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Psychological impact of the COVID-19 pandemic on Chinese population:An online survey

World Journal of Clinical Cases 2021年第31期9卷 9500-9508页

作者： Taif shah zahir shah Nafeesa Yasmeen Zhong-Ren Ma Faculty of Life Science and Technology Kunming University of Science and TechnologyKunming 650500Yunnan ProvinceChina College of Veterinary Sciences The University of Agriculture PeshawarPeshawar 25120KPPakistan College of Veterinary Medicine South China Agricultural UniversityGuangzhou 510642Guangdong ProvinceChina Biomedical Research Center Northwest Minzu University Gansu ChinaLanzhou 730030Gansu ProvinceChina

BACKGROUND The ongoing coronavirus disease 2019(COVID-19)pandemic infiltrates every aspect of our life,including the psychological *** has experienced the first wave of this epidemic,and it is now affecting the global *** This study aimed to investigate the prevalence and associated factors of posttraumatic stress disorder(PTSD)among the general Chinese *** A detailed questionnaire,comprising of 38 questions designed in both English and Chinese,was *** survey was conducted via WeChat,a multipurpose messaging,social media,and mobile payment app,which is widely used by the Chinese *** In total,1082 individuals from 31 provinces,autonomous regions,and municipalities participated in the survey by filling the questionnaires through the WeChat app.97.8%of the participants had an Impact of Event-Scale-Revised(IES-R)total score above 20,which is an indicator of *** IES-R total and all the three subscales,including intrusion,avoidance,and hyperarousal,are significantly correlated with *** addition,age,profession,marital status,and level of education are significantly correlated with the degree of PTSD *** The COVID-19 epidemic has widely caused PTSD among the general Chinese *** results bear important implications for regions struggling with the pandemic to implement effective interventions to cope with these mental health problems.

关键词： COVID-19 Post-traumatic stress disorder Impact of Event-Scale-Revised China

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Quality and Crop Yield Potential of Moderately Degraded Alfisols Under Different Nutrient Inputs and Cropping Patterns

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Pedosphere 2019年第2期29卷 235-247页

作者： Wiqar AHMAD Farmanullah KHAN zahir shah Muhammad Jamal KHAN Department of Soil and Environmental Sciences The University of Agriculture PeshawarAMK Campus Department of Soil and Environmental Sciences The University of AgriculturePeshawar

Crop performance on degraded soil needs special management practices to overcome soil quality limitations. In a 2-year(from summer 2006 to winter 2007–2008) field trial on a moderately degraded Alfisol in Swabi District(34°7′12′′N, 72°28′20′′E), Pakistan,the effects of three cropping patterns, cereal-cereal(CC), cereal-legume(CL), and cereal-cereal and legume intercrop(CLI), were tested in main plots under four fertilization treatments in sub-plots, including no fertilization(control), farmers' practice(FP, 60:45 kg ha^(-1) N:P_2O_5), recommended dose(RD, 120:90:60 kg ha^(-1) N:P_2O_5:K_2O), and integrated nutrient management(INM, 20 t ha^(-1) farmyard manure integrated with 50% N, 100% P, and K of recommended dose), using a split-plot randomized complete block design. The performance of CL was superior than CC in plant height, leaf area index(LAI), cob length, grain yield, biological yield, and grain protein(8%, 26%, 8%, 5%, 10%, and 8% increases, respectively), while CLI confirmed significant improvement only in LAI(25%) over CC. Response to nutrient inputs from all sources was in the order of INM > RD > FP > control, and the maximum net economic return by INM(23% and 2.5 times higher than RD and FP, respectively) indicated severe deficiency of both macro-and micro-nutrients in the soil as well as degraded physical properties. Increases in soil organic matter, total N, total mineral N, available P and K, total porosity, and available water-holding capacity by 6%, 34%, 24%, 50%, 13%, 5%, and 7%, respectively, and decrease in soil bulk density by 4% after four crop seasons indicated optimistic changes in soil quality as a result of the combined effects of fertilization from organic and inorganic sources and legumes within crop rotation. This study suggests that keeping the soil covered under cereal-legume rotation crops all year round and treatment with INM(50% N from organic source and 50% from inorganic source) are the best management practice for sustained produc

关键词： crop rotation crop performance degraded soil farmyard manure integrated nutrient management legume intercrop sustained production

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Log-normal flux distribution of bright Fermi blazars

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Research in Astronomy and Astrophysics 2018年第11期18卷 111-122页

