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Single Nucleotide Polymorphism (SNP) Analysis of orexin Gene 5' Regulatory Region in Chinese Indigenous Cattle Populations

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Agricultural Sciences in China 2011年第8期10卷 1273-1279页

作者： zhang ai-ling zhang Li zhang Liang-zhi LAN Xian-yong zhang Cun-lei zhang Cun-fang CHEN Hong Shaanxi Key Laboratory of Molecular Biology for Agriculture College of Animal Science and TechnologyNorthwest A＆F UniversityYangling 712100P.R.China Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding College of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642P.R.China Agricultural College Guangdong Ocean UniversityZhanjiang 524000P.R.China College of Life Sciences Xuzhou Normal UniversityXuzhou 221000P.R.China

Orexin is an important neuropeptide that influences livestock＇s appetite and food intake and is closely related with livestock＇s growth and *** variations in the orexin gene 5＇ regulatory region might have an influence on the gene *** on the hypothesis,five overlapped fragments including 1 794 bp of orexin gene 5＇ regulatory region were investigated for single nucleotide polymorphisms （SNPs） by PCR-SSCP and DNA sequencing in three indigenous cattle populations.A total of five SSCP patterns observed revealed ten SNPs in the *** SSCP patterns genotypes （A and B） were exhibited in O-2 fragment and three （A,B and C） were found in O-5 fragment.O-2 contained four SNPs,viz.,-583 TC,-479 CT,-474 AT,and-451 *** another lous O-5,six SNPs were identified （-1 610 CG,-1 585 GA,-1 550 TC,-1 548 AC,-1 438 CT,and-1 431 CA）.Seven SNPs were found in transcription factor binding sites and four out of them existed in the core *** SNPs at-479,-474 and-451 did not change the putative recognition core sequences of their *** the mutation at-583 changed the binding sequence of EVI1 into NFA and created one new binding site for ZFHX *** three populations,the frequencies of A,B and C genotypes of O-2 were 0.2367,0.4842 and 0.2791,*** the A pattern of O-5 was preponderant （0.7549） and the other B pattern was not （0.2451）.But the frequencies of different SSCP variants varied across three cattle populations.B genotype in O-2 had significant associations to body weight （BW） and daily weight gain （DWG） in Nanyang cattle 6-and 12-mon aged and might serve as one potential candidate genetic marker for growth and development.

关键词： orexin gene promoter SNP cattle

p53 and NFκB regulate microRNA-34c expression in porcine ovarian granulosa cells

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Journal of Integrative Agriculture 2016年第8期15卷 1816-1824页

作者： XU Yuan zhang ai-ling XIAO Guang zhang Zhe CHEN Zan-mou zhang Hao LI Jia-qi Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding College of Animal Science South China Agricultural University College of Biological and Food Engineering Guangdong University of Education

supported by the National Natural Science Foundation of China （31201771）;the earmarked fund for the China Agriculture Research System （CARS-36）

关键词： porcine granulosa cells microRNA-34c expression promoter p53 NFkB

MicroRNA-34c regulates porcine granulosa cell function by targeting forkhead box O3a

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Journal of Integrative Agriculture 2017年第9期16卷 2019-2028页

作者： XU Yuan zhang ai-ling zhang Zhe YUAN Xiao-long CHEN Zan-mou zhang Hao LI Jia-qi Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding College of Animal ScienceSouth China Agricultural University College of Biological and Food Engineering Guangdong University of Education

Granulosa cells（GCs） are somatic cells of ovary, the behaviors of GCs are important for ovarian function. MicroRNAs（miRNAs） are a class of endogenous 18–24 nucleotide（nt） non-coding RNAs, some of which have been shown to be important regulators of GCs function. miR-34c involved in the regulation of various biological processes and was identified to be a pro-apoptotic and anti-proliferative factor in many cell types. However, the roles of miR-34c in GCs function remain unknown. In this study, we used Annexin V-FITC and Ed U assays to demonstrate that miR-34c exerted pro-apoptotic and anti-proliferative effects in porcine GCs. Dual-luciferase reporter assays, quantitative real-time PCR（q RT-PCR） and Western blotting identified Forkhead box O3a（Fox O3a） as a direct target gene of miR-34c. The overexpression of FoxO3a rescued the phenotypic change caused by miR-34c in porcine GCs. In conclusion, miR-34c regulate the function of porcine GCs by targeting FoxO3a.

关键词： porcine microRNA-34c FoxO3a granulosa cell function

Fabrication and characterization of annealed proton exchanged long period waveguide grating in x-cut LiNbO3

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Optoelectronics Letters 2019年第4期15卷 260-263页

作者： zhang ai-ling GENG Bo HAO Li-yue LI Dan Tianjin Key Laboratory of Film Electronic and Communication Devices Engineering Research Center of Ministry of Education for Optoelectronic Devices and Communication Technology School of Electrical and Electronic EngineeringTianjin University of Technology

In this paper, a long-period waveguide grating was fabricated in x-cut lithium niobate substrate by patterned annealed proton exchange waveguide fabrication process. The waveguide mode characteristic was evaluated using a charge-coupled device(CCD) camera. It shows that the waveguide is single mode transmission at a wavelength of1 550 nm. The transmission spectra of the long period waveguide gratings were measured by optical spectrum analyzer(OSA) and show an extinction ratio of ~17 dB and a 3 dB bandwidth of ~10 nm at the resonant wavelength. The resonant wavelength moves toward to the long wavelength direction as the waveguide width-difference increases in the same period, and also shifts toward to the long wavelength direction with the increase of the period in the case of the same waveguide width-difference. The method of fabricating a long period waveguide grating based on a patterned annealed proton exchange technique simplifies the fabrication process, and at the same time, reduces the fabrication cost.

