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Specific oceanographic characteristics and phytoplankton responses influencing the primary production around the Ulleung Basin area in spring

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Acta Oceanologica Sinica 2020年第2期39卷 107-122页

作者： Minji Lee Jin Ho kim yun-bae kim Chan Hong Park Kyoungsoon Shin Seung Ho baek South Sea Research Institute Korea Institute of Ocean Science and TechnologyGeoje 53201Korea Ulleungdo/Dokdo Ocean Science Station Korea Institute of Ocean Science and TechnologyUlleungdo 40205Korea Dokdo Research Center East Sea Research InstituteKorea Institute of Ocean Science and TechnologyUljin 36315Korea

The East Sea(Sea of Japan)is a marginal,semi-closed sea in the northwestern *** Ulleung Basin area,which is located near the subpolar front of the East Sea,is known to have high primary production and good fisheries in spring *** episodic wind-driven events during the spring of 2017,horizontal and vertical profiles of physical chemical biological factors were investigated at 29 stations located in the Ulleung Basin *** addition,growth responses of phytoplankton communities to nutrient additions were evaluated by bioassay experiments to understand the fluctuation of phytoplankton *** of strong northwestern wind,phytoplankton biomass was scattered and upwelling phenomenon might be suppressed in this *** phytoplankton abundances in the coastal stations were significantly higher than offshore and island *** contrast,the nutrient and chlorophyll a(Chl a)concentrations and the phytoplankton biomass were quite low in all *** was dominated group(>75.1%for coastal,40.0%for offshore and 43.6%for island stations).In the algal bioassays,the phytoplankton production was stimulated by N *** in vivo Chl a values in the+N and+NP treatments were significantly higher than the values in the control and the+P *** on the field survey,the higher nutrients in coastal waters affected the growth of diatom assemblages,however,little prosperity of phytoplankton was observed in the offshore waters despite the injection of sufficient nutrients in bioassay *** growth of phytoplankton depended on the initial cell *** of results indicated that a dominant northwestern wind led to a limited nutrients condition at euphotic layers,and the low level of biomass supply from the coasts resulted in low primary *** supplying nutrients and introducing phytoplankton through the currents are critical to maintain the high productivity in the Ulleung Basin area of the East Sea.

关键词： Ulleung Basin Ulleungdo and Dokdo spring phytoplankton blooms episodic windstorm algal bioassays primary production

Hydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity

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The Journal of Biomedical Research 2017年第6期31卷 503-511页

作者： Jieun Choi Eun Suk An Young-Hwan Ban Da Woom Seo Tae-Su kim Sung-Pyo Lee You Lin Ehn-Kyoung Choi yun-bae kim College of Veterinary Medicine and Veterinary Medical Center Chungbuk National UniversityCheongffuChungbukRepublic of Korea Anydoctor Healthcare Co. Ltd.CheonanChungnamRepublic of Korea Hotan Dichen Medicine Biotechnology Co.Ltd Hotan Xinjiang China

Particulate matters（PM） are one of the major body burdens leading to diseases. We investigated the capacities of a hydrogen-enriched water（HW） eliminating carbon nanoparticles（CNP） and carbon microparticles（CMP） from the lungs and blood, respectively. In CNP-elimination test, rats were orally administered with purified water（PW） or HW（10 or 30 mL/kg/day） for 10 weeks. At the time point of 4 weeks, the rats were challenged with intratracheal instillation of CNP（4 mg）. CNP accumulated in the airways and alveoli, and induced inflammatory lesions. Such pneumoconiosis was markedly improved by feeding HW, while PW was ineffective. CNP-induced pneumoconiosis caused systemic hematological alterations, decreasing major inflammatory cells, but markedly increasing eosinophils,indicative of an allergic reaction, which were attenuated by treatment with HW. Such PM-eliminating and antiallergic effects of HW reduced body burden as confirmed from the facilitated recovery of body and lung weights. In CMP-clearance test, mice were orally administered with PW or HW for 7 days, and intravenously injected with CMP（300 mg/kg）. CMP was rapidly eliminated from the blood in HW-fed mice. Indeed, the phagocytic indices increased to 3.5 and 6.7 folds at 10 and 30 mL/kg of HW, in comparison with a negligible effect of PW. As a mechanism study,only HW significantly inhibited lipid peroxidation in vitro Fenton reaction-mediated ·OH-generating ***, the results indicate that HW not only effectively eliminated PM from the lungs and blood by enhancing phagocytic activity, but also attenuated the lung injuries by inhibiting lipid peroxidation.

