检索结果-南通市图书馆

Starch-based adhesive hydrogel with gel-point viscoelastic behavior and its application in wound sealing and hemostasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第4期63卷 228-235页

作者： yuxuan mao Peng Li Jiewei Yin Yanjie Bai Huan Zhou Xiao Lin Huilin Yang Lei Yang College of Chemistry Chemical Engineering and Materials ScienceOrthopaedic InstituteSoochow UniversitySuzhou215000China Department of Orthopaedics The First Affiliated HospitalSoochow UniversitySuzhou215000China School of Public Health Soochow UniversitySuzhou215000China Center for Health Science and Engineering(CHSE) School of Materials Science and EngineeringHebei University of TechnologyTianjin300000China School of Mechanical Engineering Jiangsu University of TechnologyChangzhou213000China

Hydrogels with tissue adhesiveness have demonstrated great promise for wearable electronics,artificial skin,soft robotics,and tissue ***,adhesive hydrogels that are capable of sealing and hemostasis of wound with severe hemorrhage still *** this purpose,a series of ionically crosslinked starch hydrogels were developed *** viscoelastic properties and tissue adhesiveness of the starch hydrogels were *** is shown that the starch and cross linkers had significant influence on the viscoelastic properties of the starch hydrogels,which further resulted in varied tissue *** the starch gels,there was one exhibiting a unique and stable"Gel Point"viscoelastic characteristic and it was named as gel-point adhesive hydrogel(GPAH).GPAH showed electrical conductivity,high tissue adhesiveness,high stretch-ability,self-healing capability,injectability,and *** GPAH also exhibited high cytocompatibility,low hemolysis risk,and strong antibacterial *** wound sealing and hemostatic performance of GPAH was further evaluated by a rat femoral artery injury *** blood loss after the sealing of GPAH(2.4±1.3 g)was significantly decreased compared to the group using gauze for sealing(6.3±1.5 g).Meanwhile,GPAH did not cause pathological changes of the soft tissues surrounding the *** above results indicate that GPAH,with high tissue adhesiveness,suitable viscoelastic property,strong antibacterial capacity,as well as electro-conductivity,bears great potential for the applications in smart wound management.

关键词： sealing viscoelastic hydrogel

Characteristics of novel Ti-10Mo-xCu alloy by powder metallurgy for potential biomedical implant applications

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2020年第3期5卷 659-666页

作者： Wei Xu Chenjin Hou yuxuan mao Lei Yang Maryam Tamaddon Jianliang Zhang Xuanhui Qu Chaozong Liu Bo Su Xin Lu Beijing Advanced Innovation Center for Materials Genome Engineering State Key Laboratory for Advanced Metals and MaterialsInstitute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijingChina Institute of Orthopaedic&Musculoskeletal Science University College LondonRoyal National Orthopaedic HospitalStanmoreHA74LPUK Center for Health Science and Engineering Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control TechnologySchool of Materials Science and EngineeringHebei University of TechnologyTianjin300130China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China Bristol Dental School University of BristolBristolBS12LYUK

When biomaterials are implanted in the human body,the surfaces of the implants become favorable sites for microbial adhesion and biofilm formation,causing peri-implant infection which frequently results in the failure of prosthetics and revision ***-Mo alloy is one of the commonly used implant materials for load-bearing bone replacement,and the prevention of infection of Ti-Mo implants is therefore *** this study,bacterial inhibitory copper(Cu)was added to Ti-Mo matrix to develop a novel Ti-Mo-Cu alloy with bacterial inhibitory *** effects of Cu content on microstructure,tensile properties,cytocompatibility,and bacterial inhibitory ability of Ti-Mo-Cu alloy were systematically *** revealed that Ti-10Mo-1Cu alloy consisted ofαandβphases,while there were a few Ti2Cu intermetallic compounds existed for Ti-10Mo-3Cu and Ti-10Mo-5Cu alloys,in addition toαandβ*** tensile strength of Ti-10Mo-xCu alloy increased with Cu content while elongation ***-10Mo-3Cu alloy exhibited an optimal tensile strength of 1098.1 MPa and elongation of 5.2%.Cytocompatibility study indicated that none of the Ti-10Mo-xCu alloys had a negative effect on MC3T3-E1 cell *** inhibitory rates against *** and *** increased with the increase in Cu content of Ti-10Mo-xCu alloy,within the ranges of 20-60%and 15-50%,*** together,this study suggests that Ti-10Mo-3Cu alloy with high strength,acceptable elongation,excellent cytocompatibility,and the bacterial inhibitory property is a promising candidate for biomedical implant applications.

