检索结果-南通市图书馆

Evolution of the“ancient Kedah”:A study on urban forms at Sungai Batu Archaeological Complex(SBAC),Bujang Valley,Kedah,Malaysia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Architectural Research 2024年第1期13卷 127-143页

作者： Mohd Hasfarisham Abd Halim Naizatul Akma Mohd Mokhtar nor Khairunnisa Talib Shyeh Sahibul Karamah Masnan ahmad Fadly Jusoh Mokhtar Saidin Kedah Malaysia Universiti Utara Malaysia KedahMalaysia Universiti Sains Malaysia PenangMalaysia

Archaeological research at the Sungai Batu Archaeological Complex(SBAC),which has been carried out until 2023,aims to complete the chronological data and urbanization process of the ancient *** study will especially prove that the ongoing urbanization process is aimed at developing the iron smelting industry and trade in ancient Kedah,especially in *** is because archaeological research at SBAC has proven that with the existence of the ancient Kedah iron smelting workshop at SBAC,river jetties,port management,rituals,and Buddhist monuments began to be erected,all of which can be determined by chronometric *** results of the chronometric dating have proven that the ancient Kedah Kingdom existed since the 6th century BC and was oriented towards the trade of iron resources,which allowed the use of the area to grow *** process of urbanization and land use clearly conforms to Lynch’s principle,which emphasizes the principles of 1)paths,2)edges,3)districts,4)nodes,and 5)landmarks in the development process of land use and urbanization in the complex.

关键词： Chronometric dating Urbanization Land use Monument Iron smelting site

Efficient Performance of Locally Processed Serum in Vero Cell Culture

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

材料科学与工程（中英文版） 2011年第4期5卷 439-446页

作者： yusilawati ahmad nor Jaafar Nuhu Jaafar Maizirwan Mel Bioprocess and Molecular Engineering Research Unit International lslamic University Malaysia Kuala Lumpur 50728 Malaysia

Serum is a vital supplement in animal cell culture. Serum used in animal cell culture is from bovine source marketed by different companies, and somewhat expensive. The aims of this work were serum treatment and screening for the best serum concentration for Vero cell culture using STATISTICA software. The best result obtained from the software was used to compare with different commercial serum (GIBCOTM and PAA). Local serum was prepared first by aseptically collecting 500 mL whole blood from disease free cattle using 50 mL anticoagulant free centrifuge tubes. Whole blood was centrifuged to separate serum and blood cells. Serum collected was treated with ultraviolet radiation and heat inactivated for 30 min at 56 °C. Vero cells were cultured in 25 cm2 T- flasks with an initial cell seeding of 4.2 × 105 cells/mL. Results obtained showed that locally made serum is comparable in terms of maximum viable cell numbers (8.0 × 105 cells/mL) compared to commercial bovine serum (8.5 × 105 cell/mL and 6.78 × 105 cell/mL) for GIBCO and PAA respectively after four days. From the study, locally prepared serum can be substituted to the commercial sera for Vero cell culture.

关键词： Vero细胞培养牛血清动物细胞培养性能紫外线辐射血药浓度抗凝血剂离心分离

Biogenic synthesis of silver nanoparticles using Persicaria odorata leaf extract: Antibacterial, cytocompatibility, and in vitro wound healing evaluation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2022年第11期70卷 10-19页

作者： Faridah Aminullah Lubis Nik ahmad Nizam NikMalek nor Suriani Sani Khairunadwa Jemon Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia Centre for Sustainable Nanomaterials(CSNano) Ibnu Sina Institute for Scientific and Industrial Research(ISI-ISIR)Universiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation) Universiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia

Biogenic synthesis of silver nanoparticles(b-AgNPs)utilising plant extract has gained the interest of researchers due to the environmentally friendly and cost-effective ***,the extent of its application in the biomedical field remains *** study evaluates the antibacterial,cytocompatibility,and wound healing activities of synthesised AgNPs using Persicaria odorata leaves extract(PO-AgNPs).The formation of PO-AgNPs was observed by visual colour changes and verified by ultraviolet-visible(UV–vis)spectrophotometer,which revealed a surface plasmon resonance(SPR)at around 440 nm,and further confirmed by X-ray diffraction(XRD).Characterisation using Fourier transform infrared(FTIR)spectroscopy showed biomolecules from the leaves extract presented together on *** emission scanning electron microscope(FESEM)and high-resolution transmission electron microscopy(HR-TEM)images revealed PO-AgNPs nanospheres with diameters of 11±3 *** diffusion test(DDT)and minimum inhibitory concentration(MIC)analysis resulted in a dose-dependent inhibition of PO-AgNPs against tested Staphylococcus epidermidis and Methicillin-resistant Staphylococcus aureus(MRSA).These results were further corroborated by time-kill kinetic assay which revealed that PO-AgNPs were bactericidal against both strains 24 h *** and in vitro wound healing evaluation against normal human fibroblast cells,HSF 1184 inferred that PO-AgNPs are non-toxic to normal cells and able to enhance cell migration as compared to the non-treated ***,PO-AgNPs are biocompatible and possess antibacterial and wound healing capabilities that are useful in biomedical applications.

