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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 82-92页

作者： Zi-Fa zhang Shu-ming Liu Neurosurgery Department Shanxi Bethune HospitalTaiyuanShanxi Province030022China Shanxi Academy of Medical Sciences TaiyuanShanxi province030022China Emergency Department Taiyuan People’s HospitalTaiyuanShanxi Province030021China

Objective:To explore the regulatory mechanism of NUDT5 in glioblastoma multiforme(GBM).Methods:GEPIA database was used to predict the expressions of NUDT5 and tripartite motif family proteins 47(TRIM47)in GBM ***-qPCR and Western blot analyses were performed to examine NUDT5 expression in GBM ***-229 cell proliferation,migration as well as invasion were estimated by CCK-8,colony formation,wound healing,and Transwell assays following interference with *** assay,L-lactic acid kit,glucose detection kit,and ATP detection kit were applied for the detection of glycolysis-related ***-immunoprecipitation experiment was carried out to verify the relationship between NUDT5 and ***:GEPIA database showed that NUDT5 expression was significantly increased in GBM *** the expression of NUDT5 in GBM cells significantly suppressed the viability,proliferation,invasion,migration,and glycolysis of GBM ***,TRIM47 was highly expressed in GBM cells and interacted with *** of TRIM47 partially reversed the inhibitory effect of NUDT5 downregulation on the proliferation,metastasis,and glycolysis of GBM ***:NUDT5 promotes the growth,metastasis,and Warburg effect of GBM cells by upregulating *** NUDT5 and TRIM47 can be used as targets for GMB treatment.

关键词： Glioblastoma multiforme NUDT5 TRIM47 Growth Metastasis Warburg effect

Residual levels and health risk assessment of trace metals in Chinese resident diet

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Journal of Environmental Sciences 2024年第2期136卷 451-459页

作者： Yubing Dai Shuai Sun rong Cao Haijun zhang Jiping Chen Ningbo Geng CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Shenyang Pharmaceutical University Shenyang 110016China University of Chinese Academy of Sciences Beijing 100049China

Large-scale metal contamination across the food web is an intractable problem due to increasing pollutant emissions,atmospheric transport,and dry and wet deposition of *** present study focus on several trace metals that are rarely studied but have special toxicity,including tin(Sn),antimony(Sb),gold(Au),hafnium(Hf),palladium(Pd),platinum(Pt),ruthenium(Ru),tellurium(Te)and iridium(Ir).We investigated trace metals residues and distribution characteristics,and further evaluated the potential health risks from major daily food intakes in 33 cities in ***,Sb,Ir,Hf,and Au were frequently detected in food samples with the concentrations ranged from ND(not detected)to 24.78μg/kg ww(wet weight).Eggs exhibited the highest residual level of all detected metals(13.70±14.70μg/kg ww in sum),while the lowest concentrations were observed in vegetables(0.53±0.17μg/kg ww in sum).Sn accounting for more than 50%of the total trace metals concentration in both terrestrial and aquatic animal origin *** terrestrial plant origin foods,Sn and Ir were the most abundant *** and Au were the most abundant elements in egg *** addition,Sb and Ir showed a clear trophic dilution effect in terrestrial environments,while in aquatic ecosystems,Sn,Hf,and Au exhibited obvious trophic amplification *** calculated average estimated daily intake(EDI)via food consumption in five regions of China was 0.09μg/(kg·day),implying the health risk of aforementioned elements was acceptable.

