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Plant virology in the 21st century in China:Recent advances and future directions

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Journal of Integrative Plant Biology 2024年第3期66卷 579-622页

作者： Jianguo Wu Yongliang Zhang Fangfang Li Xiaoming Zhang Jian Ye Taiyun Wei Zhenghe Li Xiaorong Tao Feng Cui Xianbing wang Lili Zhang Fei Yan Shifang Li yule Liu Dawei Li Xueping Zhou Yi Li State Key Laboratory for Ecological Pest Control of Fujian and Taiwan Crops Vector-borne Virus Research CenterCollege of Plant ProtectionFujian Agriculture and Forestry UniversityFuzhou 350002China State Key Laboratory of Plant Environmental Resilience and Ministry of Agriculture Key Laboratory of Soil Microbiology College of Biological SciencesChina Agricultural UniversityBeijing 100193China State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Plant Genomics Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Rice Biology Institute of BiotechnologyZhejiang UniversityHangzhou 310058China Department of Plant Pathology The Key Laboratory of Plant ImmunityNanjing Agricultural UniversityNanjing 210095China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Institute of Plant VirologyNingbo UniversityNingbo 315211China MOE Key Laboratory of Bioinformatics Center for Plant BiologySchool of Life SciencesTsinghua UniversityBeijing 100084China State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China

Plant viruses are a group of intracellular pathogens that persistently threaten global food security.Significant advances in plant virology have been achieved by Chinese scientists over the last 20 years,including basic research and technologies for preventing and controlling plant viral diseases.Here,we review these milestones and advances,including the identification of new crop-infecting viruses,dissection of pathogenic mechanisms of multiple viruses,examination of multilayered interactions among viruses,their host plants,and virus-transmitting arthropod vectors,and in-depth interrogation of plantencoded resistance and susceptibility determinants.Notably,various plant virus-based vectors have also been successfully developed for gene function studies and target gene expression in plants.We also recommend future plant virology studies in China.

关键词： China emerging plant viruses plant virology plant resistance/susceptibility to viral infection plant-virus transmission vector interactions plant virus-based vectors viral pathogenesis

能量感知的点云视频流传输与边缘卸载联合优化

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通信学报 2024年第5期45卷 80-89页

作者：刘威朱雨乐付晨王希华中科技大学电子信息与通信学院湖北武汉430074

针对点云视频流媒体传输需要调度各类计算和传输资源,而现有工作较少考虑终端显示设备的计算任务带来的能耗问题,提出了一种移动边缘计算辅助的点云视频流传输方案,根据接入带宽和点云视频内容将部分计算任务从终端卸载到边缘完成。该... 详细信息

针对点云视频流媒体传输需要调度各类计算和传输资源,而现有工作较少考虑终端显示设备的计算任务带来的能耗问题,提出了一种移动边缘计算辅助的点云视频流传输方案,根据接入带宽和点云视频内容将部分计算任务从终端卸载到边缘完成。该方案建立了一个联合优化模型,在网络资源、终端和边缘算力资源的约束下,最大化用户观看体验收益并最小化终端设备能耗。实验表明,相比于对比方案,所提方案在不同条件下均可提升用户观看质量并降低终端设备能耗。

关键词：点云视频流能量感知移动边缘计算联合优化

Rod-shape inorganic biomimetic mutual-reinforcing MnO2-Au nanozymes for catalysis-enhanced hypoxic tumor therapy

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Nano Research 2020年第8期13卷 2246-2258页

作者： Lifang Yang Chuchu Ren Min Xu Yilin Song Qianglan Lu Yule Wang Yan Zhu Xinxing wang Nan Li Tianjin Key Laboratory of Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin300072China Tianjin State Key Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineBeihua South RoadJingHai DistrictTianjin301617China Research and Development Center of TCM Tianjin International Joint Academy of Biotechnology and Medicine220 Dongting RoadTEDATianjin300457China Tianjin Institute of Environmental and Operational Medicine 1 Dali RoadHeping DistrictTianjin300050China

