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适用于任意应变比的应变寿命新模型

推进技术 2018年第1期39卷 169-175页

作者：苏运来陆山西北工业大学动力与能源学院陕西西安710072

为了提高非对称应变寿命模型预估轮盘疲劳寿命的精度,通过对不同应变比下的试验数据进行多元线性拟合,建立了一种适用于试验数据应变比覆盖范围内任意应变比条件下的应变寿命新模型。结合多种材料的疲劳试验结果,对包含本模型在内的四... 详细信息

为了提高非对称应变寿命模型预估轮盘疲劳寿命的精度,通过对不同应变比下的试验数据进行多元线性拟合,建立了一种适用于试验数据应变比覆盖范围内任意应变比条件下的应变寿命新模型。结合多种材料的疲劳试验结果,对包含本模型在内的四种常用模型预测结果进行了对比分析。结果显示Morrow弹性修正模型和Morrow-Harford模型的预测结果不稳定;SWT模型预测精度一般,但稳定性较好。本文新模型对CC450不锈钢和SAE1045钢的预测结果基本在2倍分散带内;对GH4133光滑试棒的预估中位寿命比试验中位寿命仅高0.25%,对GH4133中心孔拉伸试件的预估中位寿命比试验中位寿命小3.67%,展示出很好的考虑应变比影响的疲劳寿命预测能力。

关键词：发动机轮盘疲劳寿命应变比多元线性回归体积效应

Supercoiled DNA Minicircles under Double-strand Breaks

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Chinese Journal of Polymer Science 2024年第9期42卷 1353-1359,I0007页

作者： Ye-Peng Qiao Chun-lai Ren National Laboratory of Solid State Microstructures and Department of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing210093China

Understanding how supercoiled DNA releases intramolecular stress is essential for its functional ***,the molecular mechanism underlying the relaxation process remains insufficiently *** we employed MD simulations based on the oxDNA2 model to investigate the relaxation process of a 336-base pair supercoiled minicircular DNA under double-strand breaks with two fixed *** simulations show that the conformational changes in the DNA occur continuously,with intramolecular stress release happening abruptly only when the DNA chain traverses the breakage *** relaxation process is influenced not only by the separation distance between the fixed ends but also their ***,we observe an inhibitory effect on the relaxation characterized by small angles,where short terminal loops impede DNA conformational adjustments,preserving the supercoiled *** findings elucidate the intricate interplay between DNA conformational change,DNA motion and intramolecular stress release,shedding light on the mechanisms governing the relaxation of supercoiled DNA at the molecular level.

关键词： Supercoiled DNA DNA minicircle DNA relaxation oxDNA model MD simulation

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中国共产党人伦理精神百年演进的点、线、面

伦理学研究 2023年第1期 44-49页

作者：康来云中共河南省委党校

中国共产党人伦理精神的百年演进呈现出连续性和阶段性相统一的特征,既表现为党在某一个阶段面对某一特定时代课题时的道德追求与精神风范,也表现为这些“精神坐标”串接起来所展示的完整图谱。考察中国共产党人的伦理精神,就要将其置... 详细信息

中国共产党人伦理精神的百年演进呈现出连续性和阶段性相统一的特征,既表现为党在某一个阶段面对某一特定时代课题时的道德追求与精神风范,也表现为这些“精神坐标”串接起来所展示的完整图谱。考察中国共产党人的伦理精神,就要将其置于中国共产党百年奋斗的历史进程中,既要考察作为整体和系统的伦理精神,也要考察一个个鲜明具体的“伦理精神”。厘清中国共产党人伦理精神百年演进的点、线、面,是纵向把握中国共产党人伦理精神演进轨迹的必然逻辑,也是横向理解不同时期中国共产党人伦理精神展现形态的必然要求。

关键词：伦理精神百年演进点线面

维普期刊数据库博看期刊

No Additional Cholesterol-Lowering Effect Observed in the Combined Treatment of Red Yeast Rice and Lactobacillus Casei in Hyperlipidemic Patients：A Double-Blind Randomized Controlled Clinical Trial

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Chinese Journal of Integrative Medicine 2017年第8期23卷 581-588页

