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微生物学杂志 2008年第2期28卷 57-60页

作者：方晶李从强柯丽霞赵文科安徽师范大学生命科学学院安徽芜湖241500 河南理工大学资源环境学院河南焦作454000

食用菌多糖具有独特的生理特性和极高的药用价值,已成为当前药物研发的热点。从食用菌多糖的化学结构、提取分离、药用价值和应用等几个方面对其进行了全面的总结和展望。

关键词：食用菌多糖研究

Decision making module based on stochastic magnetic tunnel junctions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 202-209页

作者： Yifan Miao Li zhao Yajun Zhang Zhe Yuan Center for Advanced Quantum Studies and Department of Physics Beijing Normal University Institute for Nanoelectric Devices and Quantum Computing Fudan University Interdisciplinary Center for Theoretical Physics and Information Sciences Fudan University

In biological neural systems, noise is ubiquitous but does not affect the correct decisions made in the complex cognitive ***-making in biological neural system is typically achieved by accumulating input information over a period of *** by recent developments in neurosciences, we design a decision-making module based on spintronic devices, utilizing superparamagnetic tunnel junctions as artificial neurons. The feasibility of this decision-making module is verified through circuit simulations. Taking a multi-layer perceptron as an example, the module significantly improves the accuracy of the perceptron in the handwritten digit recognition task. Furthermore, the spintronic decision-making module offers advantages over the conventional pooling methods, such as adaptive decision time, high performance and the absence of analog-to-digital conversion. The decision-making module is flexible to be integrated into artificial neural networks and provides a general yet effective solution to enhance performance against device noise.

关键词： neuromorphic computing spintronics magnetic tunnel junction neural networks

A versatile synthetic strategy towards rare earth based metal-organic frameworks

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Science China Chemistry 2025年

作者： Quan Shi Yun-Hao Xu Ming-Hui Chen Peng zhao wen-Bo Deng Ji Xiong Kai Guo Ya-Qing Feng Bao Zhang School of Chemical Engineering and Technology Tianjin University Tianjin Collaborative Innovation Center of Chemical Science and Engineering Guangdong Laboratory Chemistry & Fine Chemical Industry Jieyang Center

Rare earth metal-organic frameworks (RE-MOFs) have drawn wide attention owing to diverse network structures and various application ***,due to the unpredictable formation of the nodes,it is still challenging to design novel RE-MOFs.A novel versatile strategy was developed employing a RE-acetate complex (RE2(CH3COO)6·4H2O) as a precursor to construct RE-MOFs.2D RE-MOFs (RE-DBP) and 3D RE-MOFs (RE-TCPP) could be obtained by using dicarboxylic porphyrin ligands H2DBP and tetracarboxylic porphyrin ligands H2TCPP,*** RE-MOFs were further synthesized to verify the universality of the *** crystalline RE-MOFs could also be prepared at room temperature via the developed strategy,which could significantly promote large-scale preparation and practical application of *** proof of the concept,the performance of porphyrin-based RE-MOFs was investigated in the photocatalytic cycloaddition of CO2with *** the RE-DBP(Co) MOFs,Tb-DBP(Co) exhibited the best photocatalytic performance,which was also greater than that of the corresponding 3D MOF Tb-TCPP(Co) due to the optimal 2D structure and thus the accelerated photogenerated charge separation and transfer *** work not only provides a novel versatile strategy to design and develop RE-MOFs,but also proposes a promising approach for the potential bulk production of RE-MOFs at room temperature.

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Gradient maturation experiment on hairs implies taphonomic changes in fossil hairs

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Science China Earth Sciences 2025年第1期68卷 62-73页

作者： Xin LI Yibo ZHOU Tao zhao Xingjian HE Yanhong PAN State key Laboratory for Mineral Deposits Research Center for Critical Earth Material Cycling Centre for Research and Education on Biological Evolution and Environment and Frontiers Science School of Earth Sciences and Engineering Nanjing University Institute of Palaeontology Yunnan Key Laboratory of Earth System Science Yunnan Key Laboratory for PalaeobiologyYunnan University

Mammalian hair, as a key feature related to endothermy, physical protection, and camouflage, has a long geohistorical record that dates back even to the Mesozoic. However, the limited information on the taphonomy of hair hinders the understanding of its evolutionary significance in deep time. To address this, we conducted taphonomic experiments to simulate the transformation process of black hair. The changes in the morphological structure, microscopic characteristics, and chemical composition of hair during the simulated fossilization process were documented by scanning electron microscopy, Fourier transform infrared(FTIR) spectroscopy, and Raman spectroscopy. Our results revealed that damage to the morphology of hair began at a mild temperature(150–175°C), and hair transformed into a fluid-like mass at a relatively high temperature(200°C). In addition, the morphological structure of melanosomes had relatively greater preservation potential than keratins did, and the microscopic features of melanosomes were persistently stable. The Raman and FTIR spectra indicated that the characteristic melanin and keratin peaks changed as the temperature increased. Although the chemical signals were not lost completely, the variations in the characteristic amide bands in the FTIR spectra indicate that the keratins severely degraded at high temperatures(>200°C), whereas the characteristic melanin bands in the Raman spectra suggested that melanin signals were still recognizable, even at high temperatures(>200°C). These results were confirmed by principal component analysis(PCA) and principal component analysis linear discriminant analysis(PCA–LDA). In addition, the Raman signals of all the samples in the simulated experiments were distinguished from the signals of common geological carbonaceous materials(humic acid), which suggested that Raman spectroscopy can be used to detect melanin in fossils.

