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Ophiostomatales (Ascomycota) associated with Tomicus species in southwestern China with an emphasis on Ophiostoma canum

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Journal of Forestry Research 2020年第6期31卷 2549-2562页

作者： yue Pan Jun Lu Peng Chen zefen yu Huihong Zhang Hui Ye Tao Zhao Eco-development Academy Southwest Forestry UniversityKunming 650224People’s Republic of China Laboratory of Biological Invasion and Ecosecurity Yunnan UniversityKunming 650091People’s Republic of China yunnan Academy of Forestry and Grassland Kunming 650201People’s Republic of China Laboratory for Conservation and Utilization of Bio-resources Key Laboratory Resources of the Ministry of EducationYunnan UniversityKunming 650091People’s Republic of China Department of Science and Technology Orebro University70182 OrebroSweden

Ophiostomatalean fungi may facilitate bark beetle colonization and *** the present study of the fungal community associated with bark beetle species belonging to Tomicus in yunnan,China,six ophiostomatalean fungi(Ophiostoma canum,***,***,Leptographium yunnanense,Leptographium sp.1 and Leptographium sp.2)were isolated from the beetles or their galleries;*** was the most common fungal *** distribution of *** was associated with stands heavily damaged by Tomicus species and a higher percentage of valid galleries of Tomicus yunnanensis and *** in yunnan pine(Pinus yunnanensis).After inoculation of yunnan pine with the fungus,a phloem reaction zone formed and monoterpenes accumulated in the *** results suggested that *** was pathogenic to yunnan pine and that the wide distribution of the fungus might be benefi cial to reproduction of pine shoot beetles in yunnan ***,because the reaction zone and monoterpene accumulation were mild,fungal damage of yunnan pine might be limited.A more integrated study considering all the fungal species should be done to better understand the interactions among bark beetles,blue-stain fungi,and the tree hosts in the region.

关键词： Ophiostomatalean fungi Fungal isolation and identifi cation Ophiostoma canum Pinus yunnanensis Pathogenicity test

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The lifestyle transition of Arthrobotrys oligospora is mediated by microRNA-like RNAs

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Science China(Life Sciences) 2020年第4期63卷 543-551页

作者： Xinglai Ji Heng Li Weihua Zhang Jiai Wang Lianming Liang Chenggang Zou zefen yu Shuqun Liu Ke-Qin Zhang State Key Laboratory for Conservation and Utilization of Bio-Resources in yunnan Yunnan UniversityKunming 650091China Smart Health Big Data Analysis and Location Services Engineering Lab of Jiangsu Province Nanjing University of Posts and TelecommunicationsNanjing 210023China Institute of Medical Biology Chinses Academy of Medical Sciences&Peking Union Medical CollegeKunming 650118China

The lifestyle transition of fungi,defined as switching from taking organic material as nutrients to pathogens,is a fundamental phenomenon in ***,the mechanisms of such transition remain largely *** we show microRNA-like RNAs(milRNAs)play a key role in fungal lifestyle transition for the first *** identified milRNAs by small RNA sequencing in Arthrobotrys oligospora,a known nematode-trapping *** them,7 highly expressed milRNAs were confirmed by northern-blot *** out two milRNAs significantly decreased ***’s ability to switch *** further identified that two of these milRNAs were associated with argonaute protein QDE-2 by RNA-immunoprecipitation(RIP)*** of the predicted target genes of milRNAs were found in immunoprecipitation(IP)products of *** of argonaute gene qde-2 also led to serious defects in lifestyle ***,knocking out individual milRNAs or qde-2 lead to diverse responses under different conditions,and qde-2 itself may be targeted by the ***,it indicates the lifestyle transition of fungi is mediated by milRNAs through RNA interference(RNAi)machinery,revealing the wide existence of miRNAs in fungi kingdom and providing new insights into understanding the adaptation of fungi from scavengers to predators and the mechanisms underlying fungal infections.

