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Non-invasive assessment of liver fibrosis using twodimensional shear wave elastography in patients with autoimmune liver diseases

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World Journal of Gastroenterology 2017年第26期23卷 4839-4846页

作者： Jie zeng ze-ping huang Jian Zheng Tao Wu Rong-Qin Zheng Department of Medical Ultrasonics Third Affiliated Hospital of Sun Yat-Sen University Guangdong Key Laboratory of Liver Disease Research Sun Yat-Sen University Department of Medical Ultrasonics Third Hospital of Longgang

AIM To determine the diagnostic accuracy of two-dimensional shear wave elastography(2D-SWE) for the noninvasive assessment of liver fibrosis in patients with autoimmune liver diseases(AILD) using liver biopsy as the reference *** Patients with AILD who underwent liver biopsy and 2D-SWE were consecutively enrolled. Receiver operating characteristic(ROC) curves were constructed to assess the overall accuracy and to identify optimal cut-off *** The characteristics of the diagnostic performance were determined for 114 patients with AILD. The areas under the ROC curves for significant fibrosis, severe fibrosis, and cirrhosis were 0.85, 0.85, and 0.86, respectively, and the optimal cut-off values associated with significant fibrosis(≥ F2), severe fibrosis(≥ F3), and cirrhosis(F4) were 9.7 k Pa, 13.2 k Pa and 16.3 k Pa, respectively. 2D-SWE showed sensitivity values of 81.7% for significant fibrosis, 83.0% for severe fibrosis,and 87.0% for cirrhosis, and the respective specificity values were 81.3%, 74.6%, and 80.2%. The overall concordance rate of the liver stiffness measurements obtained using 2D-SWE vs fibrosis stages was 53.5%.CONCLUSION2D-SWE showed promising diagnostic performance for assessing liver fibrosis stages and exhibited high cut-off values in patients with AILD. Low overall concordance rate was observed in the liver stiffness measurements obtained using 2D-SWE vs fibrosis stages.

关键词： Autoimmune liver disease Liver fibrosis Two-dimensional shear wave elastography Ultrasound Liver stiffness

Assessment of radiofrequency ablation margin by MRI-MRI image fusion in hepatocellular carcinoma

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World Journal of Gastroenterology 2015年第17期21卷 5345-5351页

作者： Xiao-Li Wang Kai Li Zhong-Zhen Su ze-ping huang ping Wang Rong-Qin Zheng Department of Ultrasound the Third Affiliated Hospital of Sun Yat-sen University

AIM:To investigate the feasibility and clinical value of magnetic resonance imaging(MRI)-MRI image fusion in assessing the ablative margin(AM) for hepatocellular carcinoma(HCC).METHODS:A newly developed ultrasound workstation for MRI-MRI image fusion was used to evaluate the AM of 62 tumors in 52 HCC patients after radiofrequency ablation(RFA).The lesions were divided into two groups:group A,in which the tumor was completely ablated and 5 mm AM was achieved(n = 32);and group B,in which the tumor was completely ablated but 5 mm AM was not achieved(n = 29).To detect local tumor progression(LTP),all patients were followed every two months by contrast-enhanced ultrasound,contrast-enhanced MRI or computed tomography(CT) in the first year after ***,the follow-up interval was prolonged to every three months after the first ***:Of the 62 tumors,MRI-MRI image fusion was successful in 61(98.4%);the remaining case had significant deformation of the liver and massive ascites after *** time required for creating image fusion and AM evaluation was 15.5 ± 5.5 min(range:8-22 min) and 9.6 ± 3.2 min(range:6-14 min),*** follow-up period ranged from 1-23 mo(14.2 ± 5.4 mo).In group A,no LTP was detected in 32 lesions,whereas in group B,LTP was detected in 4 of 29 tumors,which occurred at 2,7,9,and 15 mo after *** frequency of LTP in group B(13.8%;4/29) was significantly higher than that in group A(0/32,P = 0.046).All of the LTPs occurred in the area in which the 5 mm AM was not ***:The MRI-MRI image fusion using an ultrasound workstation is feasible and useful for evaluating the AM after RFA for HCC.

