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The structured total least squares algorithm research for passive location based on angle information

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Science in China(Series F) 2009年第6期52卷 1043-1054页

作者： WANG Ding zhang li WU ying Institute of Information Engineering PLA Information Engineering University Zhengzhou 450002 China

Based on the constrained total least squares （CTLS） passive location algorithm with bearing-only measurements, in this paper, the same passive location problem is transformed into the structured total least squares （STLS） *** solution of the STLS problem for passive location can be obtained using the inverse iteration *** also expatiates that both the STLS algorithm and the CTLS algorithm have the same location mean squares error under certain ***, the article presents a kind of location and tracking algorithm for moving target by combining STLS location algorithm with Kalman filter （KF）.The efficiency and superiority of the proposed algorithms can be confirmed by computer simulation results.

关键词： passive location angle information least squares total least squares constrained total least squares structured total least squares Kalman filter singular value decomposition QR decomposition

Group separation of coal components and new ideas of coal utilization as petroleum

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Mining Science and Technology 2009年第5期19卷 636-641页

作者： QIN Zhi-hong HOU Cui-li CHEN Juan zhang li-ying MA Jie-qiong School of Chemical Engineering and Technology China University of Mining ＆ Technology Xuzhou Jiangsu 221116 China

Four different groups of components were separated from coal under mild conditions of extraction and stripping process. Within these groups, and with pre-separation, individual utilization of all coal components can be realized, similar to petroleum components and enhance the inherent value and utilization value of coal, as well as increase environmental benefits. The characteristics of each component were analyzed with measurements by FTIR, GC/MS, TEM and the establishment of caking properties. The results show that coal can be separated into residues, ultra-pure coal, asphaltene components and light components by adding solvents for stripping into the CS2/NMP mixed extraction solution. Those four groups of components present great differences in the presence of carbon and hydrogen elements, in the structure of functional groups, in their macroscopic structure and micro-morphology and caking properties. Every component possesses its own inherent values and approaches. A new idea of coal processes and utilization, similar to the use of petroleum is proposed.

关键词： coal group components separation similarity to petroleum process and utilization

Fine Mapping and Cloning of the Grain Number Per-Panicle Gene (Gnp4) on Chromosome 4 in Rice (Oryza sativa L.)

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Agricultural Sciences in China 2011年第12期10卷 1825-1833页

作者： zhang Zhan-ying li Jin-jie YAO Guo-xin zhang Hong-liang DOU Hui-jing SHI Hong-li SUN Xing-ming li Zi-chao Key Laboratory of Crop Heterosis and Utilization Ministry of Agriculture/Beijing Key Laboratory of Crop Genetic Improvement ChinaAgricultural University Beijing 100193 P.R.China

Grain number per-panicle is one of the most important components for rice yield. Spikelets on the primary and secondary branches determine the grain number per-panicle in rice. In this study, we identified a natural mutant, gnp4, lack of lateral spikelet on the secondary branches in the field condition. In addition, the Gnp4 and Lax1-1 double mutant showed dramatically reduced secondary branches and spikelets in panicle at reproductive stage, and tillers at vegetative stage. By map-based cloning approach, and using four F2 segregating populations, the Gnp4 gene was finally mapped to a 10.7-kb region on the long arm of chromosome 4 in rice. In this region, only one gene was predicted, and genomic DNA sequencing of the 10.7-kb region showed no nucleotide differences between the mutant and wild type. Interestingly, we found that the methylation level of several cytosines in the promoter CpG islands region of the predicted gene in gnp4 were different from the wild type. Thus, we propose that the DNA methylation changes at these sites may induce to decrease expression level of Gnp4, consequently, resulting in phenotypic variation.

