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Invisible vapor catalysis in graphene growth by chemical vapor deposition

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Nano Research 2024年第5期17卷 4259-4269页

作者： Xiucai Sun Xiaoting Liu Zhongti Sun Xintong Zhang Yuzhu Wu Yeshu zhu yuqing Song Kaicheng Jia Jincan Zhang Luzhao Sun Wan-Jian Yin Zhongfan Liu Center for Nanochemistry Beijing Science and Engineering Center for NanocarbonsBeijing National Laboratory for Molecular ScienceCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China Beijing Graphene Institute(BGI) Beijing 100095China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013China Department of Engineering University of CambridgeCambridge CB30FAUK College of Energy Soochow Institute for Energy and Materials InnovationS(SIEMIS)Jiangsu Provincial Key Laboratory for Advanced Carbon Materials and Wearable Energy TechnologiesSoochow UniversitySuzhou 215006China

Vapor catalysis was recently found to play a crucial role in superclean graphene growth via chemical vapor decomposition(CVD).However,knowledge of vapor-phase catalysis is scarce,and several fundamental issues,including vapor compositions and their impact on graphene growth,are ***,by combining density functional theory(DFT)calculations,an ideal gas model,and a designed experiment,we found that the vapor was mainly composed of Cui clusters with tens of *** vapor pressure was estimated to be~10^(-12)-10^(-1)1 bar under normal low-pressure CVD system(LPCVD)conditions for graphene growth,and the exposed surface area of Cui clusters in the vapor was 22-269 times that of the Cu substrate surface,highlighting the importance of vapor *** calculations show Cu clusters,represented by Cu17,have strong capabilities for adsorption,dehydrogenation,and decomposition of *** exhibit an adsorption lifetime and reaction flux six orders of magnitude higher than those on the Cu surface,thus providing a sufficient supply of active C atoms for rapid graphene growth and improving the surface cleanliness of the synthesized *** experimental validation showed that increasing the amount of Cu vapor improved the as-synthesized graphene growth rate and surface *** study provides a comprehensive understanding of vapor catalysis and the fundamental basis of vapor control for superclean graphene rapid growth.

关键词： vapor catalysis graphene growth chemical vapor deposition first-principles calculation

BBX7 interacts with BBX8 to accelerate flowering in chrysanthemum

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Molecular Horticulture 2023年第1期3卷 306-318页

作者： Yiwen Zhai yuqing zhu Qi Wang Guohui Wang Yao Yu Lijun Wang Tao Liu Shenhui Liu Qian Hu Sumei Chen Fadi Chen Jiafu Jiang National Key Laboratory of Crop Genetics&Germplasm Enhancement and Utilization Key Laboratory of LandscapingMinistry of Agriculture and Rural AffairsKey Laboratory of Biology of Ornamental Plants in East ChinaNational Forestry and Grassland AdministrationZhongshan Biological Breeding LaboratoryCollege of HorticultureNanjing Agricultural UniversityNanjing 210095China

The quantitative control of FLOWERING LOCUS T(FT)activation is important for the floral transition in flowering ***,the flowering regulation mechanisms in the day-neutral,summer-flowering chrysanthemum plant remain *** this study,the chrysanthemum BBX7 homolog CmBBX7 was isolated and its flowering function was *** expression of CmBBX7 showed a diurnal rhythm and CmBBX7 exhibited higher expression levels than *** of CmBBX7 in transgenic chrysanthemum accelerated flowering,whereas lines transfected with a chimeric repressor(pSRDX-CmBBX7)exhibited delayed *** single hybridization,luciferase,electrophoretic mobility shift,and chromatin immunoprecipitation assays showed that CmBBX7 directly targets *** addition,we found that CmBBX7 and CmBBX8 interact to positively regulate the expression of CmFTL1 through binding to its ***,these results highlight CmBBX7 as a key cooperator in the BBX8–FT module to control chrysanthemum flowering.

关键词： BBX family Diurnal rhythm CmFTL1 Photoperiod Flowering transition

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基于模型辨识的配电线路永久性故障判定方法

电工技术学报 2019年第5期34卷 1004-1012页

作者：丁芃朱珂朱裕庆栾悦祎电网智能化调度与控制教育部重点实验室(山东大学) 济南250061 国网临沂供电公司临沂276000

为提高配电线路重合闸成功率,提出一种相间故障检测技术,在配电变压器低压侧接入受控逆变电源,利用其给停电线路施加瞬时高压以击穿可能存在的故障点。基于产生的暂态电压、电流获取停电线路的频率响应,研究建立不同故障性质下停电线路... 详细信息