关键词： Silver nanoparticles Biosynthesis Antibacterial Cytocompatibility Wound healing

In situ biosynthesized silver nanoparticle-incorporated synthesized zeolite A using Orthosiphon aristatus extract for in vitro antibacterial wound healing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2022年第8期20卷 27-34页

作者： Muhammad Hariz Asraf nor Suriani Sani Craig Denver Williams Khairunadwa Jemon Nik ahmad Nizam Nik Maliek Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 SkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation) Universiti Teknologi Malaysia81310 UTM SkudaiJohorMalaysia University of Wolverhampton Wulfuna StreetWolverhampton WV11SBEnglandUK Centre for Sustainable Nanomaterials(CSNano) Ibnu Sina Institute for Scientific and Industrial Research(ISI-SIR).Universiti Teknologi Malaysia81310 SkudaiJohorMalaysia

The capability of synthesized zeolite A(SZ)to immobilize Ag ions(Ag-SZ)and Ag nanoparticles(AgNp-SZ)were comparatively studied.A novel approach of in situ biosynthesized AgNP-incorporated synthesized zeolite A(AgNp-SZ)was synthesized at an optimum volume of 0.4mL of the Orthosiphon aristatus(***)leaves plant extract(5%)using an in situ *** comparison,Ag-Sz was produced by loading the synthesized zeolite with Ag *** synthesized materials were characterized for their morphologies and *** characterization analysesvalidate thathe biosynthesized AgNP(<100 nm)using *** leaves extract was incorporated into the zeolite *** antibacterial testing confirmed that these materials have antibacterial activity against Escherichia coliATCC11229 and Staphylococcus aureus ATCC ***/MBC analysis demonstrated that in 0.9%saline solution,AgNP-SZ had higher antibacterial activity than *** in vitro cell viability and migration assays were further examined towards human skin fibroblast cells HSF *** show that the materials are not cytotoxicto HSF1184,and the biosynthesized AgNP-SZ promotes cell migration and proliferation higher than *** research proved that the biocompatible antibacterial wound healing agent of AgNP-SZ can be synthesized using an in situ approach where the reduction process of Ag ions in the zeolite Acan be performed using plant extract.

关键词： Zeolite Orthosiphon aristatus Biosynthesis Silver nanoparticles Antibacterial In vitro wound healing

Influence of urban air pollution on the population in the Klang Valley,Malaysia:a spatial approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ecological Processes 2022年第1期11卷 126-141页

作者： Siti Haslina Mohd Shafie Mastura Mahmud Suzani Mohamad nor Lita Fadilah Rameli Ramdzani Abdullah ahmad Fariz Mohamed Centre for Research in Development Social and Environment(SEEDS)Faculty of Social Sciences and HumanitiesUniversiti Kebangsaan MalaysiaBangiSelangorMalaysia Department of Environment Faculty of Forestry and Envi-ronmentUniversiti Putra MalaysiaSerdangSelangorMalaysia Institute for Environment and Development(LESTARI) Universiti Kebangsaan MalaysiaBangiSelangorMalaysia.

