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信息时代微信在高职院校图书馆的应用

佳木斯职业学院学报 2014年第4期30卷 484-485页

作者：岳素华广东工程职业技术学院广东广州510520

微信是腾讯推出的免费手机通讯软件,微信公众平台在高职院校图书馆得到广泛的应用。本位介绍了信息时代下微信的应用特点、微信在高职院校图书馆应用的意义、微信在高职院校图书馆应用的可行性、信息时代高职院校图书馆服务面临着新的... 详细信息

微信是腾讯推出的免费手机通讯软件,微信公众平台在高职院校图书馆得到广泛的应用。本位介绍了信息时代下微信的应用特点、微信在高职院校图书馆应用的意义、微信在高职院校图书馆应用的可行性、信息时代高职院校图书馆服务面临着新的挑战、信息时代下微信应用于高职院校图书馆服务的方式。

关键词：特点意义可行性挑战方式

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浅谈高校图书馆服务功能的提升与拓展

南昌教育学院学报 2013年第10期28卷 68-,70页

作者：岳素华广东工程职业技术学院广东广州510520

目前,已经进入到了信息化时代。在知识经济的背景下,高校图书馆建设也需要不断完善。面临随之而来的各种机遇和挑战,高校图书馆将自己的着眼点和落脚点扩展到了服务创新。本文通过分析高校图书馆服务功能的现状,探索和研究图书馆服务功... 详细信息

目前,已经进入到了信息化时代。在知识经济的背景下,高校图书馆建设也需要不断完善。面临随之而来的各种机遇和挑战,高校图书馆将自己的着眼点和落脚点扩展到了服务创新。本文通过分析高校图书馆服务功能的现状,探索和研究图书馆服务功能的提升与拓展空间。

关键词：高校图书馆服务功能提升与扩展

Indium-mediated Reaction of a-Bromoesters with Arylazides in Aqueous Media: A Novel Method for Preparation of N-Aryl Glycine Esters

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Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

中国化学会第四届有机化学学术会议

作者： DING, Jin-Chang WU, hua-yue su,Wei-Ke CHEN, Xi-An CHEN, Jiu-Xi XU, Rong (Department of Chemistry, Wenzhou Normal College, Wenzhou 325027)

＜正＞Metal-mediated reactions in aqueous media have received considerable attention in the last decade. such reactions offer a number of advantages over conventional organometallic reactions in organic *** are practically convenient, environmently friendly and do not require anhydrous organic solvents. Herein we would like to report the reaction of α-bromoesters with arylazides to give N-ary1 glycine esters mediated by indium in aqueous media. One of the notable advantages of the present procedure is their mild, neutral and environmently friendly reaction conditions, easy availability of starting materials, simple operation, and good yields. The results were summarized as follows.

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu yue Li hua Zhang Lian-Lian Wang Wen-Wen Liu Xin Yang Ming-Zhao Xiao Hao-Ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(Psuch as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

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挖掘机回转减速机齿轮啮合装配

建筑机械化 2016年第5期37卷 64-66页

作者：董彪赵兴虎岳苏华徐州徐工挖掘机械有限公司江苏徐州221004

回转减速机齿轮啮合装配是制约大型挖掘机及回转型工程机械生产效率提升的重要因素,本文简单介绍几种液压挖掘机上回转减速机安装的工艺方法及装备,为回转减速机安装提供参考。

关键词：挖掘机回转减速机齿轮啮合装配方法

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li Wen‑Xia su Jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan yue‑Peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Equilibrium Folding of Porcine Insulin Precursor——A Simple Method in Study of In Vitro Folding/Unfolding of the Disulfide-Containing Proteins

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Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

华东六省一市生物化学与分子生物学学会2006年学术交流会

作者： Jie Zhao, Qi-Long huang,yue-hua Tang, su-Qing Shao,Gen-Jun Xu,and You-Min Feng (College of Life Science,Zhejiang Sc-Tech University,Hangzhou 310018, China) (Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, the Chinese Academy of Sciences, 320 yue-Yang Road, Shanghai 200031, China)

Proteins are working molecules in the cell kingdom (1). The translated linear polypeptide from mRNA must undergo a folding process, then become a protein molecule with specific structure and biological function. Therefore, protein folding is a fundamental problem in life science, which had been studying since Anfinsen and co-workers first demonstrated that the three-dimensional structure of a globular protein is uniquely determined by its amino acid sequence and a lot of significant advances have been made in the understanding of protein folding through experimental and theoretical approaches. In the investigations of the protein folding pathway, the proteins with disulfide linkages are frequently chosen as models, because the formation of disulfide bridges is always coupled with folding and assembly, which can be used as a unique probe for the study of the protein folding and assembly. the insulin superfamily members are good model proteins for the folding studies of disulfide -containing proteins.

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu Wei Wan Xiuqin Rao yue Lin Gen Wei Jun Ying Fuzhou hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen su-hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin