检索结果-南通市图书馆

WIP1在口腔鳞状细胞癌中的表达及其与MYLK3的相关性研究

在线全文

学校读者我要写书评

暂无评论

延安大学学报（医学科学版） 2024年第3期22卷 19-23,30页

作者：张羽佳高峰王云静张英英王大维河北医科大学第三医院口腔颌面外科河北石家庄050051 河北医科大学第三医院病理科河北石家庄050051

目的探讨野生型P53诱导的磷酸酶1(Wild-type P53-induced phosphatase1,WIP1)在口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)中的表达及其与肌球蛋白轻链激酶3(myosin light chain kinase 3,MYLK3)的相关性。方法采用免疫组化ABC法检测WIP1及MYLK3在65对OSCC及癌旁正常口腔黏膜中的表达,并通过肿瘤基因组图谱(the Cancer Genome Atlas,TCGA)数据库对WIP1在OSCC中的表达加以验证。分析WIP1的表达与患者年龄、性别、肿瘤分化程度及淋巴结转移等临床病理学指标的关系及其与MYLK3的相关性。结果WIP1在OSCC中的阳性表达率明显高于癌旁正常口腔黏膜中的阳性表达率(47.7%vs 24.6%,P0.05);WIP1与MYLK3在OSCC中的表达呈正相关(r=0.531,P<0.001)。结论WIP1在OSCC的发生、发展、分化及转移过程中可能发挥重要作用,有望成为判断OSCC发生、发展及预测淋巴结转移的新的潜在生物学标志物,其作用机制可能与MYLK3在OSCC中的正协同作用有关。

关键词：口腔鳞状细胞癌野生型P53诱导的磷酸酶1 肌球蛋白轻链激酶3 免疫组织化学生物学标志物

Factors affecting consumer acceptance of electronic cash in China:an empirical study

在线全文

学校读者我要写书评

暂无评论

Financial Innovation 2022年第1期8卷 288-306页

作者： Bo Qu Li Wei yujia zhang Statistics Department National Internet Finance Association of ChinaBeijing 100032China Research Institution The People’s Bank of ChinaBeijing 100032China School of Finance Renmin University of ChinaNo.59 Zhongguancun StreetHaidian Dist.Beijing 100872China China Financial Policy Research Center Renmin University of ChinaNo.59 Zhongguancun StreetHaidian Dist.Beijing 100872China China Insurance Institute Renmin University of ChinaNo.59 Zhongguancun StreetHaidian Dist.Beijing 100872China

This paper proposes and validates a comprehensive model of consumer acceptance in the context of offline e-cash *** modifies the unified theory of acceptance and the use of technology model(UTAUT)with constructs of perceived security,cost of use,and government *** collected from 4428 questionnaires about users’attitudes toward e-cash is used to apply a structural equation model which,in turn,assesses the predictive *** empirical results indicate that perceived security and cost of use are beneficial extensions to the traditional UTAUT model,and intention is a key antecedent to users’actual utilization of *** addition,the demographic moderators are found to have significant effects on the relations among the *** results are useful to e-cash development and significant to the issue of Digital Currency Electronic Payment.

关键词： Electronic cash acceptance UTAUT SEM DCEP

SNR-adaptive deep joint source-channel coding scheme for image semantic transmission with convolutional block attention module

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Journal of China Universities of Posts and Telecommunications 2024年第1期31卷 1-11页

作者： Yang yujia Liu Yiming zhang Wenjia zhang Zhi State Key Laboratory of Networking and Switch Technology Beijing University of Posts and TelecommunicationsBeijing 100876China

With the development of deep learning(DL),joint source-channel coding(JSCC)solutions for end-to-end transmission have gained a lot of *** deep JSCC schemes support dynamically adjusting the rate according to different channel conditions during transmission,enhancing robustness in dynamic wireless ***,most of the existing adaptive JSCC schemes only consider different channel conditions,ignoring the different feature importance in the image processing and *** uniform compression of different features in the image may result in the compromise of critical image details,particularly in low signal-to-noise ratio(SNR)*** address the above issues,in this paper,a dual attention mechanism is introduced and an SNR-adaptive deep JSCC mechanism with a convolutional block attention module(CBAM)is proposed,in which matrix operations are applied to features in spatial and channel dimensions *** proposed solution concatenates the pooling feature with the SNR level and passes it sequentially through the channel attention network and spatial attention network to obtain the importance evaluation *** show that the proposed solution outperforms other baseline schemes in terms of peak SNR(PSNR)and structural similarity(SSIM),particularly in low SNR scenarios or when dealing with complex image content.