作者： zahir shah Nijil Mankuzhiyil Atreyee Sinha Ranjeev Misra Sunder Sahayanathan Naseer Iqbal Department Of Physics University of KashmirSrinagar-190006India Astrophysical Sciences Division Bhabha Atomic Research CentreMumbai-400085India in Inter-University Centre for Astronomy and Astrophysics Pune-411007India AstroParticule et Cosmoligie CNRS/University Paris Diderot10Rue Alice Domon et Leonie DuquetParis 75013France

We present the results of the γ-ray flux distribution study on the brightest blazars which were observed by Fermi-LAT. We selected 50 of the brightest blazars based on the maximum number of detections reported in the Third LAT AGN Catalog. We performed standard unbinned maximum likelihood analysis on the LAT data during the period between August 2008 and December 2016, in order to obtain the average monthly flux. After quality cuts, blazars for which at least 90% of the total flux had survived were selected for further study, and this included 19 FSRQs and 19 BL Lacs. The Anderson-Darling and χ2 tests suggest that the integrated monthly flux follows a log-normal distribution for all sources, except for three FSRQs for which neither a normal nor a log-normal distribution was preferred. A double log-normal flux distribution tendency was observed in these sources, though this has to be confirmed with improved statistics. We also found that the standard deviation of the log-normal flux distribution increases with the mean spectral index of the blazar, and can be fitted with a line of slope 0.24±0.04. We repeat our study on three additional brightest unclassified blazars to identify their flux distribution properties. Based on the features of their log-normal flux distribution, we infer these unclassified blazars may be closely associated with FSRQs. We also highlight that considering the lognormal behavior of the flux distribution of blazars, averaging their long term flux on a linear scale can largely underestimate the nominal flux and this discrepancy can propagate down to the estimation of source parameters through spectral modeling.

关键词： active galaxy: blazar FSRQ BL Lac gamma-rays

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Current approaches to reduce or eliminate mitochondrial DNA mutations

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Science China(Life Sciences) 2016年第5期59卷 532-535页

作者： Liang Yang Tingfang Mei Xiaobing Lin Haite Tang Yi Wu Rui Wang Jinglei Liu zahir shah Xingguo Liu Key Laboratory of Regenerative Biology Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine South China Institute for Stem Cell Biology and Regenerative Medicine Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences

Mitochondrial DNA （mtDNA） mutations have been impli- cated in a broad range of disorders which severely affect human health （Wallace, 1999）. Some drugs have been developed to slow down pathological changes of mitochon- drial disorders. However, there is no effective treatment for patients with mtDNA mutations, mtDNA is less protected and has fewer repair mechanisms than nuclear DNA （nDNA）. Such a reality results in a much higher mutation rate in mtDNA than that in nDNA. The mixture of mutated mtDNA versus wild-type mtDNA is known as hetero- plasmy. Mitochondrial threshold effect refers to the fact that mtDNA mutation must accumulate to high proportions （60%-90%） before respiratory activity is affected （Schon et al., 2012）. It is feasible to selectively reduce the levels of mu- tated mtDNA while sparing wild-type mtDNA to skew this ratio back to a healthier range. Here, we describe the link between mtDNA mutation and mitochondrial diseases, and we summarize several newly developed approaches with regard to the reduction or elimination of mtDNA mutation in mammals. These methods include nuclear gene modula- tion, molecular approaches targeting mutated mtDNA, mtDNA replacement, and induced pluripotent stem cell （iPSC） modeling. These various methods have their own advantages and limitations.

关键词：线粒体DNA突变基因突变 mtDNA突变线粒体疾病人类健康核DNA 多能干细胞病理变化

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CFRP在不同温度下的机械和冲击特性

CFRP在不同温度下的机械和冲击特性

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作者： zahir shah 西安科技大学

学位级别：硕士

随着碳纤维增强材料(CFRP)质量的提高,对现场分析的需求将增加。几家公司声称碳纤维在恶劣条件下(包括低温)使用时的固定优势。然而,对织物的温度暴露行为的研究很少。必须彻底调查每一件有用的东西的威力和弱点。本研究规定了CFRP截面... 详细信息

