检索结果-南通市图书馆

Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties

Military Medical Research 2024年第4期11卷 543-566页

作者： Ying Chen Xing Wang Sheng Tao Qi Wang Pan-Qin Ma Zi-Biao Li yun-Long wu Da-Wei Li Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology School of Pharmaceutical SciencesXiamen UniversityXiamen 361102FujianChina Beijing National Laboratory for Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100090China University of Chinese Academy of Sciences Beijing 100049China Senior Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijing 100091China Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)Singapore 138634Singapore

The treatment of chronic and non-healing wounds in diabetic patients remains a major medical *** reports have shown that hydrogel wound dressings might be an effective strategy for treating diabetic wounds due to their excellent hydrophilicity,good drug-loading ability and sustained drug release *** a typical example,hyaluronic acid dressing(Healoderm)has been demonstrated in clinical trials to improve wound-healing efficiency and healing rates for diabetic foot ***,the drug release and degradation behavior of clinically-used hydrogel wound dressings cannot be adjusted according to the wound *** to the intricacy of diabetic wounds,antibiotics and other medications are frequently combined with hydrogel dressings in clinical practice,although these medications are easily hindered by the hostile *** this case,scientists have created responsive-hydrogel dressings based on the microenvironment features of diabetic wounds(such as high glucose and low pH)or combined with external stimuli(such as light or magnetic field)to achieve controllable drug release,gel degradation,and microenvironment improvements in order to overcome these clinical *** responsive-hydrogel dressings are anticipated to play a significant role in diabetic therapeutic wound ***,we review recent advances on responsive-hydrogel dressings towards diabetic wound healing,with focus on hydrogel structure design,the principle of responsiveness,and the behavior of *** but not least,the advantages and limitations of these responsive-hydrogels in clinical applications will also be *** hope that this review will contribute to furthering progress on hydrogels as an improved dressing for diabetic wound healing and practical clinical application.

关键词： Responsive-hydrogel Diabetic wound Anti-inflammation Tissue remodeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ziwan-Taoren herb pair can exert an therapeutical effect in primary Sjogren’s syndrome through inhibiting the TLR/NF-κB pathway

引用

Traditional Medicine Research 2024年第8期9卷 11-22页

作者： Kuok-Tong Lei yun-Xia wu yun Lu Zi-Shan Wang Thi-Huong Nguyen Qiu-Ying Cai Wen Zhu Yue Wang First Clinical Medical College Nanjing University of Chinese MedicineNanjing 210000China Faculty of Traditional Medicine Phenikaa UniversityHa Noi 100803Vietnam Department of Rheumatology and Immunology Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210000China

Background:Ziwan and Taoren(ZT)is a classic medicine pair in the formula of Mai Dong Di Shao Decoction,has been used to treat primary Sjogren’s syndrome(pSS)for more than 20 *** its action mechanism is still *** study is aimed to reveal the potential mechanism of ZT treated pSS and discover its active compounds of ZT and therapeutic target for ***:Firstly,the potential pathways of ZT for pSS treatment were predicted through network pharmacology and GO and KEGG enrichment ***,the inter-structural relationships between active compounds of ZT and target proteins were visualized using molecular docking ***,efficacy and mechanism were conducted through in vivo experiments,such as water intake,spleen index,hematoxylin-eosin staining pathological changes,ELISA,Western Blot analysis,and immunofluorescence ***:Nine active compounds were extracted from network pharmacology,including quercitrin,luteolin,kaempferol,β-sitosterol,isorhamnetin,galangin,hederagenin,diosmetin and gibberellin *** disease targets were identified:RELA,TP53,AKT1,interleukin(IL)6,MAPK1,ESR1,IL10;with RELA being the most core *** and GO enrichment analysis indicated that ZT may act through the TLR/NF-κB/RELA inflammatory mechanism *** results of molecular docking showed that ZT’s active compounds bind well to the RELA(p65)*** vivo results demonstrated that a high dose of ZT significantly improved water intake and reduced lymphocytes infiltration in submandibular gland pathology in NOD *** expression content of AQP5 and vasoactive intestinal peptide in the submaxillary gland was significantly increased,while levels of inflammatory factors such as tumor necrosis factor-α,IL-6,and IL-1βalong with protein expressions including toll-like receptor4,p-p65 and p-IKKα/βin NF-κB pathway were ***:The ZT treatment exhibits a promising efficacy in mitigating dryness symptoms of pSS,potentially attr

