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Sleep disturbances and psychomotor retardation in the prediction of cognitive impairments in patients with major depressive disorder

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World Journal of Psychiatry 2024年第10期14卷 1474-1483页

作者： Mi Wang Wen-Tao Chen Hao-Ting Wang Bang-Shan Liu Yu-Meng Ju qiang-Li Dong Xiao-Wen Lu Jin-Rong Sun Liang Zhang Hua Guo fu-Tao zhao Wei-Hui Li Li Zhang Ze-Xuan Li Mei Liao Yan Zhang Jin Liu Ling-Jiang Li Department of Mental Health Center Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina National Clinical Research Center of Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina Department of Psychiatry National Clinical Research Center for Mental DisordersThe Second Xiangya Hospital of Central South UniversityChangsha 410011Hunan ProvinceChina Department of Psychiatry Zhumadian Psychiatric HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Symptoms of depression and comorbid anxiety are known risk factors for cognitive impairment in major depressive disorder(MDD).Understanding their relationships is crucial for developing targeted interventions to mitigate cognitive impairments in MDD *** expect that the severity of sleep disturbances and other depressive symptoms will be positively correlated with the degree of cognitive *** also hypothesize that anxiety symptoms,especially psychic anxiety,is a key factor in predicting cognitive performance in MDD patients and may indirectly contribute to cognitive impairment by affecting sleep disturbances and other potential *** To determine which dimension of the depressive and anxiety symptoms predicts cognitive impairment during a depressive *** A comprehensive neurocognitive test battery assessed executive function,attention,processing speed,and memory in 162 medication-free MDD patients and 142 matched healthy *** 24-item Hamilton Depression Rating Scale was used to assess depressive symptoms,and the 14-item Hamilton Anxiety Scale was used to assess anxiety *** regression analyses and mediation analyses were conducted to evaluate the impact of depressive and anxiety symptoms,as well as their interactions,on cognitive *** Among the depressive symptoms,sleep disturbances were associated with poorer executive function(P=0.004),lower processing speed(P=0.047),and memory impairments(Pfunction[β=-0.013,BC CI(-0.027,-0.001)]and memory[β=-0.149,BC CI(-0.237,-0.063)],while PR mediated its ef

关键词： Major depressive disorder Cognitive impairment Depressive symptoms Anxiety symptoms Sleep disturbance Psychomotor retardation

The geochemical evidences of sulphur oil sources in the BZ35/36 structures of the Huanghekou Sag, Bohai Bay Basin, China

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Petroleum Research 2019年第2期4卷 164-172页

作者： qiang fu Binbin Liu Chengmin Niu Shijie zhao State Key Laboratory of Marine Geology School of Marine and Earth ScienceTongji UniversityShanghai200092China Tianjin Branch of Exploration and Development Research Institute CNOOC(China)co.LTDTianjin300452China

Crude oils in the BZ35/BZ36 fields found within the Paleogene Dongying and Shahejie formations in the Huanghekou Sag of the Bohai Bay Basin,China have generally high density,viscosity,and sulfur *** physical properties and geochemical features have obvious differences when compared with crude oils from other structures within the Huanghekou *** comparison and analysis of biomarkers(e.g.,pristine/phytane,gammacerane,C24Te/C26TT,C2920S/(20Sþ20R),C29bb/(bbþaa),etc.)show that sour crude oil from the BZ35/BZ36 fields is similar to the sour oil in the Miaoxi Sag adjacent to the eastern of Huanghekou ***,low maturity oils in the Miaoxi Sag have likely migrated southwest,while the sweet,higher maturity oils in the Huanghekou Sag have migrated *** oils generated from these two sags have focused in the BZ35/BZ36 *** source rock of the sour crude oil was most likely formed in a dry climate and strong reducing saline lake.

