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3. Nerve: A Three-Dimensional Reconstruction System for Peripheral Nerves

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3D Nerve: A Three-Dimensional Reconstruction System for Peri...

A multicenter uroflowmetry study of healthy women in China

2.08 IEEE International Symposium on IT in Medicine and Education(ITME 2.08)

作者： Ping Hu 1 2.Shuisheng Xie 1 2.Juan Ge 1 2.Liyan Liu 1 2.Shaorong wang 1 2.Fucang Jia 1 2.Zongkai Lin 1 2.Hua Li 1 2.Kuo Sun 3.Zenggan Chen 3.jian {2. 3.1.National Research Center for Intelligent Computing Systems Institute of Computing technology Chinese academy of {13. beijing 100190 China 2.graduate university of Chinese academy of {13. beijing 100049 China 3.Zhongshan Hospital Fudan university Shanghai 2.003.0}China

Repair and regeneration of injured peripheral nerves have always been a focus in the field of *** nerve atlas contains only two-dimensional information and can’t display the real cross and recombination process of nerve bundles in its whole *** solve this problem,a system,3. Nerve,is proposed for the 3. reconstruction of peripheral *** image registration,image segmentation,contour correspondence and surface reconstruction process,this system successfully represents the topographic anatomy of every nerve fascicle and its relationship with the nicety localization information of sense fibers and motor ones in arbitrary *** is a great help for clinical peripheral nerve repair and 3. peripheral nerve teaching.

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Chinese Medical Journal 2024年第10期137卷 1225-1227页

作者： Xiaodong Liu Lingfeng Meng Jiawen wang Tianming Ma Benkang Shi Hai Huang Qingwei wang Min Chen Limin Liao Hong Shen Zhongqing Wei Yuansong Xiao Tiejun Pan {2. Ren Peng {3. Xiaojun Tian Yaoguang {3. Department of Urology Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China graduate school of Peking Union Medical College Beijing 100730China Department of Urology Qilu HospitalShandong UniversityJinanShandong 250013China Department of Urology SUN YAT-SEN Memorial HospitalGuangzhouGuangdong 510235China Department of Urology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450003China Department of Urology Tongji HospitalTongji Medical College of Huazhong University of Science and TechnologyWuhanHubei 430030China Department of Urology China Rehabilitation Research CenterBeijing 100068China Department of Urology West China HospitalChengduSichuan 610041China Department of Urology The Second Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210011China Department of Urology General Hospital of Southern Theatre CommandGuangzhouGuangdong 510010China Department of Urology General Hospital of Central Theatre CommandWuhanHubei 430071China Department of Urology China-Japan Friendship HospitalBeijing 100029China Department of Urology Beijing Chao-Yang HospitalBeijing 100027China Department of Urology Peking University Third HospitalBeijing 100191China

Uroflowmetry is an uroflow measurement technique used to record the voided volume(VV)and flow rate,which can help clinicians objectively evaluate lower urinary tract ***,few uroflowmetry studies have focused on the female population,[1]especially on the uroflow curve standard ***,we sought to establish dependable uroflow reference values and nomograms for Chinese women and to evaluate the relationship between uroflow patterns and demographic data.

关键词： function. flowmetry analysis.

Changes of cell morphology and cytoskeleton organization in a hypogeomagnetic field

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Changes of cell morphology and cytoskeleton organization in ...

DEAD-box helicase 17(DDX17)protects cardiac function by promoting mitochondrial homeostasis in heart failure

2.11年空间生命与生命起源暨航天医学工程学术研讨会

作者： Wei-chuan Mo~(1,3.,Dong-liang wang~2.Zi-jian {2.~(1,3.,Ying Liu~(1,3., Rong-qiao He~(1,3. 1 State Key Laboratory of Brain and Cognitive science,Institute of Biophysics,Chinese academy of sciences,15 Datun Road,Chaoyang District,beijing 100101,China 2.National Center for Nanoscience and technology,Chinese academy of sciences,11 Zhongguancun Beiyitiao,Haidian District,beijing 100190,China 3.{12. university of the Chinese academy of sciences,19 A Yuquan Road,beijing,100049,China.

