检索结果-南通市图书馆

Comparison of visual performance between conventional LASIK and wavefront-guided LASIK with iris-registration

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2008年第2期121卷 137-142页

作者： zhang Jing ZHOU yue-hua WANG Ning-li LI Rui Ophthalmic Center Beijing Tongren Hospital Capital MedicalUniversity Beijing 100730 China

Background Laser in situ keratomileusis （LASIK） has become an efficient and commonly performed procedure to reduce refractive errors. In order to further increase the postoperative visual quality, the wavefront-guided refractive surgery has been a research hotspot in customized surgery. This study was conducted to compare the visual acuity, higher-order aberration, and contrast sensitivity of wavefront-guided LASIK with iris-registration and conventional LASIK. Methods Two hundred and eleven myopic eyes of 109 patients were enrolled in this prospective study and randomly divided into two groups： the wavefront-guided LASIK （wg LASIK） group （94 eyes） and conventional LASIK group （117 eyes）. A Wavescan Wavefront aberrometer was used to analyze Zernike coefficients and the root-mean-square （RMS） of higher order aberrations with 6.0 mm pupil size, and Optec 6500 visual function instrument was used to measure contrast sensitivity （CS） under 5 spatial frequencies before and after surgery in both groups.Results The uncorrected visual acuity （UCVA） and the mean spherical equivalent （SE） in wg LASIK group were significantly better than those in conventional LASIK （UCVA, z=2.339, P=0.019; SE, t=2.838, P=0.005） at 3 months after surgery. Moreover, the increase in Z3^-3, Z3^1, Z3^3, Z4^0, Z5^-1, Z5^1 Z5^-5 and Z6^-6 in wg LASIK group was statistically smaller than that in conventional LASIK group （P〈0.05）. In wg LASIK group, eyes with a higher amount of the preoperative RMS of the higher order aberrations （RMSh≥0.30μm） showed a statistically lower increase （13.5%） than those in conventional LASIK group at 3 months after surgery （33.3%）（P=0.004）. And the values of 4th order spherical aberration （4thSA） and the root mean square of 6th order aberration （RMS6） in wg LASIK group were significantly lower than those in conventional group in eyes which had higher preoperative astigmatism （≥1.0D）（4thSA, P=0.03; RMS6, P=0.02）. Wg LASIK group showed better CS values than the correspon

关键词： aberration contrast sensitivity visual performance keratomileusis, laser in situ

Case Report:A case of chylothorax treated curatively with Sapylin, a streptococcus preparation

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2007年第12期8卷 885-887页

作者： XU Zhi-hao WANG Chun-fu zhang yue-qin SHEN hua-hao XU Feng Department of Respiratory Diseases the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

Chylothorax is an uncommon disease where fatty fluid accumulates within the chest cavity. Conservative manage- ment, including repeated thoracentesis or pleurodesis, seems to be suitable to most cases. Herein, we present a case of efficacious pleurodesis by intrapleural injection of Sapylin, a streptococcus preparation, for the treatment of chylothorax. A 52-year-old non-smoking female farmer was diagnosed as idiopathic chylothorax after we ruled out possible causes including chest trauma, lymphoma, lung cancer, filariasis, tuberculosis, and etc. Two-time intra-thoracic injection of 3 Klinische Einheit (KE) Sapylin achieved rapid and effective control of chylothorax with no severe side effects. Sapylin may facilitate pleurodesis by producing a strong inflammatory response.

关键词： Chylothorax Sapylin Streptococcus preparation

在线全文

学校读者我要写书评

暂无评论

关注抗癫痫药物的标签外用药

中华儿科杂志 2011年第8期49卷 564-566页

作者：张月华北京大学第一医院儿科 100034

抗癫痫药物（antiepileptic drugs，AEDs）是一批由国家食品与药品监督管理局（SFDA）批准的控制癫痫发作的药物。临床使用的AEDs包括传统的AEDs和80年代以后上市的多种新型AEDs。

关键词：抗癫痫药物食品与药品监督管理局外用药标签 AEDs drugs 癫痫发作临床使用

同方期刊数据库

Drug-eluting stents improve clinical outcomes in Chinese diabetic patients with de novo coronary artery disease

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2006年第18期119卷 1576-1579页

作者： zhang Qi FANG yue-hua zhang Rui-yan HU Jian YANG Zhen-kun NI Jun zhang Jian-sheng SHEN Wei-feng Department of Cardiology Shanghai Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai 200025 China

Diabetes mellitus （DM） has been regarded as an equivalent risk factor as coronary artery disease and is present in nearly 25% of patients who receive percutaneous coronary intervention （PCI）. DM is shown as an adverse predictor for major adverse cardiac events （MACE） after PCI in bare metal stent （BMS） era. Recently, clinical trials have demonstrated the favorable tendency of using drug-eluting stents （DES） in treating diabetic patients with coronary artery disease. This study compared the clinical outcomes between the diabetic patients receiving DES with those receiving BMS in China.

关键词： coronary disease diabetes mellitus drug-eluting stent outcome assessment

Analysis of SSR Fingerprints in Introduced Silkworm Germplasm Resources

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2007年第5期6卷 620-627页

作者： HOU Cheng-xiang LI Mu-wang zhang yue-hua QIAN He-ying SUN Ping-jiang XU An-ying MIAO Xue-xia GUO Qiu-hong XIANG Hui huaNG Yong-ping Sericultural Research Institute Chinese Academy of Agricultural Sciences Zhenjiang 212018 P.R.China Institute of Plant Physiology and Ecology Shanghai Institute for Biological Sciences Chinese Academy of Sciences Shanghai 200032 P.R. China

Thirty-five SSR markers were used to construct 96 silkworm races fingerprint. All the SSR markers were polymorphic and unambiguously separated silkworm strains from each other. A total of 467 alleles were detected with a mean value of 13.34 alleles/locus （range 3-28）. The mean polymorphism index content （PIC） was 0.71 （range 0.299-0.919）. UPGMA cluster analysis of Nei＇s genetic distance grouped silkworm strains on the basis of their origin. The results indicated that SSR markers are efficient tools for fingerprinting cultivars and conducting genetic diversity studies in the silkworm.

