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Major Problems Related with Operation of Catalytic Reforming Units and Countermeasures

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China Petroleum Processing & Petrochemical Technology 2006年第2期8卷 1-13页

作者： zhou jianhua Petroleum Refining Division Sinopec Corp. Beijing 100029

Currently the catalytic reforming units are playing an increasingly important role for gasoline quality upgrading, increased production of high add-value aromatic compounds and supply of cheap hydrogen resources. The high proportion of FCC gasoline in China＇s automotive gasoline pool has led to a quite significant gap in gasoline quality as compared to the demand of World Fuel Charter and even to the new Chinese standards for unleaded automotive gasoline. According to the statistical data, the ratio of FCC naphtha in the gasoline pool is 35% in the US and 27% in EU, whereas that number is 75% in China＇s gasoline pool. The share of reformate and other high-quality gasoline components in the gasoline pool is 65% in the US and 73% in EU, whereas that number is merely 14% in China＇s gasoline pool along with a definite share of low-octane （straight-run） gasoline.

关键词：催化重整汽油产品质量流化床催化裂化辛烷值石脑油

Orbit determination and prediction for Beidou GEO satellites at the time of the spring/autumn equinox

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Science China(Physics,Mechanics & Astronomy) 2015年第8期58卷 86-94页

作者： LI XiaoJie zhou jianhua HU XiaoGong LIU Li GUO Rui zhou ShanShi Beijing Satellite Navigation Center Shanghai Key Laboratory of Space Navigation and Position Techniques Shanghai Astronomical Observatory Chinese Academy of Sciences

Geostationary(GEO) satellites form an indispensable component of the constellation of Beidou navigation system(BDS). The ephemerides, or predicted orbits of these GEO satellites(GEOs), are broadcast to positioning, navigation, and timing users. User equivalent ranging error(UERE) based on broadcast message is better than 1.5 m(root formal errors: RMS) for GEO satellites. However, monitoring of UERE indicates that the orbital prediction precision is significantly degraded when the Sun is close to the Earth's equatorial plane(or near spring or autumn Equinox). Error source analysis shows that the complicated solar radiation pressure on satellite buses and the simple box-wing model maybe the major contributor to the deterioration of orbital precision. With the aid of BDS' two-way frequency and time transfer between the GEOs and Beidou time(BDT, that is maintained at the master control station), we propose a new orbit determination strategy, namely three-step approach of the multi-satellite precise orbit determination(MPOD). Pseudo-range(carrier phase) data are transformed to geometric range(biased geometric range) data without clock offsets; and reasonable empirical acceleration parameters are estimated along with orbital elements to account for the error in solar radiation pressure modeling. Experiments with Beidou data show that using the proposed approach, the GEOs' UERE when near the autumn Equinox of 2012 can be improved to 1.3 m from 2.5 m(RMS), and the probability of user equivalent range error(UERE)<2.0 m can be improved from 50% to above 85%.

关键词： Beidou system (BDS) Beidou time (BDT) geostationary (GEO) satellite spring equinox/autumn equinox solar radia-tion pressure time synchronization user equivalent ranging error

Quantum coherent control of ultrashort laser pulses

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Chinese Science Bulletin 2008年第5期53卷 652-658页

作者： zhou JianYing ZENG jianhua LI dunTao State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen University Guangzhou 510275 China

The effective photonic control is one of the key issues in photo-physics. Significant advancement in photonic crystals, quantum optics, ultrafast optics as well as micro-nano-optics gives rise to new op-portunities to manipulate the emission and propagation in optical fields, leading to a number of new and interesting discoveries, e.g., ultrashort light pulse storage and efficient energy conversion. This paper reviews the latest research progress in storage, release and energy conversion for ultrashort laser pulses in periodical arrays of absorbing medium. Techniques to fabricate such devices are also presented.

关键词：超短激光脉冲光学晶体孤波半导体量子阱全息印刷术量子相干控制

Plasmonic biosensing based on non-noble-metal materials

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Chinese Chemical Letters 2018年第1期29卷 54-60页

作者： jianhua zhou Yangyang Wang Li Zhang Xuemeng Li Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province Department of Biomedical Engineering School of Engineering Sun Yat-sen University

Plasmonic nanostructures can confine light through localized surface plasmon resonance （LSPR）, thereby enabling highly sensitive, label-free, and real-time physical and chemical sensing. Nowadays, the LSPR biosensing based on noble metal is still restricted in research laboratories, due to the limitations of their intrinsic properties, high prime price, and high process cost. Researchers thereby have paid attention to the non-noble metals and semiconductor materials in recent years. This review focuses on the research progress of non-noble-metal materials with nanostructures for plasmonic biosensing. Firstly, the physical and sensing principles of LSPR sensors are briefly introduced. Then, non-noble-metal materials, such as copper, aluminum, semiconductor, graphene and other materials, for plasmonic sensing are categorized and presented. Finally, a rational discussion about the future prospective of novel materials for plasmonic sensing is given.

