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Stroke (Cerebrovascular Accident): Epidemiological, Clinical and Evolving Aspects in the Internal Medicine Department of the Public Health Establishment 1 (EPS1) of Tivaouane

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Open Journal of Internal Medicine 2023年第4期13卷 313-329页

作者： Fulgence Abdou Faye Bachir Mansour Diallo Awa Ba Amina Dia Guèye Abdou Khadre Mbaye zeinabou marone Adama Berthé Papa Soulèyemane Touré Madoky Magatte Diop Bernard Marcel Diop Mamadou Mourtalla Ka UFR of Health Sciences Alioune Diop University of Bambey Bambey Senegal Department of Internal Medicine Regional Hospital Heinrich Lucké of Diourbel Diourbel Senegal Department of Internal Medicine Abdou Aziz Sy Dabakh Hospital Tivaouane Senegal Internal Medicine Department Regional Hospital of Thiès Thiès Senegal UFR of Health Sciences Iba Der Thiam University of Thiès Thiès Senegal

Introduction: The frequency, severity, cost of treatment, morbidity and mortality of stroke make it a real public health problem. In industrialized countries, strokes are the leading cause of physical disability in adults, the second leading cause of dementia (after Alzheimer’s disease), and the third leading cause of death (after cancer and cardiovascular disease). It’s also a major cause of depression. The objective of our study was to describe the epidemiological, clinical and evolutionary aspects of stroke in the internal medicine department of Tivaouane Hospital. Material and Method: This is a retrospective study carried out from January 1, 2015 to December 31, 2018 on the files of patients hospitalized for stroke in the medical department of the EPS1 in Tivaouane. We took into account all the patients who had a brain CT (computed tomography) scan. We collected data related to socio-demographic characteristics, history, risk factors, reasons for admission, clinical signs, paraclinical examinations, as well as evolution. Results: Out of 1999 patients, 206 files of patients with stroke were collected, i.e. a proportion of 10.3%. Our study population had a mean age of 65.53 years [16 - 97 years]. We noted a clear predominance of women (50.5%). The majority of the population came from the outskirts of Tivaouane (56.7%). Risk factors for stroke were dominated by hypertension (90.3%), dyslipidemia (19.4%), previous stroke (18.9%), and diabetes (16%). The clinical signs were dominated by a motor deficit (94.1%), speech disorders (67.4%) and consciousness disorders (47%). Ischemic strokes were predominant (65%) over hemorrhagic strokes (34.5%). The outcome was generally unfavorable with 14.6% total recovery, 58.7% recovery with sequelae and a case fatality of 26.7%. Conclusion: It emerges from this study that strokes still remain a real public health problem. Knowledge of populations of risk factors as well as their proper management is fundamental in primary preventio

关键词： Cerebrovascular Accident Epidemiology Risk Factors Tivaouane EPS1

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Stroke (Cerebrovascular Accident): Epidemiological, Clinical and Evolving Aspects in the Internal Medicine Department of the Public Health Establishment 1 (EPS1) of Tivaouane

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Open Journal of Internal Medicine（内科学期刊） 2023年第4期

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Assessing the Nutritional Status of Hemodialysis Patients in Sub-Saharan Africa: Experience of Two Hemodialysis Centers in Niger

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Open Journal of Nephrology 2016年第4期6卷 161-166页

作者： Hassan Diongole Moussa zeinabou Maiga Moussa Tondi Yaya Kane Mahamane Aminou Mahamane Sani Ide Abdou Illiassou Touré Aichatou Illa Adehossi Eric Omar Nephrology Department of Zender University Zender Niger Nephrology Department and Internal Medecine of Abdou Moumouni University Niamey Niger Nephrology Department of Assane Seck University Ziguinchor Senegal Hospital Center of Cahors

Introduction: Patients with end-stage chronic renal failure (ESKD) have a significant impairment in their nutritional status. Our study is aiming at evaluating the nutritional status based on clinical and biological parameters. Patient and method: This is a prospective, cross-sectional, descriptive and analytical study carried out in two departments of nephrology/dialysis in Niger from 1 December 2014 to 31 March 2015. The assessment of nutritional status relied on the Body Mass Index (BMI), albuminemia, serum phosphate, hemoglobin, CRP, urea, creatinine levels. Results: Sixty-five patients were involved in the study. The mean age was 44.35 ± 13 years with a sex ratio of 2.09 in favor of men and an average dialysis duration of 43.47 ± 36.55 months. The mean BMI was 21.60 ± 4.47 kg/m2. Undernutrition was noted in 19 patients (29.23%), hypoalbuminemia was found in 13 patients, C-reactive protein (CRP) level was high in 11 patients. In comparative analysis according to the BMI, several parameters were significantly related to undernutrition: hypo-albuminemia, hyperphosphatemia, high CRP, hyperazotemia, anorexia, MUAC, comorbidities, central venous catheter. Conclusion: The prognostic value of undernutrition in chronic hemodialysis patients fosters early recognition and management of all nutritional disturbances in these patients. Assessment and monitoring of nutritional status in chronic hemodialysis require the simultaneous determination of several markers in order to weight the limits of each of the criteria taken in isolation.

