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Sub-Homogeneous Peridynamic Model for Fracture and Failure Analysis of Roadway Surrounding Rock

Computer Modeling in Engineering & Sciences 2024年第6期139卷 3167-3187页

作者： Shijun Zhao Qing Zhang yusong miao Weizhao Zhang Xinbo Zhao Wei Xu School of Science Qingdao University of TechnologyQingdao266520China College of Mechanics and Materials Hohai UniversityNanjing211100China Xibei Mining Co. Ltd.Shandong Energy GroupXi’an710018China

The surrounding rock of roadways exhibits intricate characteristics of discontinuity and *** address these complexities,this study employs non-local Peridynamics(PD)theory and reconstructs the kernel function to represent accurately the spatial decline of long-range ***,modifications to the traditional bondbased PD model are *** considering the micro-structure of coal-rock materials within a uniform discrete model,heterogeneity characterized by bond random pre-breaking is *** approach facilitates the proposal of a novel model capable of handling the random distribution characteristics of material heterogeneity,rendering the PD model suitable for analyzing the deformation and failure of heterogeneous layered coal-rock mass *** established numerical model and simulation method,termed the sub-homogeneous PD model,not only incorporates the support effect but also captures accurately the random heterogeneous micro-structure of roadway surrounding *** simulation results obtained using this model show good agreement with field measurements from the Fucun coal mine,effectively validating the model’s capability in accurately reproducing the deformation and failure mode of surrounding rock under bolt-supported(anchor cable).The proposed subhomogeneous PD model presents a valuable and effective simulation tool for studying the deformation and failure of roadway surrounding rock in coal mines,offering new insights and potential advancements.

关键词： Roadway surrounding rock peridynamics heterogeneous material fracture analysis numerical simulation

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Preparation of Ephedra houttuynia Granule and Its Therapeutic Mechanism of Anti-Mycoplasma gallisepticum Infection Based on Network Pharmacology

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Journal of Northeast Agricultural University(English Edition) 2024年第2期31卷 76-85页

作者： Zhang Huanqi Han Mingdong miao yusong Xu Tianqiao Liang Xin Li Jichang Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development College of Veterinary MedicineNortheast Agricultural UniversityHarbin 150030China Heilongjiang Academy of Agricultural Sciences Harbin 150030China

The use of Chinese herbal medicines can replace antibiotics that cause drug-resistance problems,which are currently necessary for disease *** this paper,a traditional Chinese medicine compound named Ephedra houttuynia granule for the treatment of Mycoplasma galliscepticum(MG)infection was ***,its action mechanism was explored through network *** optimal extraction and granulation processes of the compound were determined by high performance liquid chromatography(HPLC)method and L9 orthogonal test,and in the treatment experiment,Ephedra houttuynia granule showed a significant therapeutic effect on MG *** the study of network pharmacology,the results showed that the core targets of Ephedra houttuynia granule against MG infection were vascular endothelial growth factor(VEGFA),fos proto-oncogene(FOS),prepro-coagulation factor II(F2),etc.,the gene ontology/kyoto encyclopedia of genes and genomes(GO/KEGG)analysis results indicated that the signaling pathways of neuroactive ligand receptor interaction,cAMP,IL-17,T cell receptor,and tumor necrosis factor(TNF)might involve in anti-MG *** conclusion,this study would provide a new idea for elucidating the action mechanism of other diseases in veterinary clinic,which had a certain guiding significance.

关键词： Mycoplasma galliscepticum therapeutic mechanism network pharmacology Ephedra houttuynia granule granulating process

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基于近场动力学的窄煤柱宽度优化研究

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固体力学学报 2024年第3期45卷 363-378页

作者：赵世军章青张惟昭缪玉松赵新波青岛理工大学理学院青岛266520 河海大学力学与材料学院南京211100 山东能源集团西北矿业有限公司西安710018

煤岩体具有极为复杂的非连续变形、非均质性特征,以有限元法为代表的传统数值方法难以准确描述其损伤累积、渐进破坏全过程.基于非局部近场动力学方法(Peridynamics,PD),通过重构本构力函数核函数,推导了相应的微模量函数与临界伸长率.... 详细信息

