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Visual analysis of abdominal aortitis treatment using the CiteSpace bibliometric method

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World Journal of Clinical Cases 2024年第21期12卷 4717-4725页

作者： Si-En Guo yuan-biao meng Zan-Man Zhang Yu-Lan Zhang Qi-Sen Yao Xiao Qin Department of Vascular Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530000Guangxi Zhuang Autonomous RegionChina

BACKGROUND Abdominal aortitis can induce aneurysms,and tumor rupture can lead to organ ischemia or even sudden *** present,there is a lack of extensive understanding and identification of key problems in the treatment of abdominal aortitis,which needs to be further analyzed using bibliometric *** To discuss the research hotspot and development trend of abdominal aortitis *** We searched the English literature(published from January 1,2000 to March 12,2024)on the treatment of abdominal aortitis in the Web of Science ***,we identified and screened duplicate literature using CiteSpace 6.1R2 *** conducted an analysis of the number of papers,a co-occurrence analysis of the authors and institutions,and co-occurrence and cluster analyses of the ***,we drew the author,institution,and keywords of the studies into graphs for ***,we expounded on the author,institutional network interactions,and hot keywords of the studies on the treatment of abdominal *** We included 210 English literature articles involving 190 authors;the author cooperation team was mainly represented by Caradu Caroline,Berard Xavier,Lu Guanyi,Harada Kenichi,and Sharma Ashish *** the keyword analysis,highfrequency keywords include abdominal aortic aneurysm(38),abdominal aorta(24),Takayasu arteritis(22),*** three most central keywords were disease(0.69),classification(0.68),and abdominal aortic aneurysm(0.55).The first nine clusters of keywords are case report,abdominal aortic aneurysm,Takayasu arteritis,dyspnea hematuria,aortic elastic,IgG4-related disease,report,mid aortic dysplastic syndrome,and *** the keyword emergent analysis,14 emergent words were *** them,seven keywords with strong abruptness were Takayasu arteritis,abdominal aortic aneurysm,disease,retroperitoneal fibrosis,expression,management,and large vessel *** the past 3 years,the incidences of abdominal aortic aneurysm(intensit

关键词： Abdominal aortitis Treatment Abdominal aortic aneurysm CiteSpace Visualization Cluster

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脾脏在特发性门静脉高压症形成中的作用研究

中华肝脏病杂志 2006年第2期14卷 133-134页

作者：王莉韩炜周涛袁孟彪山东大学齐鲁医院消化内科济南250012

转发性门静脉高压症（IPH）是病因不明的疾病，本研究的目的是探讨脾大的发生机制及脾脏血流量在IPH形成中的作用。

关键词：脾高血压门静脉门静脉压

选择性COX-2抑制剂对大鼠实验性肝癌早期干预的研究

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山东大学学报（医学版） 2006年第7期44卷 694-697页

作者：谢英慧袁孟彪山东大学齐鲁医院消化内科山东济南250012

目的:观察环氧化酶2(cyclooxygenase-2,COX-2)抑制剂对大鼠肝癌的发生及肿瘤血管生成的早期干预效果及作用机制。方法:将实验大鼠分为两组:单纯诱导组(12只)和药物干预组(40只),均给予二乙基亚硝胺(diethylnitrosamine,DEN)诱发大鼠实... 详细信息

目的:观察环氧化酶2(cyclooxygenase-2,COX-2)抑制剂对大鼠肝癌的发生及肿瘤血管生成的早期干预效果及作用机制。方法:将实验大鼠分为两组:单纯诱导组(12只)和药物干预组(40只),均给予二乙基亚硝胺(diethylnitrosamine,DEN)诱发大鼠实验性肝癌,药物干预组同时给选择性COX-2抑制剂罗非昔布(Rofecoxib)进行治疗,于第6周和第9周分批处死实验大鼠,观察病理变化;采用免疫组化法检测肝脏COX-2、肿瘤微血管密度(MVD)、抗凋亡基因Bcl-2和增殖细胞核抗原(proliferating cell nuclear an-tigen,PCNA)情况。结果:病理切片显示药物干预组大鼠肝脏的病变程度较单纯诱导组减轻;COX-2、Bcl-2在第6周及第9周、PCNA在第9周的表达干预组均低于诱导组(分别为P0.05)。结论:COX-2抑制剂干扰和减缓了大鼠实验性肝癌的进程,其作用机制可能主要是通过诱导细胞凋亡及抑制细胞增殖而实现,对于肿瘤血管生成的抑制作用在诱癌早期未能显示。

关键词：肝肿瘤环氧合酶环氧合酶2抑制剂大鼠

环氧化酶2在大鼠肝脏癌变过程中的表达及意义

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山东大学学报（医学版） 2005年第7期43卷 602-604,608页