关键词： Mammalian hair Melanin keratin Fossilization Experimental taphonomy

BOF-BCC流程生产高品质汽车齿轮钢实践

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钢铁 2009年第6期44卷 38-42页

作者：赵克文陈天明杨素波王新华李宏曾建华北京科技大学冶金与生态工程学院北京100083 攀枝花钢铁集团公司四川攀枝花617067

结合攀钢转炉-LF-RH-大方坯连铸工艺装备条件,针对高品质汽车用齿轮钢的质量要求,重点开展了精炼渣开发、钢包渣组成控制、脱氧工艺、钙处理及成分精度控制等相关技术研究。试验结果表明:采用该工艺可生产w(T[O])≤10×10-6,夹杂物种类... 详细信息

结合攀钢转炉-LF-RH-大方坯连铸工艺装备条件,针对高品质汽车用齿轮钢的质量要求,重点开展了精炼渣开发、钢包渣组成控制、脱氧工艺、钙处理及成分精度控制等相关技术研究。试验结果表明:采用该工艺可生产w(T[O])≤10×10-6,夹杂物种类、形态和尺寸得到有效控制的高品质汽车用齿轮钢。

关键词： 20CrMoH 转炉精炼大方坯连铸 T[O] 夹杂物

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减少冷轧IF钢表面条痕缺陷的生产实践

钢铁 2010年第9期45卷 44-47页

作者：曾建华吴国荣陈永杨素波杨金成赵克文攀枝花钢铁研究院材料所四川攀枝花617000 攀钢钢钒公司技术质量部四川攀枝花617063 攀钢(集团)公司科技部四川攀枝花617067

针对攀钢IF钢冷轧板出现的条痕缺陷,在对冷轧板、热轧板及铸坯取样分析的基础上,得出铸坯皮下微裂纹、浇铸过程保护渣卷渣以及铸坯中的夹杂物是IF钢冷轧板条痕缺陷产生的主要原因。通过采取降低钢包顶渣氧化性、控制渣中w(CaO)/w(Al2O3... 详细信息

针对攀钢IF钢冷轧板出现的条痕缺陷,在对冷轧板、热轧板及铸坯取样分析的基础上,得出铸坯皮下微裂纹、浇铸过程保护渣卷渣以及铸坯中的夹杂物是IF钢冷轧板条痕缺陷产生的主要原因。通过采取降低钢包顶渣氧化性、控制渣中w(CaO)/w(Al2O3)比值,延长RH脱氧合金化后的循环时间、控制铸机拉速及提高保护渣黏度等技术措施后,冷轧板的条痕缺陷得到了有效控制,因条痕缺陷引起的降级改判率由10.97%降至1.00%以下。

关键词： IF钢条痕缺陷连铸保护渣精炼工艺

Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis

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Science China Life Sciences 2025年第1期68卷 103-115页

作者： Xizi Luo Nan Zhang Yuntao Liu Beibei Du Xuan Wang Tianxu zhao Bingqiang Liu Shishun zhao Jiazhang Qiu Guoqing Wang State key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Basic MedicineJilin University State key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Veterinary MedicineJilin University College of Mathematics Jilin University Bioinformatic Lab School of MathematicsShandong University Department of Cardiology China-Japan Union HospitalJilin University

The coronavirus disease 2019（COVID-19） outbreak caused by the severe acute respiratory syndrome coronavirus-2（SARS-CoV-2） developed into a global health emergency. Systemic microthrombus caused by SARS-CoV-2 infection is a common complication in patients with COVID-19. Cardiac microthrombosis as a complication of SARS-CoV-2 infection is the primary cause of cardiac injury and death in patietns with severe COVID-19. In this study, we performed single-cell sequencing analysis of the right ventricular free wall tissue from healthy donors,patients who died during the hypercoagulable period of characteristic coagulation abnormality（CAC）, and patients who died during the fibrinolytic period of CAC. We collected 61,187 cells enriched in 24 immune cell subsets and 13 cardiac-resident cell subsets. We found that in the course of SARS-CoV-2 infected heart microthrombus, MYO1EhighRASGEF1Bhighmonocyte-derived macrophages promoted hyperactivation of the immune system and initiated the extrinsic coagulation pathway by activating chemokines CCL3, CCL5. This series of events is the main cause of cardiac microthrombi following SARS-CoV-2 infection. In a SARS-CoV-2 infected heart microthrombus, excessive immune activation is accompanied by an increase in cellular iron content, which in turn promotes oxidative stress and intensifies intercellular competition. This induces cells to alter their metabolic environment, resulting in increased sugar uptake via the glycosaminoglycan synthesis pathway. In addition, high levels of reactive oxygen species generated by elevated iron levels promote increased endogenous malondialdehyde synthesis in a subpopulation of cardiac endothelial cells. This exacerbates endothelial cell dysfunction and exacerbates the coagulopathy process.