关键词： Plasmonic biosensingLocalized surface plasmon resonanceNon-noble-metal nanomaterialCopperAluminumSemiconductorGraphene

Growth and Characterization of High-quality LiAlO2 Single Crystal

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Journal of Materials Science & Technology 2008年第2期24卷 145-148页

作者： Taohua HUANG Shengming zhou Hao TENG Hui LIN Jun ZOU jianhua zhou Jun WANG Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China Graduate School of Chinese Academy of Sciences Beijing 100039 China

γ-LiAlO2 single crystal is a promising substrate for GaN heteroepitaxy. In this paper, we present the growth of large-sized LiAlO2 crystal by modified Czochralski method. The crystal quality was characterized by high-resolution X-ray diffraction and chemical etching. The results show that the as-grown crystal has perfect quality with the full width at half maximum （FWHM） of 17.7-22.6 arcsec and etch pits density of （0.3- 2.2）×10^4 cm^-2 throughout the crystal boule. The bottom of the crystal boule shows the best quality. The optical transmission spectra from UV to IR exhibits that the crystal is transparent from 0.2 to 5.5μm and becomes completely absorbing around 6.7μm wavelength, The optical absorption edge in near UV region is about 191 nm.

关键词： γ-LiAlO2 crystal Czochralski method Chemical etching Transmission spectra

Uncertainty Optimization Design of a Vehicle Body Structure Considering Random Deviations

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Automotive Innovation 2018年第4期1卷 342-351页

作者： jianhua zhou Fengchong Lan Jiqing Chen Fanjie Lai School of Mechanical and Automotive Engineering South China University of TechnologyGuangzhou 510640China Guangdong Provincial Key Laboratory of Automotive Engineering Guangzhou 510640China

In vehicle body manufacturing,there are small differences between the actual value and design value of,for example,plate thickness and material *** is caused by the processing technology,environment and other uncertain ***,the performance of the vehicle body processed according to the deterministic optimization solution *** fluctuations may make structural performance fail to meet the design ***,in this study,an optimization design is executed with 6σrobustness criteria and a Monte Carlo simulation single-loop optimization strategy based on the radial basis function neural network approximate model considering deviations in plate thickness,elastic modulus,and welding spot diameter,which is called the uncertainty optimization design *** an example,considering the bending stiffness,torsion stiffness,and first-order frequency as constraints,the method is applied to the lightweight design of a car body structure,and the reliability of deterministic optimization design and uncertainty optimization design is *** results demonstrate that the uncertainty optimization design solution is effective and feasible without lowering the static stiffness and modal performance,and the weight is reduced.

关键词： Body structure Lightweight Approximate models 6σrobustness criteria MCS single-loop optimization strategy

Influence of the GEO satellite orbit error fluctuation correction on the BDS WADS zone correction

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Satellite Navigation 2020年第1期1卷 198-205页

作者： Binghao Wang jianhua zhou Bin Wang Dianwei Cong Hui Zhang Beijing Navigation Center Beijing 100094China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Information Engineering University Zhengzhou 450052China National Defense University Joint Operations College Shijiazhuang 050001China

Decimeter-level service is provided by the BeiDou satellite navigation system wide area differential service(BDS WADS)for users who collect carrier phase ***,the fluctuations in Geostationary Earth Orbit(GEO)satellite orbit errors reduce the spatial correlation of orbit *** fluctuations not only decrease the accuracy and stability of zone correction service provided by BDS WADS,but also shorten its effective *** this paper,we proposed an algorithm to weaken the influence of GEO satellite orbit error fluctuations and verified the method using data from eight sparsely distributed *** results show that orbit errors can be stabilized using orbit fluctuation corrections,and the positioning precision and stability of the BDS WADS can be improved *** normal circumstances,the horizontal and vertical positioning accuracy of users within 1000 km from the center of the zone can reach 0.19 m and 0.34 ***,the effective range is *** positioning performance within 1800 km could reach 0.24 m and 0.38 m for the horizontal and vertical components,respectively.

