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h.patocardiorenal syndrome in liver cirrh.sis:Recognition of a new entity?

World Journal of Gastroenterology 2024年第2期30卷 128-136页

作者： h.nry h.L Wu Amina Rakish.va Arvind Ponnusamy Rajkumar Ch.nnadurai Renal Research Kolling Institute of Medical ResearchRoyal North Shore Hospital&The University of SydneySt.Leonards(Sydney)2065New South WalesAustralia Department of Cardiology City Cardiological CenterAlmaty 050000Kazakhstan Department of Renal Medicine Royal Preston HospitalPreston PR29HTUnited Kingdom Donal O’Donogh.e Renal Research.Centre&Department of Renal Medicine Northern Care Alliance National Health Service Foundation TrustSalford M68HDUnited Kingdom

Emerging evidence and perspectives h.ve pointed towards th. h.art playing an important role in h.patorenal syndrome(h.S),outside of conventional understanding th.t liver cirrh.sis is traditionally considered th. sole origin of a cascade of path.ph.siological mech.nisms directly affecting th. kidneys in th.s *** th. absence of establish.d h.art disease,cirrh.tic cardiomyopath. may occur more frequently in th.se with.liver cirrh.sis and kidney *** is a specific form of cardiac dysfunction ch.racterized by blunted contractile responsiveness to stress stimuli and altered diastolic relaxation with.electroph.siological *** th. clinical description of th.se potential cardiac-related complications of th. liver,th. role of th. h.art h.s traditionally been an overlooked aspect of circulatory dysfunction in *** from a ph.siological sense,temporality(prior onset)of cardiorenal interactions in h.S and positive effects stemming from portosystemic sh.nting demonstrated an important role of th. h.art in th. development and progression of kidney dysfunction in cirrh.tic *** th.s review,we discuss current concepts surrounding h.w th. h.art may influence th. development and progression of h.S,and th. role of systemic inflammation and endoth.lial dysfunction causing circulatory dysfunction with.n th.s *** temporality of h.art and kidney dysfunction in h.S will be *** a subgroup of patients wh. receive portosystemic sh.nting,th. dynamics of cardiorenal interactions following treatment is *** research.to determine th. unknowns in th.s topic is anticipated,h.pefully to furth.r clarify th. intricacies surrounding th. liver-h.art-kidney connection and improve strategies for management.

关键词： h.patorenal syndrome Cardiorenal syndrome Cirrh.sis Cardiac dysfunction Circulatory dysfunction

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Efficiency of Bio-Fertilizing as One of th. Natural Alternatives to Improve th. Growth.of Kh.ya senegalensis and Swietenia mah.goni Trees and for Sustainability

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Agricultural Sciences 2024年第2期15卷 292-310页

作者： Safaa A. S. Gh.rab Nash.a h. Moh.med Nader A. El-Sh.nh.rey Nabal S. El-Sh.h.t Amr R. Rabie Forestry and Timber Trees Department Horticulture Research Institute Agricultural Research Center Ismailia Egypt Forestry and Timber Trees Department Horticulture Research Institute Agricultural Research Center Alexandria Egypt Botanical Gardens Department Horticulture Research Institute Agricultural Research Center Alexandria Egypt Forestry and Timber Trees Department Horticulture Research Institute Agricultural Research Center Giza Egypt

A field experiment was carried out at Ismailia Research.Station, Ismailia Governorate from 2020-2022 to improve th. growth.of Kh.ya senegalensis and Swietenia mah.goni by using a combination of mineral fertilizer (NPK) and biological fertilizer (Azotobacter ch.oococcum, Bacillus megath.rium, and Bacillus circulant) as recommended dose under new sandy soils conditions. Split plot designed with.four treatments (Control, (50% Mineral fertilizer (M.) + 50% Biological fertilizer (Bio.)), 100% M. and 100% Bio.) of each.species. Vegetative growth. leaf area, tree biomass, stored carbon, basal area, tree volume, and in th. soil both.of microbial account and mineral content were determined. Th. experimental results sh.wed no significant differences between studied species among th. most studied parameters except for Kh.ya senegalensis wh.ch.gave th. h.gh.st significant difference in root biomass and below-stored carbon th.n Swietenia mah.goni. Evidently, th. h.gh.st significant growth.parameters were 100% mineral fertilizer followed by (50% M. + 50% Bio.) as compared with.control. No significant difference between 100% M. and (50% M. + 50% Bio.) of sh.ot dry biomass (15.19 and 12.02 kg, respectively) and above-stored carbon (0.28 and 0.22 Mt, respectively). Microbial account and mineral content in soil were improved after cultivation of tree species compared to before planting and control, especially with.50% mineral fertilizer and 50% bio-fertilizer treatment. In conclusion, a treatment containing 50% mineral fertilizer and 50% bio-fertilizer h.s led to th. ideal Kh.ya senegalensis and Swietenia mah.goni growth.in sandy soil for ch.aper and sustainable.

关键词： Kh.ya senegalensis Swietenia mah.goni Mineral Fertilizer Bio-Fertilizer Growth.Parameters Tree Biomass Stored Carbon Sustainable

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Adult Urological Cancers at Zinder National h.spital

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Open Journal of Urology 2024年第5期14卷 267-276页

作者： h.lidou Maazou Manzo M. S. Ousmane Ch.ibou Soumana Abdoulaye Kodo Idrissa Seriba Abdoulrazak R. h. Zakou Soumana Amadou Department of Urology University of Zinder Zinder Niger Department of Urologie University of Niamey Niamey Niger Department of Mé dicale Oncology National H&#244pital of Zinder Zinder Niger Department of Anatomy Path.logy Universit&#233 of Zinder Zinder Niger

Th. aim of th.s study was to present th. epidemiological, clinical and th.rapeutic aspects of adult urological cancers in th. department of urology at Zinder National h.spital. Patients and Meth.ds: Th.s was a cross-sectional study of adult primary urologic cancers during th. period of January 2019 to December 2023. Data were obtained from th. record of patients admitted to urology, and th. medical oncology department. Th. parameters studied were;frequency, age, sex, urogenital distribution, anatomopath.logical type, and th.rapeutic aspects. Data were recorded on Excel 2013 and analyzed with.Epi-info version 7.2.5. Results: Epidemiology: About 289 cancers were diagnosed th.ough.6017 consultations during th. period, corresponding to 4.80% of urological path.logies: prostate cancer (n = 221;76.47%), bladder cancer (n = 46;15.92%), kidney cancer (n = 13;04.5%), testis cancer (n = 09;03.11%). Median age of patients was 50.42 years. Prostate cancer: was Adenocarcinoma in 100% (n = 221) with.Gleason scores > 7 (77.83%) and prostatique specific antigen (PSA) > 20 ng/ml in 90.04%. Extension evaluation 134 cases (60.63%). Treatment was ch.rurgical castration in (62.44%) and resistance to castration appeared between 8 and 11 month.. h.spital mortality for prostate cancer was 16.29%. Bladder cancer was found in 46 cases with.Sex ratio 7/1. Cystoscopy was performed for all. h.stology revealed squamous cell carcinoma (n = 41;89.13%), and (n = 5;10.87%) uroth.lial. Endoscopic resection performed (n = 14;30.43%). Kidney cancers were 13 cases (10 men, 03 women). Neph.ectomy was performed in (n = 8;61.54%) cases and h.stology revealed renal cell cancer in 76.92%. Testicular cancers were diag 09 cases. h.story of cryptorch.dism was found in 4 cases, 4-year infertility in 3 cases. Orch.dectomy was done in all cases. Ch.moth.rapy in 3 cases. Conclusion: urological cancers are frequent, dominated by prostate cancer. Th. endemicity of bilh.rziasis h.s increased squamous cell carcinoma. T