关键词： traditional Chinese medicine primary Sjogren’s syndrome NF-κB RELA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Metabolic and microbial changes in light-vented bulbul during recent northward range expansion

引用

Current Zoology 2024年第1期70卷 24-33页

作者： yun wu Ying Xiong Yanzhu Ji Yalin Cheng Qianghui Zhu Xiaolu Jiao Yongbin Chang Na Zhao Jing Yang Fumin Lei Gang Song Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China College of Life Science University of Chinese Academy of SciencesBeijing 100049China Department of Zoology College of Life scienceSichuan Agricultural UniversityYa'an 625099SichuanChina Henan Engineering Research Center of Bird-Related Outage Zhengzhou Normal UniversityZhengzhou 450044China School of Ecology and Environment Anhui Normal UniversityWuhu 241002AnhuiChina School of Environmental Science and Engineering Shaanxi University of Science and TechnologyXian 710021China Centerfor Excellence inAnimal Evolutionand Genetics Chinese Academy of SciencesKunming 650223China

Endotherms recently expanding to cold environments generally exhibit strong physiological acclimation to sustain high body *** this process,gut microbes likely play a considerable role in host physiological functions,including digestion and *** light-vented bulbul Pycnonotus sinensis represents one such *** used to be restricted to the Oriental realm but expanded its distribution range north to the Palearctic areas during the past few ***,we explored the seasonal dynamics of the resting metabolic rate(RMR)and microbiota for local and newly colonized populations of the *** results showed that the mass-adjusted RMR and body mass were pos-itively correlated with latitude variations in both ***,the gut microbiota showed a corresponding variation to the northern cold *** the two northern populations,the alpha diversity decreased compared with those of the two southern *** differences were detected in dominant phyla,such as Firmicutes,Bacteroidetes,Proteobacteria,and Desulfobacterota in both *** core microbiota showed geographic differences in the winter,including the elevated relative abundance of 5 species in northern ***,to explore the link between microbial communities and host metabolic thermogenesis,we conducted a correlation analysis between microbiota and mass-adjusted *** found that more genera were significantly correlated with mass-adjusted RMR in the wintering season compared to the breeding season(71 vs.23).These results suggest that microbiota of the lighted-vented bulbul linked with thermogenesis in diversity and abundance under northward expansion.

关键词： bird body mass gutmicrobiota RMR season

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Airfoil friction drag reduction based on grid-type and super-dense array plasma actuators

引用

Plasma Science and Technology 2024年第2期26卷 94-103页

作者：方子淇宗豪华吴云梁华苏志 School of Aerospace Engineering Xi'an Jiaotong UniversityXi'an 710049People's Republic of China School of Mechanical Engineering Xi'an Jiaotong UniversityXi'an 710049People's Republic of China National Key Lab of Aerospace Power System and Plasma Technology Air Force Engineering UniversityXi'an 710038People's Republic of China

To improve the cruise flight performance of aircraft, two new configurations of plasma actuators(grid-type and super-dense array) were investigated to reduce the turbulent skin friction drag of a low-speed airfoil. The induced jet characteristics of the two actuators in quiescent air were diagnosed with high-speed particle image velocimetry(PIV), and their drag reduction efficiencies were examined under different operating conditions in a wind tunnel. The results showed that the grid-type plasma actuator was capable of producing a wall-normal jet array(peak magnitude: 1.07 m/s) similar to that generated in a micro-blowing technique, while the superdense array plasma actuator created a wavy wall-parallel jet(magnitude: 0.94 m/s) due to the discrete spanwise electrostatic forces. Under a comparable electrical power consumption level,the super-dense array plasma actuator array significantly outperformed the grid-type configuration,reducing the total airfoil friction drag by approximately 22% at a free-stream velocity of 20 m/*** magnitude of drag reduction was proportional to the dimensionless jet velocity ratio(r), and a threshold r = 0.014 existed under which little impact on airfoil drag could be discerned.

