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China Ocean Engineering 2024年第2期38卷 297-312页

作者： ZHANG yi chen yue YUN Lai LIANG Xu Ocean College Zhejiang UniversityZhoushan 316000China Hainan Institute Zhejiang UniversitySanya 572000China

This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of *** cuttlebone suffers uniaxial external compression,while underwater cylindrical shells are in a biaxial compressive stress *** suit the biaxial compressive stress state,a novel bidirectional corrugated sandwich structure is proposed to improve the bearing capacity of cylindrical *** static and buckling analysis for the sandwich shell and the unstiffened cylindrical shell with the same volume-weight ratio are studied by numerical *** is indicated that the proposed sandwich shell can effectively reduce the ratio between circumferential and axial stress from 2 to 1.25 and improve the critical buckling load by about 1.63 *** simulation shows that optimizing and adjusting the structural parameters could significantly improve the advantage of the sandwich ***,the hydrostatic pressure tests for shell models fabricated by 3D printing are carried *** to the experimental results,the overall failure position of the sandwich shell is at the center part of the sandwich *** has been found the average critical load of the proposed sandwich shell models exceeds two times that of the unstiffened shell ***,the proposed bio-inspired bidirectional corrugated sandwich structure can significantly enhance the pressure resistance capability of cylindrical shells.

关键词： bio-inspiration bidirectional corrugation sandwich shell external pressure buckling

Exercise-induced adaptation of neurons in the vertebrate locomotor system

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Journal of Sport and Health Science 2024年第2期13卷 160-171页

作者： yue Dai yi cheng Renkai Ge Ke chen Liming Yang Key Lab of Adolescent Health Assessment and Exercise Intervention of Ministry of Education College of Physical Education and Health CareEast China Normal UniversityShanghai 200241China Shanghai Key Laboratory of Multidimensional Information Processing School of Communication and Electronic EngineeringEast China Normal UniversityShanghai 200241China School of Physical Education and Health Care East China Jiaotong UniversityNanchang 330013China Key Laboratory of High Confidence Software Technologies of Ministry of Education School of Computer SciencePeking UniversityBeijing 100871China

Vertebrate neurons are highly dynamic cells that undergo several alterations in their functioning and physiologies in adaptation to various external *** particular,how these neurons respond to physical exercise has long been an area of active *** of the vertebrate locomotor system’s adaptability suggest multiple mechanisms are involved in the regulation of neuronal activity and properties during *** this brief review,we highlight recent results and insights from the field with a focus on the following mechanisms:(a)alterations in neuronal excitability during acute exercise;(b)alterations in neuronal excitability after chronic exercise;(c)exercise-induced changes in neuronal membrane properties via modulation of ion channel activity;(d)exercise-enhanced dendritic plasticity;and(e)exercise-induced alterations in neuronal gene expression and protein *** hope is to update the community with a cellular and molecular understanding of the recent mechanisms underlying the adaptability of the vertebrate locomotor system in response to both acute and chronic physical exercise.

关键词： Dendritic plasticity Excitability Exercise Ion channel modulation Neuron adaptation

Vegetative Storage Protein with Trypsin Inhibitor Activity Occurs in Sapindus mukorassi,a Sapindaceae Deciduous Tree

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Journal of Integrative Plant Biology 2009年第4期51卷 352-359页

作者： Shi-Biao Liu Xu-Chu Wang Min-Jing Shi yue-yi chen Zheng-Hai Hu Wei-Min Tian Institute of Ecology Jishou University Jishou 416000 China Key Laboratory of Rubber Biology Rubber Research Institute Chinese Academy of Tropical Agricultural Sciences Danzhou 571737 China Institute of Botany Northwest University Xi'an 710069 China

