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Detection of pancreatic cancer by indocyanine green-assisted fluorescence imaging in the first and second near-infrared windows

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Cancer Communications 2021年第12期41卷 1431-1434页

作者： Zhongqiang Li Zheng Li Alexandra Ramos J.Philip Boudreaux Ramcharan Thiagarajan yvette bren mattison Michael E.Dunham Andrew J McWhorter Qing Chen Jian Zhang Ji-Ming Feng Yanping Li Shaomian Yao Jian Xu Division of Electrical and Computer Engineering College of EngineeringLouisiana State UniversityBaton RougeLA 70803USA Department of Comparative Biomedical Science School of Veterinary MedicineLouisiana State UniversityBaton RougeLA 70803USA Department of Surgery School of MedicineLouisiana State University Health Science CenterNew OrleansLA 70112USA Department of Otolaryngology School of MedicineLouisiana State University Health Science CenterNew OrleansLA 70112USA Division of Computer Science&Engineering College of EngineeringLouisiana State UniversityBaton RougeLA 70803USA School of Environment and Sustainability University of SaskatchewanSaskatoonSK S7N 5C9Canada

Dear Editor,In the United States,pancreatic cancer is considered the fourth most common reason for cancer-related deaths;over 53%of patients are diagnosed at end-stage with a 5-year survival rate of less than 3%[1].Incomplete removal of all cancerous cells generally leads to local recurrence of pancreatic cancer[2].Thus,the detection of tumor margin status plays an essential role in the complete resection of pancreatic *** of the existing imaging modalities,like computed tomography and magnetic resonance imaging,are primarily used for preoperative planning;these modalities also have issues of bulky equipment,radiation concerns,and slow imaging speed[2].Thus,these modalities can neither provide an intraoperative diagnosis of cancer with high sensitivity and specificity nor be used to define tumor margins[3].

关键词： diagnosis specificity neither

Mechanics of rib deformation—Observations and monitoring in Australian coal mines

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International Journal of Mining Science and Technology 2019年第1期29卷 119-129页

作者： yvette Heritage SCT Operations Pty Ltd

The risk of fatalities from rib failure is still prevalent in the coal mining industry. This risk has prompted further research to be conducted on rib deformation in order to understand the mechanisms of rib failure,with the long-term objective being to improve rib support design. This paper presents the results of ACARP research project C25057, which investigated the mechanics and drivers of rib failure. The results of rib deformation monitoring at three different mines in Australia provide rib deformation characteristics for overburden depths ranging from 160 to 530 m. Monitoring includes deformation during development drivage conditions and during the longwall retreat abutment stress environment. The rib deformation monitoring covered three different seams: the Goonyella Middle Seam, Ulan Seam, and Bulli Seam in the Bowen Basin, Western Coalfield, and Southern Coalfield, respectively. The observed mechanisms driving the rib deformation ranged from bedding shear failure along weak claystone bands to vertical shear fractures to kinematic failures driven by shear failure dilation. The variation in mechanisms of rib failure, together with the seemingly consistent method of rib support design, prompts the question: what exactly is the role of rib support?

关键词： Coal Rib Deformation Monitoring Measurement

Octopamine enhances learning

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National Science Review 2024年第6期11卷 82-83页

作者： yvette E.Fisher Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute University of California

Across the animal kingdom, diverse monoamines actuate and modulate neural circuit function. However, measuring the rapid dynamics of these neuromodulators at cellular resolution has historically presented significant ... 详细信息

关键词： learning enhances octopamine

Impact of the COVID-19 pandemic on agricultural exports

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Journal of Integrative Agriculture 2020年第12期19卷 2937-2945页

作者： LIN Ben-xi Yu yvette ZHANG School of Economics Fujian Agriculture and Forestry UniversityFuzhou 350002P.R.China Department of Agricultural Economics Texas A&M UniversityCollege StationTX 77843USA

The COVID-19 outbreak has shocked the world’s economies in the year of *** this pandemic spreads around the globe,many experts feared that the global food supplies might start running short,especially if supply chains were ***-19 also added to the uncertainty of the business ***,it is critical to understand how COVID-19 pandemic affected global food supply and *** this study,we investigate the impact of COVID-19 on agricultural export companies in China using a unique firm-level survey *** found that although on average agricultural businesses experienced declines in the exports,exports of some agricultural products especially grain and oil held strong and even increased,implying the essential demand for staple food during the *** surprisingly,exports of medicinal herb also increased significantly during the ***,exports of goods such as edible fungus and horticultural products sharply *** results also showed that in general,impact of COVID-19 on smaller firms was more severe than that on larger *** results of this study can provide useful guidance and implications for agricultural businesses and policy makers on their COVID-19 mitigation efforts to navigate this global pandemic.