关键词： optical spectrum analyzer(OSA) charge-coupled device(CCD) x-cut LiNbO3

Optical arbitrary waveform generation based on an array of tunable apodized waveguide Bragg gratings

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Optoelectronics Letters 2020年第3期16卷 195-199页

作者： zhang ai-ling CHENG Qi-hang SONG Hong-yun PAN Hong-gang Tianjin Key Laboratory of Film Electronic and Communication Devices Engineering Research Center of Ministry of Education for Optoelectronic Devices and Communication TechnologySchool of Electrical and Electronic EngineeringTianjin University of TechnologyTianjin 300384China

A structure of optical arbitrary waveform generation(OAWG)based on an array of tunable apodized waveguide Bragg gratings(WBGs)is *** WBGs array on lithium niobate(LN)consists of several apodized gratings,waveguides and electrodes deposited on both sides of gratings and *** properties of OAWG are analyzed using transfer matrix *** to the electro-optic effect of LN,the amplitude and phase of incident light source are controlled via adjusting the voltages on ***,the optical pulses with different waveforms are obtained and the amplitude is linearly *** addition,voltages compensating amplitude and phase distortion are demonstrated.

关键词： waveguide tunable waveform

同步发电机突然从电网切除后端电压分析及参数求取

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中国电机工程学报 2000年第12期20卷 28-32,37页

作者：张爱玲太原理工大学电力学院山西省太原市030024

采用运算微积方法分析了同步发电机突然从电网切除后端电压的变化规律 ,以及如何利用这一瞬变过程求取同步发电机的参数。通过在 1台小型同步发电机上的试验表明 ,参数计算的重复性较好 ,模拟计算结果和试验结果接近。

关键词：同步发电机电网端电压参数辨识

Humidity and temperature sensor based on GOQDs-PVA coated tapered no-core fiber combined with FBG

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Optoelectronics Letters 2020年第6期16卷 428-432页

作者： CHENG Qi-hang zhang ai-ling PAN Hong-gang LI Wen SUN Ce Tianjin Key Laboratory of Film Electronic and Communication Devices Engineering Research Center of Communication Devices and TechnologyMinistry of EducationSchool of Electrical and Electronic EngineeringTianjin University of TechnologyTianjin 300384China

A simple structure optical fiber sensor for relative humidity(RH) and temperature measurement is proposed and verified in this paper, which is based on graphene oxide quantum dots and polyvinyl alcohol(GOQDs-PVA) composite coated tapered no-core fiber(NCF) combined with a fiber Bragg grating(FBG). FBG is insensitive to humidity and sensitive to temperature, which is used to compensate temperature of the sensor. Experimental results show this sensor has humidity sensitivity of 143.27 pm/%RH ranging from 30%RH to 80%RH and the temperature sensitivity of 9.21 pm/℃. The proposed sensor has advantages of simple structure, good repeatability, and good stability, which is expected to be used in both RH and temperature measurement in biological and chemical fields.

关键词： NCF red Humidity and temperature sensor based on GOQDs-PVA coated tapered no-core fiber combined with FBG PVA

溪洛渡送电广东同塔双回直流输电工程控制保护策略研究

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电力系统保护与控制 2011年第9期39卷 72-76页

作者：张爱玲许继电气股份有限公司河南许昌461000

溪洛渡右岸送电广东直流输电工程采用同塔双回输电方式,双回±500kV直流系统在整流站和逆变站共用交流场和接地极系统。针对溪右直流输电工程的特点,在PSCAD/EMTDC仿真平台上利用自定义功能块搭建了双回直流系统较完善的控制保护仿真模... 详细信息

溪洛渡右岸送电广东直流输电工程采用同塔双回输电方式,双回±500kV直流系统在整流站和逆变站共用交流场和接地极系统。针对溪右直流输电工程的特点,在PSCAD/EMTDC仿真平台上利用自定义功能块搭建了双回直流系统较完善的控制保护仿真模型,对双回直流系统的极控制策略、同步协调控制策略、无功功率控制策略及直流线路保护策略进行了比较深入的研究。所提出的控制保护策略可对双回直流系统进行有效的运行控制和保护,研究成果对实际工程的实施具有重要意义。

关键词：同塔双回高压直流输电控制保护仿真模型 PSCAD/EMTDC 策略

基于转矩预测控制的无刷双馈电机直接转矩控制系统

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电机与控制学报 2007年第4期11卷 326-330页

作者：张爱玲张洋太原理工大学电气与动力工程学院山西太原030024

在研究无刷双馈电机直接转矩控制调速系统的基础上,针对无刷双馈电机直接转矩控制转矩脉动大的问题,提出了适用于该种电机的转矩预测法。仿真结果表明,该方法能有效地减小转矩脉动、改善定子电流波形,具有良好的动、静态性能。

关键词：无刷双馈电机直接转矩控制转矩预测