关键词： Bohai Bay Basin Huanghekou sag Sour crude oil Biomarker Hydrocarbon charging

Chirality Transfer in Supramolecular Co-assembled Fibrous Material Enabling the Visual Recognition of Sucrose

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Advanced Fiber Materials 2020年第4期2卷 204-211页

作者： Nabila Mehwish Xiaoqiu Dou Changli zhao Chuanliang Feng qiang fu State Key Lab of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiaotong UniversityDongchuan Rd 800Shanghai 200240China State Key Laboratory of Polymer Materials Engineering College of Polymer Science and EngineeringSichuan UniversityChengdu 610065China

Molecular recognition of simple sugars is crucial due to their essential roles in most living ***,it remains extremely challenging to achieve a visual recognition of simple sugars like sucrose in water media under physiological *** this article,the visual recognition of sucrose is accomplished by a chiral supramolecular hydrogel formation through the co-assembly of a two-component fibrous solution(l-phenylalanine based gelator co-diaminopyridine,LDAP)and sucrose.H-bonding between the amino group of LDAP and the hydroxyl group of sucrose facilitates the gelation by loading sucrose into the LDAP *** formed hydrogel showed an amplified inversion of circular dichroism(CD)signals as compared to the corresponding LDAP *** addition,the effective chirality transfer was accompanied by a bathochromic shift in UV-Vis and FL spectra of the *** a simple and straightforward chiral co-assembled strategy to visually recognize sucrose will have the potential use of smart gelators in saccharides separation and proteomics to be further applied in medical diagnostics and cell imaging.

关键词： Supramolecular hydrogels Chirality inversion Molecular recognition Sugars Sucrose Glucose

A Modeling Study of Effective Radiative Forcing and Climate Response Due to Tropospheric Ozone

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Advances in Atmospheric Sciences 2016年第7期33卷 819-828页

作者： Bing XIE Hua ZHANG Zhili WANG Shuyun zhao qiang fu Key Laboratory for Semi-Arid Climate Change of the Ministry of Education College of Atmosphere ScienceLanzhou UniversityLanzhou 730000 Laboratory for Climate Studies of China Meteorological Administration National Climate CenterChina Meteorological AdministrationBeijing 100081 Chinese Academy of Meteorological Sciences Beijing 100081 Department of Atmospheric Sciences University of WashingtonSeattle98195USA

This study simulates the effective radiative forcing （ERF） of tropospheric ozone from 1850 to 2013 and its effects on global climate using an aerosol-climate coupled model, BCC_AGCM2.0. I_CUACE/Aero, in combination with OMI （Ozone Monitoring Instrument） satellite ozone data. According to the OMI observations, the global annual mean tropospheric col- umn ozone （TCO） was 33.9 DU in 2013, and the largest TCO was distributed in the belts between 30°N and 45°N and at approximately 30°S; the annual mean TCO was higher in the Northern Hemisphere than that in the Southern Hemisphere; and in boreal summer and autumn, the global mean TCO was higher than in winter and spring. The simulated ERF due to the change in tropospheric ozone concentration from 1850 to 2013 was 0.46 W m-2, thereby causing an increase in the global annual mean surface temperature by 0.36°C, and precipitation by 0.02 mm d-1 （the increase of surface temperature had a significance level above 95%）. The surface temperature was increased more obviously over the high latitudes in both hemispheres, with the maximum exceeding 1.4°C in Siberia. There were opposite changes in precipitation near the equator, with an increase of 0.5 mm d- 1 near the Hawaiian Islands and a decrease of about -0.6 mm d- 1 near the middle of the Indian Ocean.