A vegetative storage protein （VSP） with trypsin inhibitor activity in a deciduous tree, Sapindus mukorassi, was characterized by means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western-blot, immuno-histochemical localization, light- and electro-microscopy, together with analysis of proteinase inhibitor activity of the purified VSP in vitro. There were two proteins with molecular masses of about 23 and 27 kDa in a relatively high content in the bark tissues of terminal branches of S. mukorassi in leafless periods. The proteins decreased markedly during young shoot development, indicating their role in seasonal nitrogen storage. Immuno-histochemical localization with the polyclonal antibodies raised against the 23 kDa protein demonstrated that the 23 kDa protein was the major component of protein inclusions in protein-storing cells. The protein inclusions were identified by protein-specific staining and should correspond to the electron-dense materials in different forms in the vacuoles of phloem parenchyma cells and phloem ray parenchyma cells under an electron microscope. So, the 23 kDa protein was a typical VSP in S. mukorassi. The 23 and 27 kDa proteins shared no immuno-relatedness, whereas the 23 kDa protein was immuno-related with the 22 kDa VSP in lychee and possessed trypsin inhibitor activity. The 23 kDa protein may confer dual functions： nitrogen storage and defense.

关键词： annual growth cycle Chinese soapberry immuno-localization seasonal nitrogen storage trypsin inhibitor.

Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways

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Food Science and Human Wellness 2024年第1期13卷 115-123页

作者： yue Yu Haibin Zhu Mingyue Shen Qiang Yu yi chen Shiru Mo Jianhua Xie State Key Laboratory of Food Science and Technology Nanchang UniversityNanchang 330047China International Institute of Food Innovation Nanchang UniversityNanchang 330200China

The biological activity of plant polysaccharides can be enhanced by sulfated *** this study,the immunomodulatory effect of sulfated Cyclocarya paliurus polysaccharides(SCP3)on macrophages RAW264.7 and its potential molecular mechanism were *** showed that SCP3 at 25-100μg/m L increased viability and improved phagocytosis of RAW264.7 ***,SCP3 could activate mitogen-activated protein kinase(MAPK)and nuclear factor kappa B(NF-κB)signaling pathways,which increased the phosphorylation of Erk1/2,JNK,p38 and NF-κB p65,promoting secretion of cytokines tumor necrosis factorα(TNF-α),interleukin 6(IL-6)and nitric oxide(NO)as well as the production of reactive oxygen species(ROS).In addition,Toll-like receptor 4(TLR4)receptor inhibitors were able to block the production of NO and TNF-αby SCP3-stimulated *** on Western blot analysis and validation using specific inhibitors against MAPK and NF-κB signaling pathways,the results demonstrated that SCP3 induced macrophages activation and enhanced TNF-αand NO production via TLR4-mediated MAPK and NF-κB *** summary,SCP3 has significant immunomodulatory *** underlying molecular mechanism was that SCP3 activates macrophages via TLR4 receptors to promote ROS production,which in turn activates the downstream MAPK/NF-κB signaling pathway and then increases the secretion levels of cytokines and NO.

关键词： Cyclocarya paliurus Sulfated polysaccharides Macrophages Immunomodulatory Mechanism

Navigating the safe operation of high-voltage cathodes:Challenges and strategies

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Nano Research 2024年第10期17卷 8694-8705页

作者： yue Sun Changjian Zuo yi-Chun Lu Electrochemical Energy and Interfaces Laboratory Department of Mechanical and Automation EngineeringThe Chinese University of Hong KongHong Kong 999077China

Lithium-ion batteries play a crucial role in storing energy for renewable sources and electric vehicles,yet face challenges related to insufficient energy *** the working-voltage of cathodes is promising to boost the energy density of batteries by increasing both the output voltage and capacity of cathode,which however could compromise life cycle and *** review provides a comprehensive summary of essential factors governing pathways of cathode-induced thermal runaway,including electrolyte decomposition,phase transitions,and crosstalk-induced *** and electrolyte modifications aimed at mitigating parasitic reactions and preventing crosstalk were also *** review concludes with insights into the future application of these strategies,providing a comprehensive perspective on the realization of high-energy and safe batteries.