作者：谢英慧袁孟彪山东大学齐鲁医院消化内科山东济南250012

目的:了解环氧化酶2(COX-2)在大鼠肝脏癌变过程中的表达规律及与肝癌的关系。方法:用二乙基亚硝胺(DEN)诱发大鼠肝癌模型,采用逆转录聚合酶链反应(RT-PCR)和免疫组织化学方法,检测COX-2在大鼠肝脏癌变过程中的表达。结果:COX-2表达在大... 详细信息

目的:了解环氧化酶2(COX-2)在大鼠肝脏癌变过程中的表达规律及与肝癌的关系。方法:用二乙基亚硝胺(DEN)诱发大鼠肝癌模型,采用逆转录聚合酶链反应(RT-PCR)和免疫组织化学方法,检测COX-2在大鼠肝脏癌变过程中的表达。结果:COX-2表达在大鼠肝脏癌变过程中呈动态变化,在诱癌的第6周即可出现,在肝癌晚期表达最明显,而在正常肝组织未见表达。结论:COX-2表达与大鼠肝脏癌变关系密切,COX-2参与了大鼠肝癌的发病过程。

关键词：肝肿瘤环氧化酶基因表达大鼠

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血清Ⅳ型胶原在良恶性肝肿瘤鉴别中的价值

临床肝胆病杂志 1998年第1期14卷 50-52页

作者：刘春安袁孟彪山东省滕州市中心人民医院山东医科大学附属医院

对５８例肝癌、２９良性肝肿瘤、１３其他恶性肿瘤和３０名正常对照者例用一步夹心酶免疫法测定了血清Ⅳ型胶原（Ⅳ－Ｃ）水平。结果显示，肝癌组血清ＩＶ－Ｃ显著高于良性肝肿瘤、其它恶性肿瘤及正常对照组（Ｐ均＜０．００１）；血清... 详细信息

对５８例肝癌、２９良性肝肿瘤、１３其他恶性肿瘤和３０名正常对照者例用一步夹心酶免疫法测定了血清Ⅳ型胶原（Ⅳ－Ｃ）水平。结果显示，肝癌组血清ＩＶ－Ｃ显著高于良性肝肿瘤、其它恶性肿瘤及正常对照组（Ｐ均＜０．００１）；血清ＩＶ－Ｃ对良、恶性肝肿瘤鉴别诊断的准确率为９０．８０％；对原发性肝癌（ＰＨＣ）的敏感性及特异性分别为９１．４８％和８９．６５％，敏感性优于血清ＡＦＰ，血清ＩＶ－Ｃ与ＡＦＰ联合测定对ＰＨＣ的敏感性及待异性分别为９５．７４％和８６．２０％。提示血清ＩＶ－Ｃ对良、恶性肝肿瘤的鉴别诊断具有一定价值。

关键词： Ⅳ型胶原肝肿瘤血清鉴别诊断

Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO2

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Journal of Energy Chemistry 2025年第1期100卷 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu Xiaoling Liu biao meng Tao Chen Yu Han Jun Wang Shibo Xi Yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Advanced Membranes and Porous Materials Center Physical Sciences and Engineering Division King Abdullah University of Science and Technology Institute of Sustainability for Chemicals Energy and Environment A*STAR (Agency for Science Technology and Research) College of Materials Science and Engineering Sichuan University

The synergy of single atoms （SAs） and nanoparticles （NPs） has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction （CO2RR）;however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly（ionic liquids）(PIL) precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO2into *** Ni K-edge X-ray absorption near-edge structure （XANES） spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO2,the coexistence of Ni SAs and NPs strengthened the CO2activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO2→*COOH step,and therefore promoted the catalysis efficiency.

关键词： Activation energy

Direct and rapid detection of serum amino acid and monoamine neurotransmitters to assist the diagnosis of panic disorder

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Science China Chemistry 2025年第1期68卷 377-384页

作者： Shiwen Liu Xuerui Wan meng Zhao Jiaqi Wang Weilan Wu Linlin You Yonggui yuan Qian Xu Rong Gao Key Laboratory of Environmental Medicine Engineering Ministry of Education School of Public Health Southeast University Key Laboratory of Modern Toxicology of Ministry of Education Department of Hygienic Analysis and Detection School of Public HealthNanjing Medical University Department of Psychosomatics and Psychiatry Zhongda Hospital School of Medicine Southeast University

