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Pulmonary artery diameter ratio as a prognostic indicator of congenital diaphragmatic hernia

World Journal of Pediatric Surgery 2024年第1期7卷 20-25页

作者： yuichiro Miyake Hiroyuki Koga Shuko Nojiri Shunsuke Yamada Takanori Ochi Go Miyano Geoffrey J Lane Atsuyuki Yamataka Tadaharu Okazaki Department of Pediatric General and Urogenital Surgery Juntendo University School of MedicineBunkyo-kuTokyoJapan Department of Medical Technology Innovation Center Juntendo UniversityBunkyo-ku TokyoJapan Department of Pediatric Surgery Juntendo University Urayasu HospitalUrayasuChibaJapan

Background Following on from an earlier study published in 2008 about left pulmonary artery(LPA)flow measured on serial echocardiography being strongly prognostic in left-sided congenital diaphragmatic hernia(CDH)and the ratio of LPA to right pulmonary artery(RPA)diameters being a simple and reliable indicator for commencing nitric oxide(NO)therapy,the ratio of LPA:RPA diameters(PA ratio orPAR)was hypothesized to possibly reflect cardiopulmonary stresses accompanying CDH better.Methods Subjects with isolated left-sided CDH treated between 2007 and 2020 at a single pediatric surgical center were recruited and classified according to survival.Data obtained retrospectively for subject demographics,clinical course,LPA/RPA diameters,and PAR were compared between survivors and non-survivors.The value of PAR for optimizing the prognostic value of PA diameter data in CDH were analyzed with receiver operating characteristic(ROC)curve analysis.Results Of 65 subjects,there were 54 survivors(82.3%)and 11 non-survivors(17.7%);7 of 11 non-survivors died before surgical repair could be performed.Mean PAR for survivors(0.851±0.152)was significantly higher than for non-survivors(0.672±0.108)(p=0.0003).Mean PAR for non-survivors was not affected by surgical repair.Characteristics of survivors were:LPA≥2 mm(n=52 of 54;mean PAR=0.866±0.146)and RPA≥3mm(n=46 of 54;mean PAR=0.857±0.152).Non-survivors with similar LPA and RPA diameters to survivors had significantly lower mean PAR.ROC curve cut-off for PAR was 0.762.Subjects with high PAR(≥0.762)required high-frequency oscillatory ventilation/NO less than subjects with low PAR(<0.762)(p=0.0244 and p=0.0485,respectively)and subjects with high PAR stabilized significantly earlier than subjects with low PAR(1.71±0.68 days vs 3.20±0.87 days)(p<0.0001).Conclusions PAR would appear to be strongly correlated with clinical outcome in CDH and be useful for planning management of cardiopulmonary instability in CDH.

关键词： hernia congenital diameters

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Relationship between nutritional therapy and beneficial bacteria ratio in severe disease

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Journal of Acute Disease 2024年第1期13卷 26-30页

作者： Kento Nakayama Hiroyuki Koami yuichiro Sakamoto Advanced Emergency Care Center Saga University HospitalSaga 849-0851Japan

Objective:To evaluate relationship between changes in the beneficial bacteria in intensive care unit(ICU)patients and nutritional therapy type.Methods:Ten patients aged≥18 years admitted to the ICU between January and December 2020,were included.Good enteral nutrition was defined as early achievement of target calorie intake through enteral feeding.The ratio of beneficial bacteria at the first and second bowel movements after each patient’s admission was calculated and the patients were classified into the increase or decrease group.Among all patients,five each were in the increase and decrease groups.We investigated patient background,changes in sequential organ failure assessment(SOFA)and acute physiology and chronic health evaluation(APACHE)Ⅱscores,nutritional doses or methods,and clinical outcomes.Results:No relationship was found between changes in the ratio of beneficial bacteria and changes in SOFA/APACHEⅡscores at the time of admission.The rate of good enteral nutrition was significantly higher in the increase group than in the decrease group(4/5 vs.0/5,P=0.01).Conclusions:An increase in beneficial bacteria may be significantly related to the early establishment of enteral nutrition.In the future,accumulating cases may make it possible to establish a new nutritional strategy for critically ill patients from an intestinal microbiota perspective.