关键词： Ti-10Mo-xCu alloy Microstructure Mechanical properties Cytocompatibility Bacterial inhibitory property

Portal Fibrotic Cord is Associated with Transjugular Intrahepatic Portosystemic Shunt Failure and Death in Cirrhotic Patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2023年第4期11卷 809-816页

作者： Yunshu Yang Chuangye He Xulong Yuan Kai Li Wenyuan Jia Jing Niu Na Han Jiao Xu Ying Zhu Li Xu yuxuan mao Yuanping Xu Xiaoyuan Gou Jun Tie National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases Air Force Medical UniversityXi’anShaanxiChina

Background and Aims:Occlusive portal vein thrombosis(PVT)often causes portal hypertension-related complications in cirrhotic *** intrahepatic portosystemic shunt(TIPS)is an effective treatment for this difficult ***,the factors influencing TIPS success and overall survival in patients with occlusive PVT are *** study investigated the factors influencing TIPS success and overall survival in cirrhotic patients with occlusive ***:Cirrhotic patients with occlusive PVT were selected from a prospective database of consecutive patients treated with TIPS in Xijing Hospital between January 2015 and May *** characteristics,TIPS success rate,complications,and survival were collected,and the factors associated with the TIPS success rate and transplant-free survival were ***:A total of 155 cirrhotic patients with occlusive PVT were *** succeeded in 126(81.29%)*** 1-year survival rate was 74%.Compared with those without,patients with portal fibrotic cord had a lower TIPS success rate(39.02%vs.96.49%,p<0.001),shorter median overall survival(300 vs.1,730 days,p<0.001)and more operation-related complications(12.20%vs.1.75%,p<0.01).Logistic regression analysis found that portal fibrotic cord(odds ratio 0.024)was a risk factor for TIPS *** and multivariate analysis showed that portal fibrotic cord was an independent predictor of death(hazard ratio 2.111;95%CI:1.094-4.071,p=0.026).Conclusions:Portal fibrotic cord increased the TIPS failure rate and is a risk factor for poor prognosis in cirrhotic patients.

关键词： Fibrotic cord Occlusive portal vein thrombosis Portal hypertension-related complications Transjugular intrahepatic portosystemic shunt Liver cirrhosis

Physical dosimetric reconstruction of a case of large area back skin injury due to overexposure in an interventional procedure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Radiation Medicine and Protection 2022年第1期3卷 3-8页

作者： Yuchen Yin Xuan Wang Xianghui Kong Wenyue Zhang Yidi Wang yuxuan mao Jianwei Wang Tianhe Jia Yu Tu Bingjie Zhang Liang Sun State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and ProtectionSoochow UniversityCollaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education InstitutionsSuzhou 215123China Prevention and Treatment Center for Occupational Disease of Xinxiang City XinxiangHenan 453003China