作者： Chien-Ying Lee Min-Chien Yu Wu-Tsun Perng Chun-Che Lin Ming-yung Lee Ya-Lan Chang Ya-yun lai Yi-Ching Lee Yu-Hsiang Kuan James Cheng-Chung Wei Hung-Che Shih Institute of Medicine Chung Shan Medical University Taichung Taiwan 40201 China Department of Pharmacy Chung Shah Medical University Hospital Taichung Taiwan 40201 China Department of Pharmacology Chung Shan Medical University Taichung Taiwan 40201 China Department of Integrated Chinese and Western Medicine Chung Shan Medical University Hospital Taichung Taiwan 40201 China Department of Recreation Sport & Health Promotion National Pingtung University of Science and Technology Taiwan 91201 China Division of Hepatogastroenterology Department of Internal Medicine Chung Shan Medical University Hospital Taichung Taiwan 40201 China Department of Statistics and Informatics Science Providence University Taiwan 43301 China Department of Applied Cosmetology National Tainan Junior College of Nursing China Taiwan 700 Department of Internal Medicine Chung Shan Medical University HospitalGraduate Institute of Integrated Medicine China Medical University Taichung Taiwan 40201 China

Objective：To observe the effect of combining red yeast rice and Lactobacillus casei（***）in lowering cholesterol in patients with primary hyperlipidemia,the later has also been shown to remove cholesterol in in vitro ***：A double-blind clinical trial was conducted to evaluate the cholesterol-lowering effect of the combination of red yeast rice and *** patients with primary hyperlipidemia were recruited and randomized equal y to either the treatment group（red yeast rice＋***）or the control group（red yeast rice＋placebo）.One red yeast rice capsule and two *** capsules were taken twice a *** treatment lasted for 8 weeks,with an extended follow-up period of 4 *** primary endpoint was a difference of serum low-density lipoprotein cholesterol（LDL-C）level at week ***：At week 8,the LDL-C serum level in both groups was lower than that at baseline,with a decrease of 33.85±26.66 mg/dL in the treatment group and 38.11±30.90 mg/dL in the control group;however,there was no statistical difference between the two groups（P〉0.05）.The total cholesterol was also lower than the baseline in both groups,yet without a statistical difference between the two *** only statistical y significant difference between the two groups was the average diastolic pressure at week 12,which dropped by 2.67 mm Hg in the treatment group and increased by 4.43 mm Hg in the placebo group（P〈0.05）.The antihypertensive activity may be associated with *** yeast rice can significantly reduce LDL-C,total cholesterol and ***：The combination of red yeast rice and *** did not have an additional effect on lipid profiles.

关键词： red yeast rice Lactobacillus casei,low-density lipoprotein cholesterol randomizedcontrolled trial

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学术与事功平衡——郭秉文高等教育思想蠡测

南京师大学报（社会科学版） 2011年第2期 16-23页

作者：王运来南京大学教育研究院

郭秉文是获得教育学博士学位的中国第一人。他所提出的"四个平衡"广为人知。作为郭秉文大学管理思想的一部分,他所践行的"学术与事功的平衡"堪称是其"第五个平衡"。"所学者皆有所用,所用者皆本所学",学以致用、学用一致、用其所学,鼎足... 详细信息

郭秉文是获得教育学博士学位的中国第一人。他所提出的"四个平衡"广为人知。作为郭秉文大学管理思想的一部分,他所践行的"学术与事功的平衡"堪称是其"第五个平衡"。"所学者皆有所用,所用者皆本所学",学以致用、学用一致、用其所学,鼎足而三支撑起第五个平衡。有一种现象既是学术与事功平衡的题中应有之意,又是这一平衡的升华与超越,那就是引领。而引领似可说是与教学、科研、服务等量齐观的高等教育的"第四职能"。

关键词：郭秉文学术与事功平衡引领社会发展第四职能

Effect of isothermal compression and subsequent heat treatment on grain structures evolution of Al-Mg-Si alloy

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Journal of Central South University 2021年第9期28卷 2670-2686页

作者： LI Ze-cheng DENG yun-lai YUAN Man-fa ZHANG Jin GUO Xiao-bin Light Alloy Research Institute Central South UniversityChangsha 410083China State Key Laboratory of High Performance Complex Manufacturing Central South UniversityChangsha 410083China School of Materials Science and Engineering Central South UniversityChangsha 410083China

The constitutive relationships of Al-Mg-Si alloy deformed at various strain rates,temperatures and strains were *** microstructure evolution was quantitatively characterized and analyzed,including recrystallization fraction,grain sizes,local misorientation,geometrically necessary dislocation and stored strain energy during hot deformation and subsequent heat *** results show that the dislocation density and energy storage are linear with ln Z during hot deformation and subsequent heat treatment,indicating continuous recrystallization occurring in both *** higher ln Z,the dislocation density declines more sharply during subsequent heat *** ln Z is less than 28,dislocation density becomes more stable with less reduction during subsequent heat treatment after hot *** these dislocations distribute along low angle grain boundaries,the subgrain has good stability during subsequent heat *** main recrystallization mechanism during hot deformation is continuous dynamic recrystallization,accompanied by geometric dynamic recrystallization at higher ln Z.