关键词： rice gnp4 laxl-1 grain number per-panicle methylation

The Herbicidal Activity of Mutant Isolates from Botrytis cinerea

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Agricultural Sciences in China 2006年第8期5卷 622-628页

作者： zhang Jin-lin zhang li-hui liU ying-chao MA Juan li Chuan DONG Jin-gao Mycotoxin Laboratory Hebei Agricultural University Baoding 071001 P.R.China

Fifteen mutant isolates were obtained by ultraviolet mutation from parent isolate Botrytis cinerea BC-4. Among them three mutant isolates, BC4-1, BC4-2, and BC4-15, showed strong herbicidal activity. BC4-1 showed maximum herbicidal activity for inhibition of germination and growth of Digitaria sanguinalis L. and Arnaranthus retroflexus L. The results also showed that herbicidal activity was influenced by differing pH of PD media, with pH value of 4.0 being the optimum. The crude toxin was extracted using chloroform, petroleum ether, and ethyl acetate, respectively, and the ethyl acetate extracts showed the strongest inhibitory activity on the germination and growth of D. sanguinalis L. and A. retroflexus L. Using HPLC, one fraction with an absorption peak at 271 nm was separated from the crude toxin. This fraction could strongly inhibit the growth of D. sanguinalis L. at a concentration of 100 mg L^-1 and could completely inhibit the seed germination of D. sanguinalis L. and A. retroflexus L. at a concentration of 50 mg L^-1 .

关键词： Botrytis cinerea toxin ultraviolet mutation herbicide activity separation and purification

Asymmetric synthesis of pedamide using I_2-induced heterocyclization to construct the skeleton

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Chinese Chemical Letters 2009年第7期20卷 775-778页

作者： De Gang liu Ji Jun Xue Zhi Xiang Xie li Ping Wei Hua Bing zhang ying li State Key Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 730000 PR China

An alternative approach to synthesize pedamide, a key building block of pederin was described. Iodine-induced asymmetric heterocyclization was used as the key step to construct the skeleton, a tetrahydropyran ring with three chiral centers. Brown＇s asymmetric allylation and Lewis acid-mediated allylation were investigated to introduce chains and chiral alcohols. Sharpless dihydroxylation decorated the side chain. And high optically pure target was obtained by removing the epimers formed in these reactions on column chromatography.C2009 Ji Jun Xue. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All fights reserved.

关键词： Synthesis Pedamide Pederin

Solubilization of small molecules from coal and the resulting effects on the pore structure distribution

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Mining Science and Technology 2009年第6期19卷 761-768页

作者： QIN Zhi-hong JIANG Chun HOU Cui-li li Xing-shun zhang li-ying CHEN Juan JIANG Bin School of Chemical Engineering and Technology China University of Mining ＆ Technology Xuzhou Jiangsu 221116 China Lu＇an Mining Industry Group Changzhi Shanxi 046204 China

The solubilization of small molecules from coal by solvent extraction and the resulting effects on the pore distribution of a low rank coal were studied. Samples were extracted, in succession, with petroleum ether and with CS2. Extract and residue fractions collected during the solubilization process were analyzed by FTIR and by surface area and porosimetry. The results show that an obvious inflection point exists that allows separating the dissolution sequence into stages. Small molecules are first extracted from the free state, then molecules trapped in micropores are extracted and, finally, molecules trapped in the coal-matrix network are extracted. This is indicated from the extraction yield curves. Chain-like carbonyl compounds, -OH (or -NH) containing compounds that are hydrogen bonded and phenolics dominate the petroleum ether extracts. Chain-like carbonyl components and ether compounds (aliphatic ethers and aromatic ethers) dominate the CS2 extracts. A solvent dissolution mechanism and the effect of small molecule extraction on the pore structure are put forward. Diffusion, dissolution, pore opening, pore shrinking or even collapsing caused by swelling, creating of new micropores, pore opening and, finally, colloidallization of some micropores occurs. In the later stages of the extraction the internal structure of the coal is colloidallized due to swelling and the pore number or volume is greatly reduced.