关键词： silkworm (Bombyx mori L.) germplasm SSR marker fingerprint

Clinical and laboratory survey of 65 Chinese patients with Leigh syndrome

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2006年第5期119卷 373-377页

作者： YANG Yan-ling SUN Fang zhang Yao QIAN Ning YUAN Yun WANG Zhao-xia QI Yu XIAO Jiang-xi WANG Xiao-ying QI Zhao-yue zhang yue-hua JIANG Yu-wu BAO Xin-hua QIN Jiong WU Xi-ru Department of Pediatrics Peking University First Hospital Beijing 100034 China Department of Neurology Peking University First Hospital Beijing 100034 China Central Lab Peking University First Hospital Beijing 100034 China Department of Medical Radiology Peking University First Hospital Beijing 100034 China

Background Leigh syndrome is an inherited neurodegenerative disease that emerges in infancy and childhood and presents with a clinically heterogeneous variety of neuromuscular and non-neuromuscular disorders. It can result from the inheritance of mutations in either nuclear or mitochondrial DNA. In the current study, we performed a retrospective study in 65 patients in order to investigate the clinical and genetic characteristics of Leigh syndrome in Chinese patients. Methods Sixty-five unrelated cases （35 men and 30 women） who were hospitalized in the past 12 years were reviewed. Diagnosis was based on both the clinical presentation and the characteristic neuropathologic findings of bilateral symmetric necrotizing lesions in the basal ganglia and brain stem as detected using cranial computed tomography （CT） scan or magnetic resonance imaging （MRI）. The differential diagnosis of organic acidurias and fatty acid IS-oxidation defects were performed. Specific point mutations and deletions in mitochondrial DNA （T8993G, T8993C, T9176C, A8344G, A3243G） were screened by PCR-restriction analysis and Southern blot. The SURF1 gene was sequenced. Skeletal muscle biopsies were performed in 17 （26.2%） of the patients. The diagnosis was confirmed by autopsy in 6 （9.2%） patients. Results The patients had various forms of metabolic encephalomyopathy. Filly-nine （90.8%） of the patients had the typical neuroradiological features of Leigh syndrome, including symmetrical necrotizing lesions scattered within the basal ganglia, thalamus and brain stem. Twenty （30.8%） patients were confirmed by genetic, biochemical analysis and autopsy. Specific point mutations in mitochondrial DNA were found in 5 cases （7.7%）. Of these, the A8344G mutation was detected in 2 patients. The T8993G T8993C, and A3243G point mutations were identified in 3 other patients, respectively. SURF1 mutations associated with cytochrome c oxidase deficiency were identified in 8 （12.3%） families by DNA sequencing. A

关键词： Leigh syndrome mitochondrial genes cytochrome c oxidase deficiency SURF1 gene

在线全文

学校读者我要写书评

暂无评论

热敏感相关的癫痫临床和分子遗传学研究

中国实用儿科杂志 2015年第7期30卷 487-491页

作者：张月华北京大学第一医院儿科北京100034

热性惊厥是儿童期最常见的惊厥,但有些遗传相关的癫痫类型也表现为发热容易诱发,即发作具有"热敏感"的特点。热敏感相关的癫痫包括全面性癫痫伴热性惊厥附加症(GEFS+),Dravet综合征(DS)和限于女性的癫痫伴智力低下(EFMR)。文章主要阐述... 详细信息

热性惊厥是儿童期最常见的惊厥,但有些遗传相关的癫痫类型也表现为发热容易诱发,即发作具有"热敏感"的特点。热敏感相关的癫痫包括全面性癫痫伴热性惊厥附加症(GEFS+),Dravet综合征(DS)和限于女性的癫痫伴智力低下(EFMR)。文章主要阐述这3种癫痫类型的临床特点和分子遗传学研究进展。

关键词：热敏感癫痫全面性癫痫伴热性惊厥附加症 Dravet综合征限于女性的癫痫伴智力低下

在线全文

学校读者我要写书评

暂无评论

干式空心电抗器电磁兼容性分析

变压器 2015年第7期52卷 43-45页

作者：张月华北京电力设备总厂有限公司北京102401

对空心电抗器磁场分布情况进行了分析,对金属构架及电气设备在磁场中的温升情况进行了研究,绘制了电抗器的净磁空间,提出了各种特性边界。

关键词：空心电抗器磁场分布温升净磁空

在线全文

学校读者我要写书评

暂无评论

全面性癫伴热性惊厥附加症研究进展

实用儿科临床杂志 2006年第24期21卷 1683-1685页

作者：张月华北京大学第一医院儿科北京100034

全面性癫(癎)伴热性惊厥附加症(generalized epilepsy with febrile sizures plus,GEFS+)为家族性遗传性癫(癎)综合征,由澳大利亚 Sheffer和Berkovic于1997年首先在国际上报道[1].近年来,国际上有关本病的家系报道逐渐增多,其分子遗传... 详细信息

全面性癫(癎)伴热性惊厥附加症(generalized epilepsy with febrile sizures plus,GEFS+)为家族性遗传性癫(癎)综合征,由澳大利亚 Sheffer和Berkovic于1997年首先在国际上报道[1].近年来,国际上有关本病的家系报道逐渐增多,其分子遗传学研究也取得了很大进展,国内也有相关报道[2,3].

关键词：全面性癫痢热性惊厥附加症表型遗传基因