关键词： COVID-19 pandemic agricultural exports business survey international trade China

Sex hormones in the modulation of irritable bowel syndrome

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World Journal of Gastroenterology 2014年第10期20卷 2433-2448页

作者： Agata Mulak yvette Taché Muriel Larauche Department of Gastroenterology and Hepatology Wroclaw Medical University 50-556 Wroclaw Poland CURE:Digestive Diseases Research Center and Oppenheimer Family Center for Neurobiology of Stress Digestive Diseases Division Department of MedicineUniversity of California Los Angeles VA Greater Los Angeles Healthcare System Los Angeles CA 90073 United States

Compelling evidence indicates sex and gender differences in epidemiology, symptomatology, pathophysiology, and treatment outcome in irritable bowel syndrome (IBS). Based on the female predominance as well as the correlation between IBS symptoms and hormonal status, several models have been proposed to examine the role of sex hormones in gastrointestinal (GI) function including differences in GI symptoms expression in distinct phases of the menstrual cycle, in pre- and post-menopausal women, during pregnancy, hormonal treatment or after oophorectomy. Sex hormones may influence peripheral and central regulatory mechanisms of the brain-gut axis involved in the pathophysiology of IBS contributing to the alterations in visceral sensitivity, motility, intestinal barrier function, and immune activation of intestinal mucosa. Sex differences in stress response of the hypothalamic-pituitary-adrenal axis and autonomic nervous system, neuroimmune interactions triggered by stress, as well as estrogen interactions with serotonin and corticotropin-releasing factor signaling systems are being increasingly recognized. A concept of “microgenderome” related to the potential role of sex hormone modulation of the gut microbiota is also emerging. Significant differences between IBS female and male patients regarding symptomatology and comorbidity with other chronic pain syndromes and psychiatric disorders, together with differences in efficacy of serotonergic medications in IBS patients confirm the necessity for more sex-tailored therapeutic approach in this disorder.

关键词： Brain-gut axis Irritable bowel syndrome Microbiota Pain modulation Sex hormones

A combined 2D and 3D numerical modeling approach to provide adequate roof support in complex 3D excavations

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International Journal of Mining Science and Technology 2016年第1期26卷 169-174页

作者： Heritage yvette Stemp Craig SCT Operations Pry Ltd. Wollongong NSW 2500 Australia

Traditional methods for assessing effective roof support can be difficult to apply to complex three-dimensional excavations. Through worked examples,the approach of combined two-dimensional and three-dimensional numerical modeling has been shown to be successful in understanding mechanisms of rock failure for unique excavation geometries and geotechnical properties and,in turn,provides adequate roof support recommendations for complex three-dimensional excavations in Australian coal mines. An interactive approach of monitoring and model review during the excavation process is an important part of model support recommendations to ensure rock failure and deformation in the model are representative of actual conditions,to provide effective and practical controls.

关键词： 3D numerical modelingUnderground excavationsRoof supportRock failureUnderground storage bin

Nonvesicular trafficking of cholesterol by Aster proteins

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Life Metabolism 2023年第2期2卷 6-7页

作者： Dougall Norris yvette Aw Hongyuan Yang School of Biotechnology and Biomolecular Sciences University of New South WalesSydneyNSW2052Australia

In a recent article published in Nature Metabolism,Peter Tontonoz and colleagues found that the Aster/GramD1 proteins were required for plasma membrane(PM)cholesterol to reach the endoplasmic reticulum(ER)in mouse liver during fasting,low-density lipoprotein(LDL)uptake,or reverse cholesterol transport(RCT).The Aster/GramD1 pathway plays a key role in maintaining hepatic and systemic cholesterol/lipid *** is an essential constituent of organellar membranes in mammalian cells[1].

关键词： cholesterol homeostasis hepatic

Roles of exosomes in diagnosis and treatment of colorectal cancer

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World Journal of Clinical Cases 2021年第18期9卷 4467-4479页

作者： yvette Umwali Cong-Bo Yue Abakundana Nsenga Ariston Gabriel Yi Zhang Xin Zhang Department of Clinical Laboratory Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina Department of Clinical Laboratory The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina

Exosomes are extracellular vesicles that mediate intercellular *** contain different molecules,such as DNA,RNA,lipid,and protein,playing essential roles in the pathogenesis of colorectal cancer(CRC).Exosomes derived from CRC are implicated in tumorigenesis,chemotherapy resistance,and ***,they can enhance CRC progression by increasing tumor cell proliferation,reducing apoptosis mechanistically through altering particular essential regulatory genes,or controlling several signaling ***,exosomes derived from CRC are essential biomarkers and can be used in the ***,it is crucial to understand the role of exosomes in CRC,which is necessary to develop diagnostic and therapeutic strategies for early detection and *** the present review,we discuss the roles of exosomes in the diagnosis and treatment of CRC.

关键词： Colorectal cancer Exosomes Biomarker Extracellular vesicle Diagnosis

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Cruising in Hawaii

空中英语教室（高级版．彭蒙惠英语） 2012年第5期 31-34,46,47页

作者： yvette Cardozo