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An overview of potential cardioprotective benefits of xanthophylls in atherosclerosis:an evidence-based review

Food Science and Human Wellness 2024年第4期13卷 1739-1755页

作者： yuting su Feng Chen Jiehua Chen Mingfu Wang Shenzhen Key Laboratory of Marine Microbiome Engineering Institute for Advanced StudyShenzhen UniversityShenzhen 518060China Institution for Innovative Development of Food Industry Shenzhen UniversityShenzhen 518060China College of Civil and Transportation Engineering Shenzhen UniversityShenzhen 518060China Shenzhen Key Laboratory of Food Nutrition and Health Shenzhen UniversityShenzhen 518060China

Atherosclerosis,as the most prevalent form of cardiovascular disease,is characterized by oxidized lowdensity lipoprotein(ox-LDL)accumulation in the vascular wall,increased inflammation of the large arteries,dysfunction of the endothelial cells(ECs)and vascular smooth muscle cells(VSMCs),which may eventually lead to the formation of ***,one of the main groups of carotenoids,have been proposed as preventive agents or adjunct therapies to prevent and slow the progression of atherosclerosis due to their cardioprotective ***,the underlying preventive mechanism of action of xanthophylls on the pathogenesis of atherosclerosis remains unclear,and clinical evidence of the effect of xanthophylls on atherosclerosis have not yet been summarized and critically *** this regard,we conducted a comprehensive literature search in four scientific databases(Pub Med,Google Scholar,Science Direct and Web of Science)and carefully analyzed the existing evidence to provide meaningful insights on the association between xanthophylls and atherosclerosis from various *** on the evidence from in vitro and in vivo studies,we explored several potential mechanisms,including antioxidant effect,anti-inflammatory effect,regulation of lipid metabolism,and modulation of ECs and VSMCs dysfunction,and we found that a clear picture of regulatory pathways of xanthophylls on atherosclerosis prevention and treatment is still *** addition,epidemiological studies suggested the possible relationship among high dietary intake of xanthophylls,high plasma/serum xanthophylls and a reduced risk of *** evidence from interventional studies investigating the effect of xanthophylls on atherosclerosis is very sparse,whilst indirect clinical evidence was only limited to astaxanthin and ***,well-designed long-term randomized controlled trials(RCTs)are highly recommended for future studies to investigate the effective dose of different

关键词： Atherosclerosis Xanthophylls Antioxidant Anti-inflammation Lipid metabolism

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A multiple copyright identification watermarking algorithm based on code division multiple access

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High Technology Letters 2008年第4期14卷 377-383页

作者：张帆 li Jie su yuting Zhang Chuntian College of-Computer ＆ Information Engineering Henan University Kaifeng 475001 P. R. China College of Electronic ＆ Information Engineering Tianjin University Tianjin 300072 P.R. China

A multiple watermarking algorithm is presented according to the multiple accessing technique of the code division multiple access （CDMA） system. Multiple watermarks are embedded into digital images in the wavelet transform domain. Each of the watermarks is embedded and extracted independently without impacts to each other. Multiple watermarks are convolution encoded and block interleaved, and the orthogonal Gold sequences are used to spread spectrum of the copyright messages. CDMA encoded water-mark messages are embedded into the wavelet sub-bands excluding the wavelet HH1 sub-bands. The embedment amplitude is decided by Watson＇ s perceptual model of wavelet transform domain, and the embedmeut position in the selected wavelet sub-bands is decided randomly by a pseudo-random noise （PN） sequence. As a blind watermm＇king algorithm, watermarks are extracted without original image. The watermarking capacity of proposed algorithm is also discussed. When two watermarks are embedded in an image at the same time, the capacity is larger than the capacity when a single watermark is embedded, and is smaller than the sum of the capacity of two separately embedded watermarks. Experimental results show that the proposed algorithm improves the detection bits error rate （BER） observably, and the multiple watermarks have a preferable robustness and invisibility.

