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Association of preoperative antiviral treatment with incidences of post-hepatectomy liver failure in hepatitis B virus-related hepatocellular carcinoma

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2106-2118页

作者： Xiao Wang zhao-yi lin You Zhou Qin Zhong Zong-Ren Li Xi-Xiang lin Ming-Gen Hu Kun-Lun He Medical Big Data Research Center Chinese PLA General HospitalBeijing 100853China Medical School of Chinese PLA Chinese PLA General HospitalBeijing 100853China Department of Hepatobiliary Surgery Chinese PLA 970th HospitalYantai 264001Shandong ProvinceChina Faculty of Hepato-Pancreato-Biliary Surgery The First Medical Center of Chinese PLA General HospitalBeijing 100853China School of Medicine Nankai UniversityTianjin 300071China

BACKGROUND Post-hepatectomy liver failure(PHLF)is a common consequence of radical partial hepatectomy in hepatocellular carcinoma(HCC).AIMS To investigate the relationship between preoperative antiviral therapy and PHLF,as well as assess the potential efficacy of hepatitis B virus(HBV)DNA level in predicting *** A retrospective study was performed involving 1301 HCC patients with HBV who underwent radical *** operating characteristic(ROC)analysis was used to assess the capacity of HBV DNA to predict PHLF and establish the optimal cutoff value for subsequent *** regression analyses were performed to assess the independent risk factors of *** increase in the area under the ROC curve,categorical net reclassification improvement(NRI),and integrated discrimination improvement(IDI)were used to quantify the efficacy of HBV DNA level for predicting *** P<0.05 was considered statistically *** Logistic regression analyses showed that preoperative antiviral therapy was independently associated with a reduced risk of PHLF(P<0.05).HBV DNA level with an optimal cutoff value of 269 IU/mL(P<0.001)was an independent risk factor of *** the reference models by adding the variable of HBV DNA level had an improvement in area under the curve,categorical NRI,and IDI,particularly for the fibrosis-4 model,with values of 0.729(95%CI:0.705-0.754),1.382(95%CI:1.341-1.423),and 0.112(95%CI:0.110-0.114),*** the above findings were statistically *** In summary,preoperative antiviral treatment can reduce the incidence of PHLF,whereas an increased preoperative HBV DNA level has a correlative relationship with an increased susceptibility to PHLF.

关键词： Hepatocellular carcinoma Hepatitis B virus Preoperative antiviral treatment Liver resection Post-hepatectomy liver failure

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Janus hydrogel/electrospun-membrane dressing enhancing wound healing in rats

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Biomedical Engineering Communications 2024年第2期3卷 17-25页

作者： Zi-Rui Zhu Jia-Na Huang Jin-Ze Li Hao Cao zhao-yi lin Yan Li School of Biomedical Engineering Shenzhen Campus of Sun Yat-sen UniversityShenzhen 518107China Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument Sun Yat-sen UniversityGuangzhou 510006China

Background:Excessive exudate secreted from chronic wounds often leads to overhydration and *** a variety of dressings are currently available in clinical applications,they frequently fail to provide multifunction to promote chronic wound *** dressings with a Janus structure,featuring distinct properties on each side,are potential to improve wound ***:Composite dressings with a Janus structure were fabricated,comprising freeze-dried polycaprolactone(PCL)electrospun membrane and alginate-based *** PCL fibrous membrane provided air permeability,while the hydrogel loaded with Deferoxamine,composed of alginate and poly(N-isopropylacrylamide)(PNIPAM),exhibited hygroscopic *** inclusion of PNIPAM imparted ***:The hydrogel(thickness of 2.778±0.082 mm)exhibited a robust adhesion to the fiber membrane(thickness of 0.261±0.041 mm).For ANDC(Alginate-PNIPAM hydrogel with Deferoxamine/PCL membrane)samples,the water vapor transmission rate(WVTR)was measured to be 3364.80±23.23 g∙m−2∙day−1 and the swelling ratio at 2 h was determined to be 1179±125%.The thermo-responsivity of ANDC samples manifested in an increased swelling rate,escalating from 797±189%at 37°C to 1132±147%at 4°*** elastic modulus was assessed for lyophilized and rehydrated ANDC *** theωof the rheometer rotor was decreased from 10 rad/s to 0.1 rad/s,the lyophilized dressing exhibited a decrease from 2.65±0.01 MPa to 1.80±0.90 MPa,while the rehydrated dressing demonstrated an increase from 133.65±55.68 Pa to 264.23±141.71 *** pro-healing properties of the dressings were evaluated using full-thickness skin defect model on SD rats,and a circular wound of diameter 10 mm healed completely by day ***:The dressings not only protected the wound and absorbed excess exudate,but also demonstrated nondestructive peelability upon cooling,providing a novel approach for accelerating wound healing and management.