关键词： Nutrition Hemodialysis Niger

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Three Dimensional Study of Spectral Response of Polycrystalline Silicon Solar Cells： Vertical Junction Frequency Modulation Scheme

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Journal of Energy and Power Engineering 2013年第5期7卷 903-906页

作者： Nouhou Bako zeinabou Hawa Ly Diallo Aminata Gueye Camarat Moustapha Thiam Dan Maza Abouzeidi Madougou Saidou Gregoire Sissoko Departement de Physique FST Universite de Maradi Maradi 65110 Niger Laboratoire des Semiconducteurs et d'Energie Solaire Departement de Physique FST Universitd Cheikh Anta Diop DakarSenegal Departement de Physique ENS Universite Abdou Moumouni de Niamey Niamey 10 963 Niger

In this paper, the modeling ofa bifacial polycrystalline silicon solar cells vertical junction is presented. The study in dynamic frequency is limited to wavelengths from 400 nm to 1100 nm. The dependence of solar cell spectral response on wavelengths for several modulation frequencies was evaluated by using solar cell internal quantum *** objective is to characterize the polycrystalline silicon in 3D. The effect of frequency modulation pulsation on the phase of internal quantum efficiency was presented as well as values of shunt and series resistance for various grains size values. The results show that the value of maximum internal quantum efficiency is about 50% with a wavelength of 0,82 nm and a frequency of 103 rad/s under monochromatic illumination.

关键词： Solar cell vertical junction polycrystalline silicon frequency modulation internal quantum efficiency wavelength.

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Epidemiology of Sleep Disorders among Chronic Hemodialysis Patients in Senegal: A Multicentric Study

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Health 2016年第1期8卷 42-48页

作者： zeinabou Maiga Moussa Tondi Sidy Mohamed Seck Elhadj Fary Ka Mouhamadou Moustapha Cisse Amadou Diop Dia Diatou Gueye Dia Boucar Diouf Lamine Gueye Nephrology Department Faculty of Health Sciences University Abdou Moumouni Niamey Niger Faculty of Health Sciences University Gaston Berger Saint-Louis Senegal UMI 3189 “Environnement Santé Société UCAD” Dakar Senegal Nephrology Department University Hospital HALD Dakar Senegal

Introduction: Sleep disorders (SD) are common dialysis patients and can impact their quality of life. In previous studies, black ethnicity was associated with higher incidence of SD but a few data are available in African patients. This study aimed to describe prevalence and risk factors of SD among Senegalese dialysis patients. Methods: We performed a cross-sectional study between February 15th and April 30th 2012 including 127 patients (75 males and 52 females) aged 46.8 ± 16.9 (16 - 85 years) and dialysed since >6 months in three dialysis centres. For each patient, we assessed insomnia according to international definition, obstructive sleep apnea syndrome (OSAS) with the Berlin questionnaire, restless leg syndrome (RLS) using abridged version of Cambridge-Hopkins RLS questionnaire, and excessive daytime sleepiness (EDS) with Epworth sleepiness scale. Logistic multivariate regression was used to identify factors associated with different SD. Results: Overall prevalence of SD was 88% comprising: insomnia (64.3%), OSAS (49.1%), RLS (24.1%) and EDS (20.5%). Forty-two patients presented at least two disorders. No difference was noticed in prevalence of SD between genders (p = 0.14). Level of blood pressure were not different across patients with and without SD. Insomnia correlated with anemia, inflammation and EDS. OSAS was associated with age ≥50 years, EDS and neck circumference ≥25 cm. RLS correlated with anemia and EDS. Other parameters such as gender, dialysis vintage, KT/V, obesity, diabetes status and hypoalbuminemia were not associated with the different SD. The majority of patients had not been diagnosed before the survey and none of them was under treatment. Conclusions: Our findings are compatible with high prevalence of sleep disorders reported in other populations. Insomnia and OSAS are the most frequent SD but some patients combined many disorders. Nephrologists should be more aware of these SD in order to detect them early and provide efficient treatme

