Injectable hydrogel wound dressing based on strontium ion cross-linked starch

作     者：Yuxuan MAO Mingming PAN Huilin YANG Xiao LIN Lei YANG Yuxuan MAO;Mingming PAN;Huilin YANG;Xiao LIN;Lei YANG

作者机构：College of ChemistryChemical Engineering and Materials ScienceOrthopaedic InstituteSoochow UniversitySuzhou 215006China Department of OrthopaedicsThe First ffiliated HospitalSoochow UniversitySuzhou 215006China Center for Health Science and EngineeringSchool of Materials Science and EngineeringHebei University of TechnologyTianjin 300131China 

出 版 物：《Frontiers of Materials Science》 (材料学前沿（英文版）)

年 卷 期：2020年第14卷第2期

页      面：232-241页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 0836[工学-生物工程] 

基　　金：sponsored by the National Natural Science Foundation of China(Grant Nos.51672184,81930070,81622032 and 81501858) the Natural Science Research of Jiangsu Higher Education Institutions(No.17KJA180011) the Jiangsu Innovation and Entrepreneur-ship Program,and the Priority Academice Program Development of Jiangsu High Education Institutions(PAPD) 

主　　题：wound dressing injectable antibacterial gel-point adhesive hydrogel(GPAH) 

摘      要：Severe skin wounds cause great problems and sufferings to *** this study,an injectable wound dressing based on strontium ion cross-linked starch hydrogel(SSH)was developed and *** good inject-ability of SSH made it easy to be delivered onto the wound *** good tissue adhesiveness of SSH ensured a firm protection of the ***,SSH supported the proliferation of NIH/3T3 fibroblasts and facilitated the migration of human umbilical vein endothelial cells(HUVECs).Importantly,SSH exhibited strong antibacterial effects on Staphylococcus aiireiis(***/rec/s),which could prevent wound *** results demonstrate that SSH is a promising wound dressing material for promoting wound healing.