关键词： Janus structure composite dressing wound healing

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创新驱动国家中心城市经济高质量发展研究——经济政策不确定性的“U”型调节效应

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技术经济与管理研究 2024年第4期 83-89页

作者：赵倚林尚娟史官清西安电子科技大学经济与管理学院陕西西安710126 百色学院马克思主义学院广西百色533000

选取国家中心城市2010—2020年面板数据,实证分析创新对经济高质量发展的作用机制,并分析经济政策不确定性作为调节变量对经济高质量发展以及对创新驱动转化效果的影响。结果表明:国家中心城市创新能够显著促进经济高质量发展;经济政策... 详细信息

选取国家中心城市2010—2020年面板数据,实证分析创新对经济高质量发展的作用机制,并分析经济政策不确定性作为调节变量对经济高质量发展以及对创新驱动转化效果的影响。结果表明:国家中心城市创新能够显著促进经济高质量发展;经济政策不确定性与经济高质量发展存在“U”型关系;经济政策不确定性在创新水平与经济高质量发展之间存在“U”型调节作用。区域异质性表明,东部地区创新驱动效果更佳,且对经济政策不确定性的敏感程度更强。据此,提出国家中心城市“因城施策、因时施策、因业施策”的组合发展策略体系。

关键词：国家中心城市创新发展经济政策不确定性经济高质量发展

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Substitution Effects on MgB2 Superconductivity

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Communications in Theoretical Physics 2008年第2期49卷 504-506页

作者： LIU Juan zhao Yuan yi lin Department of Physics Huazhong University of Science and Technology Wuhan 430074 China

With the help of supercell method, the first-principle calculations were performed for the study of doping crystal Mg1-xAlxB2 and Mg（B1-yCy）2. Analyzing the variations of the charge distribution and the partial densities of states, we found that the compounds with doping Al to MgB2 compound and/or replacing boron by carbon exhibit new covalent bond effects and unexpected electronic properties, related to superconductivity. The study of the density of states indicates that superconductivity decreases with the increase of Al fraction and carbon concentration. There exists a transition of superconductor to non-superconductor with the change of Al doping fraction. The substitution of boron by carbon results in the decrease of the transition temperature since the decrease of the electron concentration and the lattice constant. The theoretical predictions agree with experimental observations.

关键词： superconductivity first-principles calculations density of states

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血清胱抑素C、肌酐、尿素联合检测在糖尿病肾病诊断及肾功能损害预测中的价值

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医学信息 2024年第9期37卷 141-144页

作者：赵依琳汪蔚冯淑嘉溧阳市人民医院检验科

目的研究血清胱抑素C(Cys-C)、肌酐（Cr）、尿素（UREA）联合检测在糖尿病肾病（DN）诊断及肾功能损害预测中的应用价值。方法选取2021年1月-2023年3月溧阳市人民医院收治的50例DN患者设为DN组，另选取同期收治的50例单纯糖尿病患者设... 详细信息

目的研究血清胱抑素C(Cys-C)、肌酐（Cr）、尿素（UREA）联合检测在糖尿病肾病（DN）诊断及肾功能损害预测中的应用价值。方法选取2021年1月-2023年3月溧阳市人民医院收治的50例DN患者设为DN组，另选取同期收治的50例单纯糖尿病患者设为DM组，比较两组血清Cys-C、Cr、UREA水平及各项指标的阳性检出率，并分析Cys-C、Cr、UREA单独及联合检测对DN的诊断价值，另比较各项指标在不同肾损伤分级中的差异。结果 DN组血清Cys-C、Cr、UREA水平高于DM组（PⅣ期>Ⅲ期>Ⅱ期>Ⅰ期。结论血清Cys-C、Cr、UREA联合检测对DN具有较高诊断价值，在肾功能损害的预测评估中可发挥确切作用。

关键词：糖尿病肾病肾功能损害血清胱抑素C 肌酐尿素

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冻融和盐作用对糯米粉的结构和糊化特性的影响

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西北师范大学学报（自然科学版） 2024年第5期60卷 10-19页