关键词： Trace metals Accumulation characteristics Dietary exposure Estimated daily intake(EDI)

Facile Synthesis of Polyisothioureas via Alternating Copolymerization of Aziridines and Isothiocayanates

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Chinese Journal of Polymer Science 2024年第3期42卷 292-298,I0005页

作者： Hao-Tian zhang ming-Xin Niu Qi zhang Chen-Yang Hu Xuan Pang Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Department of Materials Science and Engineering Jilin UniversityChangchun 130025China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China

Isothiourea is an important class of sulfur-containing molecules showing unique catalytic and biological activities. As such,polyisothiourea is envisioned to be an interesting type of polymer that potentially exhibits a number of interesting properties. However, there is no access to synthesizing well-defined polyisothiourea, and currently isothiourea-containing polymers are mainly prepared by immobilizing onto other polymer's side chain. Herein, we report the first facile synthesis of polyisothioureas via alternating copolymerization of aziridines and isothiocayanates. Mediated by the catalytic system of phosphazene superbases/alcohol, a broad scope of aziridines and isothiocayanates could be transformed into polyisothioureas with adjustable substitutions(11 examples). The structures of obtained polyisothioureas were fully characterized with ^(1)H-NMR, ^(13)C-NMR, and ^(1)H-^(13)C HMBC NMR. Moreover, the polyisothioureas show tunable thermal properties depending on substitutions on the isothiourea linkages. The novel structure of these polyisothioureas will enable a powerful platform for the discovery of nextgeneration functional plastics.

关键词： Polyisothioureas Alternative copolymer Aziridines Isothiocayanates

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民间儒学与官方儒学

天津师范大学学报（社会科学版） 2012年第1期32卷 20-23页

作者：张荣明南开大学中国社会史研究中心

大体说来,传统儒学有两种形态,一种是在野的民间形态,另一种是在朝的官方形态,这两种形态的儒学既有共性也有差异。其共性是,重视人和人际关系,强调社会道德秩序;其差异性是,民间儒学主要存在于社会转型期,官方儒学存在于非转型期。弄... 详细信息

大体说来,传统儒学有两种形态,一种是在野的民间形态,另一种是在朝的官方形态,这两种形态的儒学既有共性也有差异。其共性是,重视人和人际关系,强调社会道德秩序;其差异性是,民间儒学主要存在于社会转型期,官方儒学存在于非转型期。弄清儒学的这两种不同形态,对于认识当下儒学的地位和作用,不无借鉴意义。

关键词：民间儒学官方儒学官方意识形态儒教

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儒教、国民宗教与政治神学

天津师范大学学报（社会科学版） 2010年第3期30卷 29-32,37页

作者：张荣明南开大学中国社会史研究中心

20世纪80年代,在中国发生了一场关于"儒教"问题的学术争论。20世纪60年代,在西方发生了一场关于"国民宗教"的学术争论。尽管这两场争论发生的时间、空间不同,但涉及的问题却类似,即是否存在一种以政治秩序和政治制度为指向的宗教。就功... 详细信息

20世纪80年代,在中国发生了一场关于"儒教"问题的学术争论。20世纪60年代,在西方发生了一场关于"国民宗教"的学术争论。尽管这两场争论发生的时间、空间不同,但涉及的问题却类似,即是否存在一种以政治秩序和政治制度为指向的宗教。就功能而言,"儒教"和"国民宗教"都是与生命神学截然不同的政治神学。

关键词：儒教国民宗教政治神学

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思想史研究的三个根本问题

湖南大学学报（社会科学版） 2010年第6期24卷 5-9页

作者：张荣明南开大学中国社会史研究中心天津300071

在思想史研究中,应该注意区分三大关系:间接研究对象与直接研究对象的关系,获得具体知识与获得抽象知识的关系,实证方法与理论方法的关系。这三个方面彼此紧密相关,构成思想史研究基本理论的有机整体。处理好这三对关系,对思想史研究甚... 详细信息

在思想史研究中,应该注意区分三大关系:间接研究对象与直接研究对象的关系,获得具体知识与获得抽象知识的关系,实证方法与理论方法的关系。这三个方面彼此紧密相关,构成思想史研究基本理论的有机整体。处理好这三对关系,对思想史研究甚至历史研究有重要的学术意义。

