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China Ocean Engineering 2024年第2期38卷 297-312页

作者： ZHANG Yi CHEN Yue yun lai LIANG Xu Ocean College Zhejiang UniversityZhoushan 316000China Hainan Institute Zhejiang UniversitySanya 572000China

This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of *** cuttlebone suffers uniaxial external compression,while underwater cylindrical shells are in a biaxial compressive stress *** suit the biaxial compressive stress state,a novel bidirectional corrugated sandwich structure is proposed to improve the bearing capacity of cylindrical *** static and buckling analysis for the sandwich shell and the unstiffened cylindrical shell with the same volume-weight ratio are studied by numerical *** is indicated that the proposed sandwich shell can effectively reduce the ratio between circumferential and axial stress from 2 to 1.25 and improve the critical buckling load by about 1.63 *** simulation shows that optimizing and adjusting the structural parameters could significantly improve the advantage of the sandwich ***,the hydrostatic pressure tests for shell models fabricated by 3D printing are carried *** to the experimental results,the overall failure position of the sandwich shell is at the center part of the sandwich *** has been found the average critical load of the proposed sandwich shell models exceeds two times that of the unstiffened shell ***,the proposed bio-inspired bidirectional corrugated sandwich structure can significantly enhance the pressure resistance capability of cylindrical shells.

关键词： bio-inspiration bidirectional corrugation sandwich shell external pressure buckling

Pharmacological Effects of Botanical Drugs on Myocardial Metabolism in Chronic Heart Failure

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Chinese Journal of Integrative Medicine 2024年第5期30卷 458-467页

作者： HU Yu-xuan QIU Sheng-lei SHANG ju-ju WANG Zi lai Xiao-lei Beijing Hospital of Traditional Chinese Medicine Capital Medical UniversityBeijing 100010China

Although there have been significant advances in the treatment of heart failure in recent years,chronic heart failure remains a leading cause of cardiovascular disease-related *** studies have found that targeted cardiac metabolic remodeling has good potential for the treatment of heart ***,most of the drugs that increase cardiac energy are still in the theoretical or testing *** research has found that botanical drugs not only increase myocardial energy metabolism through multiple targets but also have the potential to restore the balance of myocardial substrate *** this review,we summarized the mechanisms by which botanical drugs(the active ingredients/formulas/Chinese patent medicines)improve substrate utilization and promote myocardial energy metabolism by activating AMP-activated protein kinase(AMPK),peroxisome proliferator-activated receptors(PPARs)and other related *** the same time,some potential protective effects of botanical drugs on myocardium,such as alleviating oxidative stress and dysbiosis signaling,caused by metabolic disorders,were briefly discussed.

关键词： botanical drugs chronic heart failure myocardial metabolism pharmacological effects review

Inverse design of nonlinear phononic crystal configurations based on multi-label classification learning neural networks

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Chinese Physics B 2024年第10期33卷 295-301页

作者： Kunqi Huang Yiran Lin yun lai Xiaozhou Liu Key Laboratory of Modern Acoustics Institute of AcousticsNanjing UniversityNanjing 210093China School of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China State Key Laboratory of Acoustics Institute of AcousticsChinese Academy of SciencesBeijing 100190China

Phononic crystals,as artificial composite materials,have sparked significant interest due to their novel characteristics that emerge upon the introduction of *** these properties,second-harmonic features exhibit potential applications in acoustic frequency conversion,non-reciprocal wave propagation,and non-destructive *** manipulating the harmonic band structure presents a major challenge in the design of nonlinear phononic *** design approaches based on parameter adjustments to meet specific application requirements are inefficient and often yield suboptimal ***,this paper develops a design methodology using Softmax logistic regression and multi-label classification learning to inversely design the material distribution of nonlinear phononic crystals by exploiting information from harmonic transmission *** results demonstrate that the neural network-based inverse design method can effectively tailor nonlinear phononic crystals with desired *** work establishes a mapping relationship between the band structure and the material distribution within phononic crystals,providing valuable insights into the inverse design of metamaterials.

