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Functional near-infrared spectroscopy can detect low-frequency hemodynamic oscillations in the prefrontal cortex during steady-state visual evoked potentialinducing periodic facial expression stimuli presentation

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Visual Computing for Industry,Biomedicine,and Art 2020年第1期3卷 321-328页

作者： Meng-Yun Wang Anzhe Yuan Juan Zhang yutao xiang Zhen Yuan Faculty of Health Sciences University of MacaoTaipaMacao SAR 999078China Centre for Cognitive and Brain Sciences University of MacaoTaipaMacao SAR 999078China Eastside High School 1201 SE 43rd StreetGainesvilleFL 32641USA Faculty of Education University of MacaoTaipaMacao SAR 999078China

Brain oscillations are vital to cognitive functions,while disrupted oscillatory activity is linked to various brain *** high-frequency neural oscillations(>1 Hz)have been extensively studied in cognition,the neural mechanisms underlying low-frequency hemodynamic oscillations(LFHO)<1 Hz have not yet been fully *** way to examine oscillatory neural dynamics is to use a facial expression(FE)paradigm to induce steady-state visual evoked potentials(SSVEPs),which has been used in electroencephalography studies of high-frequency brain oscillation *** this study,LFHO during SSVEP-inducing periodic flickering stimuli presentation were inspected using functional near-infrared spectroscopy(fNIRS),in which hemodynamic responses in the prefrontal cortex were recorded while participants were passively viewing dynamic FEs flickering at 0.2 *** fast Fourier analysis results demonstrated that the power exhibited monochronic peaks at 0.2 Hz across all channels,indicating that the periodic events successfully elicited LFHO in the prefrontal *** importantly,measurement of LFHO can effectively distinguish the brain activation difference between different cognitive conditions,with happy FE presentation showing greater LFHO power than neutral FE *** results demonstrate that stimuli flashing at a given frequency can induce LFHO in the prefrontal cortex,which provides new insights into the cognitive mechanisms involved in slow oscillation.

关键词： Steady state visual evoked potentials Dynamic facial expressions Functional near-infrared spectroscopy Brain oscillation

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Mapping the small-world properties of brain networks in Chinese to English simultaneous interpreting by using functional near-infrared spectroscopy

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Journal of Innovative Optical Health Sciences 2018年第3期11卷 8-19页

作者： Xiaohong Lin Victoria Lai Cheng Lei Defeng Li Zhishan Hu yutao xiang Zhen Yuan Faculty of Health Sciences University of Macao Macao SARP.R.China Department of English Faculty of Arts and Humanities University of Macao Macao SARP.R.China Centre for Studies of Translation Interpreting and Cognition University of Macao Macao

The aim of this study is to examine the small-world properties of functional brain networks inChinese to English simultaneous interpreting(SI)using functional near-infrared spectroscopy(INIRS),In particular,the fNIRS neuroimaging combined with complex network analysis wasperformed to extract the features of functional brain networks underling three translationstrategies associated with Chinese to English SI:"transcoding"that takes the"shortcut"linkingtranslation equivalents between Chinese and the English,code-mixing"that basically does notinvolve blingual procesing,and"transphrasingn that takes the long route"involving amonolingual processing of meaning in Chinese and then another monolingual processing ofmeaning in *** results demonstrated that the small-world net work topology was able todistinguish well bet ween the transcoding,code-mixing and transphrasing strategies related toChinese to English SI.

关键词： fNIRS translation simultaneous interpreting small-world brain net work

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荟萃分析——循证医学模式的重要体现

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四川精神卫生 2017年第3期30卷 220-221页

作者：项玉涛澳门大学健康科学学院

荟萃分析是循证医学重要的技术和工具,深受临床医师、指南制定者和卫生决策部门的重视,但国内精神科相关的荟萃分析在数量和质量方面尚追不上发达国家的步伐。提高我国精神科的科研素养,普及循证医学的思维,推广系统综述和荟萃分析的研... 详细信息

荟萃分析是循证医学重要的技术和工具,深受临床医师、指南制定者和卫生决策部门的重视,但国内精神科相关的荟萃分析在数量和质量方面尚追不上发达国家的步伐。提高我国精神科的科研素养,普及循证医学的思维,推广系统综述和荟萃分析的研究方法,鼓励年轻学者们开展精神科相关的荟萃分析,有利于我国精神科临床与科研更好地发展。

关键词：荟萃分析循证医学精神科

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中国接受治疗的海洛因依赖患者中反社会人格障碍患病率的荟萃分析(英文)

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上海精神医学 2014年第5期26卷 259-271页

作者：钟宝亮项玉涛操小兰李艳朱军红赵凤琴 Department of Psychiatry Chinese University of Hong Kong Affiliated Mental Health Center Tongji Medical College of Huazhong University of Science & Technology Faculty of Health Sciences University of Macao Mood Disorders Centre Beijing Anding Hospital Capital Medical University

背景：西方国家的研究持续报道海洛因成瘾者共患反社会人格障碍（Anitsocial Personality Disorder，ASPD）的比率很高，但中国海洛因成瘾者共患ASPD的报道比率变异很大，可能是因为中国的临床医生在治疗物质滥用问题时没有考虑人格问... 详细信息