关键词： tropospheric ozone effective radiative forcing climate effect BCC_AGCM2.0. I_CUACE/Aero

陇中黄土丘陵沟壑区果树经济林枯落物持水特性分析与探讨——以葫芦河流域果树经济林地为例

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中国水土保持 2024年第4期 57-60页

作者：赵强王辅张鹤沙小燕何倩韩芬平凉市水土保持科学研究所甘肃平凉744000

为分析陇中黄土丘陵沟壑区葫芦河流域果树经济林(苹果)地、山杏水保林地和自然裸地的枯落物持水过程及其特性,通过室内浸水试验,分别对不同地类枯落物蓄积量、持水量、持水率、吸水速率和拦蓄量等水文特性指标进行了对比分析,结果表明:... 详细信息

为分析陇中黄土丘陵沟壑区葫芦河流域果树经济林(苹果)地、山杏水保林地和自然裸地的枯落物持水过程及其特性,通过室内浸水试验,分别对不同地类枯落物蓄积量、持水量、持水率、吸水速率和拦蓄量等水文特性指标进行了对比分析,结果表明:3种地类枯落物蓄积量在2.80~4.23 t/hm^(2)之间,最大持水量在6.27~14.46 t/hm^(2)之间,有效拦蓄量在5.05~11.55 t/hm^(2)之间,均表现为果树经济林(苹果)地>山杏水保林地>自然裸地;枯落物的吸水速率与时间之间呈显著的负相关幂函数关系,吸水速率在0~2 h内急剧下降,4 h后趋于平缓,24 h后趋近于0。因此,栽植果树经济林不仅具有产业经济价值,而且其枯落物具有与水保林相同或更高的蓄水保土特性,对改善土壤结构、增加土壤有机质、提高土壤肥力、增加土壤墒情具有重要作用。

关键词：果树经济林枯落物持水特性葫芦河流域陇中黄土丘陵沟壑区

Effects of airfoil on aerodynamic performance of flapping wing

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Biomimetic Intelligence & Robotics 2021年第1期1卷 31-35页

作者： Min zhao Yao Zou qiang fu Wei He School of Automation and Electrical Engineering University of Science and Technology BeijingBeijing 100083China Institute of Artificial Intelligence University of Science and Technology BeijingBeijing 100083China

Flapping-wing aircraft(FWA)operates in a flight mode that mimics natural flyers,such as birds,bats and *** large scale bird-inspired flapping wings aircraft,the design of airfoil parameters is crucial to improving the aerodynamic *** order to study the effect of camber on the aerodynamic characteristics,we developed four different airfoils with a chord length of 12 *** cambers of airfoils are respectively 30 mm,25 mm,20 mm and 15 mm.A numerical investigation into the effects of camber on aerodynamic performance is carried out through COMSOL Multiphysics software using Fluid–Structure Interaction(FSI)*** this work,the fluid–structure module employs the Navier–Stokes equations coupled with a solid stress–strain physics module and a moving mesh *** three-dimensional(3D)flapping wing computational models with different cambers are *** results show that certain camber of airfoil can improve the aerodynamic characteristics of flapping wing.

关键词： Aerodynamic performance Airfoil Camber FIS COMSOL

CMS实验中大动量玻色子喷注探针方法的发展及应用

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科学通报 2024年第22期69卷 3208-3221页

作者：高乐耘付大为赵宇哲郭启隆钱思天杨天一邓森李强北京大学核物理与核技术国家重点实验室北京100871

过去10余年来,大动量玻色子喷注的标记方法受到高能物理理论及实验界的极大关注,已经成为高能量物理前沿领域的推动技术和创新亮点.大动量玻色子常常作为共振产生的重粒子的衰变产物,广泛出现于超出标准模型的新粒子和新物理的寻找工作... 详细信息

过去10余年来,大动量玻色子喷注的标记方法受到高能物理理论及实验界的极大关注,已经成为高能量物理前沿领域的推动技术和创新亮点.大动量玻色子常常作为共振产生的重粒子的衰变产物,广泛出现于超出标准模型的新粒子和新物理的寻找工作中.对大动量的规范玻色子(统称为V)和希格斯玻色子(H),CMS实验组成功开发了V→qq和H→bb等过程的标记技术及校准方案,并成功将其应用于多玻色子共振态的寻找等工作中.本文回顾了10余年来CMS实验中大动量玻色子探针方法的发展及应用,其中包括最新提出的新技术和新方法,特别是人工智能时代到来后出现的与深度学习紧密结合的喷注标记技术.