关键词： battery safety high-voltage cathode lithium-ion battery thermal runaway

Salmonella Grumpensis Causing Diarrhea in Children—Shanghai Municipality,China,2023

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China CDC weekly 2024年第18期6卷 396-400,I0006,I0007页

作者： yue Liu Xuebin Xu Wenqin Wang Wenjia Xiao yi Hu Xin chen Min chen Shanghai Municipal Center for Disease Control and Prevention ShanghaiChina Pudong New Area Center for Disease Control and Prevention ShanghaiChina Department of Epidemiology Key Laboratory of Public Health Safety of Ministry of EducationSchool of Public HealthFudan UniversityShanghaiChina

Summary What is already known about this topic?Foodborne diseases are a growing public health concern with a notable disease burden in *** is added by this report?Two children with diarrhea visited a healthcare facility within 24 hours on August 1 and 2,*** Grumpensis was detected in their stool samples by the public health *** genome sequencing(WGS)analysis revealed characteristics typical of outbreak *** the origin of the outbreak was unknown,the possibility of a hidden shared infection was deemed feasible.

关键词： diarrhea diseases Whole

Texture and Se vacancy optimization induces high thermoelectric performance in Bi_(2)Se_(3) flexible thin films

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Rare Metals 2024年第6期43卷 2796-2804页

作者： Dong-Wei Ao Wei-Di Liu yue-Xing chen Fan Ma yi-Jie Gu Zhuang-Hao Zheng School of Machinery and Automation Weifang UniversityWeifang 261061China Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbane 4072Australia Shenzhen Key Laboratory of Advanced Thin Films and Applications Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen518060China School of Materials Science and Engineering Inner Mongolia University of TechnologyHohhot 010051China

Bi_(2)Se_(3)-based flexible thin film with high thermoelectric performance is promising for the waste heat recovery *** this work,a novel post-selenization method is employed to prepare n-type Bi_(2)Se_(3)flexible thin films with highly textured *** strengthened texture and Se vacancy optimization can be simultaneously achieved by optimizing the selenization *** highly oriented texture leads to the increased carrier mobility and results in a high electric conductivity of~290.47 S·cm^(-1)at 623 ***,a high Seebeck coefficient(>110μW·K-1)is obtained due to the reduced carrier concentration,induced by optimizing vacancy ***,a high power factor of 3.49μW·cm^(-1)·K^(-2)at 623 K has been achieved in asprepared highly-bendable Bi_(2)Se_(3)flexible thin films selenized at 783 *** study introduces an effective post-selenization method to tune the texture structure and vacancies of Bi_(2)Se_(3)flexible thin films,and correspondingly achieves high thermoelectric performance.

关键词： Thermoelectric Bi_(2)Se_(3) Flexible thin film Post-selenization

Ultrahigh thermoelectric properties of p‐type Bi_(x)Sb_(2−x)Te_(3)thin films with exceptional flexibility for wearable energy harvesting

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Carbon Energy 2024年第8期6卷 273-284页

作者： Zhuang‐Hao Zheng yi‐Ming Zhong yi‐Liu Li Mohammad Nisar Adil Mansoor Fu Li Shuo chen Guang‐Xing Liang Ping Fan Dongyan Xu Meng Wei yue‐Xing chen Shenzhen Key Laboratory of Advanced Thin Films and Applications Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhenChina Department of Mechanical and Automation Engineering The Chinese University of Hong KongSha TinChina

Use of a flexible thermoelectric source is a feasible approach to realizing selfpowered wearable electronics and the Internet of *** thin films are promising candidates for fabricating flexible power supply,but obtaining highthermoelectric‐performance thin films remains a big *** the present work,a p‐type Bi_(x)Sb_(2−x)Te_(3)thin film is designed with a high figure of merit of 1.11 at 393 K and exceptional flexibility(less than 5%increase in resistance after 1000 cycles of bending at a radius of∼5 mm).The favorable comprehensive performance of the Bi_(x)Sb_(2−x)Te_(3)flexible thin film is due to its excellent crystallinity,optimized carrier concentration,and low elastic modulus,which have been verified by experiments and theoretical ***,a flexible device is fabricated using the prepared p‐type Bi_(x)Sb_(2−x)Te_(3)and n‐type Ag_(2)Se thin ***,an outstanding power density of∼1028μWcm^(−2)is achieved at a temperature difference of 25 *** work extends a novel concept to the fabrication of highperformance flexible thin films and devices for wearable energy harvesting.