关键词： Beneficial bacteria Enteral nutrition Parenteral nutrition Intensive care unit Good enteral nutrition Severe disease Nutritional therapy

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Prediction of return of spontaneous circulation in outof-hospital cardiac arrest with non-shockable initial rhythm using point-of-care testing: a retrospective observational study

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World Journal of Emergency Medicine 2023年第2期14卷 89-95页

作者： Kota Shinada Hiroyuki Koami Ayaka Matsuoka yuichiro Sakamoto Department of Emergency and Critical Care Medicine Faculty of MedicineSaga UniversitySaga CitySaga Prefecture 849-8501Japan Division of Translational Research in Intensive Care Medicine Faculty of MedicineSaga UniversitySaga CitySaga Prefecture 849-8501Japan

BACKGROUND:Out-of-hospital cardiac arrest(OHCA) is a public health concern, and many studies have been conducted on return of spontaneous circulation(ROSC) and its prognostic factors.Rotational thromboelastometry(ROTEM?), a point-of-care testing(POCT) method, has been useful for predicting ROSC in patients with OHCA, but very few studies have focused on patients with non-shockable rhythm. We examined whether the parameters of POCT could predict ROSC in patients with OHCA and accompanying non-shockable rhythm.METHODS:This is a single-center, retrospective observational study. Complete blood count,blood gas, and ROTEM POCT measurements were used. This study included patients with nontraumatic OHCA aged 18 years or older who were transported to the emergency department and evaluated using POCT between January 2013 and December 2021. The patients were divided into the ROSC and non-ROSC groups. Prehospital information and POCT parameters were compared using receiver operating characteristic(ROC) curve analysis, and further logistic regression analysis was performed.RESULTS:Sixty-seven and 135 patients were in the ROSC and non-ROSC groups,respectively. The ROC curves showed a high area under the curve(AUC) for K^(+) of 0.77(95%confidence interval [CI]:0.71–0.83) and EXTEM amplitude 5 min after clotting time(A5) of 0.70(95%CI:0.62–0.77). The odds ratios for ROSC were as follows:female sex 3.67(95%CI:1.67–8.04);K^(+)0.64(95%CI:0.48–0.84);and EXTEM A5 1.03(95%CI:1.01–1.06).CONCLUSION:In OHCA patients with non-shockable rhythm, K^(+) level and the ROTEM parameter EXTEM A5 may be useful in predicting ROSC.

关键词： Rotational thromboelastometry Blood coagulation disorders Extrinsic pathway Potassium

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Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

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Relative importance of tidal flats and artificial habitats for two spoonbill species and related interspecific differences

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Avian Research 2023年第3期14卷 317-325页

作者： Takehiko Shimizu Masayuki Senzaki yuichiro Fujioka Satoquo Seino School of Interdisciplinary Science and Innovation Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan Graduate School of Environmental Science Hokkaido UniversityKita 10-jo Nishi 5-chome Kita-kuSapporoHokkaido060-0810Japan Faculty of Environmental Earth Science Hokkaido UniversityKita 10-jo Nishi 5-chome Kita-kuSapporoHokkaido060-0810Japan Faculty of Social and Cultural Studies Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan Faculty of Engineering Kyushu UniversityMotooka 744Nishi-kuFukuoka819-0395Japan

Artificial/seminatural environments,such as aquacultural ponds,saltpans,and croplands,have recently been acknowledged as important habitats for coastal waterbirds.Although coastal waterbirds tend to use artificial habitats around tidal flats as roosting sites during high-tide,it remains unclear whether the importance of surrounding habitats relative to tidal flats varies among landscape types,seasons,species,or tidal conditions.The Black-faced Spoonbill(Platalea minor)and Eurasian Spoonbill(P.leucorodia)are two closely related sympatric species in East Asia with narrow and wide distribution ranges and habitat requirements,respectively.We therefore expect that both species will use surrounding artificial habitats across seasons at high tides,but Blackfaced Spoonbills will use them less frequently than Eurasian Spoonbills.Here,we address these hypotheses in the Imazu tidal flat and its surrounding environments in southern Japan.We investigated the habitat use and behavioral patterns of both species through route and behavioral surveys during the fall migration and wintering seasons in 2021.We found that both species used surrounding habitats including artificial ones more frequently than the tidal flat regardless of the tidal condition or season,but spoonbills used these habitats more frequently in winter than in autumn.We also found that Eurasian Spoonbills foraged in surrounding artificial habitats more frequently than Black-faced Spoonbills.These results not only demonstrate how coastal waterbirds exploit surrounding habitats relative to tidal flats but also suggest that the importance of surrounding habitats varies among species and seasons.Our study thus emphasizes that valuing and managing surrounding habitats in addition to tidal flats are key to conserving globally declining waterbirds.

