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recent advances in breathable electronics

Nano research 2023年第3期16卷 4130-4142页

作者： zhuocheng Yan Jian Xiong Bin wang Min Gao Guangqiang Yin Tao Hu Taisong Pan Xinzhong wang Yuan Lin Department of Electronic Communication and Technology Shenzhen Institute of Information TechnologyShenzhen 518172China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 610054China School of Information and Software Engineering University of Electronic Science and Technology of ChinaChengdu 610054China Engineering Cooperation on Applied Medicine research Center University of Electronic Science and Technology of ChinaChengdu 610054China

The successful implementation of bioelectronic devices attached to living organism hinges on a number of material and device characteristics,including not only electrical and mechanical performances to gather physiological signals from living organism thus enabling status monitoring,but also permeability or breathability for gas/nutrient exchange between living organisms and surroundings to ensure minimum perturbation of the intrinsic biological ***,most bioelectronic devices built on planar polymeric substrates,such as polydimethylsiloxane(PDMS),polyurethane(PU),and polyimide(PI),lack efficient gas permeability,which may hinder the emission of volatile compounds from the surface of living organism,affecting the natural metabolism and reducing the comfort of ***,achieving permeability or breathability in bioelectronic devices is a significant ***,the devices made of gas-permeable materials with porous structures,that combine electronic components with daily garments,such as fibric and textile,offer exciting opportunities for breathable *** this review,several types of gas-permeable materials with their synthesis and processing routes are ***,two methods for measuring water vapor transmission rate of materials are discussed in ***,recent progress in the use of gaspermeable materials for the applications of plant-and skin-attached electronics is summarized systematically.

关键词： breathability gas permeability porous sponge foam nano materials plant electronics wearable electronics

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Electronic tattoos based on large-area Mo2C grown by chemical vapor deposition for electrophysiology

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Nano research 2023年第3期16卷 4100-4106页

作者： Shiyu wang Xin wang Weifeng zhang Xiaohu Shi Dekui Song Yan zhang Yan zhao zihan zhao Nan Liu Beijing Graphene Institute Beijing 100094China Beijing Key Laboratory of Energy Conversion and Storage Materials College of ChemistryBeijing Normal UniversityBeijing 100875China

Tattoo electronics has attracted intensive interest in recent years due to its comfortable wearing and imperceivable sensing,and has been broadly applied in wearable healthcare and human-machine ***,the tattoo electrodes are mostly composed of metal films and conductive ***-dimensional(2D)materials,which are superior in conductivity and stability,are barely studied for electronic ***,we reported a novel electronic tattoo based on large-area Mo_(2)C film grown by chemical vapor deposition(CVD),and applied it to accurately and imperceivably acquire on-body electrophysiological signals and interface with ***-quality Mo_(2)C film was obtained via optimizing the distribution of gas flow during CVD *** to the finite element simulation(FES),bottom surface of Cu foil covers more stable gas flow than the top surface,thus leading to more uniform Mo_(2)C *** resulting Mo_(2)C film was transferred onto tattoo paper,showing a total thickness of~3μm,sheet resistance of 60-150Ω/sq,and skin-electrode impedance of~5×10^(5)Ω.Such thin Mo_(2)C electronic tattoo(MCET in short)can form conformal contact with skin and accurately record electrophysiological signals,including electromyography(EMG),electrocardiogram(ECG),and electrooculogram(EOG).These body signals collected by MCET can not only reflect the health status but also be transformed to control the robotics for human-machine interface.

关键词： electronic tattoo Mo2C film gas flow chemical vapor deposition electrophysiological signals

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Prevalence of plasmid mediated bla_(TEM-1) and bla_(CTX-M-15) type extended spectrum beta-lactamases in patients with sepsis

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Asian Pacific Journal of Tropical Medicine 2012年第2期5卷 98-102页

作者： Shahzad F Haque Saeedut-z Ali Mohammed TP Asad U Khan Department of Medicine J.N.Medical CollegeAligarhIndia Interdisciplinary Biotechnology Unit AMUAligarh Muslim UniversityAligarhIndia Department of Medicine J.N.Medical College.AligarhIndia

