检索结果-南通市图书馆

Macro to nanoscale deformation of transformation-induced plasticity steels：Impact of aluminum on the microstructure and deformation behavior

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2018年第5期34卷 745-755页

作者： V.S.Y.Injeti z.c.li B.Yu R.D.K.Misra z.H.cai H.Ding Department of Metallurgical Materials and Biomedical Engineering500 W. University Avenue USA School of Materials Science and Engineering Northeastern University Shenyang 110819 China

This work aims to elucidate the impact of aluminum-content on microstructure and deformation mechanisms of transformation-induced plasticity（TRIP） steels through macroscale and nanoscale deformation experiments combined with post-mortem electron microscopy of the deformed *** solid-state transformation-induced mechanical deformation varied with the Al contents,and influenced tensile strength-ductility *** with 2–4 wt% Al were characterized by TRIP *** contrast to 2 Al-TRIP and 4 Al-TRIP steels,twinning-induced plasticity（TWIP） was also observed in conjunction with strain-induced martensite in 6 Al-TRIP *** behavior is attributed to the increase in stacking fault energy with the increase of Al content and stability of austenite,which depends on the local chemical *** study addresses the knowledge gap with regard to the effect of Al content on austenite stability in medium-Mn TRIP *** combination is expected to potentially enable cost-effective alloy design with high strength-high ductility condition.

关键词： Medium-manganese steels Aluminum content Electron microscopy Mechanical properties Nanoscale deformation TRIP steel Twinning

competition among the two-plasmon decay of backscattered light,filamentation of the electron-plasma wave and side stimulated Raman scattering

在线全文

学校读者我要写书评

暂无评论

High Power Laser Science and Engineering 2023年第6期11卷 87-94页

作者： K.Q.Pan z.c.li L.Guo T.Gong S.W.li D.Yang c.Y.zheng B.H.zhang X.T.He Laser Fusion Research center China Academy of Engineering PhysicsMianyangChina center for Applied Physics and Technology Peking UniversityBeijingChina Institute of Applied Physics and computational Mathematics BeijingChina

competition among the two-plasmon decay(TPD)of backscattered light of stimulated Raman scattering(SRS),filamentation of the electron-plasma wave(EPW)and forward side SRS is investigated by two-dimensional particlein-cell *** previous work[*** et al.,*** 58,096035(2018)]showed that in a plasma with the density near 1/10 of the critical density,the backscattered light would excite the TPD,which results in suppression of the backward ***,this work further shows that when the laser intensity is so high(>10^(16)W/cm^(2))that the backward SRS cannot be totally suppressed,filamentation of the EPW and forward side SRS will be *** the TPD of the backscattered light only occurs in the early stage and is suppressed in the latter *** distribution functions further show that trapped-particle-modulation instability should be responsible for filamentation of the *** research can promote the understanding of hot-electron generation and SRS saturation in inertial confinement fusion experiments.

关键词： laser plasma instability inertial confinement fusion high energy density physics particle-in-cell simulation super-hot electrons

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2019年第5期 626-627页

作者： z.c.li G.T.zhai J.H.zhang z.Q.Wang G.Q.liu G.Y.Wu 彭攀 Institute of Biomedical and Health Engineering Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences

摘要目的采用多期相增强cT全相关影像学特征建立影像组学模型以鉴别肾透明细胞癌(ccRcc)与非透明细胞癌,探索影像学特征与ccRcc关键致病基因VHL突变之间

关键词：肾透明细胞癌 VHL cT 影像组学基因突变

RNA modifications in the progression of liver diseases:from fatty liver to cancer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science china(life Sciences) 2024年第10期67卷 2105-2119页

作者： Simiao li Wajahat z Mehal Xinshou Ouyang Department of Internal Medicine Section of Digestive DiseasesYale University School of MedicineNew Haven CT 06520USA

Non-alcoholic fatty liver disease(NAFLD)has emerged as a prominent global health concern associated with high risk of metabolic syndrome,and has impacted a substantial segment of the *** disease spectrum ranges from simple fatty liver to non-alcoholic steatohepatitis(NASH),which can progress to cirrhosis and hepatocellular carcinoma(Hcc)and is increasingly becoming a prevalent indication for liver *** existing therapeutic options for NAFLD,NASH,and Hcc are limited,underscoring the urgent need for innovative treatment *** into gene expression,particularly RNA modifications such as N6methyladenosine(m^(6)A),hold promising avenues for *** modifications play integral roles in RNA metabolism and cellular functions,encompassing the entire NAFLD-NASH-Hcc *** review will encompass recent insights on diverse RNA modifications,including m^(6)A,pseudouridine(Ψ),N^(1)-methyladenosine(m^(1)A),and 5-methylcytidine(m^(5)c)across various RNA *** will uncover their significance in crucial aspects such as steatosis,inflammation,fibrosis,and ***,prospective research directions and therapeutic implications will be explored,advancing our comprehensive understanding of the intricate interconnected nature of these pathological conditions.