关键词： lifestyle transition Arthrobotrys oligospora,microRNA-like RNAs nematode-trapping fungi trap induction fungal adaptation

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Effectiveness and safety of combined nimotuzumab and S-1 chemotherapy with concurrent radiotherapy for locally advanced esophageal cancer in malnourished and elderly patients:A prospective phaseⅡstudy

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Chinese Journal of Cancer Research 2024年第3期36卷 270-281页

作者： Guojie Feng Jiao Li Nuo yu Ziyu Zheng Xiongtao Yang Lei Deng Tao Zhang Wenqing Wang Wenyang Liu Jianyang Wang Qinfu Feng Jima Lyu zefen Xiao Zongmei Zhou Nan Bi Jianjun Qin Xin Wang Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China

Objective:Definitive chemoradiotherapy(dCRT)is the standard treatment for unresectable locally advanced esophageal ***,this treatment is associated with substantial toxicity,and most malnourished or elderly patients are unable to complete this ***,there is a need for a more suitable radiotherapy combination regimen for this *** study was aimed to evaluate the efficacy and safety of a combination regimen comprising chemotherapy with nimotuzumab and S-1 and concurrent radiotherapy for patients with fragile locally advanced esophageal cancer with a high Nutritional Risk Screening 2002(NRS-2002)***:Eligible patients with unresectable esophageal carcinoma who had an NRS-2002 score of 2 or higher were *** were treated with S-1 and nimotuzumab with concurrent radiotherapy,followed by surgery or definitive *** primary endpoint was the locoregional control(LRC)***:A total of 55 patients who met the study criteria were *** completion of treatment,surgery was performed in 15 patients and radiotherapy was continued in 40 *** median follow-up period was 33.3[95%confidence interval(95%CI,31.4−35.1)]*** LRC rate was 77.2%(95%CI,66.6%−89.4%)at 1 year in the entire *** overall survival(OS)rate and event-free survival(EFS)rate were 57.5%and 51.5%at 3 years,*** was associated with better LRC[hazard ratio(HR)=0.16;95%CI,0.04−0.70;P=0.015],OS(HR=0.19;95%CI,0.04−0.80;P=0.024),and EFS(HR=0.25;95%CI,0.08−0.75;P=0.013).Most adverse events were of grade 1 or 2,and no severe adverse events ***:For malnourished or elderly patients with locally advanced esophageal cancer,radiotherapy combined with nimotuzumab and S-1 is effective and has a good safety profile.

关键词： Esophageal carcinoma squamous cell carcinoma nutritional risk score nimotuzumab S-1 definitive chemoradiotherapy

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毒死蜱在土壤中的残留和淋溶动态

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生态环境 2008年第2期17卷 619-622页

作者：周世萍段昌群余泽芬刘宏程西南林学院基础部云南昆明650224 云南大学生命科学学院云南昆明650091 农业部农产品质量监督检验测试中心云南昆明650223

对土壤中毒死蜱的残留和淋溶动态进行了研究。结果显示,毒死蜱在土壤中的残留降解属于一级动力学反应,在土壤中的降解半衰期为63.0d。通过土柱模拟淋溶试验,对毒死蜱在土壤中淋溶的影响因子进行了研究。结果表明,降水量对毒死蜱的淋溶... 详细信息

对土壤中毒死蜱的残留和淋溶动态进行了研究。结果显示,毒死蜱在土壤中的残留降解属于一级动力学反应,在土壤中的降解半衰期为63.0d。通过土柱模拟淋溶试验,对毒死蜱在土壤中淋溶的影响因子进行了研究。结果表明,降水量对毒死蜱的淋溶影响较大,主要表现为降水水量增大,毒死蜱在土层中的最大淋溶深度也随之增加,出现浓度最高峰的土层深度也越大,两者呈正相关关系。与降水量相比,降水强度对毒死蜱的淋溶的影响相对较小。

关键词：毒死蜱降解土壤淋溶

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Linear-Quadratic Pareto Cooperative Game for Mean-Field Backward Stochastic System

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Journal of Systems Science & Complexity 2024年第3期37卷 947-964页

作者： WANG yu School of Control Science and Engineering Shandong UniversityJinan 250061China

This paper focuses on a Pareto cooperative differential game with a linear mean-field backward stochastic system and a quadratic form cost functional. Based on a weighted sum optimality method, the Pareto game is equivalently converted to an optimal control problem. In the first place,the feedback form of Pareto optimal strategy is derived by virtue of decoupling technology, which is represented by four Riccati equations, a mean-field forward stochastic differential equation(MF-FSDE),and a mean-field backward stochastic differential equation(MF-BSDE). In addition, the corresponding Pareto optimal solution is further obtained. Finally, the author solves a problem in mathematical finance to illustrate the application of the theoretical results.