关键词： particulate matter pneumoconiosis hydrogen-enriched water particle clearance antioxidation

Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits

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World Journal of Stem Cells 2019年第12期11卷 1115-1129页

作者： Kyungha Shin Yeseul Cha Young-Hwan Ban Da Woom Seo Ehn-Kyoung Choi Dongsun Park Sung Keun Kang Jeong Chan Ra yun-bae kim College of Veterinary Medicine Chungbuk National UniversityCheongju 28644ChungbukSouth Korea Department of Biology Education Korea National University of EducationCheongju 28173ChungbukSouth Korea Biostar Stem Cell Research Institute R-BIO Co.Ltd.Seoul 07238South Korea

BACKGROUND Osteoarthritis(OA),a chronic age-related disease characterized by the slowly progressive destruction of articular cartilage,is one of the leading causes of *** a new strategy for treatment of OA,mesenchymal stem cells(MSCs)have the potential for articular cartilage ***,thrombospondin 2(TSP2)promotes the chondrogenic differentiation of *** To investigate whether TSP2 induces chondrogenic differentiation of human adipose-derived MSCs(hADMSCs)and potentiates the therapeutic effects of hADMSCs in OA *** We investigated the chondrogenic potential of TSP2 in hADMSCs by analyzing the expression of chondrogenic markers as well as NOTCH signaling genes in normal and TSP2 small interfering RNA(siRNA)-treated stem *** cruciate ligament transection surgery was performed in male New Zealand white rabbits,and 8 wk later,hADMSCs(1.7×10^6 or 1.7×10^7 cells)were injected into the injured knees alone or in combination with intra-articular injection of TSP2(100 ng/knee)at 2-d *** progression was monitored by gross,radiological,and histological *** In hADMSC culture,treatment with TSP2 increased the expression of chondrogenic markers(SOX9 and collagen Ⅱ)as well as NOTCH signaling genes(JAGGED1 and NOTCH3),which were inhibited by TSP2 siRNA *** vivo,OA rabbits treated with hADMSCs or TSP2 alone exhibited lower degree of cartilage degeneration,osteophyte formation,and extracellular matrix loss 8 wk after cell ***,such cartilage damage was further alleviated by the combination of hADMSCs and *** addition,synovial inflammatory cytokines,especially tumor-necrosis factor-α,markedly decreased following the combination *** The results indicate that TSP2 enhances chondrogenic differentiation of hADMSCs via JAGGED1/NOTCH3 signaling,and that combination therapy with hADMSCs and TSP2 exerts synergistic effects in the cartilage regeneration of OA joints.

关键词： Osteoarthritis Anterior cruciate ligament transection Human adipose tissuederived mesenchymal stem cell Thrombospondin 2 Notch signaling Cartilage regeneration

Comparative effects of plant oils and trans-fat on blood lipid profiles and ischemic stroke in rats

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The Journal of Biomedical Research 2017年第2期31卷 122-129页

作者： Haiyu Guo Young-Hwan Ban Yeseul Cha Tae-Su kim Sung-Pyo Lee Eun Suk An Jieun Choi Da Woom Seo Jung-Min Yon Ehn-Kyoung Choi yun-bae kim Veterinary Medical Center and College of Veterinary Medicine Chungbuk National University Cheongiu Chungbuk Republic of Korea Anydoctor Healthcare Co. Ltd. Cheonan Chungnam Republic of Korea

Since plant oils are believed to be better than animal fats for cerebrovascular and cardiovascular diseases, the effects of various plant oils and trans-fat on blood lipid profiles and ischemic stroke were investigated. Sprague- Dawley rats were fed a diet containing the oils or trans-fat, and then body weights, blood lipids, and effects on brain infarction and physical dysfunction induced by middle cerebral artery occlusion （MCAO） were analyzed. All the oils and trans-fat, except perilla oil, significantly increased body fats and body weight gain. Sesame oil and trans-fat specifically increased blood cholesterols and triglycerides, respectively, while perilla oil decreased both cholesterols and triglycerides. Perilla oil not only attenuated cerebral infarction, but also restored locomotor activity and rota-rod performances of MCAO rats. It is suggested that perilla oil among oils and fats could be the first choice to reduce the risk of metabolic syndrome and ischemic stroke.