关键词： Wide area differential service Decimeter-level service Zone correction GEO orbit error Effective range

Clinical characterization and diagnosis of cystic fibrosis throughexome sequencing in Chinese infants with Bartter-syndrome-like hypokalemia alkalosis

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Frontiers of Medicine 2018年第5期12卷 550-558页

作者： Liru Qiu Fengjie Yang Yonghua He Huiqing Yuan jianhua zhou Department of Pediatrics Tongji Hospital Tongji Medical College Huazhong University of Science & Technology Wuhan 430030 China

Cystic fibrosis (CF) is a fatal autosomal-recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. CF is characterized by recurrent pulmonary infection with obstructive pulmonary disease. CF is common in the Caucasian population but is rare in the Chinese population. The symptoms of early-stage CF are often untypical and may sometimes manifest as Bartter syndrome (BS)-like hypokalemic alkalosis. Therefore, the ability of doctors to differentiate CF from BS-like hypokalemic alkalosis in Chinese infants is a great challenge in the timely and accurate diagnosis of CF. In China, sporadic CF has not been diagnosed in children younger than three years of age to date. Three infants, who were initially admitted to our hospital over the period of June 2013 to September 2014 with BS-like hypokalemic alkalosis, were diagnosed with CF through exome sequencing and sweat chloride measurement. The compound heterozygous mutations of the CFTR gene were detected in two infants, and a homozygous missense mutation was found in one infant. Among the six identified mutations, two are novel point mutations (c.1526G > C and c.3062C > T) that are possibly pathogenic. The three infants are the youngest Chinese patients to have been diagnosed with sporadic CF at a very early stage. Follow-up examination showed that all of the cases remained symptom-free after early intervention, indicating the potential benefit of very early diagnosis and timely intervention in children with CF. Our results demonstrate the necessity of distinguishing CF from BS in Chinese infants with hypokalemic alkalosis and the significant diagnostic value of powerful exome sequencing for rare genetic diseases. Furthermore, our findings expand the CFTR mutation spectrum associated with CF.

关键词： CFTR gene cystic fibrosis diagnosis hypokalemic alkalosis infants mutations pseudo-Bartter syndrome

Anti-cd TCR antibody-expanded cd T cells:a better choice for the adoptive immunotherapy of lymphoid malignancies

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Cellular & Molecular Immunology 2012年第1期9卷 34-44页

作者： jianhua zhou Ning Kang Lianxian Cui Denian Ba Wei He Department of Immunology Institute of Basic Medical SciencesChinese Academy of Medical Sciences and School of Basic MedicinePeking Union Medical CollegeNational Key Laboratory of Medical Molecular BiologyBeijingChina

Cell-based immunotherapy for lymphoid malignancies has gained increasing attention as patients develop resistance to conventional *** T cells,which have major histocompatibility complex(MHC)-unrestricted lytic activity,have become a promising candidate population for adoptive cell transfer *** previously established a stable condition for expanding cd T cells by using anti-cd T-cell receptor(TCR)*** this study,we found that adoptive transfer of the expanded cd T cells to Daudi lymphoma-bearing nude mice significantly prolonged the survival time of the mice and improved their living *** further investigated the characteristics of these antibody-expanded cd T cells compared to the more commonly used phosphoantigen-expanded cd T cells and evaluated the feasibility of employing them in the treatment of lymphoid *** but sustained proliferation of human peripheral blood cd T cells was observed upon stimulation with anti-cd TCR *** to phosphoantigen-stimulated cd T cells,the antibody-expanded cells manifested similar functional phenotypes and cytotoxic activity towards lymphoma cell *** is noteworthy that the anti-cd TCR antibody could expand both the Vd1 and Vd2 subsets of cd T *** in vitro-expanded Vd1 T cells displayed comparable tumour cell-killing activity to Vd2 T ***,owing to higher C–C chemokine receptor 4(CCR4)and CCR8 expression,the Vd1 T cells were more prone to infiltrate CCL17-or CCL22-expressing lymphomas than the Vd2 T *** the peripheral blood cd T cells from lymphoma patients further confirmed that the anti-cd TCR antibody-expanded cd T cells could be a more efficacious choice for the treatment of lymphoid malignancies than phosphoantigen-expanded cd T cells.

关键词： adoptive cell therapy anti-cd TCR antibody cd T cells lymphoid malignancies Vd1 subset