Objective:To characterize the bacterial pathogens in patients having gram negative septicaemia. Further,to evaluate the antimicrobial resistance and underlying molecular mechanisms in these ***:A total number of 70 cases of gram negative sepsis were included in this prospective,open labeled,observational *** methods for isolation and identification of bacteria were *** susceptibility and ESBL testing was performed by the standard disc diffusion *** amplification was performed to identify blaCTX-M,blaSHVand blaTEM type *** experiments were performed to show resistant marker transfer. results:The most prevalent isolates Escherichia coli（***） 58.6%,Klebsiella Spp.32.9%and Pseudomonas 8.6%,were resistant to most of the antimicrobials including cefazolin,ceftriaxone, cefuroxime,ampicillin and co-trimoxazole but sensitive to imipenem and *** and MBL production was seen 7.3%and 12.2%of *** isolates *** isoaltes were found to have blaCTX-M-15 and two of them also showed blaTEM-1 type ***, none of them showed blaSHV.Conjugation experiments using J-53 cells confirmed these resistant markers as plasmid ***:This work highlights the molecular epidemiology of escalating antimicrobial resistance and likely switch over of blaCTX-M-15 type extended spectrum beta-lactamases by blaTEM type ESBLs in ***,the antimicrobial resistance by horizontal gene transfer was predominant among Enterobacteraceae in the community setting.

关键词： Gram negative sepsis ESBL Antimicrobial resistance

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急性前循环大血管闭塞性脑梗死桥接治疗和单纯机械取栓治疗的临床疗效

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黑龙江医学 2024年第2期48卷 156-158页

作者：王晓丽秦晋辉南阳市第二人民医院脑血管介入科河南南阳473000

目的:比较桥接治疗和单纯机械取栓治疗在急性前循环大血管闭塞性脑梗死中的临床疗效。方法:选取2021年1月—2022年1月南阳市第二人民医院脑血管介入科收治的50例急性前循环大血管闭塞性脑梗死患者作为研究对象,根据手术方案不同,分成桥... 详细信息

目的:比较桥接治疗和单纯机械取栓治疗在急性前循环大血管闭塞性脑梗死中的临床疗效。方法:选取2021年1月—2022年1月南阳市第二人民医院脑血管介入科收治的50例急性前循环大血管闭塞性脑梗死患者作为研究对象,根据手术方案不同,分成桥接组(n=25)和单纯机械取栓组(n=25)。比较血管再通情况、取栓相关指标、神经功能恢复情况、预后情况、并发症发生率。结果:两组患者血管再通情况、血管再通等级比较,差异无统计学意义(z=-0.623,P>0.05)。两组患者取栓次数和术后再灌注情况比较,差异无统计学意义(t=0.244;χ^(2)=0.095,P>0.05)。手术后,两组患者美国国立卫生研究院卒中量表(NIHSS)、入院时改良rankin(m rS)评分比较,差异无统计学意义(t=0.034、0.415,P>0.05)。单纯机械取栓组患者并发症发生率情况低于桥接组,差异有统计学意义(χ^(2)=4.153,P<0.05)。结论:手术治疗急性前循环大血管闭塞性脑梗死,选择桥接治疗和单纯机械取栓治疗均有很好的临床疗效,疗效相当。单纯机械取栓能够降低术中出血转化发生率,取得理想预后。

关键词：急性前循环大血管闭塞性脑梗死桥接单纯机械取栓疗效

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High-performance triboelectric nanogenerator based on zrB_(2)/polydimethylsiloxane for metal corrosion protection

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矿物冶金与材料学报:英文版 2023年第10期30卷 1957-1964页

作者： Xiucai wang Naijian Hu Jia Yang Jianwen Chen Xinmei Yu Wenbo zhu Chaochao zhao Ting wang Min Chen School of Materials Science and Hydrogen Energy Guangdong Key Laboratory for Hydrogen Energy TechnologiesFoshan UniversityFoshan 528000China School of Electronic and Information Engineering Foshan UniversityFoshan 528000China Mechatronics Engineering and Automation College Foshan UniversityFoshan 528200China Department of Biomedical Engineering School of MedicineFoshan UniversityFoshan 528225China Guangdong Provincial Key Laboratory of Electronic Functional Materials and Devices Huizhou UniversityHuizhou 516001China