关键词： Al-Mg-Si alloy Zener-Hollomon parameter dislocation recrystallization grain boundaries

Clinical study on the changes of the tumor target volume and organs at risk in helical tomotherapy for nasopharyngeal carcinoma

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Chinese Medical Journal 2012年第1期000卷 87-90页

作者： LU Na FENG Lin-chun CAI Bo-ning HOU Jun WANG yun-lai XIE Chuan-bin Department of Radiation Oncology People's Liberation Army General HospitalBeijing 100853China

Background Helical tomotherapy （HT） is a new image-guided intensity-modulated radiation therapy （IMRT）.The aim of this study was to evaluate the changes in the target volume and organs at risk （OARs） of patients with nasopharyngeal carcinoma （NPC） during helical *** Forty-three patients with NPC and treated via HT from March 2008 to January 2010 were reviewed *** CT scanning and plan adaptation were conducted at the 20th fraction during *** volumetric differences between the two scans were evaluated for nasopharyngeal tumor and retro- pharyngeal lymph nodes （GTVnx）,neck lymph nodes （GTVnd）,and parotid glands,as well as the axial diameter of the *** The median interval between the two scans was 25 days （23-28 days）.The volumetric decrease in GTVnx was 30.1% （median,29.8%） and in GTVnd 41.6% （median,45.9%）.The variation in the GTVnd volume was correlated with the weight loss of the *** volume of the left parotid gland decreased by 35.5% （median,33.4%） and of the right parotid glands decreased by 36.8% （median,33.5%）.The axial diameter of the head decreased by 9.39% （median,9.1%）.Conclusions The target volume and OARs of patients with NPC varied considerably during *** changes may have potential dosimetric effects on the target volume and/or OARs and influence the clinical *** CT scanning and replanning during the HT for NPC patients with a large target volume or an obvious weight loss are recommended.

关键词： nasopharyngeal carcinoma helical tomotherapy target volume organs at risk

Inverse Eigenvalue Problems and Their Associated Approximation Problems for Matrices with J-（Skew） Centrosymmetry

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Inverse Eigenvalue Problems and Their Associated Approximati...

第三届最优化与系统生物学国际研讨会

作者： Zhong-yun Liu You-Cai Duan yun-Feng lai Yu-Lin Zhang School of Math. Changsha University of Science & Technology Dept.of Math. University of MinhoCampus de Gualtar4710-057 BragaPortugal

＜正＞The inverse problems play an important role in MEG reconstructions[3,4,5,6,7].In this paper,a partially described inverse eigenvalue problem and an associated optimal approximation problem for J-centrosymmetric matrices are considered *** is shown under which conditions the inverse eigenproblem has a *** expression of its general solution is given. In case a solution of the inverse eigenproblem exists,the optimal approximation problem can be *** formula of its unique solution is ***,the case for /-skew centrosymmetric matrices is considered.

关键词： J-centrosymmetric matrices J-skew centrosymmetric Inverse eigenvalue problem optimal approximation

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浙江块状经济集群创新效应的产业升级

知识产权 2008年第2期18卷 92-94页

作者：来芸国家知识产权局专利局杭州代办处工作人员

2005年底,浙江省政府提出了由块状经济向集群效应转变的经济发展战略。这标志着浙江省的产业升级工作迈入了实质性阶段。产业升级的实质就是提高产业竞争力,而只有依靠自主创新,才能提高产业竞争力。本文分析了浙江块状经济自主创新的... 详细信息

2005年底,浙江省政府提出了由块状经济向集群效应转变的经济发展战略。这标志着浙江省的产业升级工作迈入了实质性阶段。产业升级的实质就是提高产业竞争力,而只有依靠自主创新,才能提高产业竞争力。本文分析了浙江块状经济自主创新的现状和缺乏创新动力的原因,提出了浙江块状经济要实现集群创新效应,必须进行产业升级。

关键词：块状经济产业集群自主创新产业升级