为提高配电线路重合闸成功率,提出一种相间故障检测技术,在配电变压器低压侧接入受控逆变电源,利用其给停电线路施加瞬时高压以击穿可能存在的故障点。基于产生的暂态电压、电流获取停电线路的频率响应,研究建立不同故障性质下停电线路的频域特性,进而结合模型辨识原理对停电线路内部结构进行有效辨识,判别线路故障性质以决定断路器是否重合闸。该方法现场可实施性强,既可用于配电线路自适应重合闸,也可用于停电一段时间后的线路再送电,理论、仿真和模拟实验都验证了该方法的有效性。

关键词：配电网模型辨识故障性质逆变电源

E Protein Prokaryotic Expression of Avian Infectious Bronchitis Virus

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Journal of Northeast Agricultural University(English Edition) 2008年第3期15卷 31-35页

作者： WEI Ping ZHANG Fang MING Xiaobo ZENG Xiangwei zhu yuqing WANG Lin College of Veterinary Medicine Northeast Agricultural University Harbin 150030 China College of Wild Life Resource Northeast Forestry University Harbin 150040 China

The small envelope protein （E） gene of avian infectious bronchitis virus （IBV） M41 strain was cloned, and then it was subcloned into prokaryotic expressing vector pGEX-6P-1. The recombinant plasmid was transformed into ***. BL21 and induced by IPTG. SDS-PAGE result showed that when objective protein fused with GST （about 20 ku）, the relative molecular mass of fusion protein was 38 ku. It indicated that objective protein was about 12.4 ku. The result showed that E protein was expressed successfully, it was useful to the subsequent E protein research.

关键词： avian infectious bronchitis virus (IBV) coronavirus small envelope protein (E) protein expression

Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance

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Neural Regeneration Research 2025年第3期20卷 695-714页

作者： Beibei Wu yuqing Liu Hongli Li Lemei zhu Lingfeng Zeng Zhen Zhang Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina Yangsheng College of Traditional Chinese Medicine Guizhou University of Traditional Chinese MedicineGuiyangGuizhou ProvinceChina Qinhuangdao Shanhaiguan Pharmaceutical Co. LtdQinhuangdaoHebei ProvinceChina National Clinical Research Center for Mental Disorder The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofibrillary *** amyloid plaques are the primary characteristic of Alzheimer's disease in the central nervous system and peripheral organs,targeting amyloid-beta clearance in the central nervous system has shown limited clinical efficacy in Alzheimer's disease *** abnormalities are commonly observed in patients with Alzheimer's *** liver is the primary peripheral organ involved in amyloid-beta metabolism,playing a crucial role in the pathophysiology of Alzheimer's ***,impaired cholesterol metabolism in the liver may exacerbate the development of Alzheimer's *** this review,we explore the underlying causes of Alzheimer's disease and elucidate the role of the liver in amyloid-beta clearance and cholesterol ***,we propose that restoring normal cholesterol metabolism in the liver could represent a promising therapeutic strategy for addressing Alzheimer's disease.

关键词： ABCA1 Alzheimer's disease amyloid-beta apolipoprotein E cholesterol metabolism liver liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid

上海地区临床实验室液相色谱串联质谱技术应用现状分析

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检验医学 2024年第9期39卷 853-858页

作者：方慧玲居漪欧元祝朱宇清李卿金中淦赵晓君范霄宇虞科颖上海市临床检验中心上海200126

目的了解液相色谱串联质谱(LC-MS/MS)技术在上海地区临床实验室的应用现状。方法采用自行设计的调查问卷对上海地区开展临床质谱检测的实验室进行调查,分析各实验室的专业人员、仪器设备、项目开展和运行情况。结果上海地区共有17家... 详细信息

目的了解液相色谱串联质谱(LC-MS/MS)技术在上海地区临床实验室的应用现状。方法采用自行设计的调查问卷对上海地区开展临床质谱检测的实验室进行调查,分析各实验室的专业人员、仪器设备、项目开展和运行情况。结果上海地区共有17家医疗机构的实验室开展LC-MS/MS检测工作,其中三级医院16家,二级医院1家;综合性医院14家,专科医院3家。实验室相关技术人员主要为医学检验专业人员,有69.6%的人员从事质谱检测的工作年限为1~5年,中级职称人员为54.3%。17家实验室中有16家每年校准质谱仪器1~2次,有15家每年进行1~2次维护保养。有82.4%的实验室所使用的质谱仪年故障次数为1~3次,配套的液相色谱系统年故障次数为1~5次。有3家实验室开展的LC-MS/MS项目数分别达到66、84和100项,其他实验室开展的项目数均≤33项,检测项目集中于维生素、内分泌激素和药物浓度监测(TDM)等。所有实验室均按要求开展室内质控,使用的质控品多为商品化质控品;在激素、维生素、抗菌药物TDM项目中,分别有42.9%、25.0%和50.0%的实验室使用自制质控品进行室内质控。有1家实验室使用Westgard西格玛规则进行室内质控分析,其他实验室选择Westgard多规则质控程序。对于有室间质评计划的项目,各实验室均通过参加室间质评完成实验室间的结果比对。对于无室间质评计划的项目,各实验室定期开展实验室间比对工作。结论 LC-MS/MS技术在上海地区的应用尚处于起步阶段,需要加强专业技术人员培训,完善质量保障措施,以提升临床应用中的检测质量。