关键词： plant oil trans-fat blood lipid body fat ischemic stroke physical activity

Effects of a soybean milk product on feto-neonatal development in rats

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The Journal of Biomedical Research 2018年第1期32卷 51-57页

作者： Eun Suk An Dongsun Park Young-Hwan Ban Jieun Choi Da Woom Seo Yoon Bok Lee Mi Yae Shon Ehn-Kyoung Choi yun-bae kim College of Veterinary Medicine and Veterinary Medical Center Chungbuk National University Cheongiu 28644 Republic of Korea Central Research Institute Dr. Chung's Food Co. Ltd. Cheongju 28446 Republic of Korea International Ginseng and Herb Research Institute Geumsan 312804 Republic of Korea

Since estrogenic pollutants and phytoestrogens can cause the disorder of the reproductive system, the effects of a soybean milk product（Vegemil^（？） containing 162 ppm isoflavones） on the feto-neonatal development, including male reproductive function, were investigated. Pregnant rats were fed the soybean milk（5% or 100% in drinking water）from gestational day（GD） 6 to parturition or to post-natal day（PND） 56. Specifically, the rats were divided into 4 groups： the control group（drinking water）, the GD5% group（5% soybean milk during only the GD period）, the GDPND5% group（5% soybean milk during the GD and PND periods）, and the GD-PND100% group（100% soybean milk instead of water during the GD and PND periods）. During the gestational, lactational, and developmental periods, the reproductive and developmental parameters of dams and offspring were observed. Feeding soybean milk did not affect the birth and physical development of both male and female offspring. At PND57, the weights of the testes and epididymides of F1 males significantly increased by feeding a high concentration of the soybean milk（GDPND100%）. In addition, feeding of the soybean milk during both the GD and PND periods（GD-PND5% and GDPND100%） enhanced the sperm counts and motility. The results indicate that soybean milk is safe for embryos,fetuses, and offspring, and improves the post-generational development of male reproductive function.

关键词： soybean milk feto-neonatal development reproductive function sperm quality

Prominent cycling reversibility and kinetics enabled by CaTiO3 protective layer on Zn metal for aqueous Zn-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 245-258页

作者： Gaeun Lee Yong Nam Ahn Seongjoon So Chanwoo Park Jong-Seong bae Taehyun Park Il Tae kim Jaehyun Hur School of Chemical Biological and Battery Engineering Gachon University Seongnam Busan Center Korea Basic Science Institute

Aqueous Zn-ion batteries （AZIBs） have received considerable attention owing to their various advantages such as safety,low cost,simple battery assembly conditions,and high ionic ***,they still suffer from serious problems,including uncontrollable dendrite growth,corrosion,hydrogen evolution reaction （HER） from water decomposition,electrode passivation,and unexpected *** creation of a uniform artificial nanocrystal layer on the Zn anode surface is a promising strategy for resolving these ***,we propose the use of a perovskite CaTiO3（CTO） protective layer on Zn（CTO@Zn） as a promising approach for improving the performance of *** CTO artificial layer provides an efficient pathway for Zn ion diffusion towards the Zn metal because of the high dielectric constant （εr=180） and ferroelectric characteristics that enable the alignment of dipole moments and redistribute the Zn2+ions in the CTO *** avoiding the direct contact of the Zn anode with the electrolyte solution,the uneven dendrite growth,corrosion,parasitic side reactions,and HER are mitigated,while CTO retains its mechanical and chemical robustness during ***,CTO@Zn demonstrates an improved lifespan in a symmetric cell configuration compared with bare ***@Zn shows steady overpotential （～68 m V） for 1500 h at 1 mA cm-2/0.5 mA h cm-2,excelling bare ***,when paired with the V2O5-C cathode,the CTO@Zn//V2O5-C full battery delivers 148.4 mA h g-1（based on the mass of the cathode） after 300 *** study provides new insights into Zn metal anodes and the development of high-performance AZIBs.

