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Laser Cooling Using Anti-Stokes Fluorescence in Yb^(3+)-Doped Fluorozirconate Glasses

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Wuhan University Journal of Natural Sciences 2002年第2期7卷 177-181页

作者： Xu Tian-ming Li cheng-fang Zhou Xiao zhong Jia-cheng School of Physics and Technology Wuhan UniversityWuhan 430072HubeiChina Infrared Material Institute Wuhan UniversityWuhan 430072HubeiChina

The fluorozirconate glasses ZBLANP( ZrF\-4-BaF\-2-LaF\-3-AlF\-3-NaF-PbF\-2) doped with different Yb\+ 3+ concentration were prepared. The Raman spectra and absorption spectra are measured to substantiate the existence of phonon-assisted emission. After analyzing the normalized absorption spectra of samples with different Yb\+ 3+-doped concentration, we calculated the maximum cooling effect in the 3 wt% Yb\+ 3+-doped sample pumped at 1 012.5 nm. The corresponding cooling capability is about -4.09 ℃/W and the cooling efficiency reaches 1.76%.

关键词： anti-Stokes fluorescence Yb^(3+)-doped ZBLANP glass cooling efficiency

Recent progress of on-resin cyclization for the synthesis of clycopeptidomimetics

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Chinese Chemical Letters 2016年第12期27卷 1731-1739页

作者： Zhi-Meng Wu Shao-zhong Liu Xiao-zhong cheng Wen-Zhang Ding Tao Zhu Bing Chen The Key Laboratory of Carbohydrate Chemistry & Biotechnology Ministry of Education School of Biotechnology Jiangnan University

Cyclopeptidomimetics are class of cyclopeptides with unnatural linkage. They usually displayed unique constrained structure, enhanced proteolytic stability, and other drug-like character; and have been widely used in medicinal chemistry. Therefore, development of efficient strategies for the synthesis of cyclopeptidomimetics has received many attentions. On-resin cyclization strategy is one of the effective approaches developed to overcome the competing side reaction such as oligomerization and cyclooligomers occurred in solution cyclization. This approach took advantage of the ＂pseudo-dilution＂ effect to avoid these undesired by-products and greatly simplified the downstream product purification process. This review summarized the recent on-resin peptide cyclization strategies for the synthesis of cvclooeotidomimetics.

关键词： Cyclopeptidomimetics On-resin Cyclization Synthesis

A progressive compression model of thoracic spinal cord injury in mice： function assessment and pathological changes in spinal cord

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Neural Regeneration Research 2017年第8期12卷 1365-1374页

作者： Guo-dong Sun Yan Chen Zhi-gang Zhou Shu-xian Yang cheng zhong Zhi-zhong Li Department of Orthopedics First Affiliated HospitalJinan UniversityGuangzhouGuangdong ProvinceChina Biomedical Translational Research Institute and Guangdong Province Key Laboratory of Molecular Immunology and Antibody Engineering Jinan UniversityGuangzhouGuangdong ProvinceChina Department Of Traumatology and-Plastic Surgery The Affiliated Jiangmen Traditional Chinese Medicine Hospital of Jinan UniversityJiangmenGuangdong ProvinceChina Department of Orthopedics Heyuan People's Hospital(Heyuan Affiliated Hospital of Jinan University)HeyuanGuangdong ProvinceChina

Non-traumatic injury accounts for approximately half of clinical spinal cord injury, including chronic spinal cord compression. However, previous rodent spinal cord compression models are mainly designed for rats, few are available for mice. Our aim is to develop a thoracic progressive compression mice model of spinal cord injury. In this study, adult wild-type C57BL/6 mice were divided into two groups： in the surgery group, a screw was inserted at T9 lamina to compress the spinal cord, and the compression was increased by turning it further into the canal（0.2 mm） post-surgery every 2 weeks up to 8 weeks. In the control group, a hole was drilled into the lamina without inserting a screw. The results showed that Basso Mouse Scale scores were lower and gait worsened. In addition, the degree of hindlimb dysfunction in mice was consistent with the degree of spinal cord compression. The number of motor neurons in the anterior horn of the spinal cord was reduced in all groups of mice, whereas astrocytes and microglia were gradually activated and proliferated. In conclusion, this progressive compression of thoracic spinal cord injury in mice is a preferable model for chronic progressive spinal cord compression injury.

