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The importance of increasing primary vaccinations against COVID-19 in Europe

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Infectious Disease Modelling 2024年第1期9卷 1-9页

作者： Pierre-yves Boelle Eugenio Valdano sorbonne Universite INSERMInstitut Pierre Louis d’Epidemiologie et de Sante PubliqueF75012ParisFrance

In the European Union,mass vaccination against COVID-19 staved off the strict restrictions that had characterized early epidemic ***,vaccination campaigns are focusing on booster doses,and primary vaccinations have all but ***,52 million European adults are *** investigated if reaching the still unvaccinated population in future vaccination campaigns would substantially decrease the current burden of COVID-19,which is *** focused on vaccination homophily,whereby those who are unvaccinated are mostly in contact with other unvaccinated,making COVID-19 circulation *** quantified vaccination homophily and estimated its impact on COVID-19 *** used an online survey of 1,055,286 people from 22 European countries during early *** computed vaccination homophily as the association between reported vaccination status and perceived vaccination uptake among one's own social contacts,using a case-referent design and a hierarchical logistic *** used this information in an analysis of the COVID-19 reproduction ratio to determine the impact of vaccine homophily in *** homophily was present and strong everywhere:the average odds ratio of being vaccinated for a 10-percentage-point increase in coverage among contacts was 1.66(95%CI=(1.60,1.72)).Homophily was positively associated with the strictness of COVID-19-related restrictions in 2020(Pearson=0.49,P=.03).In the countries studied,12%-to-18%of the reproduction ratio would be attributable to vaccine *** vaccination homophily may curb the reproduction ratio substantially even to the point of preventing recurrent epidemic *** addition to boosting those already vaccinated,increasing primary vaccination should remain a high priority in future vaccination campaigns,to reduce vaccination homophily:this combined strategy may decrease COVID-19 burden.

关键词： COVID-19 Vaccination campaign Reproduction ratio Vaccination homophily survey Europe

Multifunctional properties of a polar spin chain compound[N(C_(3)H_(7))_(4)][Cu(C_(8)H_(4)NO_(4))]·H_(2)O exhibiting both one-dimensional magnetism and nonlinear optical activity

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Chinese Chemical Letters 2024年第2期35卷 622-625页

作者： Ang Li Yanhong Wang Haotian Tian Alimujiang Yalikun yves Journaux Min Luo Hongcheng Lu Key Laboratory of Material Chemistry for Energy Conversion and storage School of Chemistry and Chemical EngineeringHubei Key Laboratory of Bioinorganic Chemistry & Materia MedicaHuazhong University of Science and TechnologyWuhan 430074China Key Laboratory of optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 35002China Institut Parisien de Chimie Moléculaire IPCMSorbonne UniversitéCNRSParis F-75252France

Functional materials with multiple properties are urgent to be explored to reach high requirements for applications *** this work,a new multifunctional one-dimensional(1D)chain compound[N(C_(3)H_(7))_(4)][Cu(ohpma)]·H_(2)O 1(ohpma=deprotonated N-(2-hydoxyphenyl)oxamic acid)exhibiting both 1D antiferromagnetic and nonlinear optical properties,which are both originated from the same polar[Cu(C_(8)H_(4)NO_(4))]magnetic units,has been successfully synthesized by evaporation at room ***-polydentate nature of the(ohpma)3−ligand with constrained tridentate and bidentate coordination sites conducts Cu^(2+)ions coordinating in different geometries and forms 1D chains along the c axis,which are further separated by the[N(C_(3)H_(7))_(4)]+*** the 1D magnetic chains further exhibit noncentrosymmetric polar *** optical study shows polar compound 1 exhibits a discernible second-harmonic generation(sHG)efficiency and the calculation of the partial density of states indicates that the sHG efficiency of 1 is mainly originated from the polar[Cu(C_(8)H_(4)NO_(4))]magnetic ***,magnetic susceptibility shows a broad maximum around 70 K with strong intrachain interaction of J/k B=−113.0 K but no long-range order is observed down to 2 K,suggesting that 1 shows a good 1D *** good 1D magnetism and sHG activity suggest that 1 could be as a potential multifunctional material,particularly.