关键词： Perovskite

Optimization of an Artificial Intelligence Database and Camera Installation for Recognition of Risky Passenger Behavior in Railway Vehicles

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Computers, Materials & Continua 2025年第1期82卷 1277-1293页

作者： Min-kyeong kim Yeong Geol Lee Won-Hee Park Su-hwan yun Tae-Soon Kwon Duckhee Lee Railroad Test&Certification Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea Railroad Safety Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea

Urban railways are vital means of public transportation in *** than 30%of metropolitan residents use the railways,and this proportion is expected to *** enhance safety,the government has mandated the installation of closed-circuit televisions in all carriages by ***,cameras still monitored *** address this limitation,we developed a dataset of risk factors and a smart detection system that enables an immediate response to any abnormal behavior and intensive monitoring *** created an innovative learning dataset that takes into account seven unique risk factors specific to Korean railway *** data collection was conducted across the Shinbundang Line of the Incheon Transportation Corporation,and the Ui-Shinseol *** observed several behavioral characteristics and assigned unique annotations to *** also considered carriage *** performance was evaluated by camera placement and *** the camera installation plan was *** dataset will find immediate applications in domestic railway *** artificial intelligence algorithms will be verified shortly.

关键词： AI railway vehicle risk factor smart detection AI training data

High-index-contrast photonic structures:a versatile platform for photon manipulation

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Light(Science & Applications) 2022年第11期11卷 2617-2632页

作者： Young-Bin kim Jin-Woo Cho yun-Jo Lee Dukkyu bae Sun-Kyung kim Department of Applied Physics Kyung Hee UniversityYonginGyeonggido 17104Republic of Korea Hexa Solution Co. LtdSuwonGyeonggi-do 16229Republic of Korea

In optics,the refractive index of a material and its spatial distribution determine the characteristics of light ***,exploring both low-and high-index materials/structures is an important consideration in this *** cavities,which are defined as low-index bases,exhibit a variety of unusual or even unexplored optical characteristics and are used in numerous functionalities including diffraction gratings,localised optical antennas and low-loss *** this report,we discuss the fabrication of hollow cavities of various sizes(O.2-5μm in diameter)that are supported by conformal dielectric/metal shells,as well as their specific applications in the ultraviolet(photodetectors),visible(light-emitting diodes,solar cells and metalenses),near-infrared(thermophotovoltaics)and mid-infrared(radiative coolers)*** findings demonstrate that hollow cavities tailored to specific spectra and applications can serve as versatile optical platforms to address the limitations of current optoelectronic ***,hollow cavity embedded structures are highly elastic and can minimise the thermal stress caused by high *** such,future applications will likely include high-temperature devices such as thermophotovoltaics and concentrator photovoltaics.

关键词： versatile index ultraviolet

Variability of the Dokdo Abyssal Current observed in the Ulleung Interplain Gap of the East/Japan Sea

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Acta Oceanologica Sinica 2013年第1期32卷 12-23页

作者： kim yun-bae CHANG Kyung-Il PARK Jae-Hun PARK Jong Jin East Sea Research Institute Korea Institute of Ocean Science and Technology Research Institute of Oceanography School of Earth and Environmental Sciences Seoul National University Ocean Science Research Department Korea Institute of Ocean Science and Technology Department of Oceanography Kyungpook National University

Subinertial fluctuation of a strong northward deep current, which is referred to the Dokdo Abyssal Current （DAC） by Chang et al. （2009）, is investigated from current records for about 16.5 and 8.0 months in the Ulle- ung Interplain Gap of the East/lapan Sea. The current below 300 m is bottom-intensified and has nearly depth-independent flow. Near bottom, the spectral peaks of the current were found near 10, 20, and 60 d. The DAC variability near 10 d and 20 d is reasonably consistent with the linear theory of topographic Rossby waves （TRWs） in the following aspects：（1） The motion is columnar and bottom-intensified; （2） the theo- retical cutoff frequency is similar to the observation; （3） The observation-based angles of the wavenumber vector are in good agreement with the theoretical ones. The wavelengths of the TRWs with periods of near 10 d and 20 d near Dokdo are significantly shorter than those with similar timescales in the open oceans （100-250 km）. It is primarily due to the weak stratification below 300 m in the East Sea. The deep cur- rent fluctuations with periods of near 10 d and 20 d were accompanied by warm events in the upper layer resulting from eddying processes and/or meandering of the Tsushima Warm Current.

关键词： East/Iapan Sea Ulleung Interplain Gap Deep currents Topographic Ressby waves