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In vivo and in vitro study of resorbable magnesium wires for medical implants:mg purity,surface quality,zn alloying and polymer coating

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Journal of magnesium and Alloys 2024年第6期12卷 2472-2488页

作者： K.Tesar J.Luňácková m.Jex m.Žaloudková R.Vrbová m.Bartoš P.Klein L.Vištejnová J.Dušková E.Filová z.sucha.da.m.steinerová S.Habr K.Balík A.Singh Department of materials Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueTrojanova 13Prague 12000Czech Republic Institute of Physics Czech Academy of SciencesNa Slovance 2Prague 18221Czech Republic Institute of Dental medicine First Faculty of MedicineCharles University and General University Hospital in PragueKaterinská32Prague 12801Czech Republic Department of Physics Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueBrehová7Prague 11519Czech Republic Department of Composites and Carbon materials Institute of Rock Structure and MechanicsCzech Academy of SciencesV Holešovickách 41Prague 18209Czech Republic Institute of Anatomy First Faculty of MedicineCharles UniversityU Nemocnice 3Prague 12800Czech Republic Biomedical Center Faculty of Medicine in PilsenCharles UniversityAlej Svobody 76Pilsen 32300Czech Republic Department of Pathological Physiology Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Department of Histology and Embryology Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Institute of Pathology First Faculty of MedicineCharles University and General University Hospital in PragueStudnickova 2Prague 12800Czech Republic Department of Biomaterials and Tissue Engineering Institute of PhysiologyCzech Academy of SciencesVidenska 1083Prague 14200Czech Republic Research Center for Structural materials National Institute for Materials Science1-2-1 SengenTsukuba 305-0047Japan

magnesium is an excellent material in terms of biocompatibility and its corrosion products can serve as an active source for new bone ***,localized corrosion and H_(2)generation limit the potential of mg-based *** low-alloyed mg-zn wires can strongly reduce problems with large H_(2)bubbles and improve the mechanical properties considerably while maintaining excellent long-term *** pickling and a polymer coating can be effectively used to lower the rate of in vivo *** this work,microstructural,mechanical,and in vitro characterization of 250μm and 300μm extruded wires made from ultra-pure mg,commercially pure mg,mg-0.15zn,mg-0.4zn and mg-1zn was ***,mg-0.4zn wires together with a variant coated with a copolymer of L-lactide andε-caprolactone were tested in vivo on artificially damaged Wistar rat *** on the observed mg-induced osteogenesis,polymer-coated mg wires with a small addition of zn are a perspective material for bone-support applications,such as cerclage and fixation wires.

关键词： magnesium Resorbable mg wire mg-zn implant degradation Biocompatibility study zn grain boundary segregation

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Effects of multiple shapes for steady flow with transformer oil+Fe_(3)O_(4)+TiO_(2) between two stretchable rotating disks

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Applied mathematics and mechanics(English Edition) 2024年第2期45卷 373-388页

作者： m.RAHmAN m.TURKYILmAzOGLU z.mUSHTAQ Department of mathematics Mirpur University of Science and TechnologyMirpur 10250Pakistan Department of mathematics Hacettepe UniversityBeytepeAnkara 06532Turkiye

In this study,we examine the effects of various shapes of nanoparticles in a steady flow of hybrid nanofluids between two stretchable rotating *** steady flow of hybrid nanofluids with transformer oil as the base fluid and Fe_(3)O_(4)+TiO_(2)as the hybrid nanofluid is *** shapes of Fe_(3)O_(4)+TiO_(2)hybrid nanofluids,including sphere,brick,blade,cylinder,and platelet,are *** shape exists in the same volume of a *** leading equations(partial differential equations(PDEs))are transformed to the nonlinear ordinary differential equations(ODEs)with the help of similarity *** system of equations takes the form of ODEs depending on the boundary conditions,whose solutions are computed numerically by the bvp4c mATLAB *** outputs are compared with the previous findings,and an intriguing pattern is discovered,such that the tangential velocity is increased for the rotation parameter,while it is decreased by the stretching values because of the lower *** the reaction rate parameter,the concentration boundary layer becomes shorter,and the activation energy component increases the rate at which mass transfers come to the higher disk but have the opposite effect on the bottom *** ranges of various parameters taken into account are Pr=6.2,Re=2,m=1.0,φ_(1)=φ_(2)=0.03,K=0.5,S=-0.1,Br=0.3,Sc=2.0,α_(1)=0.2,γ=0.1,E_(n)=2.0,and q=1.0,and the rotation factor K is within the range of 0 to 1.