关键词： multi-label classification learning nonlinear phononic crystals inverse design

Finite barrier bound state

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Light(Science & Applications) 2024年第4期13卷 664-671页

作者： Tao Liu Kai Bai Yicheng Zhang Duanduan Wan yun lai C.T.Chan Meng Xiao Key Laboratory of Artificial Micro-and Nano-structures of Ministry of Education and School of Physics and Technology Wuhan University430072 WuhanChina. National Laboratory of Solid State Microstructures School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing University210093 NanjingChina. Department of Physics The Hong Kong University of Science and TechnologyClear Water BayKowloon999077Hong KongChina. Wuhan Institute of Quantum Technology 430206 WuhanChina

A boundary mode localized on one side of a finite-size lattice can tunnel to the opposite side which results in unwanted *** wisdom tells that the tunneling probability decays exponentially with the size of the system which thus requires many lattice sites before eventually becoming negligibly *** we show that the tunneling probability for some boundary modes can apparently vanish at specific ***,similar to bound states in the continuum,a boundary mode can be completely trapped within very few lattice sites where the bulk bandgap is not even *** intriguingly,the number of trapped states equals the number of lattice sites along the normal direction of the *** provide two configurations and validate the existence of this peculiar finite barrier-bound state experimentally in a dielectric photonic crystal at microwave *** work offers extreme flexibility in tuning the coupling between localized states and channels as well as a new mechanism that facilitates unprecedented manipulation of light.

关键词： boundary state eventually

Effect of crystal morphology of ultrahigh-nickel cathode materials on high temperature electrochemical stability of lithium ion batteries

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Journal of Energy Chemistry 2024年第1期88卷 327-335,I0008页

作者： Bi Luo Hui Li Haoyu Qi yun Liu Chuanbo Zheng Weitong Du Jiafeng Zhang lai Chen School of Metallurgy Engineering Jiangsu University of Science and TechnologyZhangjiagang 215600JiangsuChina National Engineering Laboratory for High-Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083HunanChina School of Materials Science and Engineering Beijing Key Laboratory of Environmental Science and EngineeringBeijing Institute of TechnologyBeijing 100081China

Higher nickel content endows Ni-rich cathode materials LiNi_(x)Co_yMn_(1-x-y)O_(2)(x>0.6)with higher specific capacity and high energy density,which is regarded as the most promising cathode materials for Li-ion ***,the deterioration of structural stability hinders its practical application,especially under harsh working conditions such as high-temperature *** these circumstances,it becomes particularly critical to clarify the impact of the crystal morphology on the structure and high-temperature performance as for the ultrahigh-nickel ***,we conducted a comprehensive comparison in terms of microstructure,high-temperature long-cycle phase evolution,and high-temperature electrochemical stability,revealing the differences and the working mechanisms among polycrystalline(PC),single-crystalline(SC)and Al doped SC ultrahigh-nickel *** results show that the PC sample suffers a severe irreversible phase transition along with the appearance of microcracks,resulting a serious decay of both average voltage and the energy *** the Al doped SC sample exhibits superior cycling stability with intact layered ***-situ XRD and intraparticle structural evolution characterization reveal that Al doping can significantly alleviate the irreversible phase transition,thus inhibiting microcracks generation and enabling enhanced ***,it exhibits excellent cycling performance in pouch-type full-cell with a high capacity retention of 91.8%after 500 cycles at 55℃.This work promotes the fundamental understanding on the correlation between the crystalline morphology and high-temperature electrochemical stability and provides a guide for optimization the Ni-rich cathode materials.

关键词： Single-crystalline Ultrahigh-nickel cathode High-temperature performance Phase evolution

The Boundedness of the Pullback Attractor for a 2D Micropolar Fluid Flows

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Acta Mathematicae Applicatae Sinica 2024年

作者： Wen-long SUN Chun-lin lai yun-yun LIANG School of information and mathematics Yangtze University

The purpose of this work is to investigate the boundedness of the pullback attractors for the micropolar fluid flows in two-dimensional unbounded domains. Exactly, the H1-boundedness and H2-boundedness of the pullback attractors are established when the external force F (t, x) has different regularity with respect to time variable, respectively.

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Retinal vein occlusion coinciding with paracentral acute middle maculopathy in patient with menorrhagia causing life-threatening anemia

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1760-1762页

作者： Wen-yun Lin Jin-Jhe Wang Chien-Hsiung lai School of Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Department of Ophthalmology Chang Gung Memorial HospitalChiayi 61363TaiwanChina Department of Nursing Chang Gung University of Science and TechnologyChiayi 61363TaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina

Dear Editor,We present two cases of retinal vein occlusion,one central retinal vein occlusion(CRVO)and one branch retinal vein occlusion(BRVO)respectively,coinciding with paracentral acute middle maculopathy(PAMM)on optical coherence tomography(OCT)in patients with menorrhagia causing life-threatening *** is considered a manifestation of acute ischemia affecting the deep macular capillary plexus.