关键词： plasma actuator flow control drag reduction airfoil

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent advances and trends of single-atom catalysts for proton exchange membrane fuel cell cathodes

ChemPhysMater

引用

ChemPhysMater 2024年第2期3卷 143-156页

作者： Zihao Wan Feng Liu Hongfei Xu Shuaili Zhao Zhen An Zizai Ma Zhonghua Zhang yun wu Xiaoguang Wang Laboratory of Advanced Materials and Energy Electrochemistry Institute of New Carbon MaterialsCollege of Material Science and EngineeringTaiyuan University of TechnologyTaiyuan 030024China Datong Innoreagen Power Technology Co. LtdDatong 037000China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China Shanxi Key Laboratory of Gas Energy Efficient and Clean Utilization Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) School of Materials Science and EngineeringShandong UniversityJinan250061China Department of Materials Science and Engineering Guangdong University of Petrochemical TechnologyMaoming 525000China

Proton exchange membrane fuel cells(PEMFCs),which have the advantages of high-power density,zero emission,and low noise,are considered ideal electrochemical conversion systems for converting hydrogen(H2)and oxy-gen(O_(2))/air into ***,the oxygen reduction reaction(ORR),which is accompanied by multiple electrons,results in voltage loss and low conversion efficiency of ***,PEMFCs mainly use high-load precious platinum(Pt)to promote the ORR process;however,the high cost of Pt hinders the widespread commercialization of *** the past few years,metal-nitrogen-carbon single-atom catalysts(M-N-C SACs)have attracted considerable attention and have been recognized as potential Pt-based catalysts owing to their outstanding ORR *** review briefly introduces the components of ***,we discuss the catalytic mechanisms of the M-N-C SACs for the ***,the latest advances in noble,non-noble,and heteroatom-doped M-N-C SACs used as ORR and PEMFCs cathode catalysts are systematically *** sum-mary,we have outlined the current challenges and proposed a future perspective of M-N-C SACs for PEMFCs cathodes.

关键词： Proton exchange membrane fuel cells Oxygen reductionreaction Cathode Platinum-based catalysts Metal-nitrogen-carbon single-atom catalysts

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lattice strain induced by trace Pt single atoms in nickel for accelerating industrial hydrogen evolution

引用

Journal of Energy Chemistry 2024年第11期 503-511页

作者： Rui Yao yun wu Kaiyang Zhang Shuhui Fan Qiang Zhao Jinping Li Guang Liu College of Chemical Engineering and Technology Shanxi Key Laboratory of Gas Energy Efficient and Clean Utilization Taiyuan University of Technology Shanxi Research Institute of Huairou Laboratory

Strategically designing the electrocatalytic system and cleverly inducing strain is an effective approach to balance the cost and activity of Pt-based electrocatalysts for industrial-scale hydrogen ***,we present a unipolar pulsed electrodeposition（UPED） strategy to induce strain in the Ni lattice by introducing trace amounts of Pt single atoms（SAs）(0.22 wt%).The overpotential decreased by 183 mV at 10 mA cm-2in 1.0 M KOH after introducing trace amounts of *** industrial electrolyzer,assembled with PtSAsNi cathode and a commercial NiFeOxanode,requires a cell voltage of 1.90 V to attain 1 A cm-2of current density and remains stable for 280 h,demonstrating significant potential for practical *** aberration corrected scanning transmission electron microscopy（AC-STEM）,X-ray absorption（XAS）,and geometric phase analysis（GPA） indicate that the introduction of trace amounts of Pt SAs induces tensile strain in the Ni lattice,thereby altering the local electronic structure and coordination environment around cubic Ni for enhancing the water decomposition kinetics and fundamentally changing the reaction *** doping-strain strategy showcases conformational relationships that could offer new ideas to construct efficient hydrogen evolution reaction（HER） electrocatalysts for industrial hydrogen production in the future.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