关键词： Artificial habitat Behavior Black-faced Spoonbill Eurasian Spoonbill Habitat use Surrounding environment Species distribution model Tidal flat

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Application of appropriate use criteria for percutaneous coronary intervention in Japan

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World Journal of Cardiology 2016年第8期8卷 456-463页

作者： Taku Inohara Shun Kohsaka Ikuko Ueda Takashi Yagi Yohei Numasawa Masahiro Suzuki yuichiro maekawa Keiichi Fukuda Department of Cardiology Hiratsuka City Hos-pital Department of Cardiology Keio University School of Medicine Keio inter--hospital Cardiovascular Studies

The aim of this review was to summarize the concept of appropriate use criteria(AUC) regarding percutaneous coronary intervention(PCI) and document AUC use and impact on clinical practice in Japan, in comparison with its application in the United States. AUC were originally developed to subjectively evaluate the indications and performance of various diagnostic and therapeutic modalities, including revascularization techniques. Over the years, application of AUC has significantly impacted patient selection for PCI in the United States, particularly in non-acute settings. After the broad implementation of AUC in 2009, the rate of inappropriate PCI decreased by half by 2014. The effect was further accentuated by incorporation of financial incentives(e.g., restriction of reimbursement for inappropriate procedures). On the other hand, when the United States-derived AUC were applied to Japanese patients undergoing elective PCI from 2008 to 2013, about one-third were classified as inappropriate, largely due to the perception gap between American and Japanese experts. For example, PCI for low-risk non-left atrial ascending artery lesion was more likely to be classified as appropriate by Japanese standards, and anatomical imaging with coronary computed tomography angiography was used relatively frequently in Japan, but no scenario within the current AUC includes this modality. To extrapolate the current AUC to Japan or any other region outside of the United States, these local discrepancies must be taken into consideration, and scenarios should be revised to reflect contemporary practice. Understanding the concept of AUC as well as its perception gap between different counties will result in the broader implementation of AUC, and lead to the quality improvement of patients' care in the field of coronary intervention.

关键词： Appropriate use criteria Acute coronary syndrome Percutaneous coronary intervention Japan Stable ischemic heart disease

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Median neuropathy after multiple punctures of the forearm for catheterization:A case report

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世界临床病例杂志 2023年第25期11卷 5941-5946页

作者： Tomoaki Suzuki yuichiro Matsui Daisuke Momma Takeshi Endo Norimasa Iwasaki Department of Orthopaedic Surgery Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 060-8638Japan Section for Clinical Education Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Center for Sports Medicine Hokkaido UniversitySapporo 060-8638Japan

BACKGROUND Neuropathy may occur at some sites after catheterization for close examination of cardiac disease.Although the radial artery is considered a relatively uncomplicated site for catheterization,the radial artery and median nerve are in relatively close proximity,with the risk of median nerve injury depending on the angle of puncture.The purpose of this study was to report the outcomes of surgery performed for conservative therapy-resistant median neuropathy following forearm catheterization.CASE SUMMARY A 50-year-old woman experienced palsy from the right thumb to the radial side of the ring finger after catheterization from the radial artery of the right forearm.Paresthesia developed at the same site and a positive tinel-like sign was seen for the median nerve area at the high level of the puncture site.Nerve conduction study showed reduced compound muscle action potentials and loss of sensory nerve action potentials.Symptoms did not improve despite pharmacotherapy and the patient gradually developed flexion restrictions of the index and middle fingers.Median nerve injury and associated flexor tendon adhesion was diagnosed,and the patient was referred for surgery at 3 mo after injury.When the same area was opened,no injury to the median nerve epithelium was obvious,but the area of the positive tinel-like sign was highly adherent to surrounding tissue and to the flexor digitorum superficialis of the index and middle fingers.The surgery was terminated with adequate adhesion release.Rehabilitation was initiated postoperatively,improving neurological symptoms and range of motion of the fingers.Six months after surgery,the patient returned to daily activities without discomfort.CONCLUSION This case provides the appropriate diagnosis and treatment for a suspected peripheral nerve injury.

