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Enhanced thermoelectric and mechanical properties of Bi_(0.5)Sb_(1.5)Te_(3) alloy with dispersed yttrium oxide ceramic nanoparticles

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Rare Metals 2024年第4期43卷 1758-1768页

作者： Cun-Cheng Li ming-Wei zhang Ji-Wu Xin Lei Wei Wen-Yu Zhao School of Materials Science and Engineering Shandong University of TechnologyZibo255000China School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore639798Singapore State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan430070China

Reducing thermal conductivity while avoiding adverse interfacial reactions during sintering is crucial for improving the thermoelectric performance of Bi_(2)Te_(3)based *** ceramic nanoparticles are good candidates for achieving this *** this study,we designed and prepared a series of p-type Bi_(0.5)Sb_(1.5)Te_(3)nanocomposites decorated with Y_(2)O_(3)ceramic nanoparticles via ball-milling dispersion and spark-plasma *** to the chemical stability of the ceramics,no traces of atomic doping or interfacial reactions were *** measurements revealed that the Y_(2)O_(3)nanoparticles distributed along the grain boundaries acted as energy-dependent carrier-filtering centers to improve the scattering parameter and Seebeck coefficient,contributing to the elevated power factor even with a decreased electrical ***,the incorporated Y_(2)O_(3)nanoparticles and various defect structures they induced effectively strengthened the phonon scattering and suppressed the lattice thermal ***,a peak figure of merit(ZT)of 1.23 at 313 K was achieved for 0.4%Y_(2)O_(3)/Bi_(0.5)Sb_(1.5)Te_(3),which is 13%higher than that of the *** addition,the Vickers hardness of the composite material was 35%higher than that of the *** study demonstrates the effectiveness of ceramic nanoparticles in synergistic ally improving the thermoelectric and mechanical properties,which may be further extended to other thermoelectric systems.

关键词： Bi_(0.5)Sb_(1.5)Te_3 alloy Y_(2)O_(3) ceramic nanoparticles Microstructures Thermoelectric performance Mechanical properties

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Genetic Engineered Ultrasound-Triggered Injectable Hydrogels for Promoting Bone Reconstruction

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Research 2024年第2期2023卷 431-447页

作者： Zhenyu Zhao Huitong Ruan Aopan Chen Wei Xiong mingzhu zhang ming Cai Wenguo Cui Department of Orthopaedics Shanghai Tenth People's HospitalSchool of MedicineTongji University No.301 Middle Yanchang RoadShanghai 200072China Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University Schoolof Medicine197 Rujin 2nd RoadShanghai 200025China Department of Foot and Ankle Surgery Beijing Tongren HospitalCapital Medical University1 Dongjiao MinxiangBeijing 100730China

Genetic engineering technology can achieve specific gene therapy for a variety of diseases, but the current strategy still has some flaws, such as a complex system, single treatment, and large implantation trauma. Herein, the genetic engineering injectable hydrogels were constructed by ultrasonic technology for the first time to realize in vivo ultrasound-triggered in situ cross-linking and cell gene transfection, and finally complete in situ gene therapy to promote bone reconstruction. First, ultrasound-triggered calcium release was used to activate transglutaminase and catalyze the transamidation between fibrinogen. Simultaneously, liposome loaded with Zinc-finger E-box-binding homeobox 1 (ZEB1) gene plasmid (Lip-ZEB1) was combined to construct an ultrasound-triggered in situ cross-linked hydrogels that can deliver Lip-ZEB1. Second, ultrasound-triggered injectable hydrogel introduced ZEB1 gene plasmid into endothelial cell genome through Lip-ZEB1 sustained release, and then acted on the ZEB1/Notch signal pathway of cells, promoting angiogenesis and local bone reconstruction of osteoporosis through genetic engineering. Overall, this strategy provides an advanced gene delivery system through genetic engineered ultrasound-triggered injectable hydrogels.