关键词： semantic communication joint source-channel coding image transmission

Self-assembled supramolecular immunomagnetic nanoparticles throughπ-πstacking strategy for the enrichment of circulating tumor cells

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2023年第1期10卷 603-613页

作者： Yanchao Mao yujia zhang Yue Yu Nanhang Zhu Xiaoxi Zhou Guohao Li Qiangying Yi Yao Wu National Engineering Research Center for Biomaterials Sichuan UniversityChengduSichuan 610064P.R.China

Owing to their high-specific binding toward targets as well as fast and convenient separation operations,immunomagnetic beads(IMBs)are widely used in the capture and detection of circulating tumor cells(CTCs).To construct the IMBs,surface modifications are generally performed to functionalize the magnetic cores(***_(3)O_(4)nanoparticles),and the employed surface modification strategies normally influence the structure and functions of the prepared IMBs in *** from the existing work,we proposed the use of supramolecular layer-by-layer(LBL)self-assembly strategy to construct the *** general,owing to theπ-πstacking interactions,the polydopamine,graphene oxide and‘molecular glue’γ-oxo-1-pyrenebutyric acid were self-assembled on Fe_(3)O_(4)nanoparticles sequentially,thereby accomplishing the integration of different functional components onto magnetic cores to prepare the self-assembled supramolecular immunomagnetic beads(ASIMBs).The ASIMBs showed high sensitivity,specificity and good biocompatibility to the model CTCs and low nonspecific adsorption to the negative cells(∼93%for MCF-7 cells and 17%for Jurkat cells).Meanwhile,ASIMBs possessed a remarkable potential to screen the rare MCF-7 cells out of large amounts of interfering Jurkat cells with the capture efficiency of 75-100%or out of mouse whole blood with the capture efficiency of 20-90%.The captured cells can be further recultured directly without any more treatment,which showed huge applicability of the ASIMBs for in vitro detection in clinical practices.

关键词： circulating tumor cells magnetic nanoparticles layer-by-layer self-assembly strategy π-π stacking

文化数字化背景下数字博物馆的传播策略研究——基于十大国家一级博物馆的案例分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

北京印刷学院学报 2024年第7期32卷 20-24页

作者：游昕越杨凌雨尹沂鑫张钰佳北京印刷学院北京102600

博物馆是文化数字化的重点建设对象,为解决中国数字博物馆的现存问题,分析了博物馆的现状,探寻在互联网时代数字博物馆文化建设的机遇与挑战,采用案例分析法、调查法等研究方法,基于对中国十大国家一级博物馆的数字博物馆的分析,对中国... 详细信息

博物馆是文化数字化的重点建设对象,为解决中国数字博物馆的现存问题,分析了博物馆的现状,探寻在互联网时代数字博物馆文化建设的机遇与挑战,采用案例分析法、调查法等研究方法,基于对中国十大国家一级博物馆的数字博物馆的分析,对中国博物馆数字化建设现状进行总结,并分析归纳数字博物馆建设带来的传播效果。结果发现,数字博物馆的三维数字化建设在近几年发展较为迅速。而在数字博物的蓬勃发展阶段,仍然存在技术与设备不成熟、展示方式单一、数字资源的版权侵权、资金短缺等问题。数字博物馆在文化传播上具有较大的优势,在数字技术的支持下,数字博物馆可以整合更加多元化的信息,并优化展览的逻辑结构层次,提升文化传播的效率。

关键词：数字博物馆文化传播优化路径

经典名方玉女煎物质基准的薄层鉴别方法学研究

在线全文

学校读者我要写书评

暂无评论

山东化工 2024年第11期53卷 172-174,194页

作者：秦友文李月张雨情刘子垚张羽佳北京春风药业有限公司北京101400

目的:建立经典名方玉女煎物质基准中熟地黄、知母、牛膝的薄层鉴别方法。方法:采用薄层色谱法,以毛蕊花糖苷、熟地黄对照药材以及芒果苷、知母对照药材为对照,建立玉女煎中熟地黄和知母的薄层鉴别方法;以齐墩果酸、牛膝对照药材为对照,... 详细信息