关键词： code division multiple access (CDMA) watermarking convolutional coding

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Multi-modal Correlated Network for emotion recognition in speech

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Visual Informatics 2019年第3期3卷 150-155页

作者： Minjie Ren Weizhi Nie Anan Liu yuting su The School of Electrical and Information Engineering Tianjin UniversityChina

With the growing demand of automatic emotion recognition system,emotion recognition is becoming more and more crucial for human-computer interaction(HCI)***,there is a continuous improvement in the performance of automatic emotion recognition due to the development of both hardware and deep learning ***,because of the abstract concept and multiple expressions of emotion,automatic emotion recognition is still a challenging *** this paper,we propose a novel Multi-modal Correlated Network for emotion recognition aiming at exploiting the information from both audio and visual channels to achieve more robust and accurate *** the proposed method,the audio signals and visual signals are first preprocessed for the feature *** preprocessing,we obtain the Mel-spectrograms,which can be treated as images,and the representative frames from visual *** the Mel-spectrograms are fed to the convolutional neural network(CNN)to get the audio features and the representative frames are fed to the CNN and LSTM to get ***,we employ the triplet loss to increase the differentiation of ***,we propose a novel correlated loss to reduce the differentiation of ***,we apply the feature fusion method to fuse the audio and visual feature for emotion recognition *** experimental result on AEFW dataset demonstrates the correlation information of multiple modals is crucial for automatic emotion recognition and the proposed method can achieve the state-of-the-art performance on the classification task.

关键词： Multi-modal Emotion recognition Neural networks

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Immobilization of heparin on decellularized kidney scaffold to construct microenvironment for antithrombosis and inducing reendothelialization

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Science China(Life Sciences) 2018年第10期61卷 1168-1177页

作者： Miao Wang Lili Bao Xinyu Qiu Xiaoshan Yang Siying Liu yuting su Lulu Wang Bo Liu Qing He Shiyu Liu Yan Jin State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi International Joint Research Center for Oral Diseases Center for Tissue Engineering School of Stomatology Fourth Military Medical UniversityXi'an 710032 China Shaanxi Institute of Medical Device Quality supervision and Inspection Xi'an 721046 China Research and Development Center for Tissue Engineering Fourth Military Medical UniversityXi'an 710032 China Xi'an Institute of Tissue Engineering and Regenerative Medicine Xi'an 710032 China State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases Department of Orthodontics School of Stomatology Fourth Military Medical UniversityXi'an 710032 China Department of aerospace Fourth Military Medical UniversityXi'an 710032 China State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases Department of Pediatric Dentistry School of Stomatology Fourth Military Medical UniversitXi'an 710032 China

In recent years, rapid development of tissue engineering technology provides possibilities for the construction of artificial tissues or organs. In construction of engineered kidneys, researchers used native decellularized extracellular matrix(ECM) as the scaffolds to recellularization. However, thrombosis has been a great issue that hinders the progress of transplantation in vivo. In this study, heparin was immobilized to the collagen part of decellularized scaffold with collagen-binding peptide(CBP). Through the anticoagulant and endothelial cell reperfusion experiments, it can be demonstrated that the heparinized scaffolds absorbed less platelets and red blood cells which can effectively reduce the formation of thrombosis. Moreover, it is conducive to longterm adhesion of endothelial cells which is important for the formation of subsequent vascularization. Taken together, our results reveal that the whole kidney can be modified by CBP-heparin composite to reduce the thrombosis and provide the better conditions for neovascularization.

关键词： decellularization kidney scaffold antithrombosis reendothelialization

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MSCs-derived apoptotic extracellular vesicles promote muscle regeneration by inducing Pannexin 1 channel-dependent creatine release by myoblasts

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International Journal of Oral Science 2023年第1期15卷 63-75页

作者： Qingyuan Ye Xinyu Qiu Jinjin Wang Boya Xu yuting su Chenxi Zheng Linyuan Gui Lu Yu Huijuan Kuang Huan Liu Xiaoning He Zhiwei Ma Qintao Wang Yan Jin State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi International Joint Research Center for Oral Diseases Center for Tissue EngineeringSchool of StomatologyAir Force Medical UniversityXi’anChina State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Key Laboratory of Stomatology Digital Dentistry CenterSchool of StomatologyAir Force Medical UniversityXi’anChina State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Clinical Research Center for Oral Diseases Department of Preventive DentistrySchool of StomatologyAir Force Medical UniversityXi’anChina State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture Department of PeriodontologySchool of StomatologyAir Force Medical UniversityXi’anChina State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Key Laboratory of Oral Diseases Department of ProsthodonticsSchool of StomatologyAir Force Medical UniversityXi’anChina Aerospace Clinical Medical Center School of Aerospace MedicineAir Force Medical UniversityXi’anChina Department of Otolaryngology Head and Neck surgery Peking University Third HospitalBeijingChina

