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浙江树人大学学报（自然科学版） 2018年第4期18卷 39-44页

作者：胡李彬阮煜晖周晚晴周昊浙江树人大学浙江杭州310015

对典型的二维平行束CT系统的工作原理进行分析,运用数据可视化处理,几何求解法确定各探测器单元之间的距离及CT系统旋转中心的位置,通过X射线的可逆性采用优化模型确定X射线的180个方向;针对未知介质的信息,通过Radon变换、滤波反投影... 详细信息

对典型的二维平行束CT系统的工作原理进行分析,运用数据可视化处理,几何求解法确定各探测器单元之间的距离及CT系统旋转中心的位置,通过X射线的可逆性采用优化模型确定X射线的180个方向;针对未知介质的信息,通过Radon变换、滤波反投影等方法进行参数标定及图像重建,解决吸收率问题.

关键词： CT系统参数标定图像重建 Radon变换

Advances in extracellular vesicle functionalization strategies for tissue regeneration

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Bioactive Materials 2023年第7期25卷 500-526页

作者： Dandan Zheng Huitong ruan Wei Chen yuhui Zhang Wenguo Cui Hao Chen Hongxing Shen Department of Spine Surgery Renji HospitalShanghai JiaoTong University School of Medicine160 Pujian RoadShanghai200127PR China Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University School of Medicine197 Ruijin 2nd RoadShanghai200025China

Extracellular vesicles(EVs)are nano-scale vesicles derived by cell secretion with unique advantages such as promoting cell proliferation,anti-inflammation,promoting blood vessels and regulating cell differentiation,which benefit their wide applications in regenerative ***,the in vivo therapeutic effect of EVs still greatly restricted by several obstacles,including the off-targetability,rapid blood clearance,and undesired *** address these issues,biomedical engineering techniques are vastly *** review summarizes different strategies to enhance EV functions from the perspective of drug loading,modification,and combination of biomaterials,and emphatically introduces the latest developments of functionalized EV-loaded biomaterials in different diseases,including cardio-vascular system diseases,osteochondral disorders,wound healing,nerve *** and future directions of EVs are also discussed.

关键词： Extracellular vesicle Regenerative medicine Biomaterials Modification Drug delivery

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不同培养基对石仙桃种子萌发的影响

农业工程 2019年第3期9卷 107-111页

作者：吴宇函俞涵曦李静韩晓文阮育慧何碧珠福建农林大学园艺学院福建福州350002 兰科植物保护与利用国家林业与草原局重点实验室福建福州350002

石仙桃为治疗头痛药品的主要材料来源,针对其种子萌发的研究可为制药产业发展提供技术支撑。现以成熟度为150 d优质石仙桃荚果为外植体,探讨添加不同浓度生长素、激素和附加物建立再生体系对石仙桃种子萌发、生长的影响。结果表明,石仙... 详细信息

石仙桃为治疗头痛药品的主要材料来源,针对其种子萌发的研究可为制药产业发展提供技术支撑。现以成熟度为150 d优质石仙桃荚果为外植体,探讨添加不同浓度生长素、激素和附加物建立再生体系对石仙桃种子萌发、生长的影响。结果表明,石仙桃种子萌发最适培养基为MS+6-BA 1. 0 mgL+NAA 0. 1 mgL+KT 0. 5 mgL+蛋白胨1 gL;原球茎诱导增殖的最适培养基为MS+6-BA 1. 0 mgL+KT 0. 5 mgL+NAA 0. 5 mgL+蛋白胨1 gL;假鳞茎诱导的最适培养基为12MS+蛋白胨1. 5 gL+香蕉泥40. 0 gL+土豆泥40. 0 gL+花宝1号1. 0 gL。

关键词：石仙桃种子组织培养

The First OCCCO Pentadentate Chelates:Osmium Mediated Stepwise Oxidations of Terminal Alkynes by Pyridine N-Oxide

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Chinese Journal of Chemistry 2020年第11期38卷 1273-1279页

作者： Jianfeng Lin Qiannan Xu Xinlei Lin yuhui Hua Dafa Chen Yonghong ruan Hong Zhang Haiping Xia College of Chemistry and Chemical Engineering Xiamen UniversityXiamenFujian 361005China Shenzhen Grubbs Institute Department of ChemistryGuangdong Provincial Key Laboratory of CatalysisSouthern University of Science and TechnologyShenzhenGuangdong 518055China

of main observation and conclusion Oxygen atom transfer reactions between alkynes and heteroarene N-oxides are currently mediated by transition metal,such as gold,ruthenium or rhodium,but they have never been catalyzed by ***,we report stepwise oxidations of terminal alkynes mediated by an osmium carbolong complex,using pyridine N-oxide as the oxidant,yielding novel aldehyde-or carboxylic acid-coordinated osmapentalyne derivatives *** mechanism was illustrated by density functional theory calculations,providing a new route for oxygen atom transfer between heteroarene N-oxides and alkynes.