随着碳纤维增强材料(CFRP)质量的提高,对现场分析的需求将增加。几家公司声称碳纤维在恶劣条件下(包括低温)使用时的固定优势。然而,对织物的温度暴露行为的研究很少。必须彻底调查每一件有用的东西的威力和弱点。本研究规定了CFRP截面。该项目的目标是使用各种热背景测试CFRP的力学性能。该方法在不同的分章中针对所执行的三种测试类型中的每一种进行了介绍;四点弯曲试验、气枪冲击试验和夏比冲击试验。对于四点弯曲试验和气枪冲击试验,也有代表实验试验和数值分析的下切面。对于夏比试验,仅进行了实验试验。存在一个四点弯曲搜索来评估CFRP在高温下的折射,以及后来显示接近低温的现状。进行数学检查以补充和确认CFRP面积的研究结果。使用空气喷射器压痕扫描,研究了与CFRP上的冰冲击相关的弹丸冲击的视觉效果。通过分层CFRP截面测量渗透性,以评估喷丸扩散的调节厚度。结果与那些数学考试保持一致。采用夏比冲击试验对CFRP的断裂韧性进行了定性和定量评估。研究结果表明,当CFRP试样暴露在低温下时,其力学性能会恶化。根据第二部分,银桥的几个机械部件,特别是梁和捆绑,需要重新组合和加固,目前在几个国家正在进行。因此,CFRP的使用被认为具有巨大的潜力,在过去三十年中,已经开展了许多实验室研究,以调查CFRP加固重要粘附物的性能。通过创建结构解决方案以建立风格程序,需要进行额外的研究,以了解这些组合成分和形状的机械响应和坚固性,以及它们在碳纤维增强聚合物加强连接时的适合性。以及适当的其他加固方法列表。本论文的主题之一是碳纤维增强聚合物的粘结运动报告,它可以在自动或电流加载下加强连接。除了保留一项基本技术来近似反应罐并将其与研究结果相匹配外,还对许多保证长度的双带接头施加了同时加载。然后,使用拟循环和循环措施确定接头承受这些形式荷载的能力。测量耗散能量,并将其连接到碳纤维增强聚合物带之间的误差附近,从而连接到增强板,以检查界面处发生的损伤。该方法在不同的分章中针对所执行的三种类型的测试中的每一种进行了介绍;四点弯曲试验、气枪冲击试验和夏比冲击试验。对于四点弯曲试验和气枪冲击试验,也有代表实验试验和数值分析的下切面。对于夏比试验,仅进行了实验试验。通过查看所有结果,可以合理地得出结论,当暴露在寒冷中时,CFRP样品的强度会有所降低。很难确切地说出到底减少了多少,但估计力量减少约10%似乎是现实的。通过查看所有结果,可以合理地得出结论,当暴露在寒冷中时,CFRP样品的强度会有所降低。很难确切地说出到底减少了多少,但估计力量减少约10%似乎是现实的。四点弯曲试验中,CFRP试样在低温下的挠度超过了区温试验项目。区域回火碳纤维增强聚合物观察项目的数值结果与实验结果相匹配后,观察到17,48 N的差异。根据数值解,存在的极限介于1.59毫米和1.63毫米之间。

关键词：钢桥加固修复粘结应力高模量CFRP

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Short-form OPA1 is a molecular chaperone in mitochondrial intermembrane space

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Science China(Life Sciences) 2022年第2期65卷 227-235页

作者： Deyang Yao Yukun Li Sheng Zeng Zhifan Li zahir shah Bigui Song Jinglei Liu Yi Wu Liang Yang Qi Long Wenqian Wang Zhijuan Hu Haite Tang Xingguo Liu School of Life Sciences University of Science and Technology of ChinaHefei 230027China Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) CAS Key Laboratory of Regenerative BiologyJoint School of Life SciencesGuangzhou Institutes of Biomedicine and HealthChinese Academy of SciencesGuangzhou Medical UniversityGuangzhou 510530China Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine Institute for Stem Cell and RegenerationGuangzhou Institutes of Biomedicine and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesGuangzhou 510530China Centre for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong SARChina

Mitochondria,double-membrane organelles,are known to participate in a variety of metabolic and signal transduction *** intermembrane space(IMS)of mitochondria is proposed to subject to multiple damages emanating from the respiratory *** optic atrophy 1(OPA1),an important protein for mitochondrial fusion,is cleaved into soluble short-form(S-OPA1)under *** we report that S-OPA1 could function as a molecular chaperone in *** purified the S-OPA1(amino acid sequence after OPA1 isoform 5 S1 site)protein and showed it protected substrate proteins from thermally and chemically induced aggregation and strengthened the thermotolerance of Escherichia coli(***).We also showed that S-OPA1 conferred thermotolerance on IMS proteins,e.g.,*** chaperone activity of S-OPA1 may be required for maintaining IMS homeostasis in mitochondria.