The measurement of amino acid and monoamine neurotransmitters（NTs） in serum plays a central role in the identification and monitoring of clinical panic disorder（PD）. However, the strong polarity and chemical heterogeneity of NTs make direct extraction and rapid detection extremely challenging. Herein, we developed a strategy that integrated solid phase extraction based on magnetic Fe3O4coated with polydopamine（Fe3O4@PDA） and direct analysis of mass spectrometry in real time（DART-MS） for quantification of 10 NTs. We systematically investigated the optimal conditions of this strategy to achieve good accuracy and precision. Compared with existing magnetic solid phase extraction methods for NTs detection in biological samples, this strategy could adsorb more targets while having similar adsorption efficiencies, and the total process time was reduced by an average of 69.42%. We rapidly determined the metabolic abnormality of 6 types of NTs in the serum of PD patients and demonstrated their diagnostic accuracy. In addition, an outstanding feature of PD in which tryptophan was more metabolized by the KYN pathway and the 5-hydroxytryptamine pathway was inhibited could be elucidated by this strategy. Our results highlighted the potential ability of Fe3O4@PDA coupled with DART-MS to assist in the clinical diagnosis of PD.

关键词： neurotransmitters panic disorder magnetic solid phase extraction direct analysis of mass spectrometry in real time

Mechanism of inflammatory response and therapeutic effects of stem cells in ischemic stroke:current evidence and future perspectives

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Neural Regeneration Research 2025年第1期20卷 67-81页

作者： Yubo Wang Tingli yuan Tianjie Lyu Ling Zhang meng Wang Zhiying He Yongjun Wang Zixiao Li Vascular Neurology Department of NeurologyBeijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Shanghai Engineering Research Center of Stem Cells Translational Medicine ShanghaiChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Institute for Regenerative Medicine Shanghai East HospitalSchool of Life Sciences and TechnologyTongji UniversityShanghaiChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina

Ischemic stroke is a leading cause of death and disability worldwide,with an increasing trend and tendency for onset at a younger ***,in particular,bears a high burden of stroke *** recent years,the inflammatory response after stroke has become a research hotspot:understanding the role of inflammatory response in tissue damage and repair following ischemic stroke is an important direction for its *** review summarizes several major cells involved in the inflammatory response following ischemic stroke,including microglia,neutrophils,monocytes,lymphocytes,and ***,we have also highlighted the recent progress in various treatments for ischemic stroke,particularly in the field of stem cell ***,understanding the complex interactions between inflammation and ischemic stroke can provide valuable insights for developing treatment strategies and improving patient *** cell therapy may potentially become an important component of ischemic stroke treatment.

关键词： cell therapy immune cell inflammatory ischemic stroke stem cell

Innovative dual-mode device integrating capacitive desalination and solar vapor generation for high-efficiency seawater desalination

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Journal of Energy Chemistry 2025年第1期100卷 171-179页

作者： Jiacheng Wang Zhaoyu Chen Ruduan yuan Jiaxin Luo Ben Zhang Keju Ji meng Li Juanxiu Xiao Kuan Sun National Innovation Center for Industry-Education Integration of Energy Storage Technology MOE Key Laboratory of Low-grade Energy Utilization Technologies and SystemsCollege of Energy & Power Engineering Chongqing University Xuefeng Mountain Energy Equipment Safety National Observation and Research Station CQU-NUS Renewable Energy Materials & Devices Joint Laboratory Chongqing University Southwest Technology and Engineering Research Institute Jiangsu Provincial Key Laboratory of Bionic Functional Materials College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and Astronautics State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University

Solar-driven interface evaporation with high solar-to-steam conversion efficiency has shown great potential in seawater ***,due to the influence of latent heat and condensation efficiency,the water yield from solar-driven interface evaporation remains insufficient,posing a significant challenge that requires *** this work,we designed a dual-mode high-flux seawater desalination device that combines solar-driven interface evaporation and capacitive *** utilizing coupled desalination materials exhibiting both photothermal conversion and capacitance activity,the device demonstrated photothermal evaporation rates of 1.41 and 0.97 kg m-2h-1for condensate water yield under one-sun ***,the device exhibited a salt adsorption capacity of up to48 mg g-1and a salt adsorption rate of 2.1 mg *** addition,the salt adsorption capacity increased by approximately 32% under one-sun ***,photo-enhanced capacitive desalination performance was explored through numerical simulations and theoretical *** calculations and characterizations confirmed that the defect energy levels formed by the introduction of sulfur vacancies can effectively widen the light absorption range,improve photothermal conversion performance,and stimulate more photoelectrons to participate in capacitive ***,the electron distribution state of molybdenum disulfide with sulfur vacancies and surface defect sites contributes to ion/electron transport at the solid-liquid *** work provides a novel pathway for integrating solar vapor generation with other low-energy desalination technologies.

关键词： Desalination