关键词： Catheterization Median neuropathy Surgical treatment Case report

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An old uterine rupture repaired 2 months postpartum using laparoscopy aided by hysteroscopy: A case report

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Laparoscopic, Endoscopic and Robotic Surgery 2022年第4期5卷 153-157页

作者： yuichiro Kizaki Kouki Samejima Shigetaka Matsunaga Tomonori Nagai Yasushi Takai Department of Obstetrics and Gynecology Saitama Medical CenterSaitama Medical UniversitySaitama Ken 350-8550Japan

With an incidence of 0.005%,unscarred uterine rupture is extremely rare.It is difficult to diagnose uterine rupture because of the absence of characteristic clinical symptoms.Here,we report a rare case of a 31-year-old woman with a uterine rupture that was accurately diagnosed and repaired by laparoscopy and hysteroscopy on postpartum day 69.The patient recovered uneventfully and was discharged on postoperative day 4.Three months after surgery,pelvic magnetic resonance imaging was performed,which confirmed wound repair.In women with a stable condition,laparoscopy with hysteroscopy could be an alternative choice for the diagnosis and treatment of suspected uterine rupture;however,more substantial studies are needed to confirm this surgical approach.

关键词： Hysteroscopy Laparoscopic surgery Uterine rupture Postpartum hemorrhage Uterine preservation

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IDENTIFICATION OF STIFFNESS COEFFICIENTS OF LAMINATED COMPOSITE PLATES

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中国有色金属学会会刊：英文版 1997年第3期7卷 46-50页

作者： Wang, XC Shen, XP yuichiro, M Xu, BY N CHINA UNIV TECHNOL BEIJING 100041PEOPLES R CHINA TSING HUA UNIV DEPT MECH ENGNBEIJING 100084PEOPLES R CHINA IBARAKI UNIV DEPT ENGNHITACHIIBARAKI 316JAPAN

ＩＤＥＮＴＩＦＩＣＡＴＩＯＮＯＦＳＴＩＦＦＮＥＳＳＣＯＥＦＦＩＣＩＥＮＴＳＯＦＬＡＭＩＮＡＴＥＤＣＯＭＰＯＳＩＴＥＰＬＡＴＥＳ①ＷａｎｇＸｉａｏｃｈｕｎ，ＳｈｅｎＸｉｎｐｕ，ＭａｓｕｄａＹｕｉｃｈｉｒｏ，ＸｕＢｉｎｇ... 详细信息

ＩＤＥＮＴＩＦＩＣＡＴＩＯＮＯＦＳＴＩＦＦＮＥＳＳＣＯＥＦＦＩＣＩＥＮＴＳＯＦＬＡＭＩＮＡＴＥＤＣＯＭＰＯＳＩＴＥＰＬＡＴＥＳ①ＷａｎｇＸｉａｏｃｈｕｎ，ＳｈｅｎＸｉｎｐｕ，ＭａｓｕｄａＹｕｉｃｈｉｒｏ，ＸｕＢｉｎｇｙｅＮｏｒｔｈＣｈｉｎａＵｎｉｖｅ...

关键词： inverse analysis composite laminated plate stiffness coefficient

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Investigation of Surge Behavior in a Micro Centrifugal Compressor

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Journal of Thermal Science 2006年第2期15卷 97-102页

作者： Shimpei MIZUKI yuichiro ASAGA Yushi ONO Hoshio TSUJITA Department of Mechanical Engineering Hosei University 3-7-2Kajino-choKoganei-shiTokyo Mitsubishi Heavy Industries Ltd. 1-1 Akunoura-machi Nagasaki-shi Nagasaki Department of Mechanical Engineering Hosei University 3-7-2 Kajino-cho Koganei-shi Tokyo

这份报纸报导巨浪的试验性、理论的学习发生在原型一台极端微离心的压缩机。作为第一步， 10 次缩放有 40 公里的一台极端微离心的压缩机的模型外部直径被设计并且生产。为有 B 参数的几不同价值的巨浪的短暂行为的详细试验性的调查被... 详细信息

这份报纸报导巨浪的试验性、理论的学习发生在原型一台极端微离心的压缩机。作为第一步， 10 次缩放有 40 公里的一台极端微离心的压缩机的模型外部直径被设计并且生产。为有 B 参数的几不同价值的巨浪的短暂行为的详细试验性的调查被执行。试验性的结果在巨浪期间与非线性的 lumped 参数理论获得以便为微离心的压缩机验证理论巨浪模型的有效性的那些相比。作为结果，巨浪的相当不同的行为在实验并且在分析为 B 的不同价值出现了。关键词微离心的压缩机 - 澎湃 - lumped 参数模型 CLC 数字 TK474.

关键词：微离心压缩机汹涌集中参量模型外直径

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