Metal corrosion causes billions of dollars of economic losses *** a smart and new energy-harvesting device,triboelectric nanogenerators(TENGs)can convert almost all mechanical energy into electricity,which leads to great prospects in metal corrosion prevention and cathodic *** this work,flexible TENGs were designed to use the energy harvested by flexible polydimethylsiloxane(PDMS)films with zrB_(2)nanoparticles and effectively improve the dielectric constant by incorporating zrB_(2).The open-circuit voltage and short-circuit current were 264 V and 22.9μA,respectively,and the power density of the TENGs reached 6 W·m^(-2).Furthermore,a selfpowered anti-corrosion system was designed by the rectifier circuit integrated with TENGs,and the open-circuit potential(OCP)and Tafel curves showed that the system had an excellent anti-corrosion effect on carbon ***,the system has broad application prospects in fields such as metal cultural relics,ocean engineering,and industry.

关键词： zrB_(2) triboelectric nanogenerator self-powered corrosion protection

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近年来台湾地区建筑科学研究进展——基于中国台湾《建筑学报》视角的统计分析

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艺术与设计（理论版） 2024年第2期 33-36页

作者：叶文欣王彬牛倩福建理工大学建筑与城乡规划学院福州350118

建筑学是一门涉及设计、工程、理论和技术等方面的复杂学科。随着时间推移,建筑学研究主题亦随之变化。文章以中国台湾《建筑学报》为数据样本,选取作者、关键词、学科交叉等数据进行统计分析,采用Ucinet软件生成领域研究成果图谱,将主... 详细信息

建筑学是一门涉及设计、工程、理论和技术等方面的复杂学科。随着时间推移,建筑学研究主题亦随之变化。文章以中国台湾《建筑学报》为数据样本,选取作者、关键词、学科交叉等数据进行统计分析,采用Ucinet软件生成领域研究成果图谱,将主要学术力量、热点主题及研究演变可视化,从而探析学科领域发展趋势。研究发现台湾地区建筑学科在合作度方面呈逐步攀升趋势;在关键词方面呈与社会需求紧密结合态势;在学科交叉方面呈现相对融合状态。

关键词：作者合作度共词网络研究热点研究进展中国台湾《建筑学报》

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Construction of defect-containing UiO-66/MoSe_(2) heterojunctions with superior photocatalytic performance for wastewater treatment and mechanism insight

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Frontiers of Chemical Science and Engineering 2023年第4期17卷 449-459页

作者： Xiao Han Xiaoxuan wang Jiafang wang Yingjie Xie Cuiwei Du Chongfei Yu Jinglan Feng Jianhui Sun Shuying Dong School of Environment Henan Normal UniversityXinxiang 453007China Key Laboratory for Yellow river and Huai river Water Environmental and Pollution Control Ministry of EducationXinxiang 453007China

Metal-organic frameworks are recognized as promising multifunctional materials,especially metal-organic framework-based photocatalysts,which are considered to be ideal photocatalytic ***,a new type of UiO-66/MoSe_(2) composite was prepared using the solvothermal *** optimum composite was selected by adjusting the mass ratio of UiO-66 and MoSe_(2).X-ray diffraction analysis showed that the mass ratio influenced the crystal plane exposure rate of the composite,which may have affected its photocatalytic *** composite is composed of ultra-thin flower-like MoSe_(2) that wrapped around cubic UiO-66,a structure that increases the abundance of active sites for reactions and is more conducive to the separation of *** photocatalytic properties of the composite were evaluated by measuring the degradation rate of rhodamine B and the catalyst’s ability to reduce Cr(VI)-containing wastewater under visible light *** B was decolorized completely in 120 min,and most of the Cr(VI)was reduced within 150 *** photochemical mechanism of the complex was studied in *** existence of Mo^(6+)and oxygen vacancies,in addition to the z-type heterojunction promote the separation of electrons and holes,which enhances the photocatalytic effect.

关键词： UiO-66 MoSe_(2) photocatalysis dye-containing wastewater heavy metal wastewater oxygen vacancies

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职业教育中的教学资源库设计

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集成电路应用 2024年第4期41卷 88-89页

作者：苏保稳王天永鄄城县职业中等专业学校山东274600

阐述机电技术应用课程中的技能教学资源库设计,探讨教学资源库的优化利用。通过建设教学资源库,有利于整合各种教学资源,提高教学效率,培养学生的实践技能与创新能力。

关键词：职业教育机电技术技能教学资源库

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湿润烧伤膏联合康复新液在低位肛周脓肿根治术后创面中的应用效果分析