To estimate the physical dose of skin and key organs in a case of overexposure during a cardiac interventional *** The female patient aged 50 suffered from owerexposure during ardiac interventional therapy in a hospital,Xinxiang city,Henan province,China in January *** mesh-type phantom for the patient was constructed based on the adult mesh-type reference computational phantoms(MRCPs)released by the International Comission on Radiological Protection Publication 145 (ICRP145)and phantom deformation *** of exposure scenario were constructed and simulated with particle and heavy ion transport code system(PHTTS)according to exposure ***:The maximum absorbed dose of key organs/tissues under iradiation in posteroanterior(PA)and 30°left anterior oblique directions(LOA)was 632.4 and 305.6 mGy,*** let lung,heart,and left mammary gland received a larger dose under both iradiation *** ratio of the absorbed dose with and without shielding was a lculated,and the relative difference in most organs was<1%between two *** iso-dose curve of the back skin revealed the ditribution of the absorbed dose(0.1-5.2 Gy).The dose estimate of key tssues/organs was higher than the conventional level,especially the local skin,up to 5.2 *** The interventional procedure in this ase resulted in a higher *** Carlo codes combined with the MRCPs can be employed to estimate physical dose to individuals in concrete irradia tion scenarios.

关键词： Physical dose Dose reconstruction Digital subtraction angiography Monte Carlo codes Particle and heavy ion transport code system (PHITS) Mesh-type phantoms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

军校本科生心理危机预警关键指标的构建

中国健康心理学杂志 2023年第12期31卷 1870-1875页

作者：茅瑜璇韩立敏刘星中国人民解放军国防科技大学湖南长沙410008 天津警备区河东第一离职干部休养所

目的:探索用于军校本科生心理危机预警的关键指标,在个体发生严重恶劣危机事件之前对其进行识别干预,做到防患于未然。方法:采用开放式问卷调查、德尔菲法构建军校本科生心理危机预警的指标条目。以处理过本科生严重心理危机事件的学员... 详细信息

目的:探索用于军校本科生心理危机预警的关键指标,在个体发生严重恶劣危机事件之前对其进行识别干预,做到防患于未然。方法:采用开放式问卷调查、德尔菲法构建军校本科生心理危机预警的指标条目。以处理过本科生严重心理危机事件的学员队干部为研究对象,采用自编开放式问卷提取军校本科生心理危机预警初始指标,而后采用德尔菲法对获得的初步指标进行专家咨询,经4轮咨询后取得心理危机关键预警指标。结果:开放式问卷调查得到42条初始预警指标;4轮德尔菲法专家积极系数均为100%,权威程度分别为0.859,0.886,0.863,0.859,Kendall’s W分别为0.325,0.174,0.118,0.095,P<0.05,重要性赋值均值分别为3.897、4.044、4.208、4.252,最终形成应激源、应激反应、易感因素3个维度共11项重要预警指标。结论:专家积极性、权威程度、意见集中程度较高,构建的军校本科生心理危机关键预警指标科学、合理。

关键词：心理危机心理危机预警预警指标德尔菲法

在线全文

学校读者我要写书评

暂无评论

胰颈炎性肌纤维母细胞瘤1例

中华肝胆外科杂志 2023年第5期29卷 383-384页

作者：马嘉骏毛宇轩李云峰刘宇田秉璋湖南师范大学附属第一医院(湖南省人民医院)肝胆外科长沙410005 湖南师范大学附属第一医院(湖南省人民医院)病理科长沙410005

胰腺炎性肌纤维母细胞瘤是罕见的胰腺原发肿瘤,原发于胰腺颈部者更为罕见。胰腺炎性肌纤维母细胞瘤临床表现不典型,影像学检查无特征性变化,术前诊断困难,极易误诊。本文报道1例湖南师范大学附属第一医院(湖南省人民医院)收治的胰颈炎... 详细信息

胰腺炎性肌纤维母细胞瘤是罕见的胰腺原发肿瘤,原发于胰腺颈部者更为罕见。胰腺炎性肌纤维母细胞瘤临床表现不典型,影像学检查无特征性变化,术前诊断困难,极易误诊。本文报道1例湖南师范大学附属第一医院(湖南省人民医院)收治的胰颈炎性肌纤维母细胞瘤患者行腹腔镜下胰腺中段切除术,术后病理为炎性肌纤维母细胞性肿瘤,以期为临床医师诊治胰腺炎性肌纤维母细胞瘤提供一定参考。

