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Dendritic cell migration in inflammation and immunity

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Cellular & Molecular Immunology 2021年第11期18卷 2461-2471页

作者： Juan Liu Xiaomin Zhang yujie cheng Xuetao Cao National Key Laboratory of Medical Immunology&Institute of Immunology Second Military Medical UniversityShanghaiChina Department of Immunology Center for ImmunotherapyInstitute of Basic Medical SciencesChinese Academy of Medical SciencesBeijingChina

Dendritic cells(DCs)are the key link between innate immunity and adaptive immunity and play crucial roles in both the promotion of immune defense and the maintenance of immune *** trafficking of distinct DC subsets across lymphoid and nonlymphoid tissues is essential for DC-dependent activation and regulation of inflammation and *** chemotaxis and migration are triggered by interactions between chemokines and their receptors and regulated by multiple intracellular mechanisms,such as protein modification,epigenetic reprogramming,metabolic remodeling,and cytoskeletal rearrangement,in a tissue-specific *** of DC migration may lead to abnormal positioning or activation of DCs,resulting in an imbalance of immune responses and even immune pathologies,including autoimmune responses,infectious diseases,allergic diseases and *** strategies targeting the migration of distinct DC subsets are being explored for the treatment of inflammatory and infectious diseases and the development of novel DC-based *** this review,we will discuss the migratory routes and immunological consequences of distinct DC subsets,the molecular basis and regulatory mechanisms of migratory signaling in DCs,and the association of DC migration with the pathogenesis of autoimmune and infectious diseases.

关键词： dendritic cells cell migration chemokine receptor CCR7 inflammation autoimmune diseases

Chiral liquid crystals based on pillararene and supramolecular self-assembly-induced chirality amplification

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Science China Chemistry 2024年第10期67卷 3373-3381页

作者： Bicong Liang yujie cheng Xiong Liu Lan Jia Xuehong Wei Qiang Zheng Pi Wang Danyu Xia Xuzhou Yan College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Scientific Instrument Center Shanxi UniversityTaiyuan 030006China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China

Macrocyclic liquid crystals combine the unique property of liquid crystals and excellent supramolecular assembly ability of macrocyclic *** is a significant challenge to make rational use of the advantages of macrocyclic compounds to prepare new macrocyclic ***,a type of macrocycles with rigid pillar-shaped frameworks and easy-tofunctionalize property,are excellent building blocks to fabricate liquid crystal ***,the site-selective modification property of pillararene has been rarely exploited to tailor liquid crystal *** reported pillararene-based liquid crystal systems are almost prepared by per-functionalized ***,we report the regulation of chiral liquid crystal behaviors by different derivatization of *** and thermotropic liquid crystals with different chirality were obtained by self-assembly of pillararene with different numbers of cholesterol *** bridge between thermotropic liquid crystal and lyotropic liquid crystal based on pillararene is *** addition,the chirality of the mesogens can be amplified through supramolecular self-assembly driven by noncovalent *** on the different liquid crystal behaviors,the optical signal of the pillararene-based chiral liquid crystals was used to fabricate an information encryption *** work provides a simple strategy to regulate liquid crystal behaviors via pillararene-based mesogens and realizes information encryption through the combination of different types of liquid crystals.

关键词： chiral liquid crystal pillararene self-assembly cholesterol information encryption

Quasi-continuous synthesis of cobalt single atom catalysts for transfer hydrogenation of quinoline

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Chinese Chemical Letters 2022年第5期33卷 2569-2572页

作者： Liyun Huang Hao Zhang yujie cheng Qingdi Sun Tao Gan Qian He Xiaohui He Hongbing Ji Fine Chemical Industry Research Institute School of ChemistrySun Yat-sen UniversityGuangzhou 510275China Huizhou Research Institute of Sun Yat-sen University Huizhou 516216China School of Chemical Engineering Guangdong University of Petrochemical TechnologyMaoming 525000China School of Environmental and Chemical Engineering Foshan UniversityFoshan 528000China

Improving the transfer hydrogenation of N-heteroarenes is of key importance for various industrial pro-cesses and remains a challenge so *** reported here a microcapsule-pyrolysis strategy to quasi-continuous synthesis S,N co-doped carbon supported Co single atom catalysts(Co/SNC),which was used for transfer hydrogenation of quinoline with formic acid as the hydrogen *** the unique ge-ometric and electronic properties of the Co single atoms,the excellent catalytic activity,selectivity and stability were *** from the quasi-continuous synthesis method,the as-obtained cata-lysts provide a reference for the large-scale preparation of single atom catalysts without amplification *** catalytic performances and quasi-continuous preparation process,demonstrating a new and promising approach to rational design of atomically dispersed catalysts with maximum atomic efficiency in industrial.