关键词： Hepatocellular carcinoma Radiofrequencyablation Image fusion Magnetic resonance image Ablative margin

改性VO_x/MSU-1催化CO_2氧化异丁烷脱氢

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精细化工 2017年第7期34卷 792-797,840页

作者：孙果宋黄世勇黄青则王秋萍黄媚张雪旺王金淑广西壮族自治区化工研究院广西南宁530006 北京工业大学材料科学与工程学院北京100022

以分子筛MSU-1为载体,La、Ce、Cu和K为改性剂,制备了一系列改性的VO_x/MSU-1催化剂,并系统地评价了催化剂的反应活性。采用XRD、H_2-TPR及NH_3-TPD对改性催化剂La1.0V10.0/MSU-1[w(VO_x)=10.0%,w(La2O_3)=1.0%]进行了表征,并考察了最佳反应条件。结果显示:稀土元素La、Ce的加入能提高催化剂的活性,La元素的加入提高了载体MSU-1上活性组分VO_x的分散度,同时也改善了催化剂表面的酸碱性,更加有利于异丁烷氧化脱氢反应的进行。在最佳反应条件下(温度853 K,体积空速4 800 h^(-1),常压,CO_2与异丁烷体积比为3∶1),催化剂La1.0V10.0/MSU-1上异丁烷的转化率为63.6%,异丁烯的产率为52.3%。稳定性实验结果表明:8 h循环后,催化剂V10.0/MSU-1[w(VO_x)=10.0%]上异丁烷转化率降为16.5%,而La1.0V10.0/MSU-1上为28.8%,说明La改性的VO_x/MSU-1催化剂具有更好的稳定性。

关键词：改性VOx/MSU-1 La2O3 异丁烷氧化脱氢异丁烯 CO2 催化与分离提纯技术

绿色金融是否提高了地方政府对数字经济的注意力?--基于政策文本分析

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生态经济 2025年第1期41卷 106-113,131页

作者：黄平贵州商学院经济与金融学院贵州贵阳550000

在有限理性决策者的注意力稀缺性理论下,地方政策的变化取决于地方政府注意力的变动。反之,地方政府注意力是否取决于其他相关政策的变化?论文挖掘2019—2021年我国30个省级地方政府政策文本数据,用文本中词频反映地方政府在数字经济倾... 详细信息

在有限理性决策者的注意力稀缺性理论下,地方政策的变化取决于地方政府注意力的变动。反之,地方政府注意力是否取决于其他相关政策的变化?论文挖掘2019—2021年我国30个省级地方政府政策文本数据,用文本中词频反映地方政府在数字经济倾注的“注意力”,并应用fsQCA方法探究绿色金融发展是否引起地方政府向数字经济倾注高注意力。研究结论如下:(1)地方政府对数字经济注意力存在“南强北弱”的区域特征。(2)当绿色投资或绿色支持得到发展时,地方政府通过数字技术的应用帮助监测和评估环保项目的效果,实现环境保护、污染治理,助推地方政府向数字经济投入高注意力。(3)当绿色债券和绿色基金同时发展时,作为融资工具,能够有效帮助实体企业获取资金,助力“双碳”,但受公共物品特征影响,很难被反映在企业利润中。并且,绿色债券和绿色基金所应用到的数字手段有限,较难引起高注意力。(4)当绿色金融各个方面发展较弱时,仅绿色债券、绿色权益所能调动的数字技术是不足的,不会促进地方政府向数字经济投入更高注意力。总之,分析绿色金融是否助推地方政府向数字经济投入注意力,对于探索绿色金融和数字经济协同发展路径具有重要意义。

关键词：绿色金融数字经济注意力 fsQCA方法

A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： Xiao Liang Xingping Quan Xiaorui Geng Yujing huang Yonghua Zhao Lei Xi Zhen Yuan ping Wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

常规超声检查与超声造影对肝脏局灶性病变检出能力的比较

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中华肝脏外科手术学电子杂志 2013年第4期2卷 29-33页

作者：黄泽萍王平郑荣琴许尔蛟中山大学附属第三医院超声科中山大学超声诊断与介入超声研究所广州510630

目的比较常规超声检查和超声造影（CEUS）对肝脏局灶性病变（FLL）的检出能力。方法回顾性分析2006年8月至2011年1月在中山大学附属第三医院超声科先后行常规超声检查和CEUS的54例FLL患者临床资料。其中男47例，女7例；年龄（52±15）... 详细信息