关键词： CMS实验大动量玻色子探针超出标准模型的新物理深度学习

枯草芽孢杆菌复合制剂对蛋鸡生产性能和肠道菌群的影响

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饲料研究 2024年第15期47卷 34-39页

作者：付强郭时金王建军程立坤赵修报姜忠兴付石军山东省滨州畜牧兽医研究院山东滨州256600 山东绿都生物科技有限公司山东滨州256600

试验旨在探究枯草芽孢杆菌复合制剂对蛋鸡生产性能和肠道菌群的影响。选取30只500日龄体重相近的蛋鸡随机分为2组,每组3个重复,每个重复5只蛋鸡。CK组(对照组)饲喂玉米-豆粕基础饲粮,T组在基础饲粮中添加1 g/kg枯草芽孢杆菌复合制剂。... 详细信息

试验旨在探究枯草芽孢杆菌复合制剂对蛋鸡生产性能和肠道菌群的影响。选取30只500日龄体重相近的蛋鸡随机分为2组,每组3个重复,每个重复5只蛋鸡。CK组(对照组)饲喂玉米-豆粕基础饲粮,T组在基础饲粮中添加1 g/kg枯草芽孢杆菌复合制剂。试验期70 d。结果显示,与CK组相比,T组料蛋比显著降低(P<0.05);在门水平,十二指肠厚壁菌门相对丰度极显著增加(P<0.01),回肠放线菌门相对丰度显著增加(P<0.05),盲肠变形菌门相对丰度极显著降低(P<0.01);在属水平,十二指肠乳杆菌属相对丰度极显著增加(P<0.01),棒状杆菌属丰度极显著降低(P<0.01),回肠肠球菌属和卡多维亚氏菌(Aeriscardovia)相对丰度显著或极显著增加(P<0.05或P<0.01),盲肠理研菌科相对丰度显著增加(P<0.05)。β多样性分析显示,十二指肠和回肠菌群结构具有一定的相似性,且与盲肠菌群结构不同。研究表明,添加枯草芽孢杆菌复合制剂可促进乳酸菌、Aeriscardovia生长,优化了肠道菌群结构,提高了饲料利用率。

关键词：枯草芽孢杆菌复合制剂蛋鸡生长性能肠道菌群高通量测序菌群多样性

维普期刊数据库博看期刊

糖尿病肾脏病“风邪伏络”对“微型癥瘕”的继承发展与“从风治瘀”思路

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中华中医药杂志 2024年第3期39卷 1181-1184页

作者：刘轶凡赵进喜傅强刘媛媛肖遥黄为钧山东中医药大学附属医院内分泌科济南250011 北京中医药大学东直门医院肾病内分泌二区北京100700 北京中医药大学第三附属医院肾病科北京100029

糖尿病肾脏病“风邪伏络”学说是在“微型癥瘕”理论的基础上提出的,认为在继承化瘀散结治法防治“微型癥瘕”的同时,应注重祛除“风邪”对疾病发生发展的影响,认识并处理好风邪与瘀血的关系,活用祛风药物。在广义范畴的风药中,不少药... 详细信息

糖尿病肾脏病“风邪伏络”学说是在“微型癥瘕”理论的基础上提出的,认为在继承化瘀散结治法防治“微型癥瘕”的同时,应注重祛除“风邪”对疾病发生发展的影响,认识并处理好风邪与瘀血的关系,活用祛风药物。在广义范畴的风药中,不少药物具备祛风与化瘀的双重功效,对治疗包含糖尿病肾脏病在内的多种瘀血相关病证具有良好疗效。文章将应用风药来治疗瘀血相关病证的思路概括为“从风治瘀”,是对“从风论治”的总结细化,梳理其在糖尿病肾脏病中的具体应用,有助于提高临床疗效,拓宽瘀血相关病证的治疗思路。

关键词：糖尿病肾脏病微型癥瘕风邪伏络从风治瘀风药