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A three-dimensional variational ocean data assimilation system:Scheme and preliminary results

Science china Earth sciences 2006年第11期49卷 1212-1222页

作者： zhu jiang1,2. zhou guangqing1,{2., fu weiwei1 & you xiaobao1,3.1. international center for climate and environment sciences, institute of atmospheric physics, chinese academy of sciences, Beijing 10002., china 2. jiangsu Key Laboratory of Meteorological Disaster, Nanjing University of Information Science and Technology, Nanjing 2.0044, china 3. Beijing institute of Applied Meteorology, Beijing 10002., china 1. international center for {2. and environment sciences Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China 2. jiangsu Key Laboratory of Meteorological Disaster Nanjing University of Information Science and Technology Nanjing 210044 China 3. Beijing institute of Applied Meteorology Beijing 100029 China

A new 3DVAR-based Ocean Variational Analysis System (OVALS) is developed. OVALS is capable of assimilating in situ sea water temperature and salinity observations and satellite altimetry data. As a component of OVALS, a new variational scheme is proposed to assimilate the sea surface height data. This scheme considers both the vertical correlation of background errors and the nonlinear temperature-salinity relationship which is derived from the generalization of the linear balance constraints to the nonlinear in the 3DVAR. By this scheme, the model temperature and salinity fields are directly adjusted from the altimetry data. Additionally, OVALS can assimilate the temperature and salinity profiles from the ARGO floats which have been implemented in recent years and some temperature and salinity data such as from expendable bathythermograph, moored ocean buoys, etc. A 2.-year assimilation experiment is carried out by using OVALS and the Tropical Pacific circulation model. The results show that the assimilation system may effectively improve the estimations of temperature and salinity by assimilating all kinds of observations. Moreover, the root mean square errors of temperature and salinity in the upper depth less than 42. m reach 0.63℃ and 0.34 psu.

关键词： data assimilation, 3DVAR, sea surface height, ARGO floats.

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Improved ENSO simulation in regional coupled GCM using regressive correction method

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Science china Earth sciences 2007年第8期50卷 1258-1265页

作者： fu weiwei1 & zhou {2.2.1 Nansen-zhu international Research center (NZC), institute of atmospheric physics, chinese academy of sciences (CAS), Beijing 10002., china 2.State Key Laboratory of Numerical Modeling for atmospheric sciences and Geophysical Fluid Dynamics (LASG), {12. of At-mospheric physics, CAS, Beijing 10002., china 1. Nansen-zhu international Research {2. (NZC) Institute of Atmospheric Physics Chinese Academy of Sciences (CAS) Beijing 100029 China 2. State Key Laboratory of Numerical Modeling for atmospheric sciences and Geophysical Fluid Dynamics (LASG) Institute of Atmospheric Physics CAS Beijing 100029 China

A regressive correction method is presented with the primary goal of improving ENSO simulation in regional coupled GCM. It focuses on the correction of ocean-atmosphere exchanged fluxes. On the basis of numerical experiments and analysis, the method can be described as follows: first, driving the ocean model with heat and momentum flux computed from a long-term observation data set; the pro-duced SST is then applied to force the AGCM as its boundary condition; after that the AGCM’s simula-tion and the corresponding observation can be correlated by a linear regressive formula. Thus the re-gressive correction coefficients for the simulation with spatial and temporal variation could be obtained by linear fitting. Finally the coefficients are applied to redressing the variables used for the calculation of the exchanged air-sea flux in the coupled model when it starts integration. This method together with the anomaly coupling method is tested in a regional coupled model, which is composed of a global grid-point atmospheric general circulation model and a high-resolution tropical Pacific Ocean model. The comparison of the results shows that it is superior to the anomaly coupling both in reducing the coupled model ‘climate drift’ and in improving the ENSO simulation in the tropical Pacific Ocean.