Biomimetic nanozymes possessing natural enzyme-mimetic activities have been extensively applied in nanocatalytic tumor therapy.However,engineering hybrid biomimetic nanozymes to achieve superior nanozyme activity remained to be an intractable challenge in hypoxic tumors.Herein,a rod-like biomimetic hybrid inorganic MnO2-Au nanozymes are developed,where MnO2 and ultrasmall Au nanoparticles(NPs)are successively deposited on the mesoporous silica nanorod to cooperatively improve the O2 content and thermal sensitivity of hypoxic solid tumors guided by multi-modal imaging.Under the catalyzing of MnO2,the intratumoral H2O2 is decomposed to greatly accelerate O2 generation,which could boost the curative effect of radiation therapy(RT)and further enhance the Au-catalyzed glucose oxidation.Mutually,the Au NPs can steadily and efficiently catalyze the oxidation of glucose in harsh tumor microenvironment,thus sensitizing tumor cells to thermal ablation for mild photothermal therapy and further promoting the catalytic efficiency of MnO2 with the self-supplied H2O2/H+.As a result,this mutual-reinforcing cycle can endow the nanoplatform with accelerated O2 generation,thus alleviating hypoxic environment and further boosting RT effect.Furthermore,acute glucose consuming can induce downregulation expression of heat shock protein(HSP),achieving starvation-promoted mild photothermal therapy.This synthesized hybrid nanozymes proves to be a versatile theranostic agent for nanocatalytic cancer therapy.

关键词： nanozyme self-supplied mutual-reinforcing hypoxia catalysis-enhanced therapy

Competition between anthocyanin and kaempferol glycosides biosynthesis affects pollen tube growth and seed set of Malus

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Horticulture Research 2021年第1期8卷 2439-2455页

作者： Weifeng Chen Zhengcao Xiao Yule Wang Jinxiao wang Rui Zhai Kui Lin-wang Richard Espley Fengwang Ma Pengmin Li State Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple College of HorticultureNorthwest A&F UniversityYanglingShaanxi 712100China College of Food Science and Technology Northwest UniversityXi'anShaanxi 710069China The New Zealand Institute for Plant and Food Research Ltd Private Bag92169 AucklandNew Zealand

Flavonoids play important roles in regulating plant growth and development.In this study,three kaempferol 3-O-glycosides were identi fi ed and mainly accumulated in fl owers but not in leaves or fruits of Malus.In Malus,fl ower petal color is normally white,but some genotypes have red fl owers containing anthocyanin.Anthocyanin biosynthesis appears to be in competition with kaempferol 3-O-glycosides production and controlled by the biosynthetic genes.The white fl ower Malus genotypes had better-developed seeds than the red fl ower genotypes.In fl owers,the overexpression of MYB10 in Malus domestica enhanced the accumulation of anthocyanin,but decreased that of kaempferol 3-O-glycosides.After pollination the transgenic plants showed slower pollen tube growth and fewer developed seeds.Exogenous application ofdifferent fl avonoid compounds suggested that kaempferol 3-O-glycosides,especially kaempferol 3-O-rhamnoside,regulated pollen tube growth and seed set rather than cyanidin or quercetin 3-O-glycosides.It was found that kaempferol 3-O-rhamnoside might regulate pollen tube growth through effects on auxin,the Rho of plants(ROP)GTPases,calcium and the phosphoinositides signaling pathway.With the inhibition of auxin transport,the transcription levels of Heat Shock Proteins(HSPs)and ROP GTPases were downregulated while the levels were not changed or even enhanced when blocking calcium signaling,suggesting that HSPs and ROP GTPases were downstream of auxin signaling,but upstream of calcium signaling.In summary,kaempferol glycoside concentrations in pistils correlated with auxin transport,the transcription of HSPs and ROP GTPases,and calcium signaling in pollen tubes,culminating in changes to pollen tube growth and seed set.

