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Genes & Diseases 2024年第1期11卷 19-22页

作者： Zhenhai Li Wenchao Xu feng Chen jun zhang Wei-Guo Zhu Guangdong Key Laboratory of Genome Instability and Human Disease Prevention Department of Biochemistry and Molecular BiologyShenzhen University School of MedicineShenzhenGuangdong 518055China School of Pharmaceutical Sciences Shenzhen University Health Science CenterShenzhenGuangdong 518055China Base for International Science and Technology Cooperation:Carson Cancer Stem Cell Vaccines R&D Center International Cancer CenterShenzhen University Health Science CenterShenzhenGuangdong 518055China Shenzhen Bay Laboratory Shenzhen University School of MedicineShenzhenGuangdong 518055China Marshall Laboratory of Biomedical Engineering Shenzhen University School of MedicineShenzhenGuangdong 518055China

Etoposide is widely used for cancer chemotherapy in the ***,long-term etoposide treatment can lead to adverse effects or drug *** improve the situation,we evaluated the therapeutic efficiency of etoposide combined with inhibitors of bromodomain and extraterminal(BET)family proteins,which have recently emerged as novel anti-cancer targets due to their critical roles in cancer ***,we showed BRD4,one of the main targets of BET inhibitors,was involved in DNA damage response(DDR)via the homologous recombination(HR)repair pathway.

关键词： etoposide damage cancer

基于数据挖掘技术探讨针刺治疗卒中后下肢痉挛的选穴规律

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广州中医药大学学报 2024年第6期41卷 1522-1529页

作者：丛珊张军风李虹王猛闫隆钱玉林于涛天津中医药大学第一附属医院/国家中医针灸临床医学研究中心天津300380 天津中医药大学研究生院天津301617

【目的】基于数据挖掘技术探讨针刺治疗卒中后下肢痉挛的选穴规律。【方法】通过计算机检索中国知网期刊全文数据库(CNKI)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊全文数据库(VIP)、美国生物医学信息检索系统(PubMed)、荷... 详细信息

【目的】基于数据挖掘技术探讨针刺治疗卒中后下肢痉挛的选穴规律。【方法】通过计算机检索中国知网期刊全文数据库(CNKI)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊全文数据库(VIP)、美国生物医学信息检索系统(PubMed)、荷兰医学文摘(EMbase)、科学网(Web of Science)等数据库,筛选符合纳入标准的文献建立数据库。通过Microsoft Excel 2016、IBM SPSS Statistics 21、IBM SPSS Modeler 18.0软件对数据进行描述性分析、聚类分析和关联规则分析。【结果】(1)共纳入68条针刺处方,涉及腧穴100个,总使用频次536次;(2)腧穴使用频次排前5位的分别是阳陵泉、足三里、悬钟、丘墟、三阴交;(3)核心腧穴配伍为阳陵泉-悬钟,并得到5个有效聚类群,分别为申脉-照海、委中-昆仑、血海-环跳-丰隆-足三里、太溪-阴陵泉-三阴交、解溪-太冲-悬钟-丘墟-阳陵泉。【结论】通过数据挖掘发现,针刺治疗卒中后下肢痉挛多以阳陵泉、足三里、悬钟、丘墟、悬钟为核心,优先考虑足三阳经、五输穴的应用,辨证论治、随证加减,可为临床治疗卒中后下肢痉挛提供参考依据。

关键词：针刺脑卒中下肢痉挛足三阳经五输穴选穴规律数据挖掘

Bifunctional core–shell co-catalyst for boosting photocatalytic CO_(2) reduction to CH_(4)

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Nano Research 2024年第3期17卷 1259-1266页

作者： Fangxu Dai Mingming zhang Jishu Han Zhenjiang Li Shouhua feng jun Xing Lei Wang Key Laboratory of Eco-chemical Engineering Ministry of EducationCollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China College of Materials Science and Engineering Qingdao University of Science and TechnologyQingdao 266042China College of Environment and Safety Engineering Qingdao University of Science and TechnologyShandong Engineering Research Center for Marine Environment Corrosion and Safety ProtectionQingdao 266042China

Solar-light-driven CO_(2) reduction CO to CH_(4) and C2H6 is a complex process involving multiple elementary reactions and energy ***,achieving high CH_(4) activity and selectivity remains a significant ***,we integrate bifunctional Cu2O and Cu-MOF(MOF=metal-organic framework)core–shell co-catalysts(Cu2O@Cu-MOF)with semiconductor TiO_(2).Experiments and theoretical calculations demonstrate that Cu2O(Cu+facilitates charge separation)and Cu-MOF(Cu2+improves the CO_(2) adsorption and activation)in the core–shell structure have a synergistic effect on photocatalytic CO_(2) reduction,reducing the formation barrier of the key intermediate*COOH and**** photocatalyst exhibits high CH_(4) yield(366.0μmol·g^(-1)·h^(-1)),efficient electron transfer(3283μmol·g^(-1)·h^(-1))and hydrocarbon selectivity(95.5%),which represents the highest activity of Cu-MOF-based catalysts in photocatalytic CO_(2) reduction *** work provides a strategy for designing efficient photocatalysts from the perspective of precise regulation of components.