关键词： m^(6)A RNA modification NASH NAFLD Hcc fatty liver

Anisotropic time-dependent behaviors of shale under direct shearing and associated empirical creep models

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第4期16卷 1262-1279页

作者： Yachen Xie Michael z.Hou Hejuan liu cunbao li Shenzhen Key Laboratory of Deep Engineering Sciences and Green Energy Shenzhen UniversityShenzhen518060China Institute of Subsurface Energy Systems Clausthal University of TechnologyClausthal-Zellerfeld38678Germany State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China

Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging *** this context,we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.0°,30°,45°,60°,and 90°),under multiple levels of direct shearing for the first *** results show that the anisotropic creep of shale exhibits a significant stress-dependent *** a low shear stress,the creep compliance of shale increases linearly with the logarithm of time at all bedding orientations,and the increase depends on the bedding orientation and creep *** high shear stress conditions,the creep compliance of shale is minimal when the bedding orientation is 0°,and the steady-creep rate of shale increases significantly with increasing bedding orientations of 30°,45°,60°,and 90°.The stress-strain values corresponding to the inception of the accelerated creep stage show an increasing and then decreasing trend with the bedding orientation.A semilogarithmic model that could reflect the stress dependence of the steady-creep rate while considering the hardening and damage process is *** model minimizes the deviation of the calculated steady-state creep rate from the observed value and reveals the behavior of the bedding orientation's influence on the steady-creep *** applicability of the five classical empirical creep models is quantitatively *** shows that the logarithmic model can well explain the experimental creep strain and creep rate,and it can accurately predict long-term shear creep *** on an improved logarithmic model,the variations in creep parameters with shear stress and bedding orientations are *** abovementioned findings,a mathematical method for constructing an anisotropic shear creep model of shale is proposed,which can characterize the nonlinear dependence of the anisotropic shear creep behavior of shale on the bedding orientation.

关键词： Rock anisotropy Direct shear creep creep compliance Steady-creep rate Empirical model creep constitutive model

Enhancement of the surface emission at the fundamental frequency and the transmitted high-order harmonics by pre-structured targets

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High Power Laser Science and Engineering 2019年第2期7卷 111-119页

作者： K.Q.Pan D.Yang L.Guo z.c.li S.W.li c.Y.zheng S.E.Jiang B.H.zhang X.T.He Laser Fusion Research center China Academy cf Engineering PhysicsMianyang 621900.China center for Applied Physics and Technology Peking UniversityBeijing 100871China Institute of Applied Physics and computational Mathematics Beijing 100088China

Laser interaction with an ultra-thin pre-structured target is investigated with the help of both two-dimensional and threedimensional particle-in-cell *** the existence of aperiodic structure on the target surface,the laser seems to penetrate through the target at its fundamental frequency even if the plasma density of the target is much higher than the laser’s relativistically critical *** particle-in-cell simulations show that the transmitted laser energy behind the pre-structured target is increased by about two orders of magnitude compared to that behind the flat *** analyses show that the transmitted energy behind the pre-structured target is actually re-emitted by electron’islands’ formed by the surface plasma waves on the target *** other words,the radiation with the fundamental frequency is actually’surface emission,on the target rear *** the intensity of the component with the fundamental frequency,the intensity of the high-order harmonics behind the pre-structured target is also much enhanced compared to that behind the flat *** enhancement of the high-order harmonics is also related to the surface plasma waves generated on the target surfaces.

关键词： high-order harmonics generation high power laser laser-plasma interaction particle-in-cell simulation

Stability Investigation and Improvement for Dc cascade Systems with Simplified Impedance-based Stability criterion

在线全文

学校读者我要写书评

暂无评论

cSEE Journal of Power and Energy Systems 2024年第3期10卷 1044-1052页

作者： Junbin Fang zhikang Shuai Yang li zhibing Wang Xiangyang Wu Xia Shen z.John Shen college of Electrical and Information Engineering Hunan UniversityChangsha 410082China Renewable Energy Department of china Electric Power Research Institute Beijing 100192China Department of Electrical and computer Engineering Illinois Institute of TechnologyChicagoIL 60616USA IEEE