关键词： Urologic Cancers Epidemiology h.stology Zinder

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Pelleting and particle size reduction of corn increase net energy and digestibility of fiber,protein,and fat in corn-soybean meal diets fed to group-h.used pigs

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Journal of Animal Science and Biotech.ology 2024年第4期15卷 1751-1760页

作者： Su A Lee Diego A.Rodriguez Ch.d B.Paulk h.ns h.Stein Department of Animal Sciences University of IllinoisUrbanaIL 61801USA Department of Grain Sciences and Industry Kansas State UniversityManhattanKS 66506USA

Background Reduction of th. particle size of corn increases energy digestibility and concentrations of digestible and metabolizable *** may also reduce particle size of grain,but it is not known if th.re are interactions between particle size reduction and *** objective of th.s experiment was to test th. h.poth.sis th.t particle size reduction and pelleting,separately or in combination,increase N balance,apparent total tract digestibility(ATTD)of fiber and fat,and net energy(NE)in corn-soybean meal diets fed to group-h.used *** Six corn-soybean meal-based diets were used in a 3×2 factorial design with.3 particle sizes of corn(i.e.,700,500,or 300μm)and 2 diet forms(i.e.,meal or pelleted).Pigs were allowed ad libitum access to feed and ***-four castrated male pigs(initial weigh.:29.52 kg;standard diviation:1.40)were allotted to th. 6 diets using a 6×6 Latin square design with.6 calorimeter ch.mbers(i.e.,4 pigs/ch.mber)and 6 *** consumption and CO_(2)and Ch.(4)productions were measured during fed and fasting states and fecal and urine samples were *** Regardless of particle size of corn,th. ATTD of gross energy(GE),N,and acid-h.drolyzed eth.r extract(AEE),and th. concentration of NE were greater(Ph.n in meal *** of diet form,th. ATTD of GE,N,and AEE,and th. concentration of NE were increased(linear;Ph. particle size of corn,but th. increase was greater in meal diets th.n in pelleted diets(interaction;Ph.pelleting and reduction of corn particle size increased nutrient digestibility and NE,but increases were greater in meal diets th.n in pelleted diets.

关键词： Corn Digestibility Feed tech.ology Net energy Particle size Pelleting

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Low-carbon Development Path.of Ordos Based on LEAP Model

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h.anjing Kexue/Environmental Science 2024年第9期45卷 5097-5105页

作者： Yu Y.-W.-Q. Liu B. Zh. X.-h. Zh.ng J.-Y. Wang B.-h. Wang M.-P. Yang J.-G. Bai Y. Yang F.-Y. Sch.ol of Veh.cle and Mobility Tsinghua University Beijing 100084 China Ordos Carbon Neutral Research.and Application Co.，Ltd. Ordos 017004 China

To determine th. low-carbon development path.of Ordos，th.ee scenarios（baseline scenario，low carbon scenario，and enh.nced low carbon scenario）were constructed based on th. LEAP model to forecast th. energy demand and carbon emission in Ordos from 2020 to 2050 and to analyze th. contribution of various policy initiatives to reduce carbon emission. Th. results sh.wed th.t under th. enh.nced low carbon scenario，th. energy demand in Ordos peaked at 52 million tons of standard coal equivalent in 2025 and decreased to 40 million tons of standard coal equivalent in 2050，and carbon emissions peaked at 163 million tons in 2025 and decreased to 16 million tons in 2050，wh.ch.was 88% lower th.n th.t in 2020. Regarding emission reduction contribution，comparing th. baseline scenario and th. enh.nced low-carbon scenario，th. increase in renewable energy power generation installation，th. reduction in energy consumption of terminal energy use，and th. increase in terminal electrification rate contributed to th. emission reductions of 43%，25%，and 24%，respectively. Th. Ordos sh.uld vigorously develop renewable energy and make full use of th. rich.endowment of wind and ligh. resources；at th. same time，it sh.uld promote economic transformation and gradually increase th. proportion of h.gh.value-added and low-energy-consuming industries in th. industrial structure. For th. power sector，th. power generation structure sh.uld be adjusted. Traditional th.rmal power generation sh.uld be replaced by zero-carbon and low-carbon power generation tech.ologies. For th. industrial and transportation sectors，th. terminal electrification rate sh.uld be increased，and th. energy intensity sh.uld be reduced. © 2024 Science Press. All righ.s reserved.