煤岩体具有极为复杂的非连续变形、非均质性特征,以有限元法为代表的传统数值方法难以准确描述其损伤累积、渐进破坏全过程.基于非局部近场动力学方法(Peridynamics,PD),通过重构本构力函数核函数,推导了相应的微模量函数与临界伸长率.在均匀离散模型中引入用随机预断“键”表征的非均质性,使近场动力学方法能够适用于天然非均质材料与结构的非连续变形破坏分析.以付村煤矿为例,建立了近场动力学数值计算模型,分析了不同煤柱宽度条件下巷道围岩变形、破坏规律以及煤柱破损特征.研究发现:当煤柱宽度为5 m时,巷道煤壁处于挤压变形区边缘,由于支承压力剧烈变化,巷帮变形破损严重;煤柱宽度增大至6 m和7 m时,巷道煤壁逐渐远离挤压变形区,煤柱受到采空区基本顶回转运动的影响相对减弱,巷帮变形和破损量较小;当煤柱宽度继续增大,巷道围岩将进入到应力增高区域,由于外应力场支承压力较大,巷帮变形及破损量会随之增大.综合考虑巷道围岩变形破坏、煤柱破损特征,最终确定煤柱留设宽度为7 m.本文工作表明,提出的煤岩体破损分析的近场动力学模型能够有效描述煤岩体的损伤累积和渐进破坏过程,为沿空掘巷护巷煤柱尺寸优化提供了新的计算工具.

关键词：近场动力学沿空掘巷煤柱尺寸数值模拟宽度优化

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南阳重塑非饱和膨胀土的变形和含水率变化特性

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岩土工程学报 2024年第2期46卷 426-435页

作者：牛庚孙德安陈盼邵龙潭孔亮吴迪缪玉松陈凡秀青岛理工大学理学院山东青岛266520 中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室湖北武汉430071 上海大学力学与工程科学学院上海200444 大连理工大学力学系辽宁大连116085

为研究水-力作用下非饱和土变形和含水率变化特性,采用非饱和土三轴仪,对非饱和膨胀土开展了吸力平衡、等向固结和三轴剪切试验,实时监测土的变形和含水率变化,综合分析了水-力作用下土的变形和含水率随时间的变化规律,并以“双孔”模... 详细信息

为研究水-力作用下非饱和土变形和含水率变化特性,采用非饱和土三轴仪,对非饱和膨胀土开展了吸力平衡、等向固结和三轴剪切试验,实时监测土的变形和含水率变化,综合分析了水-力作用下土的变形和含水率随时间的变化规律,并以“双孔”模型为基础框架,揭示了水-力作用下土的变形和含水率变化机制。研究表明:在吸力平衡和等向固结过程,非饱和土的变形和含水率随时间变化规律不同,变形在相对较短时间内达到平衡,而含水率达到平衡耗时更长;在三轴剪切过程,剪缩变形量与孔隙水排出量随时间基本上呈线性变化。随着吸力增大,含水率达到平衡所需时间增长,但对变形达到稳定耗时影响不大。净围压增大会增长含水率达到平衡的时间,然而对变形达到稳定的耗时影响不大。改进“双孔”模型,外力基本上只影响集聚体间孔隙;含水率变化会引起土颗粒重新排列,进而影响集聚体间孔隙;集聚体间孔隙水迁移速率相对较大,颗粒间孔隙水迁移速率相对较小。

关键词：非饱和土变形含水率三轴试验双孔模型

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多采空区干式充填与带式胶结充填力学性能数值模拟研究

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金属矿山 2024年第6期 46-52页

作者：缪玉松黄飞飞朱明德李昱锦王谦源青岛理工大学理学院山东青岛266525 山东黄金集团有限公司深井开采实验室山东莱州261442

针对某萤石矿多采空区的工程概况,采用充填法治理采空区过程中提出了带式胶结充填体结构,运用3DEC离散元软件进行数值模拟计算,以空场法下采场的力学性能为基准,对传统废石干式充填与带式胶结充填2种不同充填方式下采空区进行沉降位移... 详细信息

针对某萤石矿多采空区的工程概况,采用充填法治理采空区过程中提出了带式胶结充填体结构,运用3DEC离散元软件进行数值模拟计算,以空场法下采场的力学性能为基准,对传统废石干式充填与带式胶结充填2种不同充填方式下采空区进行沉降位移场、塑性区、应力场分析。结果表明:空场法下5号矿房顶板与左侧间柱出现塑性区贯通现象,有顶板坍落,间柱溃倒的风险;传统废石干式充填下5号矿房顶板与左侧间柱塑性区面积大幅减少,但是由于废石自身重力作用顶板沉降量增加了12%;带式胶结充填下5号矿房顶板与左侧间柱塑性区仅零星分布于受拉应力较大的临空面,顶板沉降量下降了4.33%,5号矿房上下盘收敛位移较空场法下降了12%。研究表明在不考虑充填成本的情况下,采用带式胶结充填治理多采空区,具有更优良的效果。