关键词： kaempferol slower upstream

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互质阵MIMO雷达DOA估计性能综合分析

电光与控制 2024年第1期31卷 97-103页

作者：杨清亮王鸿帧张宇乐陈晨中国人民解放军93575部队河北承德067000 空军工程大学西安710000 中国人民解放军95980部队湖北襄阳441000

以非相干信号源为研究对象,综合分析了单基地互质阵多输入多输出(MIMO)雷达的波达方向(DOA)估计性能。首先,在总结归纳互质阵结构特点的基础上推导了基于和联合阵列及和差联合阵列的单基地MIMO雷达测向信号模型,然后结合多重信号分类(MU... 详细信息

以非相干信号源为研究对象,综合分析了单基地互质阵多输入多输出(MIMO)雷达的波达方向(DOA)估计性能。首先,在总结归纳互质阵结构特点的基础上推导了基于和联合阵列及和差联合阵列的单基地MIMO雷达测向信号模型,然后结合多重信号分类(MUSIC)算法,分别详细介绍了基于和联合阵列及和差联合阵列的单基地MIMO雷达DOA估计方法,最后,进行与等阵元数的均匀线阵MIMO雷达的对比仿真实验,验证了互质阵MIMO雷达DOA估计性能的优越性。

关键词：互质阵列多输入多输出雷达波达方向估计和联合阵列和差联合阵列

NIR-II driven plasmon-enhanced cascade reaction for tumor microenvironment-regulated catalytic therapy based on bio-breakable Au-Ag nanozyme

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Nano Research 2020年第8期13卷 2118-2129页

作者： Min Xu Qianglan Lu Yiling Song Lifang Yang Chuchu Ren Wen Li Ping Liu Yule Wang Yan Zhu Nan Li Tianjin Key Laboratory of Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin300072China Tianjin State Key Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin301617China Research and Development Center of TCM Tianjin International Joint Academy of Biotechnology and MedicineTianjin300457China

Emerging nanozymes with natural enzyme-mimicking catalytic activities have inspired extensive research interests due to their high stability,low cost,and simple preparation,especially in the field of catalytic tumor therapy.Here,bio-breakable nanozymes based on glucose-oxidase(GOx)-loaded biomimetic Au–Ag hollow nanotriangles(Au–Ag–GOx HTNs)are designed,and they trigger an near-infrared(NIR)-II-driven plasmon-enhanced cascade catalytic reaction through regulating tumor microenvironment(TME)for highly efficient tumor therapy.Firstly,GOx can effectively trigger the generation of gluconic acid(H+)and hydrogen peroxide(H2O2),thus depleting nutrients in the tumor cells as well as modifying TME to provide conditions for subsequent peroxidase(POD)-like activity.Secondly,NIR-II induced surface plasmon resonance can induce hot electrons to enhance the catalytic activity of Au–Ag–GOx HTNs,eventually boosting the generation of hydroxyl radicals(•OH).Interestingly,the generated H2O2 and H+can simultaneously induce the degradation of Ag nanoprisms to break the intact triangle nanostructure,thus promoting the excretion of Au–Ag–GOx HTNs to avoid the potential risks of drug metabolism.Overall,the NIR-II driven plasmon-enhanced catalytic mechanism of this bio-breakable nanozyme provides a promising approach for the development of nanozymes in tumor therapy.

关键词： near-infrared(NIR)-II driven plasmon-enhanced catalysis Au-Ag hollow nan otria ngles bio-breakable cascade reaction

数字赋能南京乡村旅游高质量发展的路径与机制研究

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市场周刊 2024年第10期37卷 59-62,169页

作者：王辰刘雅聪王宇乐南京财经大学江苏南京210023

随着数字经济的进一步发展,数字技术赋能乡村旅游产业可以激发新动能,推动实现高质量发展。当前,南京乡村旅游发展进入新节点,但数字经济对其带来的整体赋能效应仍然有限。文章通过构建数字赋能乡村旅游高质量发展的评价指标,基于熵权TO... 详细信息

随着数字经济的进一步发展,数字技术赋能乡村旅游产业可以激发新动能,推动实现高质量发展。当前,南京乡村旅游发展进入新节点,但数字经济对其带来的整体赋能效应仍然有限。文章通过构建数字赋能乡村旅游高质量发展的评价指标,基于熵权TOPSIS模型,试图探索适宜南京市乡村旅游数字化发展的路径,为其高质量发展提供对策。