关键词： anomaly coupling regressive correction method regional coupled model ENSO simulation

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Doping-driven dual heterogeneous interfacial structures boosting the durability of industry-compatible water splitting at high current density

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Science china Chemistry 2024年第10期67卷 3468-3481页

作者： Chunming yang Lihai zhou Zhijie Kong Xiang Li Wangchuan {2. guangqing Wang yanzhong Zhen Feng fu Yucang Liang Research institute of Comprehensive Energy Industry Technology College of Chemistry&Chemical EngineeringYan’an UniversityYan’an 716000China Henan Key Laboratory of Crystalline Molecular functional Materials Green Catalysis CenterCollege of ChemistryZhengzhou UniversityZhengzhou 450001China Institut für Anorganische Chemie Eberhard Karls UniversitätTübingen 72076Germany

Developing highly stable electrocatalysts under industry-compatible current densities(>500 mA cm^(-2.)in an anion-exchange membrane water electrolyzer(AEMWE)is an enormous challenge for water ***,based on the results of density function theory calculations,a dual heterogeneous interfacial structured NiSe/Fe-Ni(OH)_(2.catalyst was subtly designed and successfully prepared by electrodepositing Fe-doped Ni(OH)_(2.on NiSe-loaded nickel foam(NF).Fe doping-driven heterogeneous structures in NiSe/Fe-Ni(OH)_(2.markedly boost catalytic activity and durability at industrially compatible current densities in single hydrogen and oxygen evolution reactions under alkaline *** particular,NiSe/Fe-Ni(OH)_(2.shows a negligible performance loss at 600 mA cm^(-2.at least 1,000 h for overall water splitting,a distinguished long-term durability acting as AEMWE electrodes at 600 mA cm^(-2.and 1 A cm^(-2.at 85℃for at least 95 *** to Fe doping-induced strong synergetic effect between Ni and Fe,dual heterostructure-promoted charge transfer and redistribution,abundant catalytic active sites,and improvement of stability and durability,a mechanism of Fe doping-driven heterogeneous interfacial structurepromoted catalytic performance was *** study provides a successful example of theory-directed catalyst preparation and pioneers a creative strategy for industry-compatible water splitting at high current density.

关键词： doping-induced heterojunction structure NiSe/Fe-Ni(OH)_(2. large current density anion-exchange membrane industrycompatible water electrolysis

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Status of aquatic organisms resources and their environments in yangtze River system(2.17-2.2.)⋆

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Aquaculture and Fisheries 2024年第5期9卷 833-850页

作者： Haile yang Li Shen Yongfeng He Huiwu Tian Lei Gao Jinming Wu Zhigang Mei Nian Wei Lin Wang Tingbing zhu Feifei Hu Jinling Gong Hongchun Du Xinbin Duan Huatang Deng Daoqun Wang Fengyue zhu Yunfeng Li Fan Wu Huijun Ru yan Zhang Junyi Li Junlin yang Yuntao zhou Dongdong Fang Yinping Wang Danqing Lin yanping yang Peijie Li Silei Liu Jian yang Ping zhuang Sikai Wang Tao Zhang Gang yang Wenbo yang Lilai Yuan Kun Cao Shuo Xu Huiyuan Liu Zhiqiang Liang Chongrui Wang Hong Li Xiping Yuan Xin yang Yilong fu yanping Zhang Haixin Zhang Zhiying Tao Sheng Wang Xiaoping Gao Binsong Jin Kemao Li Guojie Wang Shenglong Jian Yingqin Li Chenjiang Xue Chunyun Lei Shaowei Xue Yi Sun Bin zhu Ke Shao Xingkun Hu Meihua Xiong Jun Du Bin He Tao yan Yingying Huang Yuanchao Zou Biwen Xie Yongming Wang Bin Li Fei Liu Yaoyao Zhang Fei Fan Zhijian Wang Jing Huang Haoran Gu Hailong Ge yan Dan yan Li Shuqiao Wang Chuang Zhang Lu zhou Xue Wang Sheng Zeng yan Xiang Xugang He Jianhui Qin Chengxing Xia Jie Hou Yifu Shi Lifang Gao Zhiqiang zhu Hongbao Shen Yun Du Xuejun Duan Jiawu Xiong Deguo yang Shaoping Liu Zhaohui Ni Hui Zhang Kai Liu Feng Zhao Yingren Li Jianwei Wang Qiwei Wei yangtze River Fisheries Research institute Chinese Academy of Fishery SciencesWuhan430223China institute of Hydrobiology Chinese Academy of SciencesWuhan430072China Fishery Resource and environment Research center Chinese Academy of Fishery SciencesBeijing100141China Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization Ministry of Agriculture and Rural AffairsFreshwater Fisheries Research CenterChinese Academy of Fishery SciencesWuxi214081China East china Sea Fisheries Research institute Chinese Academy of Fishery SciencesShanghai200090China institute of Fisheries Engineering Chinese Academy of Fishery SciencesBeijing100141China Hunan Fisheries Science institute Changsha410153China jiangxi Fisheries Research institute Nanchang330039China Jiujiang academy of Fishery {2. Jiujiang332000China School of Life sciences Nanchang UniversityNanchang330031China Qinghai Provincial Fishery Technology Extension center Xining810012China Yunnan academy of Fishery sciences Kunming650111China institute of Hydroecology Ministry of Water Resources and Chinese Academy of SciencesWuhan430079China Fisheries institute Sichuan Academy of Agricultural SciencesChengdu611731China School of Life sciences Neijiang Normal UniversityNeijiang641100China School of Life sciences Southwest UniversityChongqing400715China Chongqing Fishery sciences Research institute Chongqing401120China Guizhou Fisheries Research institute Guiyang550025China College of Fisheries Huazhong Agricultural UniversityWuhan430072China Hubei Fisheries Science Research institute Wuhan430070China Shaanxi Fisheries Research institute Xi’an710086China Innovation academy for Precision Measurement Science and Technology Chinese Academy of SciencesWuhan430077China Nanjing institute of Geography and Limnology Chinese Academy of SciencesNanjing210008China Central South Inventory and Planning institute of State Forestry and Grassland Administration Changsha410014China