关键词：多采空区干式充填带式胶结充填塑性区数值模拟

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起爆方式对爆轰波传播特性的影响研究

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青岛理工大学学报 2024年第3期45卷 35-42页

作者：郭建孙博闻姚颖康王海亮缪玉松张义平青岛理工大学理学院青岛266525 江汉大学爆破工程湖北省重点实验室武汉430056 山东科技大学安全与环境工程学院青岛266590 贵州大学矿业学院贵阳550025

为探究爆轰波碰撞对爆轰压力分布规律的影响,采用理论推导、数值模拟和现场试验相结合的方法,分析了不同起爆方式下炸药内部和外部爆轰压力的变化规律。研究结果表明:爆轰波发生碰撞后,依次产生正碰撞、斜碰撞及马赫反射现象,最大爆轰... 详细信息

为探究爆轰波碰撞对爆轰压力分布规律的影响,采用理论推导、数值模拟和现场试验相结合的方法,分析了不同起爆方式下炸药内部和外部爆轰压力的变化规律。研究结果表明:爆轰波发生碰撞后,依次产生正碰撞、斜碰撞及马赫反射现象,最大爆轰压力可达到稳定爆轰压力的3倍以上;采用对称双线性起爆方式时,土体聚能侧所受爆轰压力是起爆侧的2.74倍,轴向所受爆轰压力较单侧线性起爆方式提升了75%。基坑爆破试验结果表明:采用对称双线性起爆方式时,沿爆轰波碰撞聚能方向呈一字型布置起爆,炮孔间的贯通效果相较于单侧线性起爆方式得到了明显提升。

关键词：聚能爆破爆轰波碰撞起爆方式数值模拟基坑爆破

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Crack propagation and damage evolution of metallic cylindrical shells under internal explosive loading

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DEFENCE TECHNOLOGY 2024年第9期39卷 133-146页

作者： Luo, yusong Li, Weibing Li, Junbao Li, Wenbin Wang, Xiaoming Nanjing Univ Sci & Technol ZNDY Ministerial Key Lab Nanjing 210094 Peoples R China

This paper investigates the three-dimensional crack propagation and damage evolution process of metallic column shells under internal explosive loading. The calibration of four typical failure parameters for 40CrMnSiB steel was conducted through experiments and subsequently applied to simulations. The numerical simulation results employing the four failure criteria were compared with the differences and similarities observed in freeze-recovery tests and ultra-high-speed tests. This analysis addressed the critical issue of determining failure criteria for the fracture of a metal shell under internal explosive loads. Building upon this foundation, the damage parameter Dc, linked to the cumulative crack density, was defined based on the evolution characteristics of a substantial number of cracks. The relationship between the damage parameter and crack velocity over time was established, and the influence of the internal central pressure on the damage parameter and crack velocity was investigated. Variations in the fracture modes were found under different failure criteria, with the principal strain failure criterion proving to be the most effective for simulating 3D crack propagation in a pure shear fracture mode. Through statistical analysis of the shell penetration fracture radius data, it was determined that the fracture radius remained essentially constant during the crack evolution process and could be considered a constant. The propagation velocity of axial cracks ranged between 5300 m/s and 12600 m/s, surpassing the Rayleigh wave velocity of the shell material and decreasing linearly with time. The increase in shell damage exhibited an initial rapid phase, followed by deceleration, demonstrating accelerated damage during the propagation stage of the blast wave and decelerated damage after the arrival of the rarefaction wave. This study provides an effective approach for investigating crack propagation and damage evolution. The derived crack propagation and damag

关键词： Internal explosive loading Failure criterion Crack propagation Damage evolution Freeze-recovery test INTERMEDIATE PHASE SHEAR-BAND STEEL FRAGMENTATION DEFORMATION MECHANISM

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Dynamic evaluation on sealing capacity of caprocks of the Meso-Neoproterozoic reservoirs in Ordos Basin,China

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Energy Geoscience 2024年第1期5卷 99-107页

作者： yusong Yuan Yunqin Hao Rongqiang Zhang Key Laboratory of Geology and Resources in Deep Stratum Petroleum Exploration and Production Research InstituteSINOPECBeijing 102206China