关键词： bifunctional co-catalyst core–shell photocatalytic CO_(2)reduction

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机场停机位分配问题研究现状与展望

航空计算技术 2024年第4期54卷 130-134页

作者：潘肖然胡荣邓松武孙娇娇张军峰南京航空航天大学江苏南京211000 韶关丹霞机场有限公司广东韶关512000

为提高机场场面资源利用效率,大量文章研究停机位分配问题的优化模型与求解算法。首先,概述了停机位分配问题概念。其次,从旅客、机场、航空公司和鲁棒性等不同维度,梳理了停机位分配问题优化目标的研究现状,并归纳了停机位分配问题的... 详细信息

为提高机场场面资源利用效率,大量文章研究停机位分配问题的优化模型与求解算法。首先,概述了停机位分配问题概念。其次,从旅客、机场、航空公司和鲁棒性等不同维度,梳理了停机位分配问题优化目标的研究现状,并归纳了停机位分配问题的约束条件。从数学规划法、智能优化法两个维度综述了停机位分配问题的求解算法,并比较了不同算法优缺点。最后,从考虑交互关系的多目标优化、实现动态实时分配、多资源联合分配、创新优化算法和考虑不确定因素五个方面展望了停机位分配问题研究的发展趋势。

关键词：停机位分配优化目标约束条件算法设计联合分配

Two-Flux Colliding Plane Waves in String Theory

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Communications in Theoretical Physics 2005年第3X期44卷 463-472页

作者： CHEN Bin zhang jun-feng Department of Physics Peking University Beijing 100871 China Department of Mathematics Capital Normal University Beijing 100037 China

We construct the two-flux colliding plane wave solutions in higher-dimensional gravity theory with dilaton,and two complementary fluxes. Two kinds of solutions have been obtained: Bell-Szekeres (BS) type and homogeneous type. After imposing the junction condition, we find that only the BS type solution is physically well-defined. Furthermore, we show that the future curvature singularity is always developed for our solutions.

关键词：平面波碰撞弦理论引力理论曲率

Dielectric and energy storage properties of PbO–SrO–Nb_(2)O_(5)–Na_(2)O–Si thin films by annealing

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Rare Metals 2024年第1期43卷 351-355页

作者： Fei-Hu Tan Qing-Meng zhang feng Wei Hong-Bin Zhao Xiao zhang jun Du State Key Laboratory of Advanced Materials for Smart Sensing General Research Institute for Nonferrous MetalsBeijing 100088China Advanced Electronic Materials Institute General Research Institute for Nonferrous MetalsBeijing 100088China

Dielectric and energy storage properties of PbOSrO-Na_(2)O-Nb_(2)O_(5)-SiO_(2)(PSNNS) thin films with annealing temperature from 700 to 850 ℃ were investigated by measuring their capacitance-electric filed curve and hysteresis *** results show that the highest dielectric constant and energy density are 81.2 and 17.0 J·cm^(-3),respectively,which is obtained in the sample with annealing temperature of 800 ℃.Annealed from 700 to800 ℃,the dielectric constant and energy storage performance of PSNNS films are continuously ***,with annealing temperature up to 850 ℃,their dielectric constant decreases,which might be related with the removal of interfacial defects as a function of annealing *** is one of the causes of space charge phenomenon,resulting in the increase in dielectric ***,the micro structure analysis by X-ray diffraction(XRD) and transmission electron microscope(TEM) indicates that the change of crystallization phase and interfacial polarization takes responsibility to the results.

关键词： Thin film Pulse laser deposition Annealing temperature Energy storage density

Wavefield Separation of Distributed Acoustic Sensing Vertical Seismic Profile Data Based on Multichannel Vector Median Filtering

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Journal of Earth Science 2024年第2期35卷 712-716页

作者： Zijuan Ma jun Lu feng zhang Pinbo Ding Zhidong Cai Key Laboratory of Intraplate Volcanoes and Earthquakes Ministry of EducationChina University of GeosciencesBeijing 100083China College of Geophysics China University of PetroleumBeijing 102249China New Resources Geophysical Exploration Division BGP Inc.CNPCZhuozhouHebei 072751China

INTRODUCTION Distributed acoustic sensing(DAS)is a novel and popular technology for vertical seismic profile(VSP)data acquisition because of its many advantages,including full vertical coverage,high sampling density,low cost,and resistance to stressors(high temperature and pressure).The current industrial application of DAS in borehole exploration acquires single-mode *** records strain rates,which are then converted to particle velocities by the modem before being written to the disk.