Severe muscle injury is hard to heal and always results in a poor *** studies found that extracellular vesicle-based therapy has promising prospects for regeneration medicine,however,whether extracellular vesicles have therapeutic effects on severe muscle injury is still ***,we extracted apoptotic extracellular vesicles derived from mesenchymal stem cells(MSCs-Apo EVs)to treat cardiotoxin induced tibialis anterior(TA)injury and found that MSCs-Apo EVs promoted muscles regeneration and increased the proportion of multinucleated *** that,we also found that apoptosis was synchronized during myoblasts fusion and MSCs-Apo EVs promoted the apoptosis ratio as well as the fusion index of ***,we revealed that MSCs-Apo EVs increased the relative level of creatine during myoblasts fusion,which was released via activated Pannexin 1 ***,we also found that activated Pannexin 1 channel was highly expressed on the membrane of myoblasts-derived Apo EVs(Myo-Apo EVs)instead of apoptotic myoblasts,and creatine was the pivotal metabolite involved in myoblasts ***,our findings firstly revealed that MSCs-Apo EVs can promote muscle regeneration and elucidated that the new function of Apo EVs as passing inter-cell messages through releasing metabolites from activated Pannexin 1 channel,which will provide new evidence for extracellular vesicles-based therapy as well as improving the understanding of new functions of extracellular vesicles.

关键词： apo extracellular release

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深度多模态不确定度的短视频事件检测方法

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哈尔滨工业大学学报 2024年第5期56卷 36-45页

作者：苏育挺王富铕井佩光天津大学电气自动化与信息工程学院天津300072

随着短视频的快速发展,短视频事件检测任务受到越来越多的关注。现有短视频事件检测研究普遍采用深度神经网络来获得确定的检测结果,但是网络忽略了不确定度的影响从而导致错误的预测结果也会产生过度置信的决策。为了解决上述问题,本... 详细信息

随着短视频的快速发展,短视频事件检测任务受到越来越多的关注。现有短视频事件检测研究普遍采用深度神经网络来获得确定的检测结果,但是网络忽略了不确定度的影响从而导致错误的预测结果也会产生过度置信的决策。为了解决上述问题,本文提出了一个深度多模态不确定度网络的短视频事件检测方法。首先,该方法在传统域分离网络中嵌入变分层,用来获得预测分布;然后,将视觉模态信息和音频模态信息输入到网络中,利用该方法所构建的独立性和相关性损失可以获得包含不确定度的音频模态共、私有域预测分布以及视觉模态共、私有域预测分布;最后,提出了一个不确定度判别法则用来筛选4个域的预测分布,从而得到最终的预测结果。在公开数据集(UCF-101与HMDB51)和新构建的短视频事件检测数据集上进行了实验。实验结果表明,面对不同的深度分类方法以及不同的数据集,本文方法不仅有着更高的分类准确率,还可以对输出结果进行不确定度估计,针对音频的干扰也具有较强的鲁棒性。

关键词：深度神经网络短视频事件检测域分离网络变分层模态不确定度

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图像信息隐藏容量与最小可检测容量分析

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高技术通讯 2008年第11期18卷 1148-1153页

作者：张帆张春田苏育挺天津大学电子信息工程学院天津300072 河南大学计算机与信息工程学院开封475001

在前期研究工作的基础上,提出了一种不同于现有以信息论为基础的图像信息隐藏容量分析方法,该方法基于联想记忆神经网络的吸引子和吸引域理论,研究数字图像的信息可隐藏容量的极限问题,并把信息隐藏容量与最小可检测容量问题——隐藏信... 详细信息

在前期研究工作的基础上,提出了一种不同于现有以信息论为基础的图像信息隐藏容量分析方法,该方法基于联想记忆神经网络的吸引子和吸引域理论,研究数字图像的信息可隐藏容量的极限问题,并把信息隐藏容量与最小可检测容量问题——隐藏信息量的上限和下限问题统一在同一个理论框架之内。研究结果表明,如果隐藏信息后的图像与宿主图像之间的汉明距离超出神经网络吸引域范围,就无法正确地检测出隐藏的信息;神经网络的容量决定了在一定检测错误率情况下最少需要嵌入的信息量;图像中可以隐藏的最大信息量取决于神经网络的吸引域;最小可检测信息量取决于神经网络的吸引子。该方法是对现有基于信息论方法的有益补充。

关键词：信息隐藏容量神经网络

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一种多模态特征编码的短视频多标签分类方法

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西安电子科技大学学报 2022年第4期49卷 109-117页

