌侵染的分子机制并筛选GhMAPKKK2的互作蛋白,以陆地棉XLZ35为材料,基于Gateway克隆技术构建了棉花黄萎病菌诱导的陆地棉酵母双杂交文库,其中初级文库和次级文库的库容分别为1.2×10^(7)和2.0×10^(7)CFU,插入片段重组率均为100%且平均长度大于1000 bp。次级文库质粒浓度为953 ng·μL^(-1),符合构建酵母文库的标准,可用于酵母双杂交筛选互作蛋白。构建了pGBKT7-GhMAPKKK2表达载体,并验证了该载体对酵母细胞无毒性且不存在自激活活性。以GhMAPKKK2为诱饵蛋白,利用酵母文库初步筛选,获得81个阳性互作蛋白,经测序对比选取6个候选蛋白,通过酵母双杂交及双分子荧光互补试验(BiFC)验证,明确了候选蛋白GhFLA与GhMAPKKK2存在互作关系。本研究结果为解析GhMAPKKK2调控棉花抗黄萎病反应分子机制及调控网络提供了重要参考。

关键词：棉花黄萎病菌酵母双杂交互作蛋白 GhMAPKKK2

维普期刊数据库博看期刊

The Fluorescence Immunochromatographic Strips for Natamycin and Its Application in Food Safety Detection

在线全文

学校读者我要写书评

暂无评论

Agricultural Biotechnology 2019年第6期8卷 104-105页

作者： Wei zh.ng Yongfeng LIU Yafei XU zhijun QIU xinyue LI Beilun Customs Ningbo 315000China zhenhai District Agricultural Technology Extension Station Ningbo 315000China

A fluorescence immunochromatographic strip was developed in this study for natamycin detection in food. The results showed that the best amount of labeled antibody was 10 μg, for every 50 μl of fluorescent microspheres with a 2.5%(w/v) concentration. This labeled antibody was diluted for 10 times, and the diluted solution was dispensed into conjugate pad at the amount of 3 μl/cm. The concentrations of natamycin labeled BSA for test line and goat anti-mouse IgG for control line were 2.0 and 1 mg/ml, respectively, which performed best. With the best conditions, the limit of detection was 1 ng/ml, the linearity ranged from 2 to 100 ng/ml, the recovery was about 80% to 120%, and the CV was below 23%.

关键词： Food safety detection Natamycin Fluorescence immunochromatographic assay

从加入到脱离:一项不同年龄群体参与社群活动的扎根研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

宜宾学院学报 2021年第2期21卷 17-27页

作者： Jhony Choon Yeong ng 陈心悦李敏吴沐旋南京航空航天大学经济与管理学院江苏南京211106 江苏师范大学文学院江苏徐州221116

采用扎根理论的方法,针对个体社群参与互动的过程,访谈了中学生、大学生、在职人士和离退休人士四个不同年龄群体发现:个体从选择加入社群、参与社群活动以及最后离开社群的整个过程中,社群参与动机是个体参与社群的起因;社群活动影响... 详细信息

采用扎根理论的方法,针对个体社群参与互动的过程,访谈了中学生、大学生、在职人士和离退休人士四个不同年龄群体发现:个体从选择加入社群、参与社群活动以及最后离开社群的整个过程中,社群参与动机是个体参与社群的起因;社群活动影响个体感知,从而影响不同社群的参与经历;过去的社群参与经历会影响未来社群参与的动机及选择。社群管理者应营造温暖的氛围,合理分配工作;而社群成员应调整心态,主动解决问题,积极应对社群参与中的各种情况,让社群和谐发展。

关键词：社群参与社群选择社群活动扎根理论

基于金属有机框架的荧光适配体传感器检测红酒中黄曲霉毒素B_(1)

在线全文

学校读者我要写书评

暂无评论

现代食品科技 2023年第6期39卷 306-312页

作者：姚惠文王馨悦雷欣莹湖北中医药大学药学院湖北武汉430065

该文利用金属有机框架(Metal-organicFramework,MOF)材料和荧光标记的核酸适配体构建一种基于光诱导电子转移的荧光适配体传感器用于黄曲霉毒素B_(1)(AflatoxinB_(1),AFB_(1))的检测。MOF材料为氨基功能化的奥斯陆大学66(Amino-function... 详细信息

该文利用金属有机框架(Metal-organicFramework,MOF)材料和荧光标记的核酸适配体构建一种基于光诱导电子转移的荧光适配体传感器用于黄曲霉毒素B_(1)(AflatoxinB_(1),AFB_(1))的检测。MOF材料为氨基功能化的奥斯陆大学66(Amino-functionalized University of Oslo66,UiO-66-NH_(2)),标记有四甲基罗丹明(Tetramethylrhodamine,TAMRA)荧光团的核酸适配体(TAMRA-aptamer)通过π-π堆积作用吸附于UiO-66-NH_(2)表面,由于光诱导电子转移使TAMRA-aptamer的荧光猝灭。加入目标物AFB_(1)后,核酸适配体与AFB_(1)特异性识别并结合,使核酸适配体从单链结构转变为稳定的内环结构。由于内环结构与UiO-66-NH_(2)之间的结合能力较弱,光诱导电子转移被阻断,TAMRA-aptamer荧光恢复。该荧光适配体传感器用于AFB_(1)检测,在1.00~100.00 ng/mL范围内荧光信号强度与AFB_(1)浓度具有良好的线性相关性,相关系数的平方(R^(2))为0.994,检测限为0.50ng/mL。该方法用于红酒中AFB_(1)的测定,样品添加回收率为90.00%~101.00%。该方法操作简便、成本低、选择性好、灵敏度高,可用于红酒中AFB_(1)的快速检测。