“爱无差等”与“爱有差等”的统一:重释墨家“兼爱”

引用

湖北大学学报（哲学社会科学版） 2024年第4期51卷 32-39页

作者：武云上海交通大学人文学院上海200240

先秦以来,将墨家的“兼爱”等同于“爱无差等”逐渐成为中国思想史上的主流观点,对兼爱的许多批判也由此而来。但仔细辨析《墨子》文本,可以进行这样的解读:一方面,墨家兼爱在要求不可亏害任何人的底线意义上,确实坚持人与人之间的“爱... 详细信息

先秦以来,将墨家的“兼爱”等同于“爱无差等”逐渐成为中国思想史上的主流观点,对兼爱的许多批判也由此而来。但仔细辨析《墨子》文本,可以进行这样的解读:一方面,墨家兼爱在要求不可亏害任何人的底线意义上,确实坚持人与人之间的“爱无差等”,否定了特殊性人际之爱在道德上的绝对至上性;另一方面,在满足了这一底线要求的前提下,墨家兼爱并没有否定、反而积极肯定了人与人之间的“爱有差等”,为实现特殊性人际之爱提供了保障。兼爱不会基于任何“差等”而使任何人受到不义的亏害,不至于使“爱有差等”缺少正当性约束,造成以亏害人为代价去爱特定人的不义后果,从而保障了“爱有差等”在道德上的正当性,由此达成了“爱无差等”与“爱有差等”的内在统一。从墨家兼爱观中的这种统一,可以看到“平等”和“差等”并不是必然对立的,其所体现的“平等”是在不可亏害任何人的底线意义上的,是为了确保每个人的基本权益都得到保障。

关键词：墨家兼爱不可亏人爱无差等爱有差等

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

“全民阅读”概念史考析——基于知识建构、制度演进、文明交融三重脉络

引用

编辑之友 2024年第9期 10-21页

作者：吴赟浙江大学传媒与国际文化学院浙江杭州310058

文章对知识建构、制度演进、文明交融三重脉络中的“全民阅读”概念史予以深度考析。通过研究,有三方面发现:其一,在出版学“意义之网”中,“全民阅读”是一个连接诸多节点的重要纽带,这一标识性概念反映了中国的经验和价值,具有特定的... 详细信息

文章对知识建构、制度演进、文明交融三重脉络中的“全民阅读”概念史予以深度考析。通过研究,有三方面发现:其一,在出版学“意义之网”中,“全民阅读”是一个连接诸多节点的重要纽带,这一标识性概念反映了中国的经验和价值,具有特定的中国内涵,为出版学知识体系提供了新的知识增量;其二,“全民阅读”概念的“制度化”进程,折射了当代中国社会转型期探索经验和社会理念、文化生态之变化,体现了“全民阅读”概念在中国经历的政策化乃至观念化的过程;其三,“全民阅读”是一个已经在中国社会被普遍接受并形成相当话语力量、反映本土经验和价值、深入社会大众日常生活的标识性概念。归纳而言,这一概念具有三方面的特征:兼具国际性和本土化两重属性;立足本土实践经验,反映本土社会事实;根植本土阅读文化,反映本土阅读价值观念。

关键词：全民阅读概念史知识建构制度演进文明交融

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessing the Applicability of Multi-Source Precipitation Products over the Chinese Mainland and Its Seven Regions