关键词：数字赋能乡村旅游熵权TOPSIS模型

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管式加热炉甲烷掺氢比对燃烧及NO_(x)排放的影响

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石油化工设备技术 2024年第3期45卷 60-66,I0004页

作者：王文奇高宇乐郭晔媛洛阳瑞昌环境工程有限公司河南洛阳471003

文章主要研究管式加热炉甲烷掺氢比对燃烧及NO_(x)排放的影响,为此基于管式加热炉,分别在1号炉测试圆形燃烧器,在3号炉测试附墙燃烧器。利用fluent中的FGM燃烧模型耦合GRI-Mech 3.0详细反应机理,结合热态实测烟气温度对其燃烧进行数值计... 详细信息

文章主要研究管式加热炉甲烷掺氢比对燃烧及NO_(x)排放的影响,为此基于管式加热炉,分别在1号炉测试圆形燃烧器,在3号炉测试附墙燃烧器。利用fluent中的FGM燃烧模型耦合GRI-Mech 3.0详细反应机理,结合热态实测烟气温度对其燃烧进行数值计算,研究分析管式加热炉甲烷掺氢比对燃烧及NO_(x)排放的影响。甲烷掺氢比控制在0%~60%(体积百分数)。研究结果显示:1)随着掺氢比的提升,1号炉NO_(x)排放量(标准状态,下同)由75 mg/m^(3)上升至100 mg/m^(3),3号炉NO_(x)排放量由63 mg/m^(3)下降至50 mg/m^(3);2)随着掺氢比的提升,温度高于1500℃时,1号炉热斑主要分布在燃烧器喷口之内且面积不断增大,3号炉热斑主要分布在燃烧器喷口之外且面积不断减小;3)在节能减排方面,相对于20%的掺氢比,掺氢比为60%时,1号炉换热效率提升了4.53%,3号炉换热效率提升了0.52%,烟气中二氧化碳减排26%;4)上述结果表明,掺氢提升NO_(x)排放,但炉内烟气内循环却减少NO_(x)排放,燃烧器最终的NO_(x)排放结果受到掺氢和烟气内循环综合效果的影响。

关键词：管式加热炉甲烷掺氢比热斑燃烧试验测量试验验证数值模拟

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基于流固耦合的卡车油箱振动特性研究

噪声与振动控制 2024年第2期44卷 197-201页

作者：胡效东皮永禄刘晓彤王可栋李雨乐山东科技大学机械电子工程学院山东青岛266590 青岛黄海学院智能制造学院山东青岛266555

卡车油箱在使用过程中,存在因振动产生本体及焊缝开裂的问题。针对某400 L卡车柴油油箱,基于流固耦合理论,运用ANSYS软件分析油箱的振动特性。锤击法模态试验和仿真模态分析结果,仿真与试验测得的结构模态参数数据误差最大为13%,仿真的... 详细信息

卡车油箱在使用过程中,存在因振动产生本体及焊缝开裂的问题。针对某400 L卡车柴油油箱,基于流固耦合理论,运用ANSYS软件分析油箱的振动特性。锤击法模态试验和仿真模态分析结果,仿真与试验测得的结构模态参数数据误差最大为13%,仿真的准确性得到验证。油箱结构自由状态下计算得到的前6阶固有频率略大于油箱安装状态下的固有频率,油箱固有频率会随着液体含量的增加而降低。油箱的固有频率在液体量从0到100 L以及300到400 L这两阶段变化明显。油箱充液比低于1/2时,油箱结构的各阶固有频率均高于危险区域的频率,不会产生共振。充液量大于3/4时固有频率接近于30 Hz的标准规定值,存在共振风险。油箱设计时,应优化油箱的结构,使其在充满液量时也能避开30 Hz标准值,更为安全。

关键词：振动与波卡车油箱流固耦合湿模态固有频率