关键词： oxides yielding conclusion

Optimization of the Plugging Agent Dosage for High Temperature Salt Profile Control in Heavy Oil Reservoirs

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Fluid Dynamics & Materials Processing 2023年第2期19卷 421-436页

作者： Jiayu ruan Mingjing Lu Wei Zhang Yuxi Zhang yuhui Zhou Jie Gong Fan Wang Yuanxiao Guan School of Petroleum Engineering Yangtze UniversityWuhan430000China Petroleum Engineering Technology Research Institute of Shengli Oilfield SINOPECDongying257067China Postdoctoral Scientific Research Working Station of Shengli Oilfield SINOPECDongying257067China Petro China Changqing Oilfield Branch No.1 Gas Production Plant Yan’an716000China

After steam discharge in heavy oil reservoirs,the distribution of temperature,pressure,and permeability in different wells becomes *** channels can easily be produced,which affect the sweep efficiency of the oil *** studies have shown that the salting-out plugging method can effectively block these channels in high-temperature reservoirs,improve the suction profile,and increase oil *** the present study,the optimal dosage of the plugging agent is determined taking into account connection transmissibility and inter-well *** with the connectivity model,a water flooding simulation model is ***,a non-gradient stochastic disturbance algorithm is used to obtain the optimal plugging agent dosage,which provides the basis for the high-temperature salting-out plugging agent adjustment in the field.

关键词： Heavy oil salting out profile control high temperature plugging agent dosage optimization numerical simulation connectivity model

Tailoring lithium intercalation pathway in 2D van der Waals heterostructure for high-speed edge-contacted floating-gate transistor and artificial synapses

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InfoMat 2024年第10期6卷 53-64页

作者： Jun Yu Jiawei Fu Hongcheng ruan Han Wang Yimeng Yu Jinpeng Wang yuhui He Jinsong Wu Fuwei Zhuge Ying Ma Tianyou Zhai State Key Laboratory of Materials Processing and Die and Mould Technology School of Material Science and EngineeringHuazhong University of Science and Technology(HUST)Wuhanthe People's Republic of China Hubei Yangtze Memory Laboratory School of Integrated CircuitsHuazhong University of Science and Technology(HUST)Wuhanthe People's Republic of China School of Information Engineering Zhongnan University of Economics and LawWuhanthe People's Republic of China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Nanostructure Research CenterWuhan University of TechnologyWuhanthe People's Republic of China Optics Valley Laboratory Hubeithe People's Republic of China

Local phase transition in transition metal dichalcogenides (TMDCs) by lithiumintercalation enables the fabrication of high-quality contact interfaces in twodimensional(2D) electronic devices. However, controlling the intercalation oflithium is hitherto challenging in vertically stacked van der Waalsheterostructures (vdWHs) due to the random diffusion of lithium ions in thehetero-interface, which hinders their application for contact engineering of 2DvdWHs devices. Herein, a strategy to restrict the lithium intercalation pathwayin vdWHs is developed by using surface-permeation assisted intercalationwhile sealing all edges, based on which a high-performance edge-contact MoS_(2)vdWHs floating-gate transistor is demonstrated. Our method avoids intercalationfrom edges that are prone to be random but intentionally promotes lithiumintercalation from the top surface. The derived MoS_(2) floating-gatetransistor exhibits improved interface quality and significantly reduced subthresholdswing (SS) from >600 to 100 mV dec^(–1). In addition, ultrafast program/erase performance together with well-distinguished 32 memory statesare demonstrated, making it a promising candidate for low-power artificialsynapses. The study on controlling the lithium intercalation pathways in 2DvdWHs offers a viable route toward high-performance 2D electronics for memoryand neuromorphic computing purposes.

关键词： 2D vdW heterostructure high-speed floating-gate transistor interlayer lithium intercalation engineering phase-engineered contact

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一种基于语义推理的网络社区发现模型

西南大学学报（自然科学版） 2022年第9期44卷 178-186页

作者：任薇阮淇昱韩孟凯邱玉辉西南大学计算机与信息科学学院软件学院重庆400715 西南大学人工智能学院重庆400715

网络社区作为新的资源发布和共享方式,其形成模式、发现方式等是网络发展研究热点之一.由于聚类的随机性以及现有划分算法对个体和链接属性信息的语义利用不充分,社会网络的社区不能得到准确的分类.本文提出基于语义推理的网络社区发现... 详细信息

网络社区作为新的资源发布和共享方式,其形成模式、发现方式等是网络发展研究热点之一.由于聚类的随机性以及现有划分算法对个体和链接属性信息的语义利用不充分,社会网络的社区不能得到准确的分类.本文提出基于语义推理的网络社区发现模型,通过节点关系的拓扑结构和节点间的语义联系,抽取多层语义进行搜索并进行社区发现.在ego-Facebook数据集上的实验结果表明,当社区大小增长到1000以后,本算法更加稳定,更适用于节点包含丰富的语义且结构稀疏的网络.