引用

Journal of Tropical Meteorology 2024年第3期30卷 275-288页

作者： TIAN Wei wu yun-long LIN Chen ZHANG Jing-guo LIM KAM SIAN Kenny Thiam Choy School of Computer and Software Nanjing University of Information Science&TechnologyNanjing 210044 China School of Atmospheric Science and Remote Sensing Wuxi UniversityWuxiJiangsu 214105 China

Satellite-based and reanalysis precipitation products provide valuable information for various ***,their performance varies widely across regions due to different data sources and production *** paper evaluated the daily performance of four precipitation products(MSWEP,ERA5,PERSIANN,and TRMM)for seven regions of the Chinese mainland,using observations from 2462 ground stations across the country as a *** used four statistical and four classification indicators to describe their spatial and temporal accuracy,and capability to detect precipitation events while analyzing their *** results show that according to the precipitation char-acteristics and accuracy of different types of precipitation products over the Chinese mainland,MSWEP was the most suitable product over the Chinese mainland,having the lowest root mean square error and mean absolute error,along with the highest coefficient of *** was followed by TRMM and ERA5,whereas PERSIANN lagged behind in terms of *** terms of different regions,MSWEP still performed well,especially in North China and East *** accuracy of the four precipitation products was relatively low in the summer months,and they all overestimated in the northwest *** other months,MSWEP and TRMM were better than PERSIANN and *** four precipitation products had good detection performance over the Chinese mainland,with probability of detection above ***,with the increase of precipitation threshold,the detection capability of the four products decreased,and MSWEP and ERA5 had good detection capability for moderate ***’s detection capability for heavy rain and rainstorms was better than that of the other three products,and PERSIANN’s detection capability for moderate rain,heavy rain and rainstorms was relatively poor,with a large deviation.

关键词： precipitation product MSWEP TRMM ERA5 PERSIANN

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An epidermal electrode based triboelectric walking energy harvester for wearable wireless sensing applications

引用

Science China(Technological Sciences) 2024年第3期67卷 949-957页

作者： CHANG ShiYuan LIU FuHai CHEN JinKai XIA LianBin ZHOU Hao JIANG JingYang DONG Kang ZHANG ChenHao wu yun CHEN Jin XUAN Weipeng SUN LingLing JIN Hao DONG ShuRong LUO JiKui Ministry of Education Key Laboratory of RF Circuits and Systems Hangzhou Dianzi UniversityHangzhou 310018China Special Equipment College Hangzhou Vocational&Technical CollegeHangzhou 310018China College of Information Science and Electronic Engineering Zhejiang UniversityHangzhou 330027China ZJU-Hangzhou Global Scientific and Technological Innovation Center Zhejiang UniversityHangzhou 311200China

Harvesting bio-kinetic energy using a triboelectric nanogenerator(TENG) is one of the promising routes to solve the sustainable energy supply problem for wearable electronics. However, additional materials, complex fabricating processes or specific mechanical structures are needed for existing TENGs to harvest bio-kinetic energy. Besides, they need to be tightly attached to the human body, which may result in detachment and malfunction under tense human motion. Herein, an intrinsic epidermal electrode-based TENG(E-TENG) is proposed to harvest human walking energy. The wearing shoes and ground are used as tribo-materials, and the human epidermis is used as the back electrode of the E-TENG. Compared with the traditional TENGs,the E-TENG does not need any additional tribo-materials and complex mechanical structures. Under optimal conditions, the voltage output of E-TENG can reach 914 V. E-TENG has been used as a self-powered warning sensor and pedometer sensor for demonstration. Furthermore, E-TENG based self-powered wireless sensor system has been developed using a newly designed micro energy electronic switch(MEES). Ambient ultraviolet intensity, temperature and humidity information can be monitored and then transmitted to mobile phone every 3.5 min, demonstrating great potential for widespread wearable applications.

关键词： triboelectric nanogenerator wearable wireless sensing self-powered

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：