The yangtze River is the mother river of *** promote the aquatic ecosystem protection of the great river,the Project of yangtze Fisheries Resources and {2. Investigation(2.17-2.2.)supported by the Ministry of Agriculture and Rural Affairs,*** carried out by 2. institutes and universities that located in the yangtze River basin surveys the status of(1)fish species composition and spatial distribution,(2.current fish abundance,(3)endangered fishes,(4)yangtze finless porpoise,(5)aquatic eco-{2.s,(6)water-level fluctuation areas,(7)capture fisheries and recreational fisheries of the yangtze River mainstream and 10 of its main tributaries,including Yalong River,Heng River,Min River(including Dadu River),Chishui River,Tuo River,Jialing River,Wu River,Han River,Dongting Lake and Poyang *** results showed that there were 443 fish species(belonging to 163 genus,37 families,and 18 orders)before 2.17,but only 32. fish species(including 15 new recorded exotic species)were recorded in the project of *** them,Cyprinus carpio,Carassius auratus,Hypophthalmichthys molitrix,Pelteobagrus fulvidraco,Coilia brachygnathus,Silurus asotus,Saurogobio dabryi,Ctenopharyngodon idellus,Pelteobagrus nitidus,Hemiculter leucisculus,Siniperca chuatsi,Coreius heterodon,Culter alburnus,Parabramis pekinensis,and Aristichthys nobilis were the dominant species across the whole yangtze River *** is estimated that there were 886 million individuals weighing 12..8 million kg,merely equivalent to 2..3%of the resources in 1950s,30.9%of the resources in 1960s,or 58.7%of the resources in *** the new list of protected fishes that recorded in the yangtze River system,only 15 of 2. were collected in this project of *** gladius has been affirmed to be Extinct by international Union for Conservation of Nature(IUCN).The wild individuals of Tenualosa reevesii and Luciobrama macrocephalus have disappeared for many years and maybe have been extinct

关键词： Fishes yangtze finless porpoise Resources Aquatic ecosystem Fisheries Background investigation yangtze river system

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Altered intrinsic functional connectivity of the primary visual cortex in youth patients with comitant exotropia: a resting state fMRI study

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international Journal of Ophthalmology(English edition) 2018年第4期11卷 668-673页

作者： Pei-Wen zhu Xin Huang Lei Ye Nan jiang Yu-Lin Zhong Qing Yuan fu-Qing {2. Yi Shao Department of Ophthalmology the First Affiliated Hospital of Nanchang University Eye center Renmin Hospital of Wuhan University Wuhan University Department of Radiology the First Affiliated Hospital of Nanchang University

AIM： To evaluate the differences in the functional connectivity（FC） of the primary visual cortex（V1） between the youth comitant exotropia（CE） patients and health subjects using resting functional magnetic resonance imaging（f MRI） ***： Totally, 32.CEs（2. males and 7 females） and 32.healthy control subjects（HCs）（2. males and 7 females） were enrolled in the study and underwent the MRI scanning. Two-sample t-test was used to examine differences in FC maps between the CE patients and HCs. RESULTS： The CE patients showed significantly less FC between the left brodmann area（BA17） and left lingual gyrus/cerebellum posterior lobe, right middle occipital gyrus, left precentral gyrus/postcentral gyrus and right inferior parietal lobule/postcentral gyrus. Meanwhile, CE patients showed significantly less FC between right BA17 and right middle occipital gyrus（BA19, 37）.CONCLUSION： Our findings show that CE involves abnormal FC in primary visual cortex in many regions, which may underlie the pathologic mechanism of impaired fusion and stereoscopic vision in CEs.