关键词： carbon emission LEAP model Ordos City renewable energy generation scenario analysis

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Search.for production of dark fermion candidates in association with.h.avy neutral gauge boson decaying to dimuon in proton-proton collisions at√s=8 TeV using CMS open data

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Ch.nese Ph.sics C 2024年第4期48卷 6-13页

作者： Y.Mah.oud h.Abdallah.M.T.h.ssein S.Elgammal Centre for th.oretical ph.sics The British University in EgyptEgypt Ph.sics Department Faculty of ScienceCairo UniversityEgypt

In th.s study,we conducted a search.for dark matter using a part of th. data recorded by th. CMS experiment during run-I of th. Lh. in 2012 with.a center of mass energy of 8 TeV and an integrated luminosity of 11.6 fb−*** data were gath.red from th. CMS open *** matter,in th. framework of th. simplified model(mono-Z′),can be produced from proton-proton collisions in association with.a new h.poth.tical gauge boson,Z′.Th.s,th. search.was conducted in th. dimuon plus large missing transverse momentum *** bench.ark scenario of mono-Z′,wh.ch.is known as ligh. vector,was used for interpreting th. CMS open *** evidence of dark matter was observed,and exclusion limits were set on th. masses of dark matter and Z′at 95%confidence level.

关键词： dark matter large h.dron collider CMS open data search.for new ph.sics dark fermion

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Music as medicine for traumatic brain injury:a perspective on future research.directions

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Neural Regeneration Research 2024年第10期19卷 2105-2106页

作者： Anth.ny E.Kline Eleni h.Mosch.nas Corina O.Bondi Department of Ph.sical Medicine&Reh.bilitation University of PittsburghPittsburghPAUSA Safar Center for Resuscitation Research University of PittsburghPittsburghPAUSA Center for Neuroscience University of PittsburghPittsburghPAUSA Department of Critical Care Medicine University of PittsburghPittsburghPAUSA Center for th. Neural Basis of Cognition University of PittsburghPittsburghPAUSA Department of Psych.logy University of PittsburghPittsburghPAUSA Department of Neurobiology University of PittsburghPittsburghPAUSA

Traumatic brain injury(TBI) impacts 69 million individuals globally each.year and is a leading cause of death.and disability(Dewan et al.,2019).Th. majority of moderate-to-severe TBI survivors endure long-lasting disturbances in motor,cognitive,and affect th.t negatively impacts th.ir *** a pleth.ra of research.on ph.rmacological interventions for TBI h.s been conducted,none h.s translated to th. clinic,th.s advocating for th. evaluation of nonph.rmacological th.rapeutic approach.s th.t may increase translational success.

关键词： injury traumatic

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Integralinput-to-statestability ystemswith.malldelays Integral input-to-state stability of systems with.small delays

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Control Th.ory and Tech.ology 2024年第3期22卷 455-467页

作者： R.h.h.rsh. Nawarath.a Yuandan Lin Yuan Wang Department of Math.matical Sciences Florida Atlantic UniversityBoca RatonFL 33431USA

We consider h.w small delays affect th. integral-input-to-state stability(iss)property for a *** result is similar to th. input-to-state stability(Iss)result obtained in[1]:th. iss property will be preserved in a practical and semi-global manner if th. delay interval is small ***,since th. iss quantifies th. robust stability in terms of a generalized Li norm of th. inputs instead of a generalized Loo norm of th. inputs for th. Iss case,th. tech.iques and proofs for th. Iss case do not apply to th. iss case *** th. proofs in[1]are based on th. Lyapunov-Razumikh.n approach.our proofs are based on th. iss-Lyapunov functions for th. zero-delay *** addition to th. interest by its own in sh.wing h.w th. iss property is affected by small delays,th. result also serves to th. study of th. iss property for singularly perturbed systems.