关键词： Quasi-continuous synthesis Single atom catalysts Microcapsule Transfer hydrogenation Quinoline

A clusteroluminescent supramolecular polymer network constructed by pillararene and its application in information encryption

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Aggregate

Aggregate 2024年第5期5卷 491-500页

作者： Meiru Zhang yujie cheng Ting Zhang Bicong Liang Xuehong Wei Pi Wang Danyu Xia Xuzhou Yan Scientiﬁc Instrument Center Shanxi UniversityTaiyuanP.R.China College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuanP.R.China School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghaiP.R.China

Clusterization-triggered emissive(CTE)materials have attracted great attention in recent *** regulation of the emission property of materials with CTE property through supramolecular interactions is an excellent strategy for the construction of smartﬂuorescent *** this work,we have pre-pared a regulatable supramolecular polymer network with CTE properties through pillararene-based host-guest *** pillar[5]arene-grafted poly(methyl methacrylate)(PMMA)showed a classic CTE *** adding Brooker’s merocyanine-grafted polymer to the solution of the pillar[5]arene-containing PMMA,the supramolecular polymer network gel formed by the host-guest inter-actions between pillararene and Brooker’s merocyanine *** supramolecular network showed brighterﬂuorescence than the pillar[5]arene-grafted PMMA in the solid *** addition,theﬂuorescence emission of the supramolecular network can be further regulated by pH *** adding an acid,the Brooker’s merocyanine-containing guest polymer was protonated,and the supramolecular net-work changed to a protonated network through host-guest interactions between protonated Brooker’s merocyanine guest and ***,theﬂuores-cence was quenched when the supramolecular network turned into the protonated *** adding a base,the protonated network can convert back to the origi-nal network,along with recovery of theﬂ***,the regulation of theﬂuorescence of the supramolecular polymer materials with CTE was successfully realized by pillararene-based host-guest ***,this tailorableﬂuorescent supramolecular polymer network system was applied as an information encryption material.

关键词： clusterization-triggered emission host-guest interactions pillararene supramolecular polymers

Synthesis of Nitrogen-doped Carbon Supported Cerium Single Atom Catalyst by Ball Milling for Selective Oxidation of Ethylbenzene

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Chemical Research in Chinese Universities 2022年第5期38卷 1258-1262页

作者： ZHANG Xingcong ZHONG Yunzhu CHEN Hongyu cheng yujie SUN Qingdi ZHANG Hao HE Qian ZHANG Ying GUO Guanghui HE Xiaohui JI Hongbing Fine Chemical Industry Research Institute School of ChemistrySun Yat-sen UniversityGuangzhou 510275P.R.China Huizhou Research Institute of Sun Yat-sen University Huizhou 516216P.R.China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516000P.R.China

Through screening Ce precursors and pyrolysis temperatures[Ce(acac)3 as Ce precursors and pyrolysis at 900°C],zeolitic imidazolate framework-8(ZIF-8)derived nitrogen-doped carbon supported cerium single atom catalyst(Ce_(1)/NC)is successfully prepared by ball milling *** Ce_(1)/NC catalyst exhibits exceptional catalytic performance in the selective oxidation of saturated C―H bonds in aromatic compounds,e.g.,91%conversion and 99%selelctivity can be achieved in the oxidation of ethylbenzene to acetophenone under mild reaction conditions.

关键词： Single atom catalyst Ball milling ZIF-8 Ethylbenzene oxidation

Rheological Properties of Five Plant Gums

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American Journal of Analytical Chemistry 2018年第4期9卷 210-223页

作者： Quanquan Miao Huaishi Jiang Lei Gao yujie cheng Jiachao Xu Xiaoting Fu Xin Gao College of Food Science and Engineering Ocean University of China Qingdao China

The rheological properties of five gum solutions (Gum Shiraz, Karaya Gum, Ghatti Gum, Arabic Gum and Gum Tragacanth) have been examined. The five mucilage solutions exhibited non-Newtonian, shear-thinning with thixotropy at higher concentrations (0.5% - 1%, m/v). According to the change of viscosity with increasing temperature, all five gums could be defined as three types: gum tragacanth and gum shiraz have a good temperature stability;karaya gum is affected by temperature obviously;the remaining two gums have a general stability. The viscosity of mucilage solutions (Arabic Gum, Ghatti Gum and Karaya Gum) had an apparent dependence on temperature. The parameter n of Shiraz Gum is the minimum, which means it has the best flow properties. The flow activation energy of karaya gum is 2.683 kcal which is the highest than other gums so that it has a great influence on temperature. The gum solutions’ viscosity had different sensitive degree over tested pH range (pH 2 - 10). Shiraz gum and arabic gum possessed better acid-proof and alkali-proof respectively. The addition of salts (NaCl and CaCl2) led to the reduction of viscosity, which was more sensitive to Ca2+ than to Na+. Both storage modulus G’ and loss modulus G” of all five gums had a dependence on temperature and frequency. These results are potentially useful for the application in the field of food processing.