关键词： comitant exotropia functional connectivity primary visual cortex spontaneous activity

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Causes of the Intraseasonal SST Variability in the Tropical Indian Ocean

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atmospheric and Oceanic Science Letters 2008年第1期1卷 18-23页

作者： Tim Li Francis Tam Xiouhua fu zhou Tian-Jun zhu Wei-Jun IPRC and Department of Meteorology University of Hawaii at Manoa Honolulu Hawaii USA institute of atmospheric {2. Chinese Academy of Sciences Beijing 100029 China Joint climate institute of CMA ＆ NUIST Nanjing University of Information Science ＆ Technology Nanjing 210044 China

Satellite observations reveal a much stronger intraseasonal sea surface temperature （SST） variability in the southern Indian Ocean along 5-10°S in boreal winter than in boreal summer. The cause of this seasonal dependence is studied using a 2.1/2.layer ocean model forced by ERA-40 reanalysis products during 1987-2.01. The simulated winter-summer asymmetry of the SST variability is consistent with the observed. A mixed-layer heat budget is analyzed. Mean surface westerlies along the ITCZ （5-10°S） in December-January-February （DJF） leads to an increased （decreased） evaporation in the westerly （easterly） phase of the intraseasonal oscillation （ISO）, during which convection is also enhanced （suppressed）. Thus the anomalous shortwave radiation, latent heat flux and entrainment effects are all in phase and produce strong SST signals. During June-July-August （JJA）, mean easterlies prevail south of the equator. Anomalies of the shortwave radiation tend to be out of phase to those of the latent heat flux and ocean entrainment. This mutual cancellation leads to a weak SST response in boreal summer. The resultant SST tendency is further diminished by a deeper mixed layer in JJA compared to that in DJF. The strong intraseasonal SST response in boreal winter may exert a delayed feedback to the subsequent opposite phase of ISO, implying a two-way air-sea interaction scenario on the intraseasonal timescale.

关键词： SST ISO shortwave radiation latent heatflux ocean entrainment

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STCF conceptual design report (Volume 1): physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.L.He Z.B.He Z.X.Heng B.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.jiang J.jiang S.Z.jiang J.B.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin B.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker institute of Nuclear physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central china Normal University Wuhan 430079China Central South University Changsha 410083China china University of Geosciences Wuhan 430074China china University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy physics center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China institute of Advanced Science Facilities Shenzhen 518107China institute of High Energy physics Chinese Academy of SciencesBeijing 100049China institute of Modern physics Chinese Academy of SciencesLanzhou 730000China institute of physics Academia SinicaTaipeiTaiwan 11529China institute of Theoretical physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the chinese particle physics *** is designed to operate in a {2.-of-mass energy range from 2.to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2.·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in china is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen fuqing Chen fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research institute Co. LtdBeijing Beijing institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker institute of Nuclear physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering {2. MianyangSichuan china building materials academy Beijing china center of Advanced Science and Technology Beijing china institute of Atomic Energy Beijing china Jiliang University HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china University of Geosciences Beijing china University of Geosciences WuhanHubei china University of Mining and Technology XuzhouJiangsu china West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint institute for Nuclear Research(DLNP JINR) Dubna East china University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2.s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2.15)and the Conceptual Design Report(CDR,2.18),comprehensively detailing the machine's la{2.t,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2.2.-2.2.,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2.30s.

关键词： initiated exceeding precise

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Transcriptomic characteristics and impaired immune function of patients who retest positive for SARS-CoV-2.RNA

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Journal of Molecular Cell Biology 2021年第10期13卷 748-759页