关键词： anemia occlusion acute

Prognostic Nutritional Index Associates with the Severity of Silicosis:A Study from a Tertiary Class A Prevention and Treatment Institute for Occupational Diseases in China

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Biomedical and Environmental Sciences 2024年第1期37卷 122-126页

作者： HE La Gu LIANG yun lai YANG Lu Qi YUAN Hua Min Medical laboratory Department Hunan Prevention and Treatment Institute for Occupational DiseasesChangsha 410000HunanChina Laboratory Medicine Department Xiangya HospitalCentral South UniversityChangsha 410013HunanChina

Pneumoconiosis is a group of heterogeneous fibrotic lung diseases caused by inorganic mineral dust and includes coal workers’pneumoconiosis and *** involves diffuse or nodular interstitial pulmonary fibrosis caused by exposure to asbestos or silica *** is thought to have the highest number of silicosis cases,with 6,000 new cases reported annually^([1]).Currently,the clinical diagnosis and monitoring of silicosis relies mainly on a history of occupational exposure and radiological abnormalities^([2]).Therefore,determining further indicators is crucial to reflect the severity of silicosis.

关键词： diagnosis lung diseases

Composition optimization and performance prediction for ultra-stable water-based aerosol based on thermodynamic entropy theory

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Defence Technology（防务技术） 2024年第3期33卷 437-446页

作者： Tingting Kang Canjun Yan Xinying Zhao Jingru Zhao Zixin Liu Chenggong ju Xinyue Zhang yun Zhang Yan Wu College of Chemical Engineering and Materials Science Tianjin University of Science and TechnologyNo.29 13th AvenueEconomic and Technologic Development ZoneTianjin 300457China Tianjin Key Laboratory of Brine Chemical Engineering and Resource Eco-utilization Tianjin University of Science and TechnologyTianjin 300457China College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China

Water-based aerosol is widely used as an effective strategy in electro-optical countermeasure on the battlefield used to the preponderance of high efficiency,low cost and ***,the stability of the water-based aerosol is always unsatisfactory due to the rapid evaporation and sedimentation of the aerosol *** efforts have been devoted to improve the stability of water-based aerosol by using additives with different composition and ***,the lack of the criterion and principle for screening the effective additives results in excessive experimental time consumption and *** the stabilization time of the aerosol is still only 30 min,which could not meet the requirements of the perdurable ***,to improve the stability of water-based aerosol and optimize the complex formulation efficiently,a theoretical calculation method based on thermodynamic entropy theory is *** the factors that influence the shielding effect,including polyol,stabilizer,propellant,water and cosolvent,are considered within *** ultra-stable water-based aerosol with long duration over 120 min is obtained with the optimal fogging agent composition,providing enough time for fighting the electro-optic *** design guideline for choosing the additives with high phase transition temperature and low phase transition enthalpy is also proposed,which greatly improves the total entropy change and reduce the absolute entropy change of the aerosol cooling process,and gives rise to an enhanced stability of the water-based *** theoretical calculation methodology contributes to an abstemious time and space for sieving the water-based aerosol with desirable performance and stability,and provides the powerful guarantee to the homeland security.

关键词： Ultra-stable Water-based aerosol Thermodynamic entropy Composition optimization Performance prediction

Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss

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Research 2024年第1期2023卷 637-649页

作者： Hyun-Kyung So Hyebeen Kim Jinwoo Lee Chang-Lim You Chae-Eun yun Hyeon-ju Jeong Eun-ju Jin yunju Jo Dongryeol Ryu Gyu-Un Bae Jong-Sun Kang Department of Molecular Cell Biology Sungkyunkwan University School of MedicineSuwonKorea Single Cell Network Research Center Sungkyunkwan University School of MedicineSuwonKorea Research Institute of Aging-Related Diseases AniMusCureInc.SuwonKorea Drug Information Research Institute Muscle Physiome Research CenterCollege of PharmacySookmyung Women’s UniversitySeoulKorea

Neuromuscular dysfunction is tightly associated with muscle wasting that occurs with age or due to degenerative ***,the molecular mechanisms underlying neuromuscular dysfunction are currently *** studies have proposed important roles of Protein arginine methyltransferase 1(Prmt1)in muscle stem cell function and muscle *** the current study,we set out to determine the role of Prmt1 in neuromuscular function by generating mice with motor neuron-specific ablation of Prmt1(mnKO)using *** exhibited age-related motor neuron degeneration and neuromuscular dysfunction leading to premature muscle loss and ***1 deficiency also impaired motor function recovery and muscle reinnervation after sciatic nerve *** transcriptome analysis of aged mnKO lumbar spinal cords revealed alterations in genes related to inflammation,cell death,oxidative stress,and ***,mnKO lumbar spinal cords of sciatic nerve injury model or aged mice exhibited elevated cellular stress response in motor ***,Prmt1 inhibition in motor neurons elicited mitochondrial *** findings demonstrate that Prmt1 ablation in motor neurons causes agerelated motor neuron degeneration attributing to muscle ***,Prmt1 is a potential target for the prevention or intervention of sarcopenia and neuromuscular dysfunction related to aging.

关键词： degeneration impaired prevention