关键词： sustained release linking

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美国国会“台湾连线”成员分布决定因素实证分析

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台湾研究集刊 2009年第3期 1-10页

作者：张光刁大明厦门大学公共事务学院南开大学周恩来政府管理学院

2002年成立的美国国会台湾连线已成为美国国会议员介入美国对华、对台政策的重要渠道。本文对台湾连线成员在第110届国会众议院的分布进行了实证研究,发现加入该连线的议员多来自美国南部,来自那些亚裔人口比重较大、与中国经济关系密切... 详细信息

2002年成立的美国国会台湾连线已成为美国国会议员介入美国对华、对台政策的重要渠道。本文对台湾连线成员在第110届国会众议院的分布进行了实证研究,发现加入该连线的议员多来自美国南部,来自那些亚裔人口比重较大、与中国经济关系密切、'“台独”'组织FAPA活跃的选区。外交委员会成员、意识形态保守议员和共和党议员参与台湾连线几率较高。基于台湾连线分布的特点,本文提出理性处理台湾问题中美国国会因素的建议。

关键词：美国国会台湾连线成员分布决定因素

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QAAS:quick accurate auto-scaling for streaming processing

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Frontiers of Computer Science 2024年第1期18卷 5-15页

作者： Shiyuan LIU Yunchun LI Hailong YANG ming DUN Chen CHEN Huaitao zhang Wei LI State Key Laboratory of Software Development Environment Beijing 100191China School of Computer Science and Engineering Beihang UniversityBeijing 100191China School of Cyber Science and Technology Beihang UniversityBeijing 100191China School of Computer Science and Technology Xi’an Jiaotong UniversityXi’an 710049China

In recent years,the demand for real-time data processing has been increasing,and various stream processing systems have *** the amount of data input to the stream processing system fluctuates,the computing resources required by the stream processing job will also *** resources used by stream processing jobs need to be adjusted according to load changes,avoiding the waste of computing *** present,existing works adjust stream processing jobs based on the assumption that there is a linear relationship between the operator parallelism and operator resource consumption(e.g.,throughput),which makes a significant deviation when the operator parallelism *** paper proposes a nonlinear model to represent operator *** divide the operator performance into three stages,the Non-competition stage,the Non-full competition stage,and the Full competition *** our proposed performance model,given the parallelism of the operator,we can accurately predict the CPU utilization and operator *** with actual experiments,the prediction error of our model is below 5%.We also propose a quick accurate auto-scaling(QAAS)method that uses the operator performance model to implement the auto-scaling of the operator parallelism of the Flink *** to previous work,QAAS is able to maintain stable job performance under load changes,minimizing the number of job adjustments and reducing data backlogs by 50%.

关键词： stream processing performance model auto-scaling

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Twisted Integration of Complex Oxide Magnetoelectric Heterostructures via Water‑Etching and Transfer Process

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Nano-Micro Letters 2024年第1期16卷 360-369页

作者： Guannan Yang Guohua Dong Butong zhang Xu Xu Yanan Zhao Zhongqiang Hu ming Liu State Key Laboratory for Manufacturing Systems Engineering Electronic Materials Research LaboratoryKey Laboratory of the Ministry of EducationEngineering Research Center of Spin Quantum Sensor ChipsUniversities of Shaanxi ProvinceSchool of Electronic Science and EngineeringXi’an Jiaotong UniversityXi’an 710049People’s Republic of China

Manipulating strain mode and degree that can be applied to epitaxial complex oxide thin films have been a cornerstone of strain *** recent years,lift-off and transfer technology of the epitaxial oxide thin films have been developed that enabled the integration of heterostructures without the limitation of material types and crystal ***,twisted integration would provide a more interesting strategy in artificial magnetoelectric heterostructures.A specific twist angle between the ferroelectric and ferromagnetic oxide layers corresponds to the distinct strain regulation modes in the magnetoelectric coupling process,which could provide some insight in to the physical *** this work,the La_(0.67)Sr_(0.33)MnO_(3)(001)/0.7Pb(Mg_(1/3)Nb_(2/3))O_(3)-0.3PbTiO_(3)(011)(LSMO/PMN-PT)heterostructures with *** *** angles were assembled via water-etching and transfer *** transferred LSMO films exhibit a fourfold magnetic anisotropy with easy axis along LSMO.A coexistence of uniaxial and fourfold magnetic anisotropy with LSMO[110]easy axis is observed for the 45°Sample by applying a 7.2 kV cm^(−1)electrical field,significantly different from a uniaxial anisotropy with LSMO[100]easy axis for the 0°*** fitting of the ferromagnetic resonance field reveals that the strain coupling generated by the 45°twist angle causes different lattice distortion of LSMO,thereby enhancing both the fourfold and uniaxial *** work confirms the twisting degrees of freedom for magnetoelectric coupling and opens opportunities for fabricating artificial magnetoelectric heterostructures.