关键词： Bi_(x)Sb_(2−x)Te_(3) electrical transport properties flexibility thermoelectric

Azocalixarenes: a scaffold of universal excipients with high efficiency

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Science China Chemistry 2024年第5期67卷 1697-1706页

作者： Yu-Xin yue yi-Lin Lin Meng-Meng chen Han-Wen Tian Rong Ma Ze-Han Wang Fang-Yuan chen Yu-chen Pan Dong-Sheng Guo College of Chemistry State Key Laboratory of Elemento-Organic ChemistryKey Laboratory of Functional Polymer Materials(Ministry of Education)Frontiers Science Center for New Organic MatterCollaborative Innovation Center of Chemical Science and Engineering(Tianjin)Nankai UniversityTianjin 300071China

Excipients are important components of pharmaceutical preparations that affect their quality, safety, and efficacy. Macrocyclic receptors are a family of supramolecular excipients with several advantages, including molecular-level protection, small sizes,fast kinetics of host-guest recognition, and modular construction. With the continuous advances in the medical field, personalized and precision medicine requires the development of excipients with low dosages, integrated modifying effects, universality,and controlled release. To meet these requirements, we have developed a new family of macrocyclic excipients based on calixarenes by integrating their covalent(broad chemical design space) and noncovalent(wide range of substrates) ***, azocalixarenes(Azo CAs) were designed, showing high binding affinities to a broad spectrum of active pharmaceutical ingredients(APIs), selectivity to interferents, and responsiveness to hypoxic microenvironments. Due to their highly efficient and controllable recognition, Azo CAs serve as low-dose excipients for 30 APIs. Molecular encapsulation by Azo CAs results in the integrated modification of the physicochemical properties of APIs, including solubility, stability, bioavailability,and biocompatibility. Moreover, Azo CAs can be reduced by azoreductases overexpressed in hypoxic microenvironments,leading to the controlled release of APIs. Collectively, Azo CA excipients have broad application prospects for a series of diseases such as enteritis, arthritis, stroke, cancer, bacterial infection and kidney injury, with diverse therapeutic modalities,including chemotherapy, photodynamic therapy, photothermal therapy, immunotherapy, boron neutron capture therapy, radiotherapy, fluorescence imaging, and their combinations.

关键词： supramolecular chemistry host-guest systems excipient calixarene molecular recognition

A universal polymer-assisted route to fabricate Zr-doped TiO2 nanocomposite: boosting reactive desulfurization

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Tungsten 2024年第3期6卷 596-609页

作者： yue Du Ping Li Zhi-yi Zhong Wen-Xue chen yi-Si Liu Yun-Long Xie Li-Na Zhou Kai Wang Hubei Key Laboratory of Photoelectric Materials and Devices College of Material Science and Engineering Hubei Normal University National Laboratory of Solid State Microstructures Nanjing University College of Urban and Environmental Sciences Huangshi Key Laboratory of Prevention and Control of Soil Pollution Hubei Normal University School of Chemistry Chemical Engineering and Biotechnology Nanyang Technological University

A series of transition metal ion-doped TiO2composites were prepared by polyethyleneimine-assisted solvent-free *** to the similar electronegativity and ionic radius of Ti and Zr ions,the introduction of Zr element to TiO2can effectively improve its surface acidity and introduce more defect sites on the ***-fabricated Zr-doped TiO2nanocomposite exhibits the formation of Zr-Ti bond,strong surface acidity,connected mesoporous channels,and relatively high *** remarkable properties contribute to its adsorption-oxidation-desulfurization capacity toward thiophene-type sulfides,which can remove 500 ×10-6dibenzothiophene from the model fuel within 100 min at low reaction *** polymer-induced self-assembly method can reduce organic solvent usage,pollutant emissions,and energy consumption,which provides an efficient and practical way to prepare porous metal oxide-based catalysts in future.

关键词： Oxidative desulfurization Transition metal ion-doped TiO 2 nanocomposite Dibenzothiophene Solvent-free self-assembly method