关键词： nerve regeneration progressive spinal cord compression injury pathological changes Basso Mouse Scale scores gait motor evokedpotentials astrocytes microglia motor neurons hindlimb dysfunction neural regeneration

基于化学发光免疫技术检测念珠菌IgG抗体方法的建立与性能评估

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中国免疫学杂志 2024年第2期40卷 389-394页

作者：李静静王雪琦孙娅顺赵思琪刘春龙钟成天津科技大学生物工程学院天津300457 天津市侵袭性真菌病精准诊断技术企业重点实验室天津300467

目的:基于化学发光免疫技术建立一种即时检测念珠菌甘露聚糖IgG抗体的方法。方法:依据间接法原理建立念珠菌甘露聚糖IgG抗体检测体系,并参照美国临床试验室标准化协会(CLSI)批准指南进行分析性能评估。结果:生物素标记念珠菌甘露聚糖抗... 详细信息

目的:基于化学发光免疫技术建立一种即时检测念珠菌甘露聚糖IgG抗体的方法。方法:依据间接法原理建立念珠菌甘露聚糖IgG抗体检测体系,并参照美国临床试验室标准化协会(CLSI)批准指南进行分析性能评估。结果:生物素标记念珠菌甘露聚糖抗原与碱性磷酸酶标记抗人IgG抗体工作液浓度均为1μg/ml;检测方法空白限为5.20 AU/ml;检出限为5.50 AU/ml;试剂精密度与重复性变异系数(CV)均<10%;检测方法与常见特异性抗体无交叉反应;血红蛋白、三酰甘油及胆红素对临床样本均无显著影响;检测方法与ELISA法总体符合率为90%,Kappa值=0.80,回归分析与偏差分析结果均表明两种方法有较强一致性(R2=0.9898)。结论:本研究所建立检测体系性能均符合临床辅助诊断技术相关要求,适用于血清样本中念珠菌甘露聚糖IgG抗体的快速检测。

关键词：念珠菌IgG抗体化学发光免疫技术性能分析

Microstructures and Optical Properties of Sol-Gel Derived TiO_2 Anatase Thin Films

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Wuhan University Journal of Natural Sciences 1999年第2期4卷 48-51页

作者： Liu, zhong-chi Zou, Hua-min zhong, Jia-cheng Wang, Da-hai Wuhan Univ Wuhan China

TiO 2 anatase thin films on quartz substrates were prepared with sol gel method. The dry gel films, made by spin coating 10 times, were calcined at various temperatures. From X ray diffraction analyses, it is found that the anatase to rutile phase transformation temperature of the films is higher than 850 ℃, the films are preferentially oriented on (0 0 1) plane, i.e. c axis oriented. The thickness, refractive indexes, absorption coefficients and extinction coefficients of the films were determined from UV Vis transmission spectra of the films using a UV Vis spectrophotometer. The thickness of the films is about 570 nm. The refractive indexes, absorption coefficients and the extinction coefficients of the present films are larger than the values of anatase films prepared by sputtering. This indicates that the films made with sol gel method are very dense.

关键词： titanium dioxide anatase thin film

Signaling Product Quality by Price

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Frontiers of Economics in China-Selected Publications from Chinese Universities 2012年第3期7卷 363-372页

作者： Shane Parendo cheng-zhong Qin Department of Economics University of California Santa Barbara CA 93106 USA

This paper analyzes the role of price as a signal of the quality of a monopoly firm＇s new product. The quality of the goods is drawn from a continuum and is unknown to consumers. We establish a unique separating equilibrium using equilibrium characterization results for signaling games. The equilibrium price monotonically increases with quality levels and exceeds the complete-information monopoly price for all quality levels but the lowest one. However, the upward distortion decreases as the proportion of pre-informed consumers increases. These results extend both the signaling role of price and characteristics of the separating equilibrium as established in Bagwell and Riordan （1991）.