关键词： coal fractional extraction FTIR distribution of pores

Contribution of Ambient Air Pollution on Risk Assessment of Type 2 Diabetes Mellitus via Explainable Machine Learning

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Biomedical and Environmental Sciences 2023年第6期36卷 557-560页

作者： DING Zhong Ao zhang li ying li Rui ying NIU Miao Miao ZHAO Bo DONG Xiao Kang liU Xiao Tian HOU Jian MAO Zhen Xing WANG Chong Jian Department of Epidemiology and Biostatistics College of Public HealthZhengzhou UniversityZhengzhou 450001HenanChina Department of Software Engineering School of Computer and Artificial IntelligenceZhengzhou UniversityZhengzhou 450001HenanChina Department of Statistics University of Illinois at Urbana-ChampaignChampaignU.S.A NHC Key Laboratory of Prevention and Treatment of Cerebrovascular Diseases Zhengzhou 450001HenanChina

Type 2 diabetes mellitus(T2DM)is recognized as a heterogeneous and complicated disease that is able to influence individuals at various life stages[1].Apart from traditional predictors such as age,family history of diabetes,body mass index,and so on,ambient air pollution is also shown to increase the risk of T2DM in previous studies.

关键词： T2DM Diabetes diabetes

Three Important Transcription Factors Related to lipogenesis and Adipogenesis in Mammal

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Journal of Northeast Agricultural University(English Edition) 2010年第3期17卷 62-75页

作者： zhang ying li Hui College of Animal Sciences and Technology Northeast Agricultural University Harbin 150030 China

lipid metabolism and adipocyte differentiation are reglulated by networking of transcription factors. It is generally known that three factors, peroxisome proliferator-activated receptor y （PPARγ）, CCAAT/element-binding protein a （C/EBPa） and sterol regulatory element binding protein-1 （SREBP1）, play fundamental roles in metabolic pathways. And they are also important in adipocyte differentiation. Expressions of these factors are regulated by some compounds such as fatty acids or some steroid hormones （insulin） which is stimulated by the nutritional level. Furthermore, these factors are related to some metabolic diseases including type II diabetes and obesity, Lots of researches have focused on relationships between the factors and the genetic diseases. Different functions of factors on inducing the adipocyte differentiation are other hot spots according to previous studies. This paper summarized these studies and gave a limpid description of structures and functions of these genes.

关键词： PPARγ C/EBPa SREBP1 lipogenesis adipogenesis

Identification of genes upregulated by recombinant interferon-alpha in HepG2 cells by suppressive subtractive hybridization analysis

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Hepatobiliary & Pancreatic Diseases International 2007年第3期6卷 290-293页

作者： Qu, Jian-Hui Cheng, Jun zhang, ling-Xia zhang, li-ying Zhong, Yan-Wei liu, Yan Wang, lin Dai, Jiu-Zeng Xu, Dong-Ping Beijing Ditan Hosp Inst Infect Dis Beijing 100011 Peoples R China PLA 302 Hosp Gene Therapy Res Ctr Inst Infect Dis Beijing 100039 Peoples R China

BACKGROUND: Interferon-alpha (IFN-alpha) is an important cytokine with multiple functions, but the target genes transactivated by IFN-alpha remain largely unknown. A study of such genes will help to understand the mechanism of function of IFN-alpha. To isolate the gene transcripts specifically upregulated by IFN-alpha in HepG2 cells, we conducted suppressive subtractive hybridization (SSH) analysis. METHODS: SSH was used to analyze the target genes transactivated by recombinant IFN-alpha protein, and a subtractive cDNA library was constructed from HepG2 cells treated with recombinant IFN-alpha (rIFN-alpha, 2000 IU/ml) for 16 hours as tester, and cells not treated with rIFN-alpha as driver. The SSH PCR products from the library were cloned into pGEM-T easy vector and with BLASTX, the positive clones were randomly selected, sequenced and compared to the database in GenBank of the 35 differentially expressed gene fragments from the library, 6 clones showed significant homology to other known proteins. RESULTS: The subtractive cDNA library of genes upregulated by IFN-alpha was constructed successfully, rIFN-alpha upregulated the expression of the RAN binding protein 5 (RANBP5), NADH dehydrogenase, exosome component 3 (EXOSC3), zinc finger RNA binding protein, Dickkopf homolog 1 (DKK1) and acetyl-coenzyme A acetyltransferase 2 (ACAT2). CONCLUSIONS: These results suggest that rIFN-alpha can upregulate the expression of important genes to exert its functions, and provide new clues for discovering the molecular mechanisms of action of IFN-alpha.

关键词： interferon-alpha suppressive subtractive hybridization transactivation