关键词： mitochondria OPA1 chaperone mitochondrial homeostasis heat shock

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Integrated Effects of Rhizobial Inoculum and Inorganic Fertilizers on Wheat Yield and Yield Components

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American Journal of Plant Sciences 2014年第13期5卷 2066-2073页

作者： Muhammad Adnan zahir shah Asif Khan Muzamil shah Gohar Ali Khan Azaz Ali Nisar Ali Khan Nouman Saleem shah Nawaz Saba Akbar Sonia Samreen Kanwal Zaib Department of Plant Breeding and Genetics The University of Agriculture Peshawar Pakistan Department of Soil and Environmental Sciences The University of Agriculture Peshawar Pakistan

An experiment was conducted in pots under natural condition with two factor factorial completely randomized design (CRD) (CRD) to investigate the integrated effect of rhizobia inoculums and inorganic fertilizers on growth and yield of wheat crop at The University of Agriculture Peshawar, during 2012-2013. The experiment was comprised of four inoculums (no, lentil, peas and chickpeas) and two NPK levels (recommended 120:90:60 kg·ha-1 & 20% less of recommended). It was observed that inoculation of wheat by rhizobia significantly increased tillers per plant by a maximum of 42%, plant height by 13%, grain per spike by 16%, 100 grain weight by 10%, biological and grain yield by 10% over un-inoculated (control) treatment. Among inoculums, peas inoculum was found to be the most efficient for all traits except plant height where chickpea inoculum performed better. Similarly recommended NPK significantly increased tillers per plant by 33%, plant height by 19%, grain per spike by 9%, 100 grain weight by 10%, biological yield by 8% and grain yield by 10% compared with 20% less of recommended NPK. Interactive effect of inoculum x NPK was significant for tillers per plant, grain per spike, grain yield and non-significant for plant height, 100 grain weight and biological yield. However, it was evident from the results that inoculation improved all traits both under recommended and 20% less of recommended NPK. The persistent good performance of peas and lentil rhizobial inoculation in wheat growth exhibited that this could be used as a plant growth promoting rhizobacteria for wheat and other cereal crops in prevailing soil and climatic conditions.

关键词： Yield Components Rhizobial Inoculum Wheat Recommended NPK Inorganic Fertilizer

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Assessment of Retreatment Tuberculosis Cases amongst All Tuberculosis Cases Notification in District Swat 2015-2017: A Retrospective Cohort Review

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Journal of Tuberculosis Research 2019年第1期7卷 11-18页

作者： zahir shah Maqsood Ali Khan Hina Najmi Razia Fatima Aashifa Yaqoob Abdul Ghafoor Ahmed Wali Amjad Khan shah Hasan Khan Ghulam Mustafa Halepota Provincial Tuberculosis Control Program Swat Khyber Pakhtunkhwa Pakistan Sukh Initiative Aman Health Care Services Karachi Pakistan National Tuberculosis Control Program Islamabad Pakistan Provincial Tuberculosis Control Program Quetta Pakistan Pakistan Kidney and Liver Institute & Research Center Lahore Pakistan

Retreatment Tuberculosis (TB) has long been a neglected area in global TB control. To determine the notification of re-treatment Tuberculosis TB cases among all enrolled TB patients, we conducted a retrospective cohort review of routine program data from 2015-2017. A total of 8663 tuberculosis cases (all new and old forms) were registered at the study site. Of these, 1916 (22%) were pulmonary bacteriological confirmed;3498 (40.37%) were pulmonary clinical diagnosed and 3396 (39.20%) were clinically or bacteriological confirmed extra-pulmonary tuberculosis cases. Retreatment cases trend was found to be increased from 1% in 2015 to 1.6% in 2017. Majority of re-treatment cases were in the age group 18 - 43 years and only 7 patients were under the age of 15 years. This concludes that notification of re-treatment cases is very low among all enrolled TB patients and this could be possibly due to the fact that most of the re-treatment cases were registered as new cases or misdiagnosed. There is need and space to increase retreatment cases. Most of the re-treatment cases were usually converted to MDR-TB (Multi-Drug Resistant Tuberculosis) as noted in PMDT (Programmatic management of Drugs resistant tuberculosis) site. Therefore, proper history and diagnosis should be encouraged at the time of case notification.