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中国烧伤创疡杂志 2024年第5期36卷 405-409页

作者：王小国陈康清耒阳市中医医院肛肠外科湖南耒阳421800

目的分析湿润烧伤膏联合康复新液在低位肛周脓肿根治术后创面中的应用效果。方法选取2022年4月至2023年10月耒阳市中医医院收治的74例拟行低位肛周脓肿根治术治疗的患者作为研究对象,按照术后创面不同换药方法将其分为研究组(38例)与对... 详细信息

目的分析湿润烧伤膏联合康复新液在低位肛周脓肿根治术后创面中的应用效果。方法选取2022年4月至2023年10月耒阳市中医医院收治的74例拟行低位肛周脓肿根治术治疗的患者作为研究对象,按照术后创面不同换药方法将其分为研究组(38例)与对照组(36例),研究组患者低位肛周脓肿根治术后创面采用湿润烧伤膏联合康复新液治疗,对照组患者低位肛周脓肿根治术后创面采用凡士林联合康复新液治疗,对比观察两组患者术后创面水肿、分泌物、肉芽组织生长与疼痛情况以及血清炎症因子水平、创面缩小率与创面愈合时间。结果术后7、14 d,研究组患者创面水肿及分泌物评分均明显低于对照组(术后7 d:z=-3.459、-3.252,P=0.001、0.001;术后14 d:z=-3.239、-3.514,P=0.001、Pz=-2.944、-3.022,P=0.003、0.003;术后14 d:z=-2.597、-2.705,P=0.009、0.007;术后21 d:z=-3.032、-2.106,P=0.002、0.035);术后5 d,研究组患者血清C反应蛋白(CrP)、降钙素原(PCT)水平均明显低于对照组(z=-2.480、-2.120,P=0.013、0.034);术后第21天,研究组患者创面缩小率明显大于对照组(z=-2.689,P=0.007);研究组患者创面愈合时间明显短于对照组(z=-2.414,P=0.016)。结论与凡士林联合康复新液换药治疗相比,湿润烧伤膏联合康复新液更能有效促进低位肛周脓肿根治术后创面水肿吸收,减少创面渗出,减轻创面疼痛及炎症反应程度,加快肉芽组织生长及创面愈合,临床应用价值更高。

关键词：湿润烧伤膏康复新液肛周脓肿术后创面水肿疼痛

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Effective and persistent antitumor activity of HEr2-directed CAr-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo

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Protein & Cell 2018年第10期9卷 867-878页

作者： Yanjing Song Chuan Tong Yao wang Yunhe Gao Hanren Dai Yelei Guo Xudong zhao Yi wang zizheng wang Weidong Han Lin Chen Department of General Surgery Chinese PLA General Hospital Beijing 100853 China Medical School of Chinese PLA Beijing 100853 China Bio-therapeutic Department Chinese PLA General Hospital Beijing 100853 China Molecular & Immunology Department Chinese PLA General Hospital Beijing 100853 China

Human epidermal growth factor receptor 2 （HEr2） pro- teins are overexpressed in a high proportion of gastric cancer （GC） cases and affect the maintenance of cancer stem cell （CSC） subpopulations, which are used as tar- gets for the clinical treatment of patients with HEr2- positive GC. Despite improvements in survival, numer- ous HEr2-positive patients fail treatment with trastuzu- mab, highlighting the need for more effective therapies. In this study, we generated a novel type of genetically modified human T cells, expressing a chimeric antigen receptor （CAr）, and targeting the GC cell antigen HEr2, which harbors the CD137 and CD3/; moieties. Our findings show that the expanded CArT cells, expressing an increased central memory phenotype, were activated by the specific recognition of HEr2 antigens in an MHC-in- dependent manner, and effectively killed patient-derived HEr2-positive GC cells. In HEr2-positive xenograft tumors, CArT cells exhibited considerably enhanced tumor inhibition ability, long-term survival, and homing totargets, compared with those of non-transduced T cells. The sphere-forming ability and in vivo tumorigenicity of patient-derived gastric cancer stem-like cells, expressing HEr2 and the CD44 protein, were also inhibited. Our results support the future development and clinical application of this adoptive immunotherapy in patients with HEr2-positive advanced GC.

关键词： chimeric antigen receptor HEr2 gastriccancer cancer stem cell CD137 immunotherapy

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