关键词： Plant Gums Rheological Properties Viscosity Behavior Storage Modulus Loss Modulus

中学生人际适应的特点及其与家庭功能、情绪智力的关系

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中国特殊教育 2011年第2期 65-70,89页

作者：程玉洁邹泓北京师范大学发展心理研究所北京100875

采用青少年人际适应问卷、家庭功能评价量表、中学生情绪智力问卷调查了2332名中学生的人际适应特点,并探讨家庭功能和情绪智力对中学生人际适应的影响。结果发现:(1)中学生的人际适应水平从初一到高二呈逐渐降低的趋势,且女生在亲社会... 详细信息

采用青少年人际适应问卷、家庭功能评价量表、中学生情绪智力问卷调查了2332名中学生的人际适应特点,并探讨家庭功能和情绪智力对中学生人际适应的影响。结果发现:(1)中学生的人际适应水平从初一到高二呈逐渐降低的趋势,且女生在亲社会倾向上的得分显著高于男生;(2)家庭功能显著预测中学生人际适应,家庭功能的相互关系、沟通、父母关注与人际适应的亲社会倾向维度呈显著正相关,家庭冲突、父母控制与亲社会倾向呈显著负相关;相互关系、沟通、父母关注与人际疏离呈显著负相关,家庭冲突、父母控制与人际疏离呈显著正相关;(3)情绪智力在家庭功能和人际适应之间发挥完全中介作用。

关键词：人际适应家庭功能情绪智力中学生

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僵尸企业对正常企业出口产品质量的影响研究

东北大学学报（社会科学版） 2024年第6期26卷 44-54页

作者：綦勇程玉杰杨硕东北大学工商管理学院辽宁沈阳110169

提升出口产品质量是实现经济高质量发展和建设贸易强国的关键。然而,僵尸企业的大量存在引发资源错配,对正常企业的出口产品质量的影响尚未受到关注。以2009—2015年中国上市企业微观数据为样本,实证检验僵尸企业对正常企业出口产品质... 详细信息

提升出口产品质量是实现经济高质量发展和建设贸易强国的关键。然而,僵尸企业的大量存在引发资源错配,对正常企业的出口产品质量的影响尚未受到关注。以2009—2015年中国上市企业微观数据为样本,实证检验僵尸企业对正常企业出口产品质量的影响。结果表明:僵尸企业对正常企业的出口产品质量产生显著的负面影响,结论在一系列稳健性与内生性检验后仍稳健。异质性分析表明,僵尸企业对企业出口产品质量的负面影响在私有企业、未获得政府补贴的企业以及中西部地区企业中更为明显。机制检验发现,僵尸企业引发的资源错配降低了正常企业的劳动生产率和研发创新投入,从而影响了出口产品质量的提升。

关键词：僵尸企业出口产品质量劳动生产率创新投入

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面向飞机电源系统故障诊断的知识图谱构建技术及应用

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航空学报 2022年第8期43卷 40-56页

作者：聂同攀曾继炎程玉杰马梁北京航空航天大学可靠性工程研究所北京100083 航空工业第一飞机设计研究院西安710089 可靠性与环境工程技术国防科技重点实验室北京100083 北京航空航天大学可靠性与系统工程学院北京100083

随科技水平发展,飞机机载设备的电气化程度越来越高,飞机电源系统故障对飞机飞行安全的威胁也不断增大,因此需快速准确地判断其健康状态。常用的基于数据驱动的故障诊断方法无法利用专家知识,且结果可解释性差,为实际使用带来了不便。... 详细信息

随科技水平发展,飞机机载设备的电气化程度越来越高,飞机电源系统故障对飞机飞行安全的威胁也不断增大,因此需快速准确地判断其健康状态。常用的基于数据驱动的故障诊断方法无法利用专家知识,且结果可解释性差,为实际使用带来了不便。知识图谱具备将专家知识等非结构化数据进行规范化存储并用于故障诊断的能力,能实现对非结构化先验知识的利用及故障原因的解释。然而在故障诊断领域,知识图谱技术的应用尚不多见。因此本文提出了一种面向飞机电源系统故障诊断的知识图谱构建及应用技术。首先,利用专家知识构建知识图谱的本体,明确知识图谱中的实体和关系类型;然后,使用BMEO标注的实体抽取语料训练双向长短期记忆网络(LSTM)并利用其从非结构化文本中抽取实体;在此基础上,使用关系标注后的关系抽取预料训练基于注意力机制的双向长短期记忆网络,进而利用训练好的模型进行实体间的关系抽取;最终利用抽取出的实体和关系构建面向飞机电源系统故障诊断的知识图谱。本文以飞机电源系统故障排故手册为原始数据,对提出的知识图谱构建方法进行了案例验证,以准确度和召回率等指标分析了所用方法的实体抽取和关系抽取效果,证明了其有效性。在此基础上,本文基于构建的知识图谱实现了飞机电源系统相关故障的智慧搜索、推荐及智能问答,展示了知识图谱技术在故障诊断领域具备的良好应用前景。

关键词：知识图谱故障诊断飞机电源系统双向长短期记忆网络