关键词： Retreatment TB Cases Retrospective Cohort Swat Pakistan

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Alternative Strategy for Development of Dielectric Calcium Copper Titanate‑Based Electrolytes for Low‑Temperature Solid Oxide Fuel Cells

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Nano-Micro Letters 2025年第1期17卷 310-332页

作者： Sajid Rauf Muhammad Bilal Hanif Zuhra Tayyab Matej Veis MAKYousaf shah Naveed Mushtaq Dmitry Medvedev Yibin Tian Chen Xia Martin Motola Bin Zhu College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Department of Inorganic Chemistry Faculty of Natural SciencesComenius University BratislavaIlkovicova684215 BratislavaSlovakia Energy Storage Joint Research Center School of Energy and EnvironmentSoutheast UniversityNanjing 210096People’s Republic of China Hydrogen Energy Laboratory Ural Federal University620002 EkaterinburgRussia Laboratory of Electrochemical Devices Based on Solid Oxide Proton Electrolytes Institute of High Temperature Electrochemistry620066 EkaterinburgRussia School of Microelectronics Hubei UniversityWuhan 430062People’s Republic of China

The development of low-temperature solid oxide fuel cells(LT-SOFCs)is of significant importance for realizing the widespread application of *** has stimulated a substantial materials research effort in developing high oxide-ion conductivity in the electrolyte layer of *** this context,for the first time,a dielectric material,CaCu_(3)Ti_(4)O_(12)(CCTO)is designed for LT-SOFCs electrolyte application in this *** individual CCTO and its heterostructure materials with a p-type Ni_(0.8)Co_(0.15)Al_(0.05)LiO_(2−δ)(NCAL)semiconductor are evaluated as alternative electrolytes in LT-SOFC at 450–550℃.The single cell with the individual CCTO electrolyte exhibits a power output of approximately 263 mW cm^(-2) and an open-circuit voltage(OCV)of 0.95 V at 550℃,while the cell with the CCTO–NCAL heterostructure electrolyte capably delivers an improved power output of approximately 605 mW cm^(-2) along with a higher OCV over 1.0 V,which indicates the introduction of high hole-conducting NCAL into the CCTO could enhance the cell performance rather than inducing any potential short-circuiting *** is found that these promising outcomes are due to the interplay of the dielectric material,its structure,and overall properties that led to improve electrochemical mechanism in CCTO–***,density functional theory calculations provide the detailed information about the electronic and structural properties of the CCTO and NCAL and their heterostructure CCTO–*** study thus provides a new approach for developing new advanced electrolytes for LT-SOFCs.

关键词： LT-SOFCs Dielectric CaCu_(3)Ti_(4)O_(12) Semiconductor Ni_(0.8)Co_(0.15)Al_(0.05)LiO_(2−δ) Ionic conductivity Heterostructure electrolyte

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Restless head syndrome:A retrospective study

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World Journal of Methodology 2025年第1期15卷 51-59页

作者： Sanjay Prakash Varoon Vadodaria Niraj Chawda Chetsi S shah Anurag Prakash Department of Neurology Smt.B.K.Shah Medical Institute and Research CentreSumandeep VidyapeethVadodara 391760GujarātIndia Department of Medicine Smt.B.K.Shah Medical Institute and Research CentreSumandeep VidyapeethVadodara 391760GujarātIndia Department of Medicine Parul Institute of Medical Sciences and Research CentreParul University WaghodiaVadodara 391760India

BACKGROUND Restless legs syndrome(RLS)is characterized by an urge to move with an unpleasant sensation in the lower *** typically affects the ***,it can also affect several other body regions,such as the arms,abdomen,face,neck,head,and genital *** are only a few reports of the RLS variant affecting the *** To assess the epidemiological,clinical,and other aspects of the RLS variant affecting the *** We conducted a retrospective study of 17 adult patients(>18 years)who met the RLS criteria and simultaneously experienced RLS-like symptoms in the *** The median age at which symptoms appeared was 41.6 *** and females were equally affected(1.1:1).All 17 patients had uncomfortable sensations in the lower *** or disturbed sleep was the most common comorbidity(n=16,88.2%).However,headache was the most common presenting or primary symptom(n=10,70.5%).Dizziness or an abnormal sensation in the head was the second most common presenting symptom(5 patients,29.4%).Other presenting features were leg pain,backache,and generalized body *** patients responded favorably to dopaminergic *** If RLS-related unpleasant sensations and pain are felt in the head,they may be misinterpreted as headache,dizziness,or psychosomatic *** and headaches in a subset of patients may be two phenotypic manifestations of the same disorder.

关键词： Restless legs syndrome Restless head syndrome Dopamine Headache Migraine Tension-type headache

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