目的比较常规超声检查和超声造影（CEUS）对肝脏局灶性病变（FLL）的检出能力。方法回顾性分析2006年8月至2011年1月在中山大学附属第三医院超声科先后行常规超声检查和CEUS的54例FLL患者临床资料。其中男47例，女7例；年龄（52±15）岁。所有患者均签署知情同意书，符合医学伦理学规定。先用B超模式和彩色多普勒超声对肝脏作常规超声检查，然后采用对比脉冲序列特定成像技术，应用造影剂六氟化硫微泡（声诺维）进行CEUS。最终诊断根据增强计算机体层摄影术（CT）或磁共振成像（MRI）、穿刺或手术病理诊断结果及随访结果综合判断。两种检查方法对病灶检出情况比较采用χ^2检验。结果54例中33％（18／54）的患者常规超声检查未见病灶或显示不清，CEUS显示病灶清晰且能作出定性诊断。54例患者中最终确诊178个病灶，其中肝细胞肝癌（肝癌）病灶123个、胆管细胞肝癌病灶7个、转移性肝癌病灶30个、肝血管瘤病灶18个；常规超声检查分别定性诊断46、2、7、7个病灶，CEUS分别为114、5、23、16个病灶，两种方法对肝癌、转移性肝癌及肝血管瘤定性诊断的差异有统计学意义（χ^2=112．083，17．076，9．753；P〈0．05）。常规超声病灶检出率为34．8％（62／178），CEUS检出率为88．8％（158／178），差异有统计学意义（χ^2=109．656，P〈0．05）。75个直径〈10mm的病灶中，常规超声检查检出5个，而CEUS检出66个，差异有统计学薏：义（χ^2=99．510，P〈O．05）；85个直径10～30mm的病灶中，常规超声检查检出39个，而CEUS检出74个，差异有统计学意义（χ^2=32．332，P〈0．05）；直径〉30mm的18个病灶常规超声检查和CEUS均可检出。结论CEUS检出FLL的能力明显优于常规超声检查，尤其能显著提高肝内亚厘米级微小病灶的检出率，具有较高的临床应用价值。

关键词：肝局灶性病变超声检查介入性诊断肝肿瘤

支持IPv4/IPv6双栈的5G通信网络可靠性组网部署研究

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现代电子技术 2025年第1期48卷 102-106页

作者：黄琳黄劼蒋平湖北师范大学计算机与信息工程学院湖北黄石435002 腾讯科技(深圳)有限公司广州深圳518000 湖北理工学院计算机学院湖北黄石435003

5G网络要求更多的基站部署以支持更高的数据传输速率和连接密度。为实现网络数据的并行高速传输,确保网络应用业务的实时性和稳定性,文中提出一种支持IPv4/IPv6双栈的5G通信网络可靠性组网部署方法。结合IPv4和IPv6双栈,构建双栈转换机... 详细信息

5G网络要求更多的基站部署以支持更高的数据传输速率和连接密度。为实现网络数据的并行高速传输,确保网络应用业务的实时性和稳定性,文中提出一种支持IPv4/IPv6双栈的5G通信网络可靠性组网部署方法。结合IPv4和IPv6双栈,构建双栈转换机制结合有限双协议栈模型,在模型下构建5G通信网络结构,并通过高架立体交叉网优化IPv4/IPv6双栈的5G通信网络组网结构,提升IPv4/IPv6双栈5G通信网络的通信速度。采用冗余路径算法,实现5G网络IPv4/IPv6双栈通信中的服务功能链编排,解决IPv4/IPv6双栈通信中的冗余问题。实验结果表明,该方法能够构建一种更稳定、更高效的5G通信网络组网结构,提高了网络频谱效率,优化了网络环境。

关键词： 5G通信网络 IPv4/IPv6双栈可靠性组网部署服务功能链冗余路径算法有限双协议栈模型

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A general stabilizing strategy based on vitamin C for n-type organic semiconductors

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Science China Materials 2025年第01期 303-304页

作者： Hui huang College of Materials Science and Opto-Electronic Technology Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

Organic semiconductors (OSCs), as an emerging next-generation semiconductor material, hold promising prospects in fields such as flexible displays, electronic skins, smart healthcare,and the Internet of Things, due to their excellent flexibility,solution processability, and tunable band structures [1,2]. These molecules are often classified into n-type and p-type, depending on whether the prevalent charge carriers are electrons or holes[3].

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Efficient white-light-emitting lead-free halide double perovskites enabling full-spectrum pc-WLEDs

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Science China Materials 2025年第1期 305-306页

作者： Xiaoyong huang College of Physics and Optoelectronics Taiyuan University of Technology

With the rapid development of solid-state lighting, an important goal of phosphor-converted white light-emitting diodes (pc-WLEDs) is to provide a healthy and comfortable fullspectrum artificial light source with a co...

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