关键词： transformer oil Brinkman number skin friction coefficient double rotating disk Nusselt number Sherwood number

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Fire resistance evaluation through synthetic fire tests and generative adversarial networks

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Frontiers of Structural and Civil Engineering 2024年第4期18卷 587-614页

作者： AybikeÖzyükselÇiftçioğlua m.z.Naser Department of Civil Engineering Manisa Celal Bayar University45140Türkiye School of Civil&Environmental Engineering and Earth Sciences(SCEEES) Clemson UniversityClemsonSC 29631USA Artificial Intelligence Research Institute for Science and Engineering(AIRISE) Clemson UniversityClemsonSC 29631USA

This paper introduces a machine learning approach to address the challenge of limited data resulting from costly and time-consuming fire experiments by enlarging small fire test data sets and predicting the fire resistance of reinforced concrete *** approach begins by creating deep learning models,namely generative adversarial networks and variational autoencoders,to learn the spatial distribution of real fire *** then use these models to generate synthetic tabular samples that closely resemble realistic fire resistance values for reinforced concrete *** generated data are employed to train state-of-the-art machine learning techniques,including Extreme Gradient Boost,Light Gradient Boosting machine,Categorical Boosting Algorithm,Support Vector Regression,Random Forest,Decision Tree,multiple Linear Regression,Polynomial Regression,Support Vector machine,Kernel Support Vector machine,Naive Bayes,and K-Nearest Neighbors,which can predict the fire resistance of the columns through regression and *** learning analyses achieved highly accurate predictions of fire resistance values,outperforming traditional models that relied solely on limited experimental *** study highlights the potential for using machine learning and deep learning analyses to revolutionize the field of structural engineering by improving the accuracy and efficiency of fire resistance evaluations while reducing the reliance on costly and time-consuming experiments.

关键词： deep learning fire resistance generative adversarial networks machine learning

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Dysregulation of RNA modification systems in clinical populations with neurocognitive disorders

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Neural Regeneration Research 2024年第6期19卷 1256-1261页

作者： Helen m.Knight merve Demirbugen ?z Adriana PerezGrovas-Saltijeral Division of Cells Organisms and Molecular Genetics School of Life Sciences University of Notingham Department of Pharmaceutical Toxicology Faculty of Pharmacy Ankara University

The study of modified RNA known as epitranscriptomics has become increasingly relevant in our understanding of disease-modifying mechanisms. methylation of N6 adenosine(m6A) and C5 cytosine(m5C) bases occur on mRNAs, tRNA, mt-tRNA, and rRNA species as well as non-coding RNAs. With emerging knowledge of RNA binding proteins that act as writer, reader, and eraser effector proteins, comes a new understanding of physiological processes controlled by these systems. Such processes when spatiotemporally disrupted within cellular nanodomains in highly specialized tissues such as the brain, give rise to different forms of disease. In this review, we discuss accumulating evidence that changes in the m6A and m5C methylation systems contribute to neurocognitive disorders. Early studies first identified mutations within FmR1 to cause intellectual disability Fragile X syndromes several years before FmR1 was identified as an m6A RNA reader protein. Subsequently, familial mutations within the m6A writer gene mETTL5, m5C writer genes NSUN2, NSUN3, NSUN5, and NSUN6, as well as THOC2 and THOC6 that form a protein complex with the m5C reader protein ALYREF, were recognized to cause intellectual development disorders. Similarly, differences in expression of the m5C writer and reader effector proteins, NSUN6, NSUN7, and ALYREF in brain tissue are indicated in individuals with Alzheimer’s disease, individuals with a high neuropathological load or have suffered traumatic brain injury. Likewise, an abundance of m6A reader and anti-reader proteins are reported to change across brain regions in Lewy bodies diseases, Alzheimer’s disease, and individuals with high cognitive reserve. m6A-modified RNAs are also reported significantly more abundant in dementia with Lewy bodies brain tissue but significantly reduced in Parkinson’s disease tissue, whilst modified RNAs are misplaced within diseased cells, particularly where synapses are located. In parahippocampal brain tissue, m6A modification is en

关键词： 5-methylcytosine methylation Alzheimer's disease cognitive diseases epitranscriptomics intellectual disability Lewy body diseases N6 adenosine RNA modification

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Detailed analysis of the relativistic configuration of Bardeen anisotropic spheres in modified f(G)gravity

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Communications in Theoretical Physics 2024年第6期76卷 45-56页

作者： Adnan malik Ayesha Almas Tayyaba Naz Rubab manzoor m z Bhatti School of mathematical Sciences Zhejiang Normal UniversityJinhuaZhejiangChina Department of mathematics University of Management and TechnologySialkot CampusLahorePakistan National University of Computer and Emerging Sciences Lahore CampusPakistan Department of mathematics University of Management and TechnologyJohar Town CampusLahore 54782Pakistan Department of mathematics University of the PunjabQuaid-i-Azam CampusLahore-54590Pakistan