＜正＞Hypogeomagnetic field（HGMF）refers to a geomagnetic field（GMF）eliminated environment,which is one of the characteristic environmental factor in outer space. Recent studies have shown that hypogeomagnetic exposures exhibit adverse effects on embryonic development and animal ***,astronauts are under potential risks due to the hypogeomagnetic aerospace during the space missions. However,the mechanisms of the HGMF effects remain unclear.

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2774-2790页

作者： Mingjing Yan Junpeng Gao Ming Lan Que wang Yuan Cao Yuxuan Zheng Yao Yang Wenlin Li Xiaoxue Yu Xiuqing Huang Lin Dou Bing Liu Junmeng Liu Hongqiang Cheng Kunfu Ouyang Kun Xu Shenghui Sun Jin Liu Weiqing Tang Xiyue zhang Yong Man Liang Sun {2.ping Cai Qing He Fuchou Tang {2. Li Tao Shen The Key Laboratory of Geriatrics Beijing Institute of GeriatricsInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing Hospital/National Center of Gerontology of National Health CommissionBeijing 100730China Peking university Fifth school of Clinical Medicine Beijing 100730China Department of Laboratory Medicine Huashan HospitalShanghai Medical CollegeFudan UniversityShanghai 200040China Biomedical Pioneering Innovation Center School of Life SciencesPeking UniversityBeijing 100871China Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Cardiology Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China graduate school of Peking Union Medical College Beijing 100730China Department of Health Care Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China Peking-Tsinghua Center for Life sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Department of Pathology and Pathophysiology and Department of Cardiology at Sir Run Run Shaw Hospital Zhejiang University School of MedicineHangzhou 310058China Department of Cardiovascular Surgery Peking University Shenzhen HospitalShenzhen 518036China Experimental technology Center for Life sciences at {2. Normal {3. Beijing 100875China

DEAD-box helicase 17(DDX17)is a typical member of the DEAD-box family with transcriptional cofactor *** DDX17 is abundantly expressed in the myocardium,its role in heart is not fully *** generated cardiomyocyte-specific Ddx17-knockout mice(Ddx17-cKO),cardiomyocyte-specific Ddx17 transgenic mice(Ddx17-Tg),and various models of cardiomyocyte injury and heart failure(HF).DDX17 is downregulated in the myocardium of mouse models of heart failure and cardiomyocyte ***-specific knockout of Ddx17 promotes autophagic flux blockage and cardiomyocyte apoptosis,leading to progressive cardiac dysfunction,maladaptive remodeling and progression to heart *** of DDX17 expression in cardiomyocytes protects cardiac function under pathological *** studies showed that DDX17 can bind to the transcriptional repressor B-cell lymphoma 6(BCL6)and inhibit the expression of dynamin-related protein 1(DRP1).When DDX17 expression is reduced,transcriptional repression of BCL6 is attenuated,leading to increased DRP1 expression and mitochondrial fission,which in turn leads to impaired mitochondrial homeostasis and heart *** also investigated the correlation of DDX17 expression with cardiac function and DRP1 expression in myocardial biopsy samples from patients with heart *** findings suggest that DDX17 protects cardiac function by promoting mitochondrial homeostasis through the BCL6-DRP1 pathway in heart failure.

关键词： DDX17 homeostasis cardiac

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喀斯特生态系统服务研究进展与展望

贵州师范大学学报（自然科学版） 2024年第5期42卷 77-84,105页

作者：王佳斌彭建张日玄徐子涵刘焱序北京大学深圳研究生院城市规划与设计学院广东深圳518055 北京大学城市与环境学院/自然资源部生态系统一体化修复与可持续利用工程技术创新中心北京100871 北京林业大学水土保持学院北京100083 北京师范大学地理科学学部地表过程与资源生态国家重点实验室北京100875

喀斯特生态系统脆弱,密集的人类活动导致了我国喀斯特地区生态系统的退化,影响了区域生态系统服务供给和人类福祉提升。论文概述了当前喀斯特生态系统服务领域的发文变化,并总结了三大热点研究方向:喀斯特生态系统服务估值及其时空变化... 详细信息