作者：裴强强赵林毅张博尚东娟赵国靖敦煌研究院甘肃敦煌736200 国家古代壁画保护工程技术研究中心甘肃敦煌736200 古代壁画保护国家文物局重点科研基地甘肃敦煌736200 甘肃莫高窟文化遗产保护设计咨询有限公司甘肃敦煌736200

糯米浆是我国古代应用最广泛的建筑胶凝材料,可显著提高三合土和灰浆的强度特性、抗渗特性和粘结特性.挖掘糯米浆的科学价值,对于传统技术的科学利用,特别是对古建筑的修复具有十分重要的意义.文中用石油醚对糯米粉进行脱脂,采用双波长... 详细信息

糯米浆是我国古代应用最广泛的建筑胶凝材料,可显著提高三合土和灰浆的强度特性、抗渗特性和粘结特性.挖掘糯米浆的科学价值,对于传统技术的科学利用,特别是对古建筑的修复具有十分重要的意义.文中用石油醚对糯米粉进行脱脂,采用双波长法对糯米粉中的直链淀粉和支链淀粉进行测定,用FT-IR,XRD,TG/DTG和SEM分析了糯米粉脱脂前后的结构和形貌,同时用XRD和SEM分析了冻融循环、Na 2SO 4加入对糯米淀粉结构、晶型和形貌的改变,用Brabender粘度仪研究了不同条件下的糊化特性.结果表明,糯米粉中直链淀粉和支链淀粉的含量分别为9.16%和78.56%,糯米粉和脱脂糯米粉的糊化温度基本相同,但峰值粘度、崩解值和回升值下降.冻融循环不会改变糯米粉中淀粉颗粒的结构和晶型,但峰值粘度、谷值粘度、终值粘度、崩解值和回升值均有降低趋势;加入4%的Na 2SO 4后,会使糊化温度升高,崩解值升高,回升值下降.本研究对糯米粉的科学认知具有重要的意义,期望为针对性地提高糯米浆的胶凝品质提供理论参考.

关键词：糯米粉冻融循环盐作用 Brabender粘度曲线糊化特性

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大食物观视域下全谷物食品消费实现路径研究

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粮油食品科技 2024年第1期32卷 12-20页

作者：陈宽宇赵伊琳张弟王建辉王雅轩翟小童谭斌魏珣北京科技大学生物农业研究院北京100083 国家粮食和物资储备局科学研究院粮油加工研究所北京100037

在大食物观视域下,全谷物食品消费对节粮减损和国民营养健康具有积极意义,是未来食品领域的重要发展方向之一,但当前我国全谷物食品消费量远低于推荐水平。本文分析了北美、欧洲、亚洲和非洲地区的主要国家全谷物食品消费的总量、结构... 详细信息

在大食物观视域下,全谷物食品消费对节粮减损和国民营养健康具有积极意义,是未来食品领域的重要发展方向之一,但当前我国全谷物食品消费量远低于推荐水平。本文分析了北美、欧洲、亚洲和非洲地区的主要国家全谷物食品消费的总量、结构以及政策环境,并从产品、消费者、市场与政策四个维度分析了影响全谷物食品消费的主要因素。综上,应着力培养居民的全谷物消费意识、创新全谷物食品的加工技术,通过政策支持发展营养导向型农业,以此打通全谷物食品消费的实现路径,促进全谷物食品产业发展。

关键词：全谷物消费大食物观影响因素实现路径

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Property changes of anchor grout calcined ginger nuts admixed with fly ash and quartz sand after accelerated ageing tests

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Journal of Central South University 2019年第11期26卷 3114-3125页

作者： ZHANG Jing-ke ZHANG Li-xiang zhao lin-yi LIU Dun GUO Qing-lin PEI Qiang-qiang School of Civil Engineering and Mechanics Lanzhou UniversityLanzhou 730000China Key Laboratory of Mechanics on Disaster and Environment in Western China Ministry of EducationLanzhou 730000China National Research Center for Conservation of Ancient Wall Paintings and Earthen Sites Dunhuang AcademyDunhuang 736200China

Calcined ginger nuts admixed by fly ash and quartz sand (CGN-(F+S)) has been validated to be basically compatible to earthen sites as an anchor grout. Accelerated ageing tests including water stability test, temperature and humidity cycling test, soundness test and alkali resistance test are conducted with the objective to further research the property changes of CGN-(F+S) grout. Density, surface hardness, water penetration capacity, water permeability capacity, soluble salt, scanning electron microscopy (SEM) images and energy dispersive spectrometry (EDS) spectrum of these samples have been tested after accelerated ageing tests. The results show that densities of samples decrease, surface hardness, water penetration capacity and water permeability capacity of samples increase generally. Besides, soluble salt analysis, SEM and EDS results well corroborate the changes. Based on the results it can be concluded that property changes are most serious after temperature and humidity cycling test, followed by water stability, soundness and alkali resistance test in sequence. But in general, CGN-(F+S) still has good durability.