关键词： Backward stochastic differential equation linear-quadratic control mean-field Pareto optimality

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Topological Stability and Entropy for Certain Set-valued Maps

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Acta Mathematica Sinica,English Series 2024年第4期40卷 962-984页

作者： yu ZHANG yu Jun ZHU School of Mathematical Sciences Xiamen UniversityXiamen 361005P.R.China

In this paper,the dynamics(including shadowing property,expansiveness,topological stability and entropy)of several types of upper semi-continuous set-valued maps are mainly considered from differentiable dynamical systems points of *** is shown that(1)if f is a hyperbolic endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has theε-shadowing property,and moreover,if f is an expanding endomorphism then there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has the Lipschitz shadowing property;(2)when a set-valued map F is generated by finite expanding endomorphisms,it has the shadowing property,and moreover,if the collection of the generators has no coincidence point then F is expansive and hence is topologically stable;(3)if f is an expanding endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that h(F_(f,U,ε))=h(f);(4)when F is generated by finite expanding endomorphisms with no coincidence point,the entropy formula of F is ***,the dynamics of the set-valued maps based on discontinuous maps on the interval are also considered.

关键词： Set-valued map orbit space hyperbolic endomorphism perturbation shadowing expansiveness topological stability entropy

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Genomic analyses of nematode-trapping fungi reveal trap evolution and parasitic adaptation

Genomic analyses of nematode-trapping fungi reveal trap evol...

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中国菌物学会2015年学术年会

作者： Xinglai Ji zefen yu Jinkui Yang Jianping Xu Ying Zhang Min Qiao Shuqun Liu Chenggang Zou Xiaowei Huang Xuemei Niu Juan Li Lianming Liang Guohong Li Kaifang Ji Wei Zhou Yajun Liu Lei Li Ke-Qin Zhang Laboratory for Conservation and Utilization of Bio-Resources and Key Laboratory for Microbial Diversity in Southwest ChinaMinistry of EducationYunnan University Department of Biology McMaster University

＜正＞Fungi employ diverse lifestyles as a fundamental strategy to respond to environmental ***,relatively little is known about the underlying mechanisms for lifestyle changes,partly due to the lack of unambiguous lifestyle *** we report the genomes and transcriptomes of representative nematode-trapping fungi（NTF）that can switch from saprophytic to carnivorous lifestyle indicated by

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A new liquid membrane diffusion model for characterizing the adsorption kinetics of europium by using a continuous measurement of adsorption platform

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Nuclear Science and Techniques 2024年第1期35卷 59-72页

作者： Hao-Qi yu Tao yu Jian-Hua Ye State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China CGN Cangnan Nuclear Power Co. Ltd.Cangnan 325800China Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices East China University of TechnologyNanchang 330013China School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China

To explore the kinetic adsorption under continuous and nonequilibrium states, an integration of continuous measurement and adsorption platform kinetics method was proposed, which was initially called the ICM-AP kinetics method, and a corresponding kinetic adsorption experimental method was developed. Adsorption experiments of europium(Eu) on Ca-bentonite,Na-bentonite, and the D231 cation exchange resin were performed using the ICM-AP kinetics method and continuous measurements. Because the kinetic experimental results observed in this study were different from those of traditional batch adsorption data, pseudo-first-order or pseudo-second-order kinetic models were unsuitable for fitting the experimental ***, a liquid membrane diffusion(LMD) model was developed based on the assumption of simultaneous adsorption/desorption to discuss the mechanism of kinetic adsorption. The kinetic adsorption mechanism was also studied by using *** results indicated that the proposed adsorption model can fit the experimental data more suitably, and the adsorption/desorption behaviors of Eu on bentonite and the D231 resin were simultaneously observed, suggesting that the adsorption kinetics of Eu(Ⅲ) was mainly dominated by hydrated Eu(Ⅲ) ions on the liquid membrane.