关键词： separating equilibrium price distortion signaling game

High yield synthesis of cyclic analogues of antibacterial peptides P-113 by Sortase A-mediated ligation and their conformation studies

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Chinese Chemical Letters 2017年第3期28卷 553-557页

作者： Zhi-Meng Wu Shao-zhong Liu Xiao-zhong cheng Xin-Rui Zhao Hao-Fei Hong The Key Laboratory of Carbohydrate Chemistry 8' Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi 214122 China

P-113 is a fragment of natural occurring peptide Histatin 5 found in human saliva. This peptide exhibited broad spectrum of antibacterial and antifungal biological activities. In this study, bifunctional P-113 peptides 2–5 were designed as Sortase A substrates and synthesized by solid support peptide synthesis,where the N-terminus were equipped with glycine and its analogues, and C-terminus were extended with LPETGGS, respectively. Under Sortase A catalyzed condition, head to tail cyclization products 7–10were afforded in yields from 76% to 93%. The conformation insights of linear peptides 2–5 and cyclic analogues 7–10 in aqueous buffers and in trifluroethanol（TFE） analyzed by circular dichroism（CD）suggested that a-helix structures were produced progressively in hydrophobic environment independent of the cyclization, which displayed the similar behavior as parent peptide P-113.

关键词： Antibacterial peptide P-113 Cyclization Sortase A-mediated ligation Conformation Circular dichroism

Electronic and topological properties of kagome lattice LaV3Si2

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钨科技(英文) 2023年第3期5卷 317-324页

作者： Xue-Jiao Chen Bing-Wen Zhang Dong Han Zhi-cheng zhong CAS Key Laboratory of Magnetic Materials Devices and Zhejiang Province Key Laboratory of Magnetic Materials and Application TechnologyNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Fujian Key Laboratory of Functional Marine Sensing Materials Center for Advanced Marine Materials and Smart SensorsCollege of Material and Chemical EngineeringMinjiang UniversityFuzhou 350108China Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of SciencesChangchun 130033China China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Topological kagome lattice at the frontier of fundamental physics plays a key role in non-trivial topological quantum ***,we predict and investigate kagome lattice rare-earth vanadium-based quantum material LaV3Si2using density functional theory *** phonon spectrum and crystal transformation show stability of this material,which may be grown by experimental *** fermions,flat bands,and van Hove points as some basic features are presented in band structure and surface ***,symmetry-based compatibility relations support enforced semi-metal for occupied electron numbers with strong Berry *** results suggest that rare-earth vanadium-based RV3Si2can be treated as a new family kagome lattice.

关键词： Vanadium Kagome lattice Rare earth Electronic Dirac points

Market Equilibrium Based on Cloud-edge Collaboration

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 96-104页

作者： Tong cheng Haiwang zhong Qing Xia the State Key Laboratory of Power Systems the Department of Electrical EngineeringTsinghua UniversityBeijing 100084China

Market participants can only bid with lagged information disclosure under the existing market mechanism,which can lead to information asymmetry and irrational market behavior,thus influencing market *** promote rational bidding behavior of market participants and improve market efficiency,a novel electricity market mechanism based on cloudedge collaboration is proposed in this *** market information,called residual demand curve,is published to market participants in real-time on the cloud side,while participants on the edge side are allowed to adjust their bids according to the information disclosure prior to closure *** proposed mechanism can encourage rational bids in an incentive-compatible way through the process of dynamic equilibrium while protecting participants’*** paper further formulates the mathematical model of market equilibrium to simulate the process of each market participant’s strategic bidding behavior towards equilibrium.A case study based on the IEEE 30-bus system shows the proposed market mechanism can effectively guide bidding behavior of market participants,while condensing exchanged information and protecting privacy of participants.

关键词： Cloud-edge collaboration market mechanism residual demand curve strategic bidding