关键词：黄曲霉毒素B_(1) 金属有机框架核酸适配体荧光传感器

紫外线照射对两种纳米形貌钛种植体表面巨噬细胞生物学行为及炎症细胞因子分泌的影响

在线全文

学校读者我要写书评

暂无评论

中华口腔医学杂志 2019年第3期54卷 183-187页

作者：吕武龙邓炜刘大勇运新跃李长义天津医科大学口腔医院口腔综合科 300070 赣南医学院第一附属医院口腔科赣州341000 天津医科大学口腔医院牙体牙髓科 300070

目的研究紫外线照射对两种纳米形貌钛种植体表面巨噬细胞生物学行为及炎症细胞因子分泌的影响,为紫外线照射在种植体改性方面的临床应用提供依据。方法钛试件经氢氟酸酸蚀或氢氟酸酸蚀+阳极氧化分别制备酸蚀组和氧化组钛试件各27个,场... 详细信息

目的研究紫外线照射对两种纳米形貌钛种植体表面巨噬细胞生物学行为及炎症细胞因子分泌的影响,为紫外线照射在种植体改性方面的临床应用提供依据。方法钛试件经氢氟酸酸蚀或氢氟酸酸蚀+阳极氧化分别制备酸蚀组和氧化组钛试件各27个,场发射扫描电镜观察两组各1个试件的表面形貌。试件避光保存8周后,两组各取13个试件用紫外线照射48 h(即酸蚀+紫外线组和氧化+紫外线组),以未经紫外线照射的酸蚀组和氧化组钛试件作为对照。检测各组钛试件表面接触角;各组钛试件与小鼠巨噬细胞共培养4、24和72 h后,检测各组细胞黏附和增殖情况,扫描电镜观察细胞形态;液相芯片技术检测培养24和72 h时细胞上清液中肿瘤坏死因子α(tumor necrosis factor α,TNF-α)、单核细胞趋化蛋白1(monocyte chemotactic protein-1,MCP-1)和巨噬细胞炎症蛋白1α(macrophage inflammatory protein-1α,MIP-1α)的质量浓度。结果酸蚀组钛试件表面可见微米凹坑和纳米柱,氧化组钛试件表面可见微米凹坑和TiO2纳米管结构。酸蚀+紫外线组和氧化+紫外线组表面接触角(分别为20.2°±2.8°和0.0°±0.0°)均显著小于酸蚀组和氧化组(P0.05),培养72 h时酸蚀+紫外线组和氧化+紫外线组细胞增殖[A值分别为(0.92±0.13)和(1.10±0.08)]均分别显著大于酸蚀组和氧化组(Png/L]、MCP-1质量浓度[分别为(301.7±50.3)和(240.8±18.7)ng/L]、MIP-1α质量浓度[分别为(224.9±30.6)和(233.9±14.9)ng/L]均分别显著小于酸蚀组和氧化组(P<0.05)。结论紫外线照射能增加两种纳米形貌钛试件亲水性,尤其是氧化+紫外线组。紫外线照射可促进两种纳米形貌钛表面巨噬细胞增殖、减轻炎症反应。

关键词：钛紫外线巨噬细胞巨噬细胞炎性蛋白质类纳米管

东部近海海产品中有机磷和敌草隆农药的残留特征与健康风险评估

在线全文

学校读者我要写书评

暂无评论

环境科学研究 2024年第9期37卷 2054-2063页

作者：解满俊董欣悦李梦娜尹杰李娟英上海海滨污水处理有限公司上海201302 上海海洋大学海洋科学与生态环境学院上海201306 上海河湖生物链构建与资源化利用工程技术研究中心上海201702

为深入了解我国东部近海海产品中有机磷农药(OPPs)和敌草隆农药的残留特征和健康风险,对来自中国东部近海海域的典型海产品进行了抽样调查,采用气相色谱-三重四级杆串联质谱仪(GC-MS/MS)和高效液相色谱-三重四级杆串联质谱仪(LC-MS/MS)... 详细信息

为深入了解我国东部近海海产品中有机磷农药(OPPs)和敌草隆农药的残留特征和健康风险,对来自中国东部近海海域的典型海产品进行了抽样调查,采用气相色谱-三重四级杆串联质谱仪(GC-MS/MS)和高效液相色谱-三重四级杆串联质谱仪(LC-MS/MS)对海产品体内OPPs和敌草隆含量进行测定和分析。结果表明:①8种OPPs总残留浓度为47~6638 ng/g(以干质量计),平均值为707 ng/g;敌草隆浓度范围为nd(未检出)~3.3 ng/g,平均值为0.49 ng/g。与甲壳类和鱼类相比,OPPs和敌草隆更易蓄积在以滤食底层悬浮物为食的软体动物体内。②空间分布上,OPPs在不同采样点海产品体内的残留浓度差异显著,敌草隆在舟山海域海产品体内残留浓度相对较高。③除连云港市海域软体动物缢蛏总风险指数(HI)值为1.1外,其余海产品中9种农药残留产生的HI值均小于1,健康风险相对较低,处于可接受水平。三唑磷和喹硫磷在螠蛏和大黄鱼的体内残留量相对较高,应进一步重点关注。研究显示,东部近海海产品中,儿童摄入软体动物类的风险尤为突出。因此,建议东部沿海居民,特别是儿童群体,应控制高风险海产品的摄入量以保障健康安全。

关键词：有机磷农药敌草隆农药海产品健康风险评估