喀斯特生态系统脆弱,密集的人类活动导致了我国喀斯特地区生态系统的退化,影响了区域生态系统服务供给和人类福祉提升。论文概述了当前喀斯特生态系统服务领域的发文变化,并总结了三大热点研究方向:喀斯特生态系统服务估值及其时空变化;喀斯特生态系统服务社会-生态驱动因素;喀斯特生态系统服务权衡协同关系。同时,提出了四大未来重点研究方向,包括基于地质-社会-生态条件选取关键喀斯特生态系统服务,喀斯特生态系统服务垂向流动,喀斯特生态系统服务与人类福祉级联,以及生态工程对喀斯特生态系统服务的影响。

关键词：喀斯特生态系统服务垂向流人类福祉生态工程

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Optimizing thermoelectric properties of BiSe through Cu additive enhanced effective mass and phonon scattering

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Rare Metals 2020年第12期39卷 1374-1382页

作者： Xing-Chen Shen Xiao zhang Bin zhang Guo-Yu {2. {3. He Xiao-Yuan Zhou Chongqing Key Laboratory of Soft Condensed Matter Physics and Smart Materials College of PhysicsChongqing UniversityChongqing 401331China Chongqing Institute of Green and Intelligent technology Chinese Academy of ScienceChongqing 400714China Department of Physics and Astronomy Clemson UniversityClemsonSC29634USA Analytical and Testing Center of Chongqing university Chongqing401331China university of Chinese academy of {2. Beijing100044China

Known as a weak topological insulator(TI),BiSe structurally exhibits alternating stacks of quantum spin Hall bilayer("Bi_(2.")and three-dimensional TI layer("Bi_(2.Se_(3.").The low lattice thermal conductivity of BiSe due to the presence of Bi2.bilayers promises potentially good thermoelectric ***,the thermoelectric properties of nominal Bi_(1-x)Cu_(x)Se samples were studied as the functions of the content of Cu additive and *** is found that Cu additives in BiSe(1)profoundly affect the texture of densified polycrystalline samples by inclining the crystallographic c-axis parallel toward the pressure direction in the densification process,(2.increase considerably the effective mass and thus the Seebeck coefficient,and(3.yield point defects and Cu-Se secondary phases that effectively scatter heat-carrying *** a result,the optimized electrical and thermal properties yield a thermoelectric figure of merit of zT~0.2. in Bi_(1-x)Cu_(x)Se(x=0.03.sample at 467 K in parallel to the pressure direction and a zT~0.2. at 468 K in the perpendicular direction.

关键词： Cu additives Phonon scattering Effective mass Texture Thermoelectric

Cryo-electron microscopy structure of the intact photosynthetic light-harvesting antenna-reaction center complex from a green sulfur bacterium

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Journal of Integrative Plant Biology 2023年第1期65卷 223-234页

作者： Jing-Hua Chen Weiwei wang Chen wang Tingyun Kuang {2.-Ren Shen Xing {3. College of Life science Zhejiang {2. Hangzhou 310058 China Department of Pathology of Sir Run Run Shaw Hospital and Department of Biophysics Zhejiang University School of MedicineHangzhou 310058 China Key Laboratory of Photobiology Institute of BotanyPhotosynthesis Research Center the Chinese Academy of SciencesBeijing 100093 China Research Institute for Interdisciplinary science and Graduate School of Natural Science and Technology Okayama UniversityOkayama 700-8530 Japan Center of Cryo Electron Microscopy Zhejiang university {2. of Medicine Hangzhou 310058 China

The photosynthetic reaction center complex(RCC)of green sulfur bacteria(GSB)consists of the membrane-imbedded RC core and the peripheric energy transmitting proteins called Fenna–Matthews–Olson(FMO).Functionally,FMO transfers the absorbed energy from a huge peripheral light-harvesting antenna named chlorosome to the RC core where charge separation *** vivo,one RC was found to bind two FMOs,however,the intact structure of RCC as well as the energy transfer mechanism within RCC remain to be *** we report a structure of intact RCC which contains a RC core and two FMO trimers from a thermophilic green sulfur bacterium Chlorobaculum tepidum at 2.9A resolution by cryo-electron *** second FMO trimer is attached at the cytoplasmic side asymmetrically relative to the first FMO trimer reported *** also observed two new subunits(PscE and PscF)and the N-terminal transmembrane domain of a cytochrome-containing subunit(PscC)in the *** two novel subunits possibly function to facilitate the binding of FMOs to RC core and to stabilize the whole complex.A new bacteriochlorophyll(numbered as 816)was identified at the interspace between PscF and PscA-1,causing an asymmetrical energy transfer from the two FMO trimers to RC *** on the structure,we propose an energy transfer network within this photosynthetic apparatus.