作者：井佩光李亚鑫苏育挺天津大学电气自动化与信息工程学院天津300072

随着智能手机的普及和移动互联网的发展,短视频作为一种新兴的用户生成内容得到快速传播,浏览短视频也成为了最流行的娱乐方式之一。短视频天然具有模态和语义上的关联性,如何利用这种关联性是短视频表示学习的关键。针对短视频的多标... 详细信息

随着智能手机的普及和移动互联网的发展,短视频作为一种新兴的用户生成内容得到快速传播,浏览短视频也成为了最流行的娱乐方式之一。短视频天然具有模态和语义上的关联性,如何利用这种关联性是短视频表示学习的关键。针对短视频的多标签分类问题,提出了一种基于多模态子空间编码的短视频多标签分类模型,该模型将多模态下的子空间编码学习同标签语义相关性学习整合为一个统一框架。模型利用子空间编码网络获取完备的公共表示,充分挖掘短视频多个模态下的一致性和互补性信息,同时去除冗余信息,减小噪声的影响,获取模态融合的公共完备表示;利用图卷积网络构建标签相关性矩阵,学习标签间语义关联表示,将其用于指导多标签分类任务。对特征层和标签层信息进行更充分的融合交互以提高分类性能。算法从整体上构建了模态重构损失和多标签分类损失,充分利用短视频的多模态特性和多标签关联,在公开数据集上进行实验,证明了所提模型在分类任务的有效性和优越性。

关键词：短视频多模态融合深度学习多标签分类神经网络

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基于频率约束的相机与屏幕通信隐写算法

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激光与光电子学进展 2018年第5期55卷 116-123页

作者：褚晶辉田叶苏育挺天津大学电气自动化与信息工程学院天津300072

移动设备的快速普及,催生了一系列新的信息获取方式,其中,最具代表性的是已广泛应用于移动支付领域的二维码技术,它实现了二维码屏幕显示到相机拍照识别获取的新型通信。基于这种新的通信方式,引入信息隐藏技术构建不可见的二维码信息,... 详细信息

移动设备的快速普及,催生了一系列新的信息获取方式,其中,最具代表性的是已广泛应用于移动支付领域的二维码技术,它实现了二维码屏幕显示到相机拍照识别获取的新型通信。基于这种新的通信方式,引入信息隐藏技术构建不可见的二维码信息,使用户在获取信息的同时,减少由于引入可见二维码而带来的对载体信息感观的不良影响。该算法针对数字视频资源,利用频率约束方法将特定信息嵌入到载体之中,通过相机或手机在视频屏幕播放时进行拍摄,获取视频信息后提取隐藏信息,实现特定信息的有效传递。同时,算法引入能量统计模型和纠错机制,以保证提取信息的准确性。大量实验测试显示,该算法能够在1~2 m距离下获得较高的信息提取准确率。

关键词：图像处理相机与屏幕通信频率约束能量统计模型二维码

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基于深度动态语义关联的短视频事件检测

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激光与光电子学进展 2024年第4期61卷 493-502页

作者：井佩光宋晓艺苏育挺天津大学电气自动化与信息工程学院天津300072

现如今,短视频事件检测展现出广阔的应用前景。现有的事件检测研究普遍缺乏对关键帧重要性程度的考虑,且多是针对事件的显性语义进行学习,忽略了潜在语义及其相关性的学习在短视频事件检测中的作用。针对上述问题,提出了一种基于深度动... 详细信息

现如今,短视频事件检测展现出广阔的应用前景。现有的事件检测研究普遍缺乏对关键帧重要性程度的考虑,且多是针对事件的显性语义进行学习,忽略了潜在语义及其相关性的学习在短视频事件检测中的作用。针对上述问题,提出了一种基于深度动态语义关联的短视频事件检测方法。首先,设计了帧重要性评估模块来获得具有区分度的帧重要性分数,其内嵌的变分自编码器和生成对抗网络联合结构可以最大程度地强化帧重要性信息;其次,设计了帧间自注意力增强模块,进一步协同帧间的重要性分数与其特征内在关联性的学习;最后,设计了动态图卷积下的隐藏属性关联学习模块来学习复杂事件的隐藏属性及事件之间的关联性,最终获得具有潜在语义信息感知的短视频检测系统并将其用于最终的短视频事件检测。在公开数据集和新构建数据集上进行了实验,实验结果表明了所提方法的有效性。

关键词：短视频语义关联特征表示图卷积

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