关键词： Integral-input-to-state stability Nonlinear systems Small delays Lyapunov meth.d

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Role of marine natural products in th. development of antiviral agents against SARS‑CoV‑2:potential and prospects

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Marine Life Science & Tech.ology 2024年第2期6卷 280-297页

作者： D.P.Nagah.watta N.M.Liyanage Th.lina U.Jayawardena h.h.A.C.K.Jayawardh.na Seong‑h.n Jeong h.ung‑Jun Kwon You‑Jin Jeon Department of Marine Life Sciences Jeju National UniversityJeju 690-756Republic of Korea Department of Ch.mistry Biochemistry and PhysicsUniversitédu QuébecàTrois-RivièresTrois-RivièresQC G8Z 4M3Canada Marine Science Institute Jeju National UniversityJeju 63333Republic of Korea Functional Biomaterial Research.Center Korea Research Institute of Bioscience and BiotechnologyJeongeup-siRepublic of Korea

A novel coronavirus,known as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),h.s surfaced and caused global concern owing to its ***-CoV-2 is th. causative agent of coronavirus disease 2019;h.wever,it was only discovered at th. end of th. year and was considered a pandemic by th. World h.alth.***,th. develop-ment of novel potent inh.bitors against SARS-CoV-2 and future outbreaks is urgently *** naturally occurring bioactive substances h.ve been studied in th. clinical setting for diverse *** intricate infection and replication mech.nism of SARS-CoV-2 offers diverse th.rapeutic drug targets for developing antiviral medicines by employing natural products th.t are safer th.n synth.tic *** natural products(MNPs)h.ve received increased attention in th. development of novel drugs owing to th.ir h.gh.diversity and ***,th.s review article investigates th. infection and replication mech.nisms,including th. function of th. SARS-CoV-2 genome and ***,we h.gh.igh.ed anti-SARS-CoV-2 th.rapeutic intervention efforts utilizing MNPs and predicted SARS-CoV-2 inh.bitor design.

关键词： SARS-CoV-2 Marine natural products Drug targets Inh.bitors

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A vectorial model for th. nonlinear gradient force exerted on metallic Rayleigh.nanoparticles

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Ch.nese Optics Letters 2024年第2期22卷 207-213页

作者：朱政张聿全闵长俊 Aurèle J.LAdam h.Paul Urbach.袁小聪 Research.Center for h.manoid Sensing Research Institute of Intelligent SensingZhejiang LabHangzhou 311100China Nanoph.tonics Research.Center Institute of Microscale Optoelectronics&State Key Laboratory of Radio Frequency Heterogeneous IntegrationShenzhen UniversityShenzhen 518060China Optics Research.Group ImPhys DepartmentFaculty of Applied SciencesDelft University of TechnologyDelft 2628 CJThe Netherlands

Optical tweezers h.ve proved to be a powerful tool with.a wide range of *** gradient force plays a vital role in th. stable optical trapping of *** scalar meth.d is convenient and effective for analyzing th. gradient force in traditional optical ***,wh.n th. th.rd-order nonlinear effect of th. nano-object is stimulated,th. scalar meth.d cannot adequately present th. optical response of th. metal nanoparticle to th. external optical ***,we propose a th.oretical model to interpret th. nonlinear gradient force using th. vector *** combining th. optical Kerr effect,th. polarizability vector of th. metallic nanoparticle is derived.A quantitative analysis is obtained for th. gradient force as well as for th. optical potential *** vector meth.d yields better agreement with.reported experimental *** suggest th.t th.s meth.d could lead to a deeper understanding of th. ph.sics relevant to nonlinear optical trapping and binding ph.nomena.

关键词： gradient forces nonlinear effect metallic nanoparticles

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