作者： Dongyao Wang Dong Wang Min Huang Xiaohu Zheng Yiqing Shen Binqing fu Hong Zhao Xianxiang Chen Peng Peng Qi zhu Yonggang zhou Jinghe Zhang Zhigang Tian Wuxiang Guan Guiqiang Wang Haiming Wei Division of Life sciences and Medicine Department of HematologyThe First Affiliated Hospital of University of Science and Technology of ChinaUniversity of Science and Technology of ChinaHefei 230001China institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease School of Basic Medicine and Medical CenterUniversity of Science and Technology of ChinaHefei 230001China Hefei National Laboratory for Physical sciences at Microscale University of Science and Technology of ChinaHefei 230001China Department of Laboratory Medicine Tongji HospitalTongji Medical CollegeHuaZhong University of Science and TechnologyWuhan 430030China Department of Infectious Diseases Peking University First HospitalBeijing 100034China Department of Tuberculosis Wuhan Pulmonary HospitalWuhan 430030China center for Emerging Infectious Diseases Wuhan Institute of VirologyChinese Academy of SciencesWuhan 430071China Peking University international Hospital Beijing 100034China

Coronavirus disease 2.19(COVID-19),caused by severe acute respiratory syndrome coronavirus 2.SARS-CoV-2.infection,has become a global public health *** patients who have recovered from COVID-19 subsequently test positive again for SARS-CoV-2.RNA after discharge from *** such retest-positive(RTP)patients become infected again is not *** this study,30 RTP patients,2. convalescent patients,and 2. healthy controls were enrolled for the analysis of immunological characteristics of their peripheral blood mononuclear *** found that absolute numbers of CD4^(+)T cells,CD8^(+)T cells,and natural killer cells were not substantially decreased in RTP patients,but the expression of activation markers on these cells was significantly *** percentage of granzyme B-producing T cells was also lower in RTP patients than in convalescent *** transcriptome sequencing,we demonstrated that high expression of inhibitor of differentiation 1(ID1)and low expression of interferon-induced transmembrane protein 10(IFITM10)were associated with insufficient activation of immune cells and the occurrence of *** findings provide insight into the impaired immune function associated with COVID-19 and the pathogenesis of RTP,which may contribute to a better understanding of the mechanisms underlying RTP.

关键词： COVID-19 CD8f T cells NK cells RTP patients immune function

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Screening for amblyopia among grade-1 students in primary school with uncorrected vision and stereopsis test in central china

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chinese Medical Journal 2013年第5期126卷 903-908页

作者： fu Jing LI Shi-ming LI Jin-ling LI Si-yuan LIU Luo-ru WANG yang LI He zhu Bi-dan JI Ya-{2. yanG {2. LI Lei CHEN Wei WANG Ning-li Beijing Tongren tye center Beijing Tongren Hospital CapitalMedical University Beijing Ophthalmology and Visual ScienceKey Laboratory Beijing 100730 China Anyang Eye Hospital Anyang Henan 455000 China Department of Ophthalmology Second Hospital Affiliated toHarbin Medical University Harbin Heilongjiang 150001 China

Background Screening for amblyopia at earliest is important for early treatment and better prognosis. This study aimed to evaluate the validity of uncorrected distant and near visual acuity （VA） and stereoacuity for screening amblyopia in grade-1 students in primary school in central china. Methods By stratified cluster sampling, 3.1. grade-1 students from 11 An{2.g primary schools were selected for the study. All the participants underwent uncorrected distant and near VA, stereopsis test, cycloplegic refraction, best corrected VA （BCVA）, cover test, and ocular movement examination. VA was measured with a logarithm of the minimum angle of resolution （IogMAR） chart. Stereoacuity was measured with the Lang II stereo card and TNO test. Amblyopia was defined as the BCVA less than or equal to 0.1 IogMAR units of any eye in the absence of significant pathological abnormalities. The sensitivity, specificity, and 3ositive and negative predictive value of uncorrected VA and stereoacuity for amblyopia were analyzed. Results Out of the 3.1. eligible students 2.93 （92.96%） completed the examinations. The average age of the students was （7.10±0.41） years. Screened by distant VA with low cutoff （IogMAR 0.1）, high cutoff （IogMAR 0.0）, and near VA （IogMAR 0.0）, 31.64%, 73.1.%, and 50.2.% students were abnormal, respectively. Screened by stereopsis test, only 4.69% students were abnormal. Diagnosed by a senior pediatric ophthalmologist, 61 students had amblyopia. The sensitivities of distant VA with low/high cutoff and near VA were 92.31%, 100%, and 80.77%, respectively, whereas that of stereoacuity by TNO test was 15.38%. Simultaneous testing of either two of the three tests improved the sensitivity. Conclusions Distant VA test of high cutoff alone displays a high sensitivity but a low specificity. Simultaneous testing of distant VA of low cutoff and stereoacuity is a better choice to balance between sensitivity and specificity.

关键词： amblyopia vision screening visual acuity steropsis test

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