Detection of pancreatic cancer by indocyanine green-assisted fluorescence imaging in the first and second near-infrared windows

作     者：Zhongqiang Li Zheng Li Alexandra Ramos J.Philip Boudreaux Ramcharan Thiagarajan Yvette Bren Mattison Michael E.Dunham Andrew J McWhorter Qing Chen Jian Zhang Ji-Ming Feng Yanping Li Shaomian Yao Jian Xu 

作者机构：Division of Electrical and Computer EngineeringCollege of EngineeringLouisiana State UniversityBaton RougeLA 70803USA Department of Comparative Biomedical ScienceSchool of Veterinary MedicineLouisiana State UniversityBaton RougeLA 70803USA Department of SurgerySchool of MedicineLouisiana State University Health Science CenterNew OrleansLA 70112USA Department of OtolaryngologySchool of MedicineLouisiana State University Health Science CenterNew OrleansLA 70112USA Division of Computer Science&EngineeringCollege of EngineeringLouisiana State UniversityBaton RougeLA 70803USA School of Environment and SustainabilityUniversity of SaskatchewanSaskatoonSK S7N 5C9Canada 

出 版 物：《Cancer Communications》 (癌症通讯（英文）)

年 卷 期：2021年第41卷第12期

页      面：1431-1434页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：This research was supported by Louisiana State University Economic Development Assistantships(000398) LSU Leveraging Innovation for Technology Transfer(LIFT2)Grant(LSU-2021-LIFT-009,LSU-2020-LIFT-008) Health Sciences Center New Orleans,Louisiana State University Grant(HSCNO-2019-LIFT-004) Louisiana Board of Regents Grant(LEQSF(2018-21)-RD-A-09,LEQSF(2020-21)-RD-D-02) NIH(1U01AA029348-01) NSF CAREER award(2046929) 

主　　题：diagnosis specificity neither 

摘      要：Dear Editor,In the United States,pancreatic cancer is considered the fourth most common reason for cancer-related deaths;over 53%of patients are diagnosed at end-stage with a 5-year survival rate of less than 3%[1].Incomplete removal of all cancerous cells generally leads to local recurrence of pancreatic cancer[2].Thus,the detection of tumor margin status plays an essential role in the complete resection of pancreatic *** of the existing imaging modalities,like computed tomography and magnetic resonance imaging,are primarily used for preoperative planning;these modalities also have issues of bulky equipment,radiation concerns,and slow imaging speed[2].Thus,these modalities can neither provide an intraoperative diagnosis of cancer with high sensitivity and specificity nor be used to define tumor margins[3].