关键词： Multifunctional properties Magnetic property Nonlinear optical property Evaporation One-dimensional chain

France-China‘Brotherhood'in My Eyes

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China News Release 2024年第2期 14-17页

作者： yves Mouillet tbe French Chaunel of CGTN China Media Group

Though thousands of miles apart,the ancient and refined civilization of China has always held a profound fascination for the people of *** back at the history of recent several centuries,from historical texts and landmarks to meetings between heads of state,we can see many precious moments of amicable exchanges between the two countries.

关键词： refined exchanges profound

Potential of guar gum as a leaky gut model in broilers: Digestibility,performance, and microbiota responses

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Animal Nutrition 2024年第2期17卷 177-187页

作者： Amine Mellouk Tahir Mahmood Maamer Jlali Nuria Vieco-saiz Virginie Michel Pierre Cozannet sarper Ozbek yves Mercier Estelle Devillard Jessika Consuegra Department of R&I in Monogastric Animal Nutrition European Laboratory of Innovation Science & Expertise (ELISE)

Diet is a major modulator of animal resilience and its three pillars: host?s immune response, gut microbiota, and intestinal barrier. In the present study, we endeavour to delineate a challenging condition aimed to degrade these pillars and elucidate its impact on broiler performance and nutrient digestibility. To attain this objective, we opted to use guar gum(GG) as a source of galactomannan. A series of three in vivo experiments were conducted employing conventional or semi-purified diets, supplemented with or without GG during the grower phase(14-28 d). Our findings demonstrate a substantial decline in animal performance metrics such as body weight(reduced by 29%, P sed by 12%, P sion ratio(up to 58% increase, P sence of GG at 2%. The supplementation of a semi-purified diet with incremental doses of GG resulted in a linear reduction(P stibility of dry matter and apparent metabolisable energy. Additionally, a marked reduction in ileal endogenous losses, as well as apparent and standardised digestibility of all amino acids with varying proportions(P s observed. These alterations were accompanied by disrupted gut integrity assessed by fluorescein isothiocyanate-dextran(FITC-d)(P s well as an inflammatory status characterised by elevated levels of acute-phase proteins,namely orosomucoid and serum amyloid A in the sera(P = 0.03), and increased m RNA expression levels of IL-1, IL-6, IL-8, Inos, and K203 genes in the ileum, along with a decrease in Ig A levels in the gut lumen(P sed by reduced diversity and richness(shannon index, P = 0.005) in the presence of GG. Consequently, our results revealed diminished levels of shortchain fatty acids(P = 0.01) and their producer genera, such as Clostridium＿XIVa and Blautia, in the gut caeca, coupled with excessive accumulation of lactate(17-f

关键词： Animal resilience Guar gum Broilers' gut health Performance Digestibility Microbiota

surface movement above old coal longwalls after mine closure

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International Journal of Mining science and Technology 2017年第3期27卷 481-490页

作者： andré Vervoort Pierre-yves Declercq Department of Civil Engineering KU Leuven Leuven 3001 Belgium Geological survey of Belgium Royal Belgian Institute of Natural Sciences Brussels 1000 Belgium

Although most subsidence occurs in the months and years after mining by the longwall method, surface movement is still occurring many decades after the mining. The aim of the study is to quantify the long term behavior. satellite data(radar-interferometry) were analyzed to study an area of about 2 km^2 during the 18 years following the closure of the underground infrastructure and the flooding of the underground workings and rock mass. It was observed that, on average, a residual downward movement took place till 7–12 years after the closure, followed by a clear uplift. However, the first signs of an uplift occurred in certain sub-areas 3–4 years after the closure. Zones within the area studied were identified with either larger or smaller movements. However, the spatial variation of the surface subsidence or uplift could not be directly explained by the characteristics of mining.