关键词：炎性肌纤维母细胞瘤湖南省人民医院医师诊治胰腺中段切除术原发肿瘤影像学检查术前诊断胰颈

基于络病理论探讨皮肤针治疗带状疱疹后神经痛

在线全文

学校读者我要写书评

暂无评论

四川中医 2023年第2期41卷 28-32页

作者：毛玉璇潘世杰常甜王艳君河北中医学院第一附属医院河北石家庄050011 河北省中医院河北石家庄050011

带状疱疹后神经痛是一种常见的神经病理性疼痛,临床表现为发疹部位疼痛不适,可严重影响患者生活质量。中医外治法治疗带状疱疹后神经痛安全有效,其中皮肤针因具有操作简便、刺激强度灵活等特点,广泛应用于临床。络病理论源于《黄帝内经... 详细信息

带状疱疹后神经痛是一种常见的神经病理性疼痛,临床表现为发疹部位疼痛不适,可严重影响患者生活质量。中医外治法治疗带状疱疹后神经痛安全有效,其中皮肤针因具有操作简便、刺激强度灵活等特点,广泛应用于临床。络病理论源于《黄帝内经》,多用于慢性病的临床诊治,与带状疱疹后神经痛的发病及诊疗密切相关。故本文基于络病理论探讨带状疱疹后神经痛的病因病机及皮肤针治疗,认为络脉痹阻与络脉虚滞为其主要病机,治疗以通络为原则,通过祛邪通络、扶正通络恢复络脉正常的生理功能,进一步为皮肤针治疗带状疱疹后神经痛提供临床依据。

关键词：带状疱疹后神经痛络病理论皮肤针通络综述

不同工种放射工作人员外周血淋巴细胞染色体畸变分析

在线全文

学校读者我要写书评

暂无评论

中华放射医学与防护杂志 2016年第9期36卷 659-661页

作者：刘纪青毛喻萱王轩霍海伟刘彤桢张冰洁河南省新乡市职业病防治研究所新乡453003

放射工作人员因长期低剂量电离辐射可以引起神经系统、造血系统、眼品状体、视神经、性腺和免疫系统等方面的生物效应改变，也会导致遗传物质损伤．甚至有引发恶性肿瘤的风险。为进一步了解低剂量电离辐射对放射工作人员的辐射损伤情况... 详细信息

放射工作人员因长期低剂量电离辐射可以引起神经系统、造血系统、眼品状体、视神经、性腺和免疫系统等方面的生物效应改变，也会导致遗传物质损伤．甚至有引发恶性肿瘤的风险。为进一步了解低剂量电离辐射对放射工作人员的辐射损伤情况，对接诊的508名放射工作人员染色体畸变进行分析。

关键词：放射工作人员染色体畸变分析外周血淋巴细胞低剂量电离辐射工种遗传物质损伤神经系统造血系统

在线全文

学校读者我要写书评

暂无评论

城市放射性废物库区域γ剂量监测系统的设计

核电子学与探测技术 2023年第5期43卷 1014-1020页

作者：唐辉谷洪刘佩徐彬赵强李元东何岱毛昱璇四川省辐射环境管理监测中心站成都611139

为满足城市放射性废物库γ剂量监测的需求,设计了区域γ剂量监测系统。该系统设计了γ探测器、就地声光报警器、数据采集主机、管理软件等模块,采用有线和无线网络对各模块进行链接和整合,实现了对库房的全域实时监控,并将剂量监控报警... 详细信息

为满足城市放射性废物库γ剂量监测的需求,设计了区域γ剂量监测系统。该系统设计了γ探测器、就地声光报警器、数据采集主机、管理软件等模块,采用有线和无线网络对各模块进行链接和整合,实现了对库房的全域实时监控,并将剂量监控报警与库区其他安防设施实现了连锁管理;强化了城市放射性废物库的辐射监测能力和安防能力,提高库区的管理水平和辐射事故应急处置能力,可为其他城市放射性废物库剂量监测系统的设计提供技术支持和参考。

关键词：城市放射性废物库 γ剂量区域测量