In Dc distributed power systems(DPSs),the complex impedance interactions possibly lead to Dc bus voltage oscillation or *** previous research,the stability analysis of DPSs is implemented based on mathematical analysis in control *** specific mechanisms of the instability of the cascade system have not been intuitively *** this paper,the stability analysis of DPSs based on the traditional Nyquist criterion is simplified to the resonance analysis of the seriesconnected port impedance(z=R+jX)of source and load *** reveals that the essential reason for impedance instability of a Dc cascade system is that the negative damping characteristic(Rce amplifies the internal resonance source at reactance zero-crossing *** simplified stability criterion for Dc cascade systems can be concluded as:in the negative damping frequency ranges(Rzero-crossing point of the reactance component(i.e.,X=0).According to the proposed stability criterion,the oscillation modes of cascade systems are classified.A typical one is the internal impedance instability excited by the negative damping,and the other one is that the external disturbance amplified by negativity in a low stability ***,the impedance reshaping method for stability improvement of the system can be further *** validity of the simplified criterion is verified theoretically and experimentally by a positive damping reshaping method.

关键词： Dc cascaded system,impedance model impedance reconstruction stability criterion

Targeting epigenetic mechanisms in amyloid-β-mediated Alzheimer’s pathophysiology:unveiling therapeutic potential

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 54-66页

作者： Jennie z.li Nagendran Ramalingam Shaomin li Ann Romney center for Neurologic Diseases Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

Alzheimer’s disease is a prominent chronic neurodegenerative condition characterized by a gradual decline in memory leading to *** evidence suggests that Alzheimer’s disease is associated with accumulating various amyloid-βoligomers in the brain,influenced by complex genetic and environmental *** memory and cognitive deficits observed during the prodromal and mild cognitive impairment phases of Alzheimer’s disease are believed to primarily result from synaptic *** life,environmental factors can lead to enduring changes in gene expression and the emergence of brain *** changes,known as epigenetic modifications,also play a crucial role in regulating the formation of synapses and their adaptability in response to neuronal *** this context,we highlight recent advances in understanding the roles played by key components of the epigenetic machinery,specifically DNA methylation,histone modification,and microRNAs,in the development of Alzheimer’s disease,synaptic function,and activity-dependent synaptic ***,we explore various strategies,including enriched environments,exposure to non-invasive brain stimulation,and the use of pharmacological agents,aimed at improving synaptic function and enhancing long-term potentiation,a process integral to epigenetic ***,we deliberate on the development of effective epigenetic agents and safe therapeutic approaches for managing Alzheimer’s *** suggest that addressing Alzheimer’s disease may require distinct tailored epigenetic drugs targeting different disease stages or pathways rather than relying on a single drug.

关键词： Alzheimer’s disease DNA methylation enriched environments histone modification microRNAs non-invasive brain stimulation synaptic plasticity

Effect of Al_(2)O_(3)on the Mechanical Properties of(B_(4)c+Al_(2)O_(3))/Al Neutron Absorbing Materials

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2024年第8期37卷 1411-1420页

作者： J.X.cai B.M.Shi N.li Y.liu z.G.zhang Y.N.zan Q.z.Wang B.L.Xiao z.Y.Ma Shi‑changxu Innovation center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Nuclear Equipment Division Beijing Institute of Nuclear EngineeringChina Nuclear Power Engineering Co.Ltd.Beijing 100840China Department of Materials Science School of Mechanical EngineeringShenyang UniversityShenyang 110044China

B_(4)c/Al composites are widely utilized as neutron absorbing materials for the storage and transportation of spent nuclear *** order to improve the high-temperature mechanical properties of B_(4)c/Al composites,in-situ nano-Al_(2)O_(3)was introduced utilizing oxide on Al powder *** this study,the Al_(2)O_(3)content was adjusted by utilizing spheroid Al powder with varying diameters,thereby investigating the impact of Al_(2)O_(3)content on the tensile properties of(B_(4)c+Al_(2)O_(3))/Al *** was found that the pinning effect of Al_(2)O_(3)on the grain boundaries could hinder the recovery of dislocations and lead to dislocation accumulation at high *** the result,with the increase in Al_(2)O_(3)content and the decrease in grain size,the high-temperature strength of the composites increased *** finest Al powder used in this investigation had a diameter of 1.4μm,whereas the resultant composite exhibited a maximum strength of 251 MPa at room temperature and 133 MPa at 350℃,surpassing that of traditional B_(4)c/Al composites.

关键词： Al matrix composites Neutron absorbing materials (B_(4)c+Al_(2)O_(3))/Al composites High-temperature strength