Background:Urban air pollution resulting from economic growth as well as urbanization impacts the health of *** study aims to examine the spatial distribution of particulate matter(PM_(10))and the risk of exposure for the population in the Klang Valley,an urban conglomeration centred in Kuala Lumpur,***:The inverse distance weighted(IDW)interpolation technique in the ArcGIS platform was used to map the air quality from five air monitoring *** statistics of the Global Moran’s I Spatial Autocorrelation and Optimized Hot Spot Analysis were used to estimate the spatial clustering of PM_(10).The population-weighted exposure level(PWEL)technique was used to calculate the population density susceptible to PM_(10)and the AirQ+model was applied to estimate the proportion of the adult population at risk of chronic bronchitis due to long-term exposure to PM_(10)concentrations in the Klang ***:The highest annual mean PM_(10)concentrations at the Klang station ranged between 80 and 100μg/m^(3)from 2000 to 2009 and exceeded the New Malaysia Ambient Air Quality Standard(NMAAQS)and the World Health Organi-zation Air Quality Guidelines(WHOAQG)levels of 40 and 20μg/m^(3),*** Moran’s I results indicated that the statistically significant clusters of high PM_(10)in Klang present a health risk to the local *** PWEL results showed that levels of PM_(10)in Petaling Jaya exceeded the WHOAQG limits,potentially posing a health risk to the high-density *** AirQ+model found Klang to be a significantly high-risk area for chronic bronchitis among the adult population with 804,240 people(with a relative risk of 1.85)in ***:These high-risk values are due to rapid urbanization and high motor vehicle usage in the Klang Valley and therefore the impact of PM_(10)on the population needs to be *** situation should be taken seriously by the Department of Environment and Kuala Lumpur City Hall in addre

关键词： Population Urban air pollution Spatial distribution PM_(10) Adult chronic bronchitis risk

Cold Plasma:A Potential Alternative for Rice Grain Postharvest Treatment Management in Malaysia

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rice science 2022年第1期29卷 1-15页

作者： Mohd Fadthul Ikmal MISNAL norizah REDZUAN Muhamad nor Firdaus ZAINAL norhayati ahmad Raja Kamarulzaman RAJA IBRAHIM Linda AGUN School of Mechanical Engineering Faculty of EngineeringUniversiti Teknologi MalaysiaJohor Bahru 81310JohorMalaysia Department of Physics Faculty of ScienceUniversiti Teknologi MalaysiaJohor Bahru 81310JohorMalaysia

Use of pesticides,herbicides and fertilizers is among the techniques to control insect pests and fungal ***,the technique is the major contributor to severe environmental implications in terms of air,water and soil ***,variable inconsistency becomes an important issue in the implementation of inclined bed dryers,leading to significant rice grain *** plasma technology has been widely proposed as a potential alternative for rice grain postharvest treatment management due to the presence of generated ionised gas that eventually produces reactive oxygen species or reactive nitrogen *** species are used to decontaminate foodborne pathogens,mycotoxins and bacterial *** review explores the current literature regarding cold plasma treatment technology,focusing on its efficiency as the microbial decontamination medium and insect pest mortality medium,and on the enhancement functional,nutritional and cooking properties,especially in rice *** studies have successfully demonstrated the ability of cold plasma treatment to significantly reduce the microbial count of foodborne pathogens,detoxify mycotoxins,and control seedborne rice seedling bacterial *** studies have also proved that the implementation of cold plasma technology in postharvest management should be seriously considered for improving rice grain quantity and quality in Malaysia.

关键词： rice grain postharvest management cold plasma microbial decontamination bacterial control

Fenofibrate for the prevention of progression of non-proliferative diabetic retinopathy:review,consensus recommendations and guidance for clinical practice

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2022年第12期15卷 2001-2008页

作者： nor Fariza Ngah nor Asiah Muhamad Roslin Azni Abdul Aziz Shelina Oli Mohamed nor Azita ahmad Tarmizi Azian Adnan Zalifah Zakiah Asnir Zanariah Hussein Hui Foo Siew Masni Mohamed Noor Aliza Lodz Vijayamala Valayatham Institute for Clinical Research National Institutes of HealthSetia AlamSelangor 40790Malaysia Hospital Shah Alam Selangor 40000Malaysia Sector for Evidence-Based Healthcare National Institutes of HealthSetia AlamSelangor 40790Malaysia Hospital Kuala Lumpur Wilayah Persekutuan Kuala Lumpur 50586Malaysia Hospital Selayang Selangor 68100Malaysia Hospital Ampang Selangor 68000Malaysia Hospital Putrajaya Wilayah Persekutuan Putrajaya 62250Malaysia Institute for Public Health National Institutes of HealthSetia AlamSelangor 40790Malaysia

The prevalence of diabetic retinopathy(DR),and associated morbidity is high in the Asia-Pacific *** evidence suggests a potential role for fenofibrate in the prevention of progression of DR,especially in patients with cardiovascular risk,and pre-existing mild-to-moderate *** has also been found to reduce maculopathy,and the need for laser treatment in these *** these benefits of fenofibrate,a group of experts from the fields of endocrinology and ophthalmology convened in May 2017,to discuss on the the mechanism of action,and clinical efficacy of fenofibrate in *** findings from key clinical studies on fenofibrate in DR were reviewed by the experts,and consensus statements were derived to define the role of fenofibrate in the prevention and treatment of *** statements were rated based on the GRADE *** algorithm was also developed for the screening and treatment of DR in patients with type 2 diabetes(T2D),and the place of fenofibrate was defined in the *** expert recommendations,and the algorithm provided in this review will serve as a guide to the clinicians to reconsider the adjunctive use of fenofibrate for preventing the progression of DR in selected T2D patients.