目的:建立经典名方玉女煎物质基准中熟地黄、知母、牛膝的薄层鉴别方法。方法:采用薄层色谱法,以毛蕊花糖苷、熟地黄对照药材以及芒果苷、知母对照药材为对照,建立玉女煎中熟地黄和知母的薄层鉴别方法;以齐墩果酸、牛膝对照药材为对照,建立玉女煎中牛膝的薄层鉴别方法,并对其进行方法学验证。结果:3种物质被很好地分离,现象明显,方法学考察结果良好。结论:该方法操作简便、结果准确,可作为3种物质的鉴别方法,用于玉女煎物质基准的质量控制。

关键词：玉女煎熟地黄知母牛膝薄层色谱

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

局部干法水下激光焊接装置研制及工艺试验

电焊机 2024年第1期54卷 50-54页

作者：张义林张玉佳朱勇辉朱加雷袁军付超中国核动力研究设计院四川成都610213 北京石油化工学院北京102600

针对核电站乏池边角位置的水下修复需求,研制了一套局部干法水下激光焊接装置,可在实现常规水下平焊位置焊接的同时,重点兼顾角焊缝的局部干法水下焊接作业需求。同时,该装置还具备水下焊接位置的照明、焊接环境和焊接过程的实时监控、... 详细信息

针对核电站乏池边角位置的水下修复需求,研制了一套局部干法水下激光焊接装置,可在实现常规水下平焊位置焊接的同时,重点兼顾角焊缝的局部干法水下焊接作业需求。同时,该装置还具备水下焊接位置的照明、焊接环境和焊接过程的实时监控、焊接区域的温湿度监测等功能。采用研制的局部干法水下焊接装置,对核电站乏池常用的304不锈钢材料进行了水下焊接工艺试验,结果表明:水下焊接焊缝的成形良好,水下焊缝的宏观形貌、截面形貌和金相组织与空气环境成形焊缝无显著差异。

关键词：角焊缝激光焊接局部干法装置研制

Field-effect transistor memories based on ferroelectric polymers

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Semiconductors 2017年第11期38卷 1-14页

作者： yujia zhang Haiyang Wang Lei zhang Xiaomeng Chen Yu Guo Huabin Sun Yun Li School of Electronic Science and Engineering National Laboratory of Solid-State Microstructures Collaborative Innovation Center of Advanced Microstructures Nanjing 210093 China

Field-effect transistors based on ferroelectrics have attracted intensive interests, because of their non-volatile data retention, rewritability, and non-destructive read-out. In particular, polymeric materials that possess ferroelectric properties are promising for the fabrications of memory devices with high performance, low cost, and large-area manufacturing, by virtue of their good solubility, low-temperature processability, and good chemical stability. In this review, we discuss the material characteristics of ferroelectric polymers, providing an update on the current development of ferroelectric field-effect transistors（Fe-FETs） in non-volatile memory applications.

关键词： ferroelectric polymers field-effect transistor memories ferroelectricity

A Multi-slack Bus Model for Bi-directional Energy Flow Analysis of Integrated Power-gas Systems

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第5期10卷 2186-2196页

作者： yujia Huang Qiuye Sun Ning zhang Rui Wang College of Information Science and Engineering Northeastern UniversityShenyang 110819China

The bi-directional energy conversion components such as gas-fired generators(GfG)and power-to-gas(P2G)have enhanced the interactions between power and gas *** paper focuses on the steady-state energy flow analysis of an integrated power-gas system(IPGS)with bi-directional energy conversion *** the shortcomings of adjusting active power balance only by single GfG unit and the capacity limitation of slack bus,a multi-slack bus(MSB)model is proposed for integrated power-gas systems,by combining the advantages of bi-directional energy conversion components in adjusting active *** components are modeled as participating units through iterative participation factors solved by the power sensitivity method,which embeds the effect of system *** this basis,the impact of the mixed problem of multi-type gas supply sources(such as hydrogen and methane generated by P2G)on integrated system is considered,and the gas characteristics-specific gravity(SG)and gross calorific value(GCV)are modeled as state variables to obtain a more accurate operational ***,a bi-directional energy flow solver with iterative SG,GCV and participation factors is developed to assess the steady-state equilibrium point of IPGS based on Newton-Raphson *** applicability of proposed methodology is demonstrated by analyzing an integrated IEEE 14-bus power system and a Belgian 20-node gas system.

关键词： Bi-directional energy flow analysis integrated power-gas system(IPGS) multi-slack bus model multi-type gas supply sources