关键词：液相色谱串联质谱临床实验室应用现状

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关于高校档案馆参与数字校园建设的思考

北京档案 2010年第11期 32-33页

作者：朱玉清北京外国语大学档案馆

数字化校园背景下,高校档案馆如何发挥自身作用参与学校发展建设,是一个值得探讨的问题。本文作者提出:在数字校园建设中,高校档案馆一要建设优质的档案数据库,服务于数字校园;二要发挥档案专业作用,积极参与数据中心的建设;三要培养高... 详细信息

数字化校园背景下,高校档案馆如何发挥自身作用参与学校发展建设,是一个值得探讨的问题。本文作者提出:在数字校园建设中,高校档案馆一要建设优质的档案数据库,服务于数字校园;二要发挥档案专业作用,积极参与数据中心的建设;三要培养高素质的档案人才队伍作为参与数字校园建设的最终保证。

关键词：高校档案馆数字校园

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中美经济贸易不确定性对中国技术进步的影响

中国科技论坛 2021年第11期 166-175页

作者：冯梅朱宇晴陈楚北京科技大学经济管理学院北京100083

本文在中美经贸关系不确定性加剧的背景下,选取创新指标对技术进步进行初步趋势分析,并利用DEA方法测算技术进步,运用双向固定效应模型,基于所构建的中美经济贸易不确定性指数分析其对中国技术进步的影响。结果表明:中美经济贸易不确定... 详细信息

本文在中美经贸关系不确定性加剧的背景下,选取创新指标对技术进步进行初步趋势分析,并利用DEA方法测算技术进步,运用双向固定效应模型,基于所构建的中美经济贸易不确定性指数分析其对中国技术进步的影响。结果表明:中美经济贸易不确定性对中国技术进步起倒逼升级的作用,对东部和西部地区技术进步的促进作用略大于中部地区;经济发展规模、政府科技支持、产业结构升级对技术进步均有促进作用,外商直接投资则起负向作用。基于以上分析,提出如何在复杂国际形势中稳步提升中国技术水平的政策建议。

关键词：经济贸易不确定性技术进步创新

实时动态血糖监测系统在危重症胰岛素强化治疗中作用的荟萃分析

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中华急诊医学杂志 2015年第3期24卷 320-324页

作者：王辰朱宇清帅学军中日友好医院国际医疗部第二病区北京100029

目的评价实时动态血糖监测系统（RT-CGMS）与传统间断血糖监测方法（IGM）在危重症胰岛素强化治疗（ⅡT）中的作用是否存在差异,以探讨RT-CGMS在危重症强化降低血糖治疗中的意义.方法系统性检索中文、西文文献数据库中的相关临床随机... 详细信息

目的评价实时动态血糖监测系统（RT-CGMS）与传统间断血糖监测方法（IGM）在危重症胰岛素强化治疗（ⅡT）中的作用是否存在差异,以探讨RT-CGMS在危重症强化降低血糖治疗中的意义.方法系统性检索中文、西文文献数据库中的相关临床随机对照试验（RCT）,应用Review Manager 5.2软件进行荟萃分析.评价指标包括：低血糖事件发生率、平均血糖水平、血糖达标时间比例、短期病死率等.结果共有6篇文献,总计531例患者纳入本次研究.平均血糖水平合并SMD=-0.21（95％ SMD：-0.43 ～0.01,P=0.07）;血糖达标比例时间合并SMD=0.20（95％ SMD：-0.09～0.49,P=0.18）;低血糖事件发生率合并OR=0.20 （95％ CI：0.09～0.43,P＜0.01）;短期病死率合并OR=0.35 （95％ CI：0.14～0.89,P=0.03）.结论危重症强化胰岛素治疗（ⅡT）过程中应用RT-CGMS可明显减少低血糖事件的发生率,但RT-CGMS在保持血糖于理想水平方面比较传统间断血糖监测（IGM）未见明显优势.

关键词：危重症实时动态血糖监测胰岛素强化治疗荟萃分析