关键词： ICM-AP method LMD model Adsorption mechanism Eu(Ⅲ)

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Device design principles and bioelectronic applications for flexible organic electrochemical transistors

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International Journal of Extreme Manufacturing 2024年第1期6卷 126-153页

作者： Lin Gao Mengge Wu Xinge yu Junsheng yu State Key Laboratory of Electronic Thin Films and Integrated Devices School of Optoelectronic Science and EngineeringUniversity of Electronic Science and Technology of China(UESTC)Chengdu 610054People’s Republic of China Department of Biomedical Engineering City University of Hong KongHong Kong Special Administrative Region of ChinaPeople’s Republic of China

Organic electrochemical transistors(OECTs) exhibit significant potential for applications in healthcare and human-machine interfaces, due to their tunable synthesis, facile deposition, and excellent biocompatibility. Expanding OECTs to the fexible devices will significantly facilitate stable contact with the skin and enable more possible bioelectronic applications. In this work,we summarize the device physics of fexible OECTs, aiming to offer a foundational understanding and guidelines for material selection and device architecture. Particular attention is paid to the advanced manufacturing approaches, including photolithography and printing techniques, which establish a robust foundation for the commercialization and large-scale fabrication. And abundantly demonstrated examples ranging from biosensors, artificial synapses/neurons, to bioinspired nervous systems are summarized to highlight the considerable prospects of smart healthcare. In the end, the challenges and opportunities are proposed for fexible OECTs. The purpose of this review is not only to elaborate on the basic design principles of fexible OECTs, but also to act as a roadmap for further exploration of wearable OECTs in advanced bio-applications.

关键词： flexible organic electrochemical transistors wearable bioelectronics manufacturing approaches device physics neuromorphic applications

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A guidance and control design with reduced information for a dual-spin stabilized projectile

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Defence Technology（防务技术） 2024年第3期33卷 494-505页

作者： yu Wang Jiyan yu Xiaoming Wang Jia Fangxiu Intelligent Ammunition Technology National Defense Key Discipline Laboratory Nanjing University of Science and TechnologyNanjingJiangsu210094China

In this paper,an integrated guidance and control method based on an adaptive path-following controller is proposed to control a spin-stabilized projectile with only translational motion information under the constraint of an actuator,uncertainties in aerodynamic parameters and measurements,and control system *** to the fairly high rotation speed,the dynamic model of this missile is strongly nonlinear,uncertain and coupled in pitch,yaw and roll channels.A theoretical equivalent resultant force and uncertainty compensation method are comprehensively used to realize decoupling of pitch and *** response to the strong nonlinear and time-varying characteristics of the dynamic system,the quasi-linear model whose parameters are obtained by interpolation of points selected as the segmentation points in the trajectory envelope,is used for calculation in each *** cope with the system uncertainty caused by model approximation,parameter uncertainty and ballistic interference,an extended state estimator is used to compensate the output feedback according to the test ballistic *** order to improve the tracking efficiency and ensure the tracking error convergence with only translational motion information,the virtual guide point,whose derivative is deduced according to the Lyapunov principle,is calculated in real time according to the projection relationship between the real-time position and the reference trajectory,and a virtual line-of-sight angle and the backstepping method are used for the design of the guidance and control *** order to avoid the influence of control input saturation on the guidance and control performance due to the actuator limitation and improve the robustness of the system,an anti-saturation compensator is designed according to the two-step *** feasibility and effectiveness of the path-following controller is verified through closed-loop flight simulations with measurement,control,and condition *** result

关键词： Spin-stabilized projectile Reduced information Path-following control Extended state observer Coupled nonlinear system Input saturation

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