关键词： Sleep Disorders Hemodialysis Epidemiology Senegal

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Prognosis of Acute Renal Failure of the Child during Severe Malaria in Niamey-Niger

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Open Journal of Nephrology 2018年第1期8卷 10-17页

作者： zeinabou Maiga Moussa Tondi Moumouni Garba Guillaume Mahamat Abderraman Hassane Diongole Moussa Ibrahim Hamat Elmoctar Seydou Toure Ide Abdou Illiassou Soumeila Toure Aboubacar Illiassou Salamatou Niourou Service de Nephrologie Hemodialyse Faculte des sciences de la sante Universite Abdou Moumouni NigerNiameyNiger Service de Pediatrie Hopital National de NiameyNiameyNiger Service de Nephrologie Hemodialyse Hopital de la Renaissance de N’DjamenaN’DjamenaTchad Service de Nephrologie Hopital National de ZinderZinderNiger

Introduction: In malaria-endemic areas, acute renal failure (ARF) is one of the most serious complications, it occurs in 40% of severe forms of malaria in adults and is linked to 75% of deaths, especially when extra-renal cleaning is not available. In children, studies of ARF during malaria are limited. We have no published studies on this topic in Niger. The main objective of our study is to evaluate the prognosis of ARF during severe malaria in children. Patients and Method: This is a one-year prospective study (January 1, 2016 to December 31, 2016) conducted in the resuscitation unit of the pediatric department of the National Lamordé Hospital of Niamey (Niger). We included in the study children aged 0 to 15 years hospitalized for severe malaria with impaired renal function. Patients who had chronic renal failure or who had acute renal failure with a thick negative drop were excluded from the study. Acute renal failure is defined according to Kidney Disease Improving Global Outcomes (KDIGO) criteria basing on creatinine clearance. Results: The incidence of ARF was 12.60%. The mean age of the patients was 4.25 ± 1.3 years [8 months - 15 years]. The mean hemoglobin level was 8.2 ± 2.7 g/dl. In 54.02% of cases, the hemoglobin level is ≤5 g/dl. Mean serum creatinine was 543.7 ± 69.5 μmol/l [107 - 2500 μmol/l] and mean azotemia was 27.5 ± 3.5 mmol/l. Severe anemia (54.02%) were more related to the occurrence of ARF(with p = 0.014). According to the RIFLE classification, 55 patients (63.22%) were in the Risk stage, 18 patients (20.69%) were in the injury stage and 14 patients (16.09%) in the failure stage. All patients were placed on injectable Artesunate. The average length of hospital stay was 8.6 ± 4.5 days [5 to 22 days]. Dialysis was reported in 15/87 (17.24%). For technical and financial reasons only 8 patients were hemodialysed. Indications for dialysis were severe uremic syndrome 7 cases (8.04%), fluid overload 5 cases (5.75%) and severe hyperkalemia 3 cases (3

关键词： Acute Renal Injury Malaria Niger

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Hyperuricemia in Patients with Chronic Renal Failure in the General Hospital of National Reference of N’Djamena (Chad)

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Open Journal of Nephrology 2017年第1期7卷 9-18页

作者： Guillaume Mahamat Abderraman Ibrahim Hamat zeinabou Maiga Moussa Tondi Ahmed Tall Lemrabott Maria Faye Cisse Mouhamadou Moustapha Kossi Akomola Sabi Ka Elhaj Fary Ka Niang Abdou Diouf Boucar Hemodialysis Unit H&#244pital Général de Référence Nationale (HGRN) N’Djamena Tchad Medical Department FSS/ Université Abdou Moumouni de Niamey Service de Néphrologie et Hémodialyse H&#244pital National Lamordé de Niamey Niamey Niger Nephrology service H&#244pital Aristide Le Dantec de Dakar Dakar Sénégal Nephrology and Hemodialysis Service CHU SO Lomé Lomé Togo