关键词： CGN-(F+S) grout accelerated ageing tests physical property change chemical property change scanning electron microscopy energy dispersive spectrometry

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Broadband absorption performance of 3D-printed polyetheretherketone-based electromagnetic wave-absorbing composites

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Chinese Journal of Aeronautics 2024年第8期37卷 547-558页

作者： lin BAI Nan CHANG Meiying zhao Chi HOU yi CAO Dichen LI School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China Chengdu Aircraft Design and Research Institute Chengdu 610091China Xi’an Key Laboratory of Advanced Structure Design and Application of Aircraft Northwestern Polytechnical UniversityXi’an 710072China State Key Laboratory for Manufacturing System Engineering Xi’an Jiaotong UniversityXi’an 710054China

The rapid development of additive manufacturing technology has offered a new avenue for designing and fabricating high wave-absorbing meta *** this study,the mechanical properties and broadband absorption performance of Poly-Ether-Ether-Ketone(PEEK)–based electromagnetic wave–absorbing composite materials was *** high-performance polymer PEEK was used as the matrix,and the materials with electromagnetic wave loss,such as reduced graphene oxide,Carbonyl Iron(CI),and Flake CI(FCI),were used as *** on the theory of impedance matching,a wave-absorbing structure with a gradual impedance gradient was designed and *** test results showed that at the 2.0–18.0 GHz frequency band,the coverage rate of the effective absorption bandwidth was up to 72.0%,the average optimal reflectivity was–18.09 dB,and the wide-angle absorption range was 0°–30°.The advantages of additive manufacturing technology in designing and fabricating wave-absorbing structures are presented,demonstrating that the technology is an effective method for creating broadband absorbing structures.

关键词： Absorption performance Additive manufacturing Electromagnetic absorption PEEK composite materials Gradual structure Broadband absorption

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Effect of rare earth on primary carbides in H13 die steel and their addition method:a review

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Journal of Iron and Steel Research International 2024年第3期31卷 531-551页

作者： Jing-feng Wang lin-zhu Wang Chao-yi Chen Xiang Wang Fei zhao School of Materials and Metallurgy Guizhou UniversityGuiyang 550025GuizhouChina Zhengzhou Railway Vocational and Technical College Zhengzhou 450000HenanChina Guizhou Provincial University Key Laboratory of High Performance Battery Materials Guizhou UniversityGuiyang 550025GuizhouChina Shougang Guiyang Special Steel Co. Guiyang 550005GuizhouChina

Larger-sized primary carbides lead to stress concentration during the application of H13 hot-work die steel,resulting in microcracks and fatigue *** earth was usually added to modify the carbides and *** existing literature is reviewed on the effect of rare earth on primary carbides in H13 steel.A comprehensive review on the effect of rare earth on the characteristics of primary carbides,i.e.,number,size,morphology,and thermal stability in H13 steel,was *** precipitation mechanism and nucleation of primary carbides with rare earth were *** position and form of rare earth in steel and their effects on alloying elements segregation were *** addition techniques of rare earth in H13 steel were compared,and the prospects for other uncommon rare earth and emerging technology were *** on the current references,it can be known that adding rare earth facilitated refined and dispersed primary *** size of primary carbides would be reduced,and their morphology would be improved because the rare earth inclusions formed in H13 steel can act as nucleation cores forγ-Fe orδ-Fe,refining the dendritic ***,the number of primary carbides at grain boundaries would be significantly ***,rare earth had little impact on thermal *** nucleation of primary carbides tended to be inhibited due to the modification of inclusions by rare earth which were likely to be nucleation cores for primary *** earth had been reported to affect the mechanism and process of primary carbide ***,the addition of rare earth can inhibit the segregation of alloying elements and carbon diffusion by ***,laboratory experiments and theoretical calcu-lations need to be conducted to study the states and evolution of rare earth steels.

关键词： Rare earth H13 die steel Primary carbide Nucleation Dendritic structure

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