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Solid liquid Mixed Casting of Al-Si Alloy

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Journal of Central South University 2000年第3期12卷 133-135页

作者： chen, zh Kang, ZT Cent S Univ Technol Dept Mat Sci & Engn Changsha 410083 Peoples R China

The paper presents a novel material preparation technology—Solid liquid mixed casting technology. In the technology, large amounts of homogeneous alloy powder or heterogenous powder with perfect wettability are added into the superheated melt. After strong agitation, the mixed melt can be cast or hot processed. Applying solid liquid mixed casting, three kinds of Al Si alloys were investigated. The results show that, when the mass of powder accession to alloy melt is about 1, the mean size of primary Si in hyper eutectic alloy can be controlled at less than 5 μm; and the mean grain size of α phase in hypo eutectic alloy is less than 10 μm. This technology has the advantage of preparing material with very fine microstructure by fairly simple casting process, and may be a new practicable and valuable metal preparation technology.

关键词： solid liquid mixed casting powder melt Document code:A

Room-temperature deposition of yttria-stabilized zirconia buffer layer on metallic substrates by laser ablation

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Chinese Science Bulletin 1997年第16期42卷 1345-1350页

作者： Xiong, XM zhou, YL chen, zh Lu, HB zhu, AJ Cui, DF Wang, HS Yang, GZ Chinese Acad Sci Inst Phys Lab Opt Phys Beijing 100080 Peoples R China Chinese Acad Sci Ctr Condensed Matter Phys Beijing 100080 Peoples R China

THE preparation of high-temperature superconducting (HTSC) wires or tapes is very important for the power application of HTSC. High-J_c properties of Y-Ba-Cu-O thin film at liq uid-nitrogen temperature are very attractive not only for small-sized electronic devices, but also for large-scale applications such as high-power transmission cables, high-field magnets and large-scale microwave components. Large-current power application would be achieved if high-J_c YBCO films were grown on practical cheap and flexible metallic substrates. An yttria-stabi-

关键词： YSZ low temperature PLD buffer layer metal substrate.

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中国有色金属学会会刊：英文版 2001年第6期11卷 843-846页

作者： Yan, HG chen, zh Kang, ZT chen, G Hunag, PY Hunan Univ Sch Mat Sci & Engn Changsha 410082 Peoples R China Cent S Univ Dept Mat Sci & Engn Changsha 410083 Peoples R China

The phase formation regularities in nanometer powders of ternary alloys prepared by gas evaporation process with induction current as the heating source were investigated. Al-Cu-Mn and Al-Cu-Cr were chosen as the samples in this study. The experimental results show that the necessary conditions for forming ternary compound phases in a ternary alloy nanometer powder are that they must be able to form in a conventional bulk alloy. To obtain a ternary compound phase in nanometer powders, composition of the master alloy must be in a certain range. Changing the composition of the master alloy and evaporation temperature can control the kinds of the phases and their relative amount in the alloy nanometer powders. In present study, AlMn, Al8Mn5 and AlCu2Mn phases formed in as-prepared nanometer powders of Al-Cu-Mn alloy, and the highest relative amount of AlCu2Mn phase is about 99%. In nanometer powders of Al-Cu-Cr alloy,Cu9Al4, Al2Cu3, AlCr2 and Al13Cr2 phases formed without any ternary compound phase.

关键词： nanometer powder gas evaporation alloy powder

Effects of epitopes combination and adjuvants on immune responses to anti-Alzheimer disease DNA vaccines in mice

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第二军医大学学报 2006年第5期27卷 589-589页

作者： He Y Sun SH chen RW Guo YJ He XW Huang L chen zh Shi K zhu WJ Department of Medical Genetics College of Basic Medical Sciences Second Military Medical University Shanghai 200433 China

Alzheimer disease (AD) is a neurodegenerative disorder characterized by neuropathological hallmarks including deposits of theβ-amyloid peptide (AssP). Studies have shown that immunization with Aβ42 peptide reduces both the spatial memory impairments and Alzheimer disease-like neuropathologic changes in Alzheimer disease transgenic mice, but can cause side effect of a cell-mediated autoimmune meningoencephalitis. Recently, some studies showed that DNA vaccination could be used to generate an antibody response to Aβwithout the adverse cell-mediated immune effect. In the current study, we generate four DNA vaccine plasmids (pV-GE1, pV-GE2, pV-GE3, and pV-GE4) against Alzheimer disease by separately fusing Aβepitope sequences (coding for EFGH, DAEFGH, EFGH+EFGH, and EFGH+DAEFGH) with IgG heavy chain coding region of mouse. Meanwhile, the full-length gene Aβencoding plasmid (pV-Aβ), empty vector (pVAX) and synthetic AssP were also included as control. The sera of BALB/c mice immunized via intramuscular with plasmids and peptide were tested by indirect

关键词：老年痴呆抗原免疫反应 DNA疫苗

DNA vaccination using bacillus Calmette-Guerin-DNA as an adjuvant to enhance immune response to three kinds of swine diseases

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第二军医大学学报 2006年第6期27卷 606-606页

作者： zhang S Guo YJ Sun SH Wang KY Wang KH zhang Y zhu WJ chen zh Jiang L Department of Medical Genetics College of Basic Medical SciencesSecond Military Medical University Shanghai 200433 China