Introduction: Hyperuricemia is defined as a level of serum uric acid greater than or equal to 70 mg/l (420 μmol/l) in men and 60 mg/l (360 μmol/l) in women. Several studies have shown that it is a risk factor or a factor of progression of chronic kidney disease. Recent experimental and epidemiological data correlate the association of hyperuricemia with chronic kidney disease (CKD), arterial hypertension and cardiovascular diseases, thus raising the question of the usefulness of therapeutics in the prevention of renal diseases. The objective of this study is to seek a link between chronic kidney disease and hyperuricemia. Materials and Methods: This is a descriptive and analytical study conducted at hemodialysis unit and cardiology service of General Hospital of National reference of N’Djamena (Chad) from 1th January to 1th October 2013 (10 months). We included all chronic kidney disease patients hospitalized in hemodialysis unit and cardiology service who presented associated hyperuricemia. Results: There were 712 CKD patients who were hospitalized. Among them, there were 108 patients who were included in the study and who had hyperuricemia as a prevalence of 15.20%. The average age of patients was 35.5 years and the sex ratio was 3/1. The age group between 40 to 60 years represented 54.6%. There were 41.7% of traders. Hypertensive patients accounted for 49.1%;association of diabetes and hypertension was noted in 12.90%. Renal insufficiency was moderate in 43.5% of patients. Hyperuricemia was present in more than 90% of patients. Profession, age, hematuria, proteinuria and hypertension were statistically positively related to hyperuricemia. Treatment consisted of prescribing allopurinol in 84% of patients. In more than 11% of patients the progression was unfavorable. Conclusion: The implication of hyperuricemia in chronic kidney disease has been proved in several recent studies. However, randomized studies at very long scales have to be carried out to conclude from

关键词： Component Formatting Style Styling

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Profile of Patients with Acute Renal Injury in N’Djamena: About 36 Cases

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Open Journal of Nephrology 2017年第1期7卷 1-8页

作者： Guillaume Mahamat Abderraman Hamat Ibrahim Moussa Tondi zeinabou Maiga Tall Ahmed Lemrabott Faye Maria Kossi Akomola Sabi Mahamat Youssouf Cisse Mouhamadou Moustapha Ka Elhaj Fary Ka Niang Abdou Diouf Boucar Hemodialysis Unit H&#244pital Général de Référence Nationale N’Djamena Tchad Medical Department-FSS/Université Abdou Moumouni de Niamey Service de Néphrologie et Hémodialyse H&#244pital National Lamordé de Niamey Niamey Niger Nephrology service H&#244pital Aristide Le Dantec de Dakar Dakar Sénégal Nephrology and Hemodialysis Service CHU SO Lomé Lomé Togo

Introduction: The incidence of acute renal injury (AKI) has increased in recent decades. Acute renal failure is defined by the abrupt arrest (within hours or days) of the kidney excretory function. Oliguria (urine output 24h) is presented in about half of the cases. The circumstances of the occurrence of AKI are multiple: surgical, traumatic, obstetric, medical, often obvious. Its prognosis depends on the speed of management and the associated organ failure. The objective of this study is to describe the profile of patients in emergency hemodialysis at the Nephrology Unit of the National Reference General Hospital (HGRN) in N’Djamena, Chad. Methods: This was a multicenter, descriptive study in patients with acute renal failure place over a period of 12 months in the emergency departments of the 2 hospitals in N’Djamena. Defined as carriers of an AKI (RIFLE criteria), patients with: 1) Oliguria: urinary output 400 ml/24h ( 350 μmol/l or decrease of GFR by 75%. Results: Of the 311 patients admitted, 36 cases met the inclusion criteria, a frequency of 11.57%. The mean age was 34.46 years with extremes ranging from 7 to 80 years. The female sex predominated with 52.80% as sex ratio of 0.91. Isolated hypertension was noted with 38.88%. Dyspnea accounted for 41.66% of patients admitted to emergency departments. In our series, 50% of our patients had hyperthermia at admission. Oliguria was observed in 41.70% of the cases. Edema accounted for 33.33% of cases. The AKI with the “failure” criterion was 58.34% (21/36), with the criterion “injury” 25% (9 cases) and the criterion “risk” 16.66 (6 cases). AKI were organic in 83.34% (30/36). It was noted that 14 patients, 38.8% had an infectious syndrome. There were 6 patients who had (16.66%) an obstructive AKI, 5 patients (13.88%) had eclampsia, 4 patients (11.12%) had hepatoce

关键词： Acute Renal Injury Hemodialysis Epidemiology Chad Component Formatting Style Styling

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Secondary Hypertension in Sub-Saharan African Populations: A Retrospective Study between 2011 and 2016 at Regional Hospital of Saint-Louis, Senegal

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Open Journal of Nephrology 2016年第3期6卷 93-97页