The aim of this work is to investigate anisotropic compact objects within the framework of f(G)modified theory of *** our present work,we utilize Krori-Barua metrics,i.e.,λ(r)=Xr^(2)+Y andβ(r)=zr^(2).We use some matching conditions of spherically symmetric spacetime with Bardeen's model as an exterior ***,we establish some expressions of energy density and pressure components to analyze the stellar configuration of Bardeen compact stars by assuming viable f(G)*** examine the energy conditions for different stellar structures to verify the viability of our considered ***,we also investigate some other physical features,such as equilibrium condition,equation of state parameters,adiabatic index,stability analysis,mass function,surface redshift,and compactness factor,*** is worthwhile to mention here for the current study that our stellar structure in the background of Bardeen's model is more viable and stable.

关键词： Bardeen compact stars f(G)modified gravity Krori-Barua potential

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Selection criteria of mPOB-Angola germplasm collection for yield improvement of the oil palm

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Oil Crop Science 2024年第1期9卷 20-28页

作者： A.Norziha z.zamri Y.zulkifli A.m.Fadila m.marhalil malaysian Palm Oil Board 6Persiaran InstitusiBandar BaruBangi43000KajangSelangorMalaysia Institute of System Biology Universiti Kebangsaan Malaysia43600BangiSelangorMalaysia

Oil palm germplasm collected from Angola,Africa in 1991 were subjected to genetic variability potential *** collection was planted in the form of open-pollinated families as trials at the malaysian Palm Oil Board(mPOB)Kluang Research Station,Johor,malaysia,in *** palms from 52 families and tenera palms from 44 families of mPOB-Angola were evaluated for their bunch yield and bunch quality *** objectives of this study were to determine the genetic variability among the families and performance of mPOB-Angola germplasm for yield *** analysis of variance(ANOVA)revealed highly significant differences between the dura and tenera families for most of the traits,suggesting the presence of high genetic variability,which is essential for breeding *** the duras,family AGO 02.02 displayed the best yield performance,with a high fresh fruit bunch,oil yield and total economic product at 240.40,29.46 and 37.93 kg palm^(-1)year^(-1),*** for the teneras,family AGO 03.04 recorded the highest FFB yield and oil yield at 249.25 and 45.22 kg palm^(-1)year^(-1),*** that,several families with big fruit sizes or producing a mean fruit weight of 14-17 g were also *** dura and tenera from AGO 01.01 recorded the highest oil to bunch(O/B)of 17.76%and 28.65%,*** findings will facilitate the selection of palms from the mPOB-Angola germplasm for future breeding programmes.

关键词： Oil palm Germplasm Genetic variability Heritability Yield improvement

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Greatly enhanced corrosion/wear resistances of epoxy coating for mg alloy through a synergistic effect between functionalized graphene and insulated blocking layer

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Journal of magnesium and Alloys 2024年第1期12卷 332-344页

作者： z.Y.Xue X.J.Li J.H.Chu m.m.Li D.N.zou L.B.Tong School of metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China State Key Laboratory of Advanced Design and manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

The poor corrosion and wear resistances of mg alloys seriously limit their potential applications in various *** conventional epoxy coating easily forms many intrinsic defects during the solidification process,which cannot provide sufficient *** the current study,we design a double-layer epoxy composite coating on mg alloy with enhanced anti-corrosion/wear properties,via the spin-assisted assembly *** outer layer is functionalized graphene(FG)in waterborne epoxy resin(WEP)and the inner layer is Ce-based conversion(Ce)*** FG sheets can be homogeneously dispersed within the epoxy matrix to fill the intrinsic defects and improve the barrier *** Ce film connects the outer layer with the substrate,showing the transition *** corrosion rate of Ce/WEP/FG composite coating is 2131 times lower than that of bare mg alloy,and the wear rate is decreased by~90%.The improved corrosion resistance is attributed to the labyrinth effect(hindering the penetration of corrosive medium)and the obstruction of galvanic coupling *** synergistic effect derived from the FG sheet and blocking layer exhibits great potential in realizing the improvement of multi-functional integration,which will open up a new avenue for the development of novel composite protection coatings of mg alloys.