关键词： Magnetoelectric heterostructures Twist angle Epitaxial lift-off Magnetic anisotropy Ferromagnetic resonance

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Combined Effect of Temperature and Cadmium on Molecular Responses of Hsp70 and P-gp Genes in Crassostrea gigas

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Journal of Ocean University of China 2024年第4期23卷 1115-1120页

作者： HU Fanguang SUN ming LIU Guangbin JING Yuanyuan CHEN Qun zhang Tianwen Marine Science Research Institute of Shandong Province Qingdao 266104China

To evaluate the combined effect of temperature and cadmium on the molecular responses of heat shock protein 70(hsp70)and P-glycoprotein(P-gp)in mantle,digestive gland and gills of Crassostrea gigas,oysters were exposed to combinations of five temperature levels(10,15,20,25,and 30℃)and 10μg L^(-1)cadmium for 21 *** were sampled for mRNA quantification by qPCR,and the results showed that the P-gp gene expression changed significantly after treatment at different temperatures and different treatment *** P-gp gene expression was the highest in the digestive *** with the control group,the P-gp gene expression in cadmium treatment groups at all the different temperatures were significantly higher than the control *** control oysters(kept at 10℃during the whole experiment without cadmium)expressed low levels of hsp70,but the groups treated with cadmium displayed somewhat higher *** present study demonstrated hsp70 and P-gp played an important role in the detoxification of Cd in ***,and confirmed temperature should be considered for the assessment of Cd-induced toxicity in oysters.

关键词： temperature cadmium P-gp hsp70 Crassostrea gigas

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鲁西北潘店重磁异常带矽卡岩型铁矿精细找矿方向——来自广域电磁法深部找矿的启示

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物探与化探 2024年第2期48卷 327-333页

作者：郭国强李亚东王阳于嘉宾王润生高晓丰张大明胡东宁方磊国玮芳山东省物化探勘查院山东济南250013 山东省地质勘查工程技术研究中心山东济南250013 地下资源环境高精度探测山东省工程研究中心山东济南250013 山东省第一地质矿产勘查院山东济南2501019 河北省煤田地质局物测地质队河北邢台054000

山东省鲁西北潘店地区超深覆盖区航磁和重力异常明显,通过系统的重磁异常查证工作,在研究区重磁异常带开展的多个钻孔均取得了深部矽卡岩型铁矿床找矿突破,但由于重磁异常带范围较大且其特征不能直接指示找矿方向,造成部分钻孔不见矿或... 详细信息

山东省鲁西北潘店地区超深覆盖区航磁和重力异常明显,通过系统的重磁异常查证工作,在研究区重磁异常带开展的多个钻孔均取得了深部矽卡岩型铁矿床找矿突破,但由于重磁异常带范围较大且其特征不能直接指示找矿方向,造成部分钻孔不见矿或见矿情况差。因此,为了更好地在重磁异常带精细圈定成矿位置,实现新的更大的找矿大突破,本文旨在已查证的潘店重磁异常带开展广域电磁测深(WFEM)工作,结合钻探验证情况,圈定深覆盖区矽卡岩型铁矿深部成矿区间及成矿有利结构面,提出深部精细找矿方向。

关键词：潘店地区矽卡岩型铁矿重磁异常带广域电磁测深精细找矿方向

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Electrochemical Reduction of Benzo[b]thiophene 1,1-Dioxides with HFIP as Hydrogen Donor

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Chinese Journal of Chemistry 2024年第6期42卷 585-591页