作者： Yaya Kane Joel Simon Manga Diatou Gueye Dia Maiga Moussa zeinabou Tondi Ahmed Tall Lemrabott Maria Faye Sidy Mouhamed Seck Mouhamadou Moustapha Cisse Alex Ismael Keita Kalilou Diallo El Hadj Fary Ka Abdou Niang Boucar Diouf Nephrology-Cardiology and Internal Medicine Department Assane Seck University Ziguinchor Sénégal Nephrology and Internal Medicine Department Gaston Berger University Saint-Louis Sénégal Nephrology Department Abdou Moumouni University Niamey Niger Nephrology Department Teaching Hospital Aristide Le Dantec Dakar Senegal

Introduction: High blood pressure (HBP) is a worldwide health issue responsible of high cardiovascular morbidity and mortality. Even though essential HBP is far the most frequently reported in patients, secondary causes must be known because of their severity and the possibility of aetiological treatment. No recent epidemiological data are available about secondary causes of HBP in black African populations. The aim of this study was to describe aetiological patterns of secondary HBP in patients followed at Saint-Louis Hospital. Patients and Method: We conducted a retrospective and descriptive study in regional hospital of Saint-Louis. All patients aged ≥15 years old admitted from January 1st 2011 to January 31st 2015 in internal medicine, nephrology, emergency and cardiology departments were included. Clinical, paraclinical data and patients outcomes were collected from medical records. Hypertension was defined according to JNC8 criteria. Secondary HBP was considered if explorations identified a clear aetiology to hypertension. Statistical analysis was done with Excel 2010 and STATA 12.0. Results: We included 9253 patients with mean age of 35 ± 12 years (15 - 83 years) and sex-ratio of 1.6. Overall 67.5% of patients had hypertension and secondary causes were found in 10.5% of them. The majority of patients presented clinical symptoms suggesting a secondary cause of HBP and first-line laboratory explorations were normal in half of cases. Renal diseases were responsible for 79.1% of secondary HBP cases mainly dominated by glomerulonephritis (22.6%), vascular nephropathies (18.7%) and autosomal dominant polycystic kidney disease (5.8%). They were followed by preeclampsia (13.6%) and endocrinal aetiologies such as hyperthyroidism (5.8%), hypercorticism (0.5%), pheochromcytoma (0.5%), primary hyperparathyroidism (0.4%) and Conn’s adenoma (0.1%). Combination of ≥3 antihypertensive drugs was necessary in 71.5% of cases and surgical treatment was performed in three patient

关键词： Secondary High Blood Pressure Internal Medicine Black Africans

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Non-Infectious Complications of Peritoneal Dialysis in Senegal

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Open Journal of Nephrology 2020年第1期10卷 43-49页

作者： Ahmed Tall Lemrabott Maria Faye Moustapha Faye Abdoul Hassane Sanlé Traoré Mouhamadou Moustapha Cissé Khodia Fall Yaya Kane zeinabou Maiga Moussa Tondi Mansour Mbengue Bacary Ba Niakhalee Keita Seynabou Diagne Abdou Niang Boucar Diouf El Hadji Fary Ka Department of Nephrology Aristide Le Dantec University Hospital Dakar Senegal Department of Nephrology Thies University Thies Senegal Internal Medicine and Nephrology Assane Seck University Ziguinchor Senegal Department of Nephrology and Haemodialysis Faculty of Sciences and Health of the Abdou Moumouni University of Niamey Niamey Niger

Introduction: Senegal has pioneered the implementation of peritoneal dialysis (PD) in West Africa, practicing it since 2004. Non-infectious complications are a significant cause of failure of this technique and the transfer of patients to haemodialysis. The aim of this study was to determine the prevalence and the different types of non-infectious complications in our context. Patients and Methods: This was a 5-year, descriptive, retrospective study of patients on chronic peritoneal dialysis for more than 3 months. Results: During the study period, 75 patients were included. The prevalence of non-infectious complications was 88%, including 45.3% mechanical complications and 76% metabolic complications. Catheter migration was the most common mechanical complication (55.9%), followed by catheter blockage (23.5%). Metabolic complications were dominated by hypoalbuminemia (76.3%). Dyslipidaemia and hypokalaemia affected more than 50% of patients, occurring in 59.3% and 56.9% of cases, respectively. Conclusion: In our study, non-infectious complications related to PD were frequent and varied. They remain a significant cause of technical failure. Mechanical complications are often the cause of permanent transfer to haemodialysis.

关键词： Peritoneal Dialysis Non-Infectious Complications Catheter Migration Hypoalbuminemia Hypokalaemia

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