关键词： mg alloy Functionalized graphene Epoxy coating Corrosion/wear resistance Blocking layer

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Rational molecular design of efficient yellow-red dendrimer TADF for solution-processed OLEDs: a combined effect of substitution position and strength of the donors

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Science China Chemistry 2024年第5期67卷 1613-1623页

作者： Changfeng Si Dianming Sun Tomas matulaitis david B.Cordes Alexandra m.z.Slawin Eli zysman-Colman Organic Semiconductor Centre EaStCHEM School of ChemistryUniversity of St AndrewsSt AndrewsKY169STUK

The development of high-performance solution-processed red organic light-emitting diodes(OLEDs) remains a challenge,particularly in terms of maintaining efficiency at high luminance. Here, we designed and synthesized four novel orange-red thermally activated delayed fluorescence(TADF) dendrimers that are solution-processable: 2GCz BP, 2DPACz BP, 2FBP2GCz and 2FBP2DPACz. We systematically investigated the effect of substitution position and strength of donors on the optoelectronic properties. The reverse intersystem crossing rate constant(kRISC) of the emitters having donors substituted at positions 11and 12 of the dibenzo[a,c]phenazine(BP) is more than 10-times faster than that of compounds substituted having donors substituted at positions 3 and 6. Compound 2DPACz BP, containing stronger donors than 2GCz BP, exhibits a red-shifted emission and smaller singlet-triplet energy splitting, ΔE_(ST), of 0.01 e V. The solution-processed OLED with 10 wt% 2DPACz BP doped in m CP emitted at 640 nm and showed a maximum external quantum efficiency(EQE_(max)) of 7.8%, which was effectively maintained out to a luminance of 1,000 cd m-2. Such a device's performance at relevant display luminance is among the highest for solution-processed red TADF OLEDs. The efficiency of the devices was improved significantly by using 4Cz IPN as an assistant dopant in a hyperfluorescence(HF) configuration, where the 2DPACz BP HF device shows an EQEmaxof 20.0% at λEL of 605 nm and remains high at 11.8% at a luminance of 1,000 cd m-2, which makes this device one of the highest efficiency orange-to-red HF SP-OLEDs to date.

关键词： thermally activated delayed fluorescence solution-processing red OLEDs dibenzo[a,c]phenazine dendrimers

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Four Late-type Galaxies with Double Radio Lobes and Properties of Such Galaxies

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Research in Astronomy and Astrophysics 2024年第4期24卷 84-90页

作者： z.S.Yuan X.Y.Gao z.L.Wen J.L.Han National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China CAS Key Laboratory of FAST National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China

The triggering mechanism for radio lobes from late-type galaxies is not fully *** samples are desired for a thorough investigation and *** utilizing the optical data from the newly released dark Energy Spectroscopic Instrument imaging surveys and the radio sources from the NRAO VLA Sky Survey and the Faint Images of the Radio Sky at Twenty-centimeter,we identify four Late-type Galaxies with double Radio Lobes(La GRLs):J0217-3645,J0947+6220,J1412+3723 and J1736+*** previously known La GRLs,we confirm the correlation between radio power P_(1.4GHz)and stellar mass m_(*)of host ***(25/35)La GRLs belong to the blue cloud galaxies,while the newly identified cases in this work are located within the region of the red *** find a clear correlation between the differential radio power,i.e.,the offset from the P_(1.4GHz)-m_(*)relation,and the galaxy color,indicating that bluer galaxies at a fixed m_(*)tend to host more powerful radio ***,the majority(31/36)of La GRLs are either located in a galaxy group or displaying a disturbed *** suggest that all of the galaxy mass,color and surrounding environment could play important roles in triggering radio lobes in late-type galaxies.

关键词： galaxies:active galaxies:jets galaxies:spiral radio continuum:galaxies

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Fast efficient photon deceleration in plasmas by using two laser pulses at different frequencies

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matter and Radiation at Extremes 2024年第3期9卷 11-18页

作者： Y.X.Wang X.L.zhu S.m.Weng P.Li X.F.Li H.Ai H.R.Pan z.m.Sheng Key Laboratory for Laser Plasmas(moe) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghai 200240China Research Center of Laser Fusion of China Academy of Engineering Physics MianyangSichuan 621900China State key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Tsung-dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China

The generation of ultrashort high-power light sources in the mid-infrared(mid-IR)to terahertz(THz)range is of interest for applications in a number of fields,from fundamental research to biology and *** conventional laser technology,photon deceleration in plasma wakes provides an alternative approach to the generation of ultrashort mid-IR or THz ***,we present a photon deceleration scheme for the efficient generation of ultrashort mid-IR or THz pulses by using an intense driver laser pulse with a relatively short wavelength and a signal laser pulse with a relatively long *** signal pulse trails the driver pulse with an appropriate time delay such that it sits at the front of the second wake bubble that is driven by the driver *** to its relatively long wavelength,the signal pulse will be subjected to a large gradient of the refractive index in the plasma wake ***,the photon deceleration in the plasma wake becomes faster and more efficient for signal pulses with longer *** greatly enhances the capacity and efficiency of photon deceleration in the generation of ultrashort high-power light sources in the long-wavelength IR and THz spectral ranges.

关键词： laser ultrashort photon

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