关键词： Coal mining surface movement subsidence Uplift Radar-interferometry

Upward surface movement above deep coal mines after closure and flooding of underground workings

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International Journal of Mining science and Technology 2018年第1期28卷 53-59页

作者： andré Vervoort Pierre-yves Declercq Department of Civil Engineering KU Leuven Geological survey of Belgium Royal Belgian Institute of Natural Sciences

After the mass closures of entire coal mine districts in Europe at the end of the last century, a new phenomenon of surface movement was observed—an upward *** most surface movement(i.e., subsidence) occurs in the months and years after mining by the longwall method, surface movement still occurs many decades after mining is *** the closure and flooding of underground excavations and surrounding rock, this movement was *** paper focuses on quantifying the upward movement in two neighboring coal mines(Winterslag and Zwartberg, Belgium).The study is based on data from a remote sensing technique: interferometry with synthetic aperture radar(INsAR).The results of the study show that the rate of upward movement in the decade after closure is about 10 mm/year on *** upward movements are not linked directly to the past exploitation directly underneath a *** amounts of subsidence at specific locations are linked mainly to their positions relative to an inverse trough shape situated over the entire mined-out areas and their immediate *** features, such as geological faults, can have a secondary effect on the local variation of the *** processes of subsidence and uplift are based on completely different *** is initiated by a caving process, while the process of uplift is clearly linked to flooding.

关键词： Coal mining surface movement subsidence Uplift Radar-interferometry

Associations between physical activity levels and ATPase inhibitory factor 1 concentrations in older adults

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Journal of sport and Health science 2024年第3期13卷 409-418页

作者： Jérémy Raffin yves Rolland Annelise Genoux Guillaume Combes Mikael Croyal Bertrand Perret sophie Guyonnet Bruno Vellas Laurent O.Martinez Philipe de souto Barreto For the MAPT/DsA Group Institut du Vieillissement Gérontopôle de ToulouseCentre Hospitalo-Universitaire de ToulouseToulouse 31000France Centre d'Epidémiologie et de Recherche en santédes Populations UnitéMixte de Recherche 1295Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse-III-Paul-SabatierToulouse 31000France LimitAging Team Institut des Maladies Métaboliques et CardiovasculairesUnitéMixte de Recherche 1297Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse III-Paul SabatierToulouse 31432France service de Biochimie Pôle de biologieHôpital de PurpanCentre Hospitalo-Universitaire de ToulouseToulouse 31300France L'Institut du Thorax Institut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France BioCore US16Structure Fédérative de Recherche BonamyInstitut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France Plate-forme de spectrométrie de masse Centre de Recherche en Nutrition HumaineOuestNantes 44000France 不详

Background:Adenosine triphosphatase inhibitory factor 1(IF1)is a key protein involved in energy ***1 has been linked to various agerelated diseases,although its relationship with physical activity(PA)remains ***,the apolipoprotein A-I(apoA-I),a PA-modulated lipoprotein,could play a role in this relationship because it shares a binding site with IF1 on the cell-surface ATP *** examined here the associations between chronic PA and plasma IF1 concentrations among older adults,and we investigated whether apoA-I mediated these ***:In the present work,1096 healthy adults(63.8%females)aged 70 years and over who were involved in the Multidomain Alzheimer Prevention Trial study were ***1 plasma concentrations(square root of ng/mL)were measured at the 1-year visit of the Multidomain Alzheimer Prevention Trial,while PA levels(square root of metabolic equivalent task min/week)were assessed using questionnaires administered each year from baseline to the 3-year *** linear regressions were performed to investigate the associations between the first-year mean PA levels and IF1 *** analyses were conducted to examine whether apoA-I mediated these *** linear regressions were carried out to investigate whether the 1-year visit IF1 concentrations predicted subsequent changes in ***:Multiple linear regressions indicated that first-year mean PA levels were positively associated with IF1 concentrations(B=0.021;sE=0.010;p=0.043).Mediation analyses revealed that about 37.7%of this relationship was mediated by apoA-I(B_(ab)=0.008;sE=0.004;p=0.023).Longitudinal investigations demonstrated that higher concentrations of IF1 at the 1-year visit predicted a faster decline in PA levels over the subsequent 2 years(time×IF1:B=0.148;sE=0.066;p=0.025).Conclusion:This study demonstrates that regular PA is associated with plasma IF1 concentrations,and it suggests that apoA-I partly med