关键词： Seismic Vertical borehole

Recent advances in vacancy engineering for reliable lithiumsulfur batteries

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Rare Metals 2024年第2期43卷 455-477页

作者： Wen-Dong Liu Xiao Tang jun-An feng Chao-Yue zhang Hao Liu Chuan Shi Xiao-Xian Zhao Jian-jun Song College of Physics School of Chemistry and Chemical EngineeringQingdao UniversityQingdao266071China Faculty of Science Centre for Clean Energy TechnologySchool of Mathematical and Physical SciencesUniversity of Technology SydneySydneyNSW2007Australia Department of Chemistry College of ScienceHebei Agricultural UniversityBaoding071001China

The high-energy-density and low-cost features endow lithium-sulfur batteries with broad application ***,many drawbacks,especially the detrimental shuttle effect,have hindered the further development of *** response,a lot of new structures have been applied to suppress the shuttle effect and promote the development of ***,vacancy engineering has gained the attention of researchers due to its unique electronic *** review aims to analyze the application of vacancy engineering in ***,the electrochemistry of LSBs has been systematically discussed and the existing challenges as well as improvement tactics of LSBs have also been ***,the preparation methods and characterization technologies of various vacancies are summarized,including oxygen vacancies,sulfur vacancies,selenium vacancies,other anion vacancies,cation vacancies,*** latest applications of vacancy engineering in LSBs are also summarized in this ***,some prospects and insights for further investigation and practical application of vacancy engineering in LSBs are put forward.

关键词： Lithium-sulfur batteries(LSBs) Defects Vacancy engineering Electronic structure Shuttle effect

Prediction for permeability index of blast furnace based on VMD-PSO-BP model

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Journal of Iron and Steel Research(International) 2024年第3期31卷 573-583页

作者： Xiao-jie Liu Yu-jie zhang Xin Li Zhi-feng zhang Hong-yang Li Ran Liu Shu-jun Chen School of Metallurgy and Energy North China University of Science and TechnologyTangshan 063210HebeiChina Chengde Branch HBIS Group Co.Ltd.Chengde 067000HebeiChina

The permeability index is one of the important production indicators to monitor the operation of blast *** is crucial to grasp the trends of changes in the new permeability index in *** the complex vibration spectrum of the permeability index,a prediction model of the permeability index based on the VMD-PSO-BP(variational mode decomposition-particle swarm optimization-back propagation)method was ***,the key factors that affect the permeability index of blast furnace were studied from multiple ***,the permeability index was divided into multiple sub-modes based on the difference of frequency bands by the VMD algorithm,and a PSO-BP prediction model was established for each ***,the prediction results of each sub-mode were summed to obtain the final *** results show that the composite prediction accuracy by using the VMD algorithm is 3%higher than that of the traditional prediction method,which has better applicability.

关键词： Big data-Blast furnace Air permeability Variational mode decomposition Particle swarm optimization Back propagation Model prediction

Design and identification of a double-acting piezoelectric-hydraulic hybrid actuator

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Chinese Journal of Aeronautics 2024年第3期37卷 456-467页

作者： junjian zhang Zhihua feng Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes University of Science and Technology of ChinaHefei 230026China

Traditional single-acting piezoelectric-hydraulic hybrid actuators usually have the problem of inertial force caused by flow pulsation of the liquid,which degrades their output *** suppress or solve the associated inertial force and enhance its output capabilities,this paper proposes a new type of double-acting piezoelectric-hydraulic hybrid actuator with four check valves acting as mechanical *** new hybrid actuator was fabricated and its output performance was *** the voltage is 700 Vp-pand the bias pressure is 2 MPa,the pulsation ratesδof the new actuator at 400 Hz,500 Hz and 600 Hz are 2.29,2.08 and 1.78,respectively,whileδof the single-acting hybrid actuator under the same conditions are 10.98,11.05 and ***,the liquid pulsation rate of the new hybrid actuator is significantly reduced,which is beneficial for improving the flow uniformity and weakening the influence of inertial force on the hybrid *** strategy ultimately leads to a maximum no-load velocity of 168.1 mm/s at 600 Hz and a maximum blocking force of 141 N at 450 Hz for the new hybrid *** addition,this strategy has the potential to be used in other electrohydrostatic actuators to improve their performance.

关键词： Double-acting Flow pulsation Inertial force Piezoelectric actuators Piezoelectric devices Piezoelectric hydraulic actuation Piezoelectric pump