关键词： cryo-electron microscopy energy transfer FMO protein green sulfur bacterium photosynthesis reaction center

Simulation of Hydrogen Emission Spectrum in Debye Plasmas

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Chinese Physics Letters 2011年第5期28卷 84-87页

作者： DING Qi-Yong zhang Song-Bin wang {2.-Guo The Key Laboratory of Computational Physics Institute of Applied Physics and Computational MathematicsP.O.Box 8009Beijing 100088 graduate school of China {2. of Engineering Physics P.O.Box 2101Beijing 100088 Hefei National Laboratory for Physical sciences at Microscale and Department of Modern Physics University of Science and Technology of ChinaHefei 230026

We investigate the screening effects on the spectrum of spontaneous radiation and radiative recombination to the 1s,2. and 2. states of hydrogen with total atom density N=1.7×10^(19)cm^(-3.and electron temperatures 1eV,2.V and 5eV under the local thermodynamic equilibrium(LTE)*** needed atomic energy levels,the radiative transition probabilities and radiative recombination cross sections are calculated by solving the Schr(o)dinger equation numerically incorporating the Debye-Hückel model in *** plasma emission spectrum is simulated for the first time by using the screened atomic *** red shift and the cutoff of Rydberg spectra are observed and it is also found that the 2.eV electron temperature case has the strongest screening effects and the emission spectra to the 2. and 2. states are more likely affected by screening effects than that of the ls state.

关键词： Debye radiative spectrum

Atorvastatin combined with low-dose dexamethasone for vascular endothelial cell dysfunction induced by chronic subdural hematoma

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Neural Regeneration Research 2021年第3期16卷 523-530页

作者： Yue-Shan Fan Bo wang Dong wang Xin Xu Chuang Gao Ying Li Shu {2. Gui-Li Yang Xiao Liu Rong-Cai {3.g {3.-Ning {2. Department of Neurosurgery General Hospital of Tianjin Medical UniversityTianjinChina Tianjin Neurological Institute Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous SystemMinistry of Education and Tianjin CityTianjinChina graduate school Tianjin Medical UniversityTianjinChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina

Atorvastatin has been shown to be a safe and effective non-surgical treatment option for patients with chronic subdural ***,treatment with atorvastatin is not effective in some patients,who must undergo further surgical *** has anti-inflammatory and immunomodulatory effects,and low dosages are safe and effective for the treatment of many diseases,such as ankylosing spondylitis and community-acquired ***,the effects of atorvastatin and low-dose dexamethasone for the treatment of chronic subdural hematoma remain poorly *** samples of patients with chronic subdural hematoma admitted to the General Hospital of Tianjin Medical university of China were collected and diluted in endothelial cell medium at 1:1 as the hematoma ***,dexamethasone,or their combination was added to the culture *** main results were as follows:hopping probe ion conductance microscopy and permeability detection revealed that the best dosages to improve endothelial cell permeability were 0.1μM atorvastatin and 0.1μM ***,dexamethasone,or their combination could markedly improve the recovery of injured endothelial *** subcutaneously injected with diluted hematoma solution and then treated with atorvastatin,dexamethasone,or their combination exhibited varying levels of rescue of endothelial cell *** probe ion conductance microscopy,western blot assay,and polymerase chain reaction to evaluate the status of human cerebral endothelial cell status and expression level of tight junction protein indicated that atorvastatin,dexamethasone,or their combination could reduce subcutaneous vascular leakage caused by hematoma ***,the curative effect of the combined treatment was significantly better than that of either single *** of Krüppel-like factor 2.protein in human cerebral endothelial cells was significantly increased,as was expression of the tight junctio

关键词： brain brain trauma cells central nervous system inflammation plasticity protein repair