关键词： Aging Apolipoprotein Bioenergetics Exerkine Mitochondria

François Noel,Reading Chinese Philosophy and spiritual Transformation

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国际儒学（中英文） 2024年第2期4卷 150-169,193,194页

作者：温德法国天主教里尔大学巴黎59016

卫方济(1651—1729)1711年出版了两本与中国哲学有关的书。《中国哲学》根据亚里士多德的框架向欧洲人介绍儒家思想,《中国经典》是六部儒家经典的译本。这两本书论述了一位欧洲传教士是如何通过阅读儒家经典及其注释而得到转变的。尽... 详细信息

卫方济(1651—1729)1711年出版了两本与中国哲学有关的书。《中国哲学》根据亚里士多德的框架向欧洲人介绍儒家思想,《中国经典》是六部儒家经典的译本。这两本书论述了一位欧洲传教士是如何通过阅读儒家经典及其注释而得到转变的。尽管卫方济的著作被卷入“中国礼仪之争”,克里斯蒂安·沃尔夫等几位德国哲学家对这些著作还是有所了解的,并在伦理领域的理性自主性受到威胁的辩论中使用了这些著作。卫方济的理论前提和解释方法可能从当代学术的角度看已经不再那么重要,但是他的这一案例表明,儒家经典的阅读是可以在伦理与实践的层面上改变一个欧洲学者的。卫方济的作品也邀请我们重新考虑系统哲学和作为实践的哲学之间的现代分裂,而这一分裂皮埃尔·哈多的著作已经做以批评了。从这个意义上说,卫方济将亚里士多德与孔子联系起来的尝试见证了一场更大的运动。

关键词： François Noël 新儒家比较哲学

Numerical Assessment of the Thermal Efficiency of a Concentrated Photovoltaic/Thermal (CPV/T) Hybrid system Using Air as Heat Transfer Fluid

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smart Grid and Renewable Energy 2024年第1期15卷 1-14页

作者： Amadou Konfe Boureima Kabore yves Christian Nonguierma Fatimata Ouedraogo sié Kam Laboratory of Thermal and Renewable Energies University Joseph Ki-Zerbo Ouagadougou Burkina Faso Physic Department University Norbert Zongo Koudougou Burkina Faso Photonics and Nolinear Optics Laboratory University of Moncton Moncton Canada

In this paper, we propose a thermal model of a hybrid photovoltaic/thermal concentration system. starting from the thermal balance of the model, the equation is solved and simulated with a MATLAB code, considering air as the cooling fluid. This enabled us to evaluate some of the parameters influencing the electrical and thermal performance of this device. The results showed that the temperature, thermal efficiency and electrical efficiency delivered depend on the air mass flow rate. The electrical and thermal efficiencies for different values of air mass flow are encouraging, and demonstrate the benefits of cooling photovoltaic cells. The results show that thermal efficiency decreases air flow rate greater than 0.7 kg/s, whatever the value of the light concentration used. The thermal efficiency of the solar cell increases as the light concentration increases, whatever the air flow rate used. For a concentration equal to 30 sun, the thermal efficiency is 0.16 with an air flow rate equal to 0.005 kg/s;the thermal efficiency increases to 0.19 with an air flow rate equal to 0.1 kg/s at the same concentration. An interesting and useful finding was that the proposed numerical model allows the determination of the electrical as well as thermal efficiency of the hybrid CPV/T with air flow as cooling fluid.

关键词： PV Cell Concentrating Thermal Energy Conversion Cooling Hybrid system