The Meso-Neoproterozoic is a new play in the Ordos Basin.A deeper understanding about the dynamic relationship between the caprocks and the source rocks is *** on the comprehensive analysis of hydrocarbon source development characteristics of the Meso-Neoproterozoic and its overlying strata,as well as the formation contact relationships,lithology characteristics and exploratory drilling data,it is recognized that the Meso-Neoproterozoic contains two types of petroleum accumulation assemblage,that is,the“self-sourced indigenous”and“upper source rock-lower reservoir”*** former is mainly controlled by the development and distribution of source rocks of the Changcheng System,with the Lower Cambrian shale sequence as its *** later is controlled by the superposition between the Meso-Neoproterozoic and its overlying source rocks and this assemblage is mainly distributed in Hangjinqi and Pingliang areas with the Carboniferous-Permian shale sequence as its *** dynamic evaluation on the displacement pressure serves to reconstruct the displacement pressure history of the *** results show that the shale sequence of the Cambrian Maozhuang Formation in well XY 1 in the southern Ordos Basin has possibly acquired the ability of sealing natural gas since the early of Late *** displacement pressure increased rapidly up to 20 MPa during the Late Triassic-Jurassic and keeps at 9.2 MPa at present,indicating fair sealing *** Carboniferous-Permian caprocks in Hangjinqi area could have acquired the ability to seal natural gas in the Late Jurassic-Early Cretaceous,and the present-day displacement pressure is 9e12 MPa,indicating good sealing *** upper Paleozoic caprock in Pingliang area has been able to seal natural gas since the Early Jurassic,with a maximum displacement pressure of 23 MPa during the Cretaceous period and a current value of 17 e20 MPa,indicative of strong ability to seal natural *** sealing ability of

关键词： Ordos Basin Meso-Neoproterozoic Caprock sealing ability Displacement pressure

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Recent advances in the biosynthesis of coumarin and its derivatives

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Green Chemical Engineering 2024年第2期5卷 150-154页

作者： yusong Zou Yuxi Teng Joy Li Yajun Yan School of Chemical Materials and Biomedical EngineeringCollege of EngineeringThe University of GeorgiaAthensGA30602USA North Oconee High School BogartGA30622USA

Coumarin and its derivatives,presenting in many organisms(plants,fungi,and bacteria),are critical metabolites composed of fused benzene andα-pyrone *** unique biological and chemical properties,coumarin derivatives possess great technological potential in the agrochemicals,pharmaceuticals,food,and cosmetic *** increasing demand for coumarin derivatives accelerates the research in biological and chemical synthesis to provide stable and scalable sources of ***,the complex structures and unknown pathways have limited the progress in the biosynthesis of coumarin ***,we summarize recent developments and provide a detailed analysis of coumarin derivative biosynthetic pathways in different organisms.

关键词： Coumarin derivatives Biosynthetic pathways Biotransformation Metabolic engineering

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Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury

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Neural Regeneration Research 2024年第8期19卷 1822-1827页

作者： Yuhui Kou yusong Yuan Qicheng Li Wenyong Xie Hailin Xu Na Han Department of Trauma and Orthopedics Peking University People’s HospitalBeijingChina National Center for Trauma Medicine BeijingChina Key Laboratory of Trauma and Neural Regeneration(Peking University) Ministry of EducationBeijingChina Department of Orthopedics China-Japan Friendship HospitalBeijingChina Department of Central Laboratory and Institute of Clinical Molecular Biology Peking University People’s HospitalBeijingChina

Macrophages play an important role in peripheral nerve regeneration,but the specific mechanism of regeneration is still *** preliminary findings indicated that neutrophil peptide 1 is an innate immune peptide closely involved in peripheral nerve ***,the mechanism by which neutrophil peptide 1 enhances nerve regeneration remains *** study was designed to investigate the relationship between neutrophil peptide 1 and macrophages in vivo and in vitro in peripheral nerve crush *** functions of RAW 264.7 cells we re elucidated by Cell Counting Kit-8 assay,flow cytometry,migration assays,phagocytosis assays,immunohistochemistry and enzyme-linked immunosorbent *** debris phagocytosis was observed using the CUBIC(Clear,Unobstructed Brain/Body Imaging Cocktails and Computational analysis)optical clearing technique during Wallerian *** inflammatory factor expression in different polarization states was detected using a protein *** results showed that neutrophil peptide 1 promoted the prolife ration,migration and phagocytosis of macrophages,and CD206 expression on the surfa ce of macrophages,indicating M2 *** axonal debris clearance rate during Wallerian degeneration was enhanced after neutrophil peptide 1 *** peptide 1 also downregulated inflammatory factors interleukin-1α,-6,-12,and tumor necrosis factor-αin invo and in ***,the results suggest that neutrophil peptide 1 activates macrophages and accelerates Wallerian degeneration,which may be one mechanism by which neutrophil peptide 1 enhances peripheral nerve regeneration.

关键词： axonal debris inflammatory factors macrophages neutrophil peptide 1 peripheral nerve injury peripheral nerve regeneration RAW 264.7 cells sciatic nerve Wallerian degeneration

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