背景：西方国家的研究持续报道海洛因成瘾者共患反社会人格障碍（Anitsocial Personality Disorder，ASPD）的比率很高，但中国海洛因成瘾者共患ASPD的报道比率变异很大，可能是因为中国的临床医生在治疗物质滥用问题时没有考虑人格问题。这份报告对评估中国海洛因依赖患者共患ASPD比率的研究做了系统分析。方法：我们检索了中国数据库（中国知网，万方数据知识服务平台，台湾电子期刊服务网）和西方数据库（PubMed和EMBASE）的相关研究。两位作者独立检索文献，确定符合预定纳入和排除标准的文献，评价纳入研究的文献质量，并提取用于分析的数据。使用StatsDirect 3.0进行统计分析。结果：检索到15项符合条件的研究，共有3692例海洛因依赖患者。其中仅有2项高质量研究。所有的研究都是在康复中心或医院进行的。在这些患者中合并ASPD终生患病率为30％（95％CI：23~38％），但这些研究结果的异质性很大（I2=95％，p＆lt;0.001）。男性患者的患病率显著高于女性（44％比21％），注射吸毒患者的患病率显著高于烫吸的患者（44％比27％）。研究方法较严谨的报道的海洛因依赖者ASPD患病率较高。结论：虽然现有的有关中国接受治疗的海洛因依赖患者共患ASPD的文献存在较大的方法学问题，但据我们的分析，估计这些患者中大约有三分之一的人是符合ASPD诊断标准的。进一步需要开展的工作是提高临床医生对这一问题的认识，比较伴ASPD患者与不伴ASPD患者的发病机制、治疗效果和复吸情况，制定出适合这个治疗相对困难的海洛因依赖患者亚群的针对性的干预措施并加以验证。

关键词：反社会型人格障碍:海洛因依赖患病率荟萃分析中国

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中国的精神卫生法(草案)是保护患者公民权利的里程碑(英文)

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上海精神医学 2012年第1期24卷 48-49页

作者：项玉涛李凌江 Gabor S. UNGVARI Helen F.K.CHIU Beijing Anding Hospital Capital Medical University Department of Psychiatry Chinese University of Hong Kong Mental Health Institute the Second Xiangya Hospital of Central South University The University of Notre Dame Australia/Marian Centre PerthAustralia

The draft National Mental Health Law of China was released for public consultations on June 10,2011 [1].Following wide-ranging public consultations,the draft was further amended by the Standing Committee of the National People’s Congress on October 24,2011 [2,3].Although the penultimate draft has been finalized,there are continuous debates and concerns about its potential negative effects on mental health services in *** article in this issue of the Shanghai Archives of Psychiatry by Professor Xie [4] argues that the proposed law over-emphasizes patient’s self-sufficiency and,thus,neglects traditional Chinese culture。

关键词： draft 精神卫生 Standing psychiatric released consent civil Ningbo dealing Hangzhou

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Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao xiang Feng Gao Yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

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Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi Xu Junqiu Jia Rui Mao xiang Cao Yun Xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

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Investigation of bubbles escape behavior from low basicity mold flux for high-Mn high-Al steels using 3D X-ray microscope

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 102-110页

作者： Qiang Liu xiang Li Shen Du Ming Gao Yanbin Yin Jiongming Zhang State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

During the continuous casting process of high-Mn high-Al steels,various types of gases such as Ar need to escape through the top of the *** which,the behavior of bubbles traversing the liquid slag serves as a restrictive link,closely associated with viscosity and the thickness of liquid *** contrast to two-dimensional surface observation,three-dimensional(3D)analysis method can offer a more intuitive,accurate,and comprehensive ***,this study employs a 3D X-ray microscope(3D-XRM)to obtained spatial distribution and 3D morphological characteristics of residual bubbles in mold flux under different basicity of liquid slag,different temperatures,and different holding *** results indicate that as basicity of slag increases from 0.52 to 1.03,temperature increases from 1423 to 1573 K,the viscosity of slag decreases,the floating rate of bubbles *** addition,when holding time increases from 10 to 30 s,the bubbles floating distance increases,and the volume fraction and average equivalent sphere diameter of the bubbles solidified in the mold flux gradually *** one word,increasing the basicity,temperature,and holding time leading to an increase in the removal rate of bubbles especially for the *** findings of bubbles escape behavior provide valuable insights into optimizing low basicity mold flux for high-Mn high-Al steels.

关键词： mold flux low basicity bubbles three-dimensional X-ray microscope viscosity

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Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen Li Hui Ye Xue-Zhi Zhang Jian-xiang Liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

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MECT在住院老年精神病患者中的应用情况及相关影响因素分析

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四川精神卫生 2018年第2期31卷 148-151页

作者：张新乔项玉涛王刚张庆娥李晓虹首都医科大学附属北京安定医院北京100088 澳门大学健康科学学院

目的了解改良电抽搐治疗(MECT)在住院老年精神病患者中的应用情况及相关影响因素,为对其进行MECT提供参考。方法采用回顾性分析方法,从本院电子病历数据库调取2016年在老年精神科病房住院的患者病历共403例,收集患者的社会人口学及临床... 详细信息

目的了解改良电抽搐治疗(MECT)在住院老年精神病患者中的应用情况及相关影响因素,为对其进行MECT提供参考。方法采用回顾性分析方法,从本院电子病历数据库调取2016年在老年精神科病房住院的患者病历共403例,收集患者的社会人口学及临床资料,研究MECT在老年精神病患者中的使用率,采用单因素及多因素方法探索其相关因素。结果 MECT治疗在住院老年精神病患者中的使用率为25.6%。多因素分析显示,60岁≤年龄<65岁(OR=0.433)、不合并心脏病(OR=0.362)、有自杀风险(OR=2.980)、诊断为情感障碍(OR=14.265)和精神分裂症(OR=17.260)的住院老年精神病患者更倾向于合并使用MECT。MECT组患者住院天数更少(OR=0.882),住院费用高于非MECT组(OR=5.157)。结论 MECT在精神专科医院老年患者中使用率较高,但年龄大、有心脏疾病及器质性精神障碍的老年患者应谨慎使用。

关键词： MECT 老年住院患者精神障碍治疗相关因素多因素分析

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