关键词：思想史研究史学理论史学方法

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魏晋思想的世俗与超俗

天津师范大学学报（社会科学版） 2013年第2期33卷 6-9页

作者：张荣明南开大学中国社会史研究中心

魏晋思想的特色,是作为官方意识形态的儒家思想衰落,以及多元思想的兴起。新兴的多元思想略有两端:一端是世俗的拜金主义和纵欲主义;另一端是超俗的现实批判和隐逸思潮。魏晋玄学仅仅反映了这一宏观思想格局的一个侧面,而非全部。造成... 详细信息

魏晋思想的特色,是作为官方意识形态的儒家思想衰落,以及多元思想的兴起。新兴的多元思想略有两端:一端是世俗的拜金主义和纵欲主义;另一端是超俗的现实批判和隐逸思潮。魏晋玄学仅仅反映了这一宏观思想格局的一个侧面,而非全部。造成魏晋思想状况的根本原因是社会经济、政治重心的下移和皇权的衰弱,这种思想格局又促发了士人宗教思潮。在特定的文化中,经济重心下移和政治重心下移、拜金主义和纵欲主义、现实批判和士人隐逸,这几种社会现象之间存在着彼此联系,共同构成一个有机的文化整体。

关键词：魏晋思想魏晋玄学拜金主义隐逸思潮

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加快发展现代职业教育助推新型城镇化建设

职业技术教育 2014年第25期35卷 5-7页

作者：张榕明中华职业教育社北京100075

当前和今后一段时期,新型城镇化是我国经济社会可持续发展的重大战略任务。加快发展现代职业教育是新型城镇化的基本内容和必要条件,在推进新型城镇化建设中肩负着促进农村富余劳动力有序转移、助推产业结构优化升级、传播城市文明、增... 详细信息

当前和今后一段时期,新型城镇化是我国经济社会可持续发展的重大战略任务。加快发展现代职业教育是新型城镇化的基本内容和必要条件,在推进新型城镇化建设中肩负着促进农村富余劳动力有序转移、助推产业结构优化升级、传播城市文明、增加居民收入等重要任务。为有效发挥这些职能,职业教育要着重做好如下工作:加强一体化设计,推动职业教育和城镇化的同步良性互动发展;完善新市民就业培训体系,加快形成促进农村劳动力转移就业的长效机制;增强服务意识,切实提高人才培养质量和水平。

关键词：现代职业教育新型城镇化农村劳动力转移

Achieving laparoscopic anatomic resection for hepatocellular carcinoma by fluorescence guided positive staining of hepatic cone unit

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Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 406-411页

作者： Jun-Fang Deng Chuan-Hui Peng Yu zhang Xiao-Feng Xu rong-Liang Tong Zheng-Long Zhai Di-Yu Chen Cheng zhang Li-ming Wu Jian Wu Division of Hepatobiliary Pancreatic Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Laparoscopic anatomical liver resection has been increasingly reported worldwide,but how to demarcate the resection planes is technically challenging[1].Positive staining technique with intraoperative indocyanine green(ICG)-fluorescence imaging has been introduced as an effective tool for real-time intraoperative guidance[2].Liver anatomy is ***,liver is composed of 9 segments,each is composed of two to three subsegments,and each subsegment contains several hepatic cone units.A hepatic cone unit is dominated by a tertiary or quaternary hepatic pedicles[3].

关键词： hepatic resection anatomy

A Mass-Preserving Characteristic Finite Difference Method For Miscible Displacement Problem

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Advances in Applied Mathematics and Mechanics 2024年第1期16卷 164-180页

作者： Jiansong zhang Yue Yu rong Qin Zhaohui Liu Department of Applied Mathematics China University of PetroleumQingdaoShandong 266580China

In this article,a new characteristic finite difference method is developed for solving miscible displacement problem in porous *** new method combines the characteristic technique with mass-preserving interpolation,not only keeps mass balance but also is of second-order accuracy both in time and *** results are presented to confirm the convergence and the accuracy in time and space.

关键词： The method of characteristics mass-preserving finite difference miscible displacement problem