作者： ming-Zhong Guo Mei-Jin Mou Zhuo Chen Shao-Fei Ni ming Li Li-Rong Wen Lin-Bao zhang State Key Laboratory Base of Eco-Chemical Engineering College of Chemistry and Molecular EngineeringQingdao University of Science & TechnologyQingdaoShandong266042 China Department of Chemistry and Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province Shantou UniversityShantouGuangdong515063 China

A straightforward electrochemical reduction of benzo[b]thiophene 1,1-dioxides with HFIP as the hydrogen donor has been reported in an undivided cell under metal-free ***,the tolerance of various functional groups and ... 详细信息

关键词： Electrochemistry Reduction Benzo[b]thiophene 1,1-dioxides Deuterium Hydrogen source

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电动汽车用异步电机矢量控制系统仿真分析

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系统仿真学报 2007年第16期19卷 3761-3765页

作者：陈勇张大明姜丕杰辽宁工业大学汽车与交通工程学院辽宁锦州121001

根据异步电机矢量控制原理,建立了电动汽车用异步电机的仿真模型和转子磁场定向下的矢量控制系统模型,并在Matlab/Simulink软件环境下对其进行建模。考虑到时间的延迟,根据定子电压解耦修正算法推导了分析模型,仿真分析结果表明可以改... 详细信息

根据异步电机矢量控制原理,建立了电动汽车用异步电机的仿真模型和转子磁场定向下的矢量控制系统模型,并在Matlab/Simulink软件环境下对其进行建模。考虑到时间的延迟,根据定子电压解耦修正算法推导了分析模型,仿真分析结果表明可以改善高频控制的效果。以实际电动汽车用电机为例对模型进行仿真分析,该电机模型具有良好的稳态、动态性能,表明该仿真模型是实用的和有效的。

关键词：电动汽车异步电机矢量控制动态仿真

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Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy

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Journal of Pharmaceutical Analysis 2024年第3期14卷 401-415页

作者： Ke-Gang Linghu Tian zhang Guang-Tao zhang Peng Lv Wen-Jun zhang Guan-Ding Zhao Shi-Hang Xiong Qiu-Shuo Ma ming-ming Zhao Meiwan Chen Yuan-Jia Hu Chang-Sheng zhang Hua Yu State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SARChina Macao Centre for Research and Development in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SARChina Key Laboratory of Tropical Marine Bio-resources and Ecology Guangdong Key Laboratory of Marine Materia MedicaRNAM Center for Marine MicrobiologySouth China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou510301China State Key Laboratory of Functions and Applications of Medicinal Plants&School of Pharmaceutical Sciences Guizhou Medical UniversityGuiyang550025China

Activation of nuclear factor erythroid 2-related factor 2(Nrf2)by Kelch-like ECH-associated protein 1(Keap1)alkylation plays a central role in anti-inflammatory ***,activators of Nrf2 through alkylation of Keap1-Kelch domain have not been ***(DNQ)is a natural small molecule discovered from marine *** current study was designed to investigate the anti-inflammatory effects and molecular mechanisms of DNQ via alkylation of *** exhibited significant anti-inflammatory properties both in vitro and in *** pharmacophore responsible for the anti-inflammatory properties of DNQ was determined to be theα,β-unsaturated amides moieties by a chemical reaction between DNQ and *** exerted anti-inflammatory effects through activation of Nrf2/ARE ***1 was demonstrated to be the direct target of DNQ and bound with DNQ through conjugate addition reaction involving *** specific alkylation site of DNQ on Keap1 for Nrf2 activation was elucidated with a synthesized probe in conjunction with liquid chromatography-tandem mass *** triggered the ubiquitination and subsequent degradation of Keap1 by alkylation of the cysteine residue 489(Cys489)on Keap1-Kelch domain,ultimately enabling the activation of *** findings revealed that DNQ exhibited potent anti-inflammatory capacity throughα,β-unsaturated amides moieties active group which specifically activated Nrf2 signal pathway via alkylation/ubiquitination of Keap1-Kelch domain,suggesting the potential values of targeting Cys489 on Keap1-Kelch domain by DNQ-like small molecules in inflammatory therapies.

关键词： Deoxynyboquinone Anti-inflammation Target Keap1/Nrf2 Alkylation Ubiquitination

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