In order to enhance the immune efficacy of DNA vaccination, experiments were conducted to investigate the regulating effects of Bacillus Calmette-Guerin (BCG)-DNA as an adjuvant on immune responses of mice against foot-and-mouth disease (FMD), Aujeszky's disease (AID) and classical swine fever (CSF)。BCG-DNA was purified from BCG by ion-exchange chromatography。Three DNA vaccines (pVSG, pVgD and pVE2) against the respective infection were constructed, and BCGDNA was coimmunized to mice by muscle injection。The results showed that titres of specific immunoglobulin (Ig)G to the vaccines mounted remarkably in the sera of the adjuvant covaccinated mice (P 0.05)。These results suggest that codelivery of BCG-DNA with DNA vaccines against FMD, AjD and CSF can enhance the induction of antigen-specific, especially, cell-mediated immunity。

关键词： DNA疫苗免疫反应疾病预防

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质量比对刚性圆柱体涡激振动影响的研究

振动与冲击 2017年第11期36卷 248-254页

作者：陈正寿赵宗文张国辉郑武颜盛汉浙江海洋大学船舶与机电工程学院浙江舟山316022 浙江省近海海洋工程技术重点实验室浙江舟山316022 太平洋海洋工程(舟山)有限公司浙江舟山316057 浙江欧华造船股份有限公司浙江舟山316101

基于CFD方法,开展了质量比对刚性圆柱体涡激振动影响的研究。对低质量比分别为1和2.4和高质量比为7的刚性圆柱体分别进行双自由度涡激振动流固耦合模拟,得到了不同质量比工况下无因次振幅与约化速度之间的相关性,圆柱体的"8"字形运动轨... 详细信息

基于CFD方法,开展了质量比对刚性圆柱体涡激振动影响的研究。对低质量比分别为1和2.4和高质量比为7的刚性圆柱体分别进行双自由度涡激振动流固耦合模拟,得到了不同质量比工况下无因次振幅与约化速度之间的相关性,圆柱体的"8"字形运动轨迹以及"差拍"、"相位转换"等现象;初步的研究结果表明,低质量比的模型对应的振动锁振区范围要广于高质量比的模型,产生的横流向最大无因次振幅也较大,涡激振动现象更为显著。另外通过不同质量比对顺、横流向耦合振动影响的分析发现,在质量比为1和2.4时,顺流向振动对横流向振动产生的影响不容忽略,而在质量比为7时,其影响较小。另在涡激振动尾流区,捕捉到了"2S"、"2P"型泻涡发放。

关键词：质量比涡激振动流固耦合刚性圆柱体

Circulating HER2 extracellular domain(ECD) predicts a poor prognosis for metastatic breast cancer patients

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Circulating HER2 extracellular domain(ECD) predicts a poor p...

国家级“乳腺癌诊治新进展”学习班暨学术年会

作者： Shao XY Xu XH Wang S Huang J Cai JF Cao WM chen zh Huang P Lou CJ Ling ZQ Han MX Wang XJ zhejiang Cancer Research Institute Zhejiang Cancer Hospital

Background:Amplification or overexpression of HER2 has been shown to play an important role in approximately 30%of breast cancers and is strongly associated with increased recurrence and a worse *** HER2 extracellular domain(ECD) may be cleaved and shed from the surface of breast cancer cells and serum HER2 ECD levels can be detected by enzyme-linked immunosorbent assay (ELISA).In this study,we explored the relationship between circulating HER2 ECD and tissue HER2

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口蹄疫疫苗的正确使用

中国兽药杂志 2009年第9期43卷 55-56页

作者：陈征郑明中国兽医药品监察所北京100081

口蹄疫是发生在偶蹄动物中的一种急性、烈性、高度接触性传染病,发病率高,可引起大范围的易感动物感染发病,造成严重的经济损失.世界动物卫生组织(OIE)将之列为A类疫病中第一位烈性传染病,我国农业部也将其列为A类传染病之首.疫苗接种... 详细信息

口蹄疫是发生在偶蹄动物中的一种急性、烈性、高度接触性传染病,发病率高,可引起大范围的易感动物感染发病,造成严重的经济损失.世界动物卫生组织(OIE)将之列为A类疫病中第一位烈性传染病,我国农业部也将其列为A类传染病之首.疫苗接种是特异性预防该病的有效手段,如何选择安全有效的口蹄疫疫苗并正确使用,是预防和控制口蹄疫的关键因素之一.

关键词：口蹄疫疫苗世界动物卫生组织接触性传染病烈性传染病偶蹄动物动物感染经济损失疫苗接种

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抗寄生虫药物的正确使用

中国兽药杂志 2009年第12期43卷 53-55页

作者：陈征郑明中国兽医药品监察所北京100081

动物寄生虫病给养殖业造成很大的损失,抗寄生虫药物能消灭动物体内的寄生虫,治愈或减轻病情,促进畜体健康.合理地使用抗寄生虫药物,规范地治疗各种寄生虫病,在取得最佳疗效的同时,最大限度地避免不良反应的发生,还能有效消灭传染源,切... 详细信息

动物寄生虫病给养殖业造成很大的损失,抗寄生虫药物能消灭动物体内的寄生虫,治愈或减轻病情,促进畜体健康.合理地使用抗寄生虫药物,规范地治疗各种寄生虫病,在取得最佳疗效的同时,最大限度地避免不良反应的发生,还能有效消灭传染源,切断传播途径,预防寄生虫的感染.因此,正确使用抗寄生虫药非常重要.

关键词：抗寄生虫药物寄生虫病动物体内不良反应传播途径养殖业传染源畜