关键词： diabetic retinopathy fenofibrate consensus recommendations

mRNA transcriptome profiling of human hepatocellular carcinoma cells HepG2 treated with Catharanthus roseus-silver nanoparticles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2023年第3期15卷 393-409页

作者： Nur Asna Azhar Siti Aishah Abu Bakar Marimuthu Citartan nor Hazwani ahmad Department of Biomedical Science Advanced Medical and Dental InstituteUniversiti Sains MalaysiaKepala Batas 13200Pulau PinangMalaysia Liver Malignancies Research Program Advanced Medical and Dental InstituteUniversiti Sains MalaysiaKepala Batas 13200Pulau PinangMalaysia Faculty of Bioresources and Food Industry Universiti Sultan Zainal AbidinBesut CampusBesut 22200TerengganuMalaysia

BACKGROUND The demand for the development of cancer nanomedicine has increased due to its great therapeutic value that can overcome the limitations of conventional cancer ***,the presence of various bioactive compounds in crude plant extracts used for the synthesis of silver nanoparticles(AgNPs)makes its precise mechanisms of action *** To assessed the mRNA transcriptome profiling of human HepG2 cells exposed to Catharanthus roseus ***(***)-*** The proliferative activity of hepatocellular carcinoma(HepG2)and normal human liver(THLE3)cells treated with *** were measured using MTT *** RNA samples were extracted and sequenced using BGIseq500 *** is followed by data filtering,mapping,gene expression analysis,differentially expression genes analysis,Gene Ontology analysis,and pathway *** The mean IC 50 values of *** on HepG2 was 4.38±1.59μg/mL while on THLE3 cells was 800±1.55μg/*** profiling revealed an alteration of 296 *** induced the expression of stress-associated genes such as MT,HSP and *** signalling pathways were potentially activated through MAPK,TNF and TGF pathways that are responsible for apoptosis and cell cycle *** alteration of ARF6,EHD2,FGFR3,RhoA,EEA1,VPS28,VPS25,and TSG101 indicated the uptake of ***-AgNPs via both clathrin-dependent and clathrinindependent *** This study provides new insights into gene expression study of biosynthesised AgNPs on cancer *** cytotoxicity effect is mediated by the aberrant gene alteration,and more interestingly the unique selective antiproliferative properties indicate the *** as an ideal anticancer candidate.

关键词： Catharanthus roseus HepG2 Silver nanoparticles Transcriptome oxidative stress Apoptosis Cell cycle

Liposomes as immunological adjuvants and delivery systems in the development of tuberculosis vaccine:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2022年第1期15卷 7-16页

作者： Nur Ellene Mat Luwi Suhana ahmad ahmad Suhaimi Nurfatihah Azlyna Asyikin nordin Maria Elena Sarmiento Armando Acosta Mohd nor norazmi Vuk Uskoković Rohimah Mohamud Ramlah Kadir Department of Immunology School of Medical SciencesUniversiti Sains Malaysia16150 Kubang KerianKelantanMalaysia School of Health Sciences Universiti Sains Malaysia16150 Kubang KerianKelantanMalaysia Department of Mechanical Engineering San Diego State UniversityCampanile Dr.5500San Diego 921982CAUSA TardigradeNano LLC IrvineCA 92604USA

Liposomes are phospholipid bilayer vesicles,which are biocompatible,biodegradable and nontoxic vehicles suitable for numerous drug and gene delivery *** this review,we discuss the prospect of using liposome technology in the development of a vaccine for *** remains an important health problem that requires the development of an effective vaccine,especially since the only approved vaccine for it continues to be the Bacille Calmette-Geurin(BCG)one developed 100 years *** review focuses on the different applications of liposomes toward achieving this *** liposomal formulations showing prospect in the research stage and in clinical trials are discussed.

关键词： Liposomes Tuberculosis vaccine Adjuvant Delivery system Tuberculosis