关键词： SARS-CoV-2 cardiac microthrombosis immune hyperactivation cell competition

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基于近红外光谱技术的烟丝掺配均匀度测定

食品与机械 2020年第11期36卷 183-188页

作者：赵科文陈实蒋浩李龙军罗泽松尹中尉张兴麟刘静贵州中烟工业有限责任公司毕节卷烟厂贵州毕节551700 云南同创检测技术股份有限公司云南昆明650106

根据标准选取糖碱比与钾的乘积作为掺配均匀性评价标志指标,以500个烟丝、500个梗丝、250个再造烟叶丝和30个生产线配方烟丝样品为研究对象,通过采集样品的近红外光谱信息和测定标志指标,利用模式识别和校正模型的建立,系统构建烟丝、... 详细信息

根据标准选取糖碱比与钾的乘积作为掺配均匀性评价标志指标,以500个烟丝、500个梗丝、250个再造烟叶丝和30个生产线配方烟丝样品为研究对象,通过采集样品的近红外光谱信息和测定标志指标,利用模式识别和校正模型的建立,系统构建烟丝、梗丝和再造烟丝掺配均匀性评价方法。结果表明:①PLS-DA模式识别分析4种烟丝样品的近红外光谱整体信息存在较大差异性;②烟丝、梗丝和再造烟叶丝掺配均匀性指标的均值分别为20.64%,273.81%,30.40%,梗丝样品掺配均匀性指标值和波动范围均大于烟丝和再造烟丝样品;③掺配均匀性指标值以50为分类阈值时,3种烟丝样品近红外光谱的PCA-MD呈明显的分类现象,并以50为分类阈值建立了3种烟丝的分段校正模型;④将未参与建模的4种烟丝和配方烟丝样品通过PCA-MD模式识别,判定适宜的分段模型验证后,利用分段模型预测其标志指标,含量与实际测定结果无显著性差异。该研究建立了烟丝掺配均匀性的快速评价方法,分析结果稳定性和准确性均较好。

关键词：掺配均匀性近红外烟丝梗丝再造烟叶丝校正模型判别模型

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基于新型粒子群优化粒子滤波的故障诊断方法

计算机应用 2012年第2期32卷 432-435,439页

作者：陈志敏薄煜明吴盘龙田梦楚黎绍鑫赵文科南京理工大学自动化学院南京210094

针对基于粒子群优化算法的粒子滤波(PSO-PF)算法精度不高,容易陷入局部最优,难以满足电厂温控系统故障诊断的需求,提出一种适用于故障诊断的新型粒子群优化粒子滤波(NPSO-PF)算法。该算法引入社会个体对群体的认知规律优化了粒子更新的... 详细信息

针对基于粒子群优化算法的粒子滤波(PSO-PF)算法精度不高,容易陷入局部最优,难以满足电厂温控系统故障诊断的需求,提出一种适用于故障诊断的新型粒子群优化粒子滤波(NPSO-PF)算法。该算法引入社会个体对群体的认知规律优化了粒子更新的方式,并且完善了粒子速度的更新策略,对优势速度赋有较小概率的变异,提高了粒子的寻优能力,同时随机初始化劣势速度,保证了样本的多样性。实验结果表明,与PSO-PF相比,NPSO-PF提高了故障检测的精度和鲁棒性,可以有效地应用于温控系统故障的诊断。

关键词：粒子群优化粒子滤波温控系统变异故障诊断

《中华内分泌代谢杂志》2003至2005年载文、引文及著者的统计分析

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中华内分泌代谢杂志 2007年第4期23卷 379-382页

作者：滕洪松周晓彬张超英赵文科鲁晓晴青岛大学医学院图书馆 266021 青岛大学医学院预防医学教研室 266021 青岛大学医学院医学研究生教育管理办公室 266021

用文献计量学的方法对2003至2005年《中华内分泌代谢杂志》的载文、引文和著者的情况进行统计分析,3年载文640篇,期均载文量37篇,篇密度为0.37,平均发表时滞14.0个月,基金项目论文占38.0%;著者来自32个省、自治区及直辖市,合著率94.2%,... 详细信息

用文献计量学的方法对2003至2005年《中华内分泌代谢杂志》的载文、引文和著者的情况进行统计分析,3年载文640篇,期均载文量37篇,篇密度为0.37,平均发表时滞14.0个月,基金项目论文占38.0%;著者来自32个省、自治区及直辖市,合著率94.2%,合作度5.26;95.6%的论文有引文,96.8%的引文来自期刊,普莱斯指数为57.3%。《中华内分泌代谢杂志》是一个高质量的学术期刊,具有广泛的社会影响力,积极推动着我国内分泌代谢专业的发展和建设。

关键词：文献计量中华内分泌代谢杂志载文分析引文分析著者分析