关键词：社区发现语义网络语义链多层模型知识图谱

陀螺电机轴承健康评估隐马尔可夫模型适应性设计

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传感技术学报 2023年第9期36卷 1417-1425页

作者：蔡曜司玉辉王玉琢武展付雪阮芳西安航天精密机电研究所陕西西安710100

陀螺电机的轴承一般采用小体积、高精度的角接触球轴承,其健康状况无法通过外观检查、计量等方法检测,故障具有隐蔽性、潜伏性,当故障发生时,将直接影响陀螺的精度及寿命,故需提前对潜在故障进行识别。基于电机定子电流评估的基本原理,... 详细信息

陀螺电机的轴承一般采用小体积、高精度的角接触球轴承,其健康状况无法通过外观检查、计量等方法检测,故障具有隐蔽性、潜伏性,当故障发生时,将直接影响陀螺的精度及寿命,故需提前对潜在故障进行识别。基于电机定子电流评估的基本原理,选取若干定子电流特征参数用于故障诊断;基于隐马尔可夫模型(HMM)的基本原理,对其进行适应性设计,根据特征参数的特点,提出局部、全局线性归一化方案,并设计适用于多特征参数的模型参数求解算法、轴承健康评估算法。实例验证表明,通过对HMM的适应性设计,健康轴承、故障轴承对应HMM的模型参数正确收敛,健康评估模型成功建立;使用该模型对已知健康、故障的6块电机轴承进行健康评估,可迅速、准确获得评估结果,准确率为100%。

关键词：轴承健康评估隐马尔可夫模型定子电流评估法陀螺电机挠性陀螺

噬菌体vB_SauM_RS对乳源金黄色葡萄球菌生物被膜的清除作用

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食品科学 2021年第1期42卷 52-58页

作者：阮红日王宇辉徐若洋陈立靳育琦王建发宋军郑家三黑龙江八一农垦大学动物科技学院黑龙江大庆163319 黑龙江省牛病防制重点实验室黑龙江大庆163319

目的:以金黄色葡萄球菌为宿主菌,分离裂解性噬菌体vB_SauM_RS,测定其生物学特性,并探究其在两种牛奶中的抑菌效果及对生物被膜的清除作用。方法:将噬菌体与金黄色葡萄球菌以1∶100的比例(菌体数量比)分别接种于脱脂牛奶和全脂牛奶中,分... 详细信息

目的:以金黄色葡萄球菌为宿主菌,分离裂解性噬菌体vB_SauM_RS,测定其生物学特性,并探究其在两种牛奶中的抑菌效果及对生物被膜的清除作用。方法:将噬菌体与金黄色葡萄球菌以1∶100的比例(菌体数量比)分别接种于脱脂牛奶和全脂牛奶中,分别在4℃和25℃环境下处理,测定不同时间脱脂牛奶和全脂牛奶中细菌浓度和噬菌体效价,分析噬菌体在两种牛奶中的抑菌效果;之后通过结晶紫染色、平板计数法和双层平板法测定经噬菌体处理后不同时间膜内细菌浓度和噬菌体效价,分析vB_SauM_RS对不同材料表面生物被膜的清除效果,并通过荧光显微镜观察生物被膜清除前后膜内细菌数量的变化。结果:vB_SauM_RS形成的噬菌斑清晰透亮、外有晕环;透射电子显微镜观察其属于肌尾噬菌体科;最佳感染复数为0.01、潜伏期为20 min、平均裂解量为39 PFU/cell,其在20~50℃和pH 4.0~11.0条件下稳定,具有高效的裂解效率;vB_SauM_RS在牛奶中抑菌作用明显,与对照组相比,在低温(4℃)条件下24 h使脱脂牛奶和全脂牛奶中细菌浓度分别下降1.079(lg(CFU/mL))和1.021(lg(CFU/mL)),在室温(25℃)条件下24 h使脱脂牛奶和全脂牛奶中细菌浓度分别下降5.418(l g(C F U/m L))和5.740(lg(CFU/mL));通过平板计数法和荧光显微镜观察显示vB_SauM_RS对生物被膜内细菌的清除效果明显,对不同材料表面生物被膜均有良好的清除效果。结论:vB_SauM_RS不仅对牛奶中金黄色葡萄球菌有良好的裂解效果,对生物被膜也有很好的清除效果,具有作为金黄色葡萄球菌生物抗菌剂的应用潜力。

关键词：裂解性噬菌体金黄色葡萄球菌生物学特性牛奶生物被膜