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Adiabatic shear banding of hot-rolling Ti–6Al–4V alloy subjected to dynamic shearing and uniaxial dynamic compression

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Rare Metals 2015年第9期34卷 632-637页

作者： yu-meng luo Jin-Xu Liu Xing-Wang Cheng Shu-Kui Li Fu-Chi Wang Wen-Wen Guo China National Key Laboratory of Science and Technology on Materials Under Shock and Impact School of Materials Science and Engineering Beijing Institute of Technology

Effect of stress state including dynamic shearing and uniaxial dynamic compression on adiabatic shear banding(ASBing) of hot-rolling Ti–6Al–4V(TC4) alloy was investigated. The absorbed energy of specimen before failure was calculated to evaluate the susceptibility to adiabatic shear band(ASB) of TC4 alloy *** show that the susceptibility to ASB of hot-rolling TC4 alloy exhibits obvious anisotropy under both dynamic shearing and uniaxial dynamic compression conditions, but the anisotropy of susceptibility to ASB under dynamic shearing condition exhibits an opposite tendency with that under uniaxial dynamic compression condition. Under the condition of uniaxial dynamic compression, material shows the highest susceptibility to ASB when loaded along transverse direction(TD) of the hot-rolling TC4, while the lowest susceptibility when loaded along rolling direction(RD). However, under the condition of dynamic shearing,the material behaves in the opposite way, demonstrating the lowest susceptibility when loaded along TD of the hotrolling TC4, while the highest susceptibility when loaded along RD.

关键词： Adiabatic shear banding Ti alloy Dynamic compressi

New lignans from the roots of Datura metel L.

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New lignans from the roots of Datura metel L.

Tilting homeostatic and dyshomeostatic microglial balance in health and disease:transforming growth factor-beta1 as a critical protagonist

中国化学会第十二届全国天然有机化学学术会议

作者： Bing-You Yang yu-meng luo Yan Liu Hai-Xue Kuang Key Laboratory of Chinese Materia Medica Heilongjiang University of Chinese MedicineMinistry of Education

Datura metel *** an annual herb that belongs to the Solanaceae family,widely distributed in *** was one of the most important anesthetics in ancient *** flower of Datura metel L.,named "yangjinhua" in Chinese and is officially listed on the Chinese *** roots of Datura metel *** been used to the treatment of cough,pain,rheumatic arthralgia,and a malignant sore,etc in Chinese folk *** achieve most effective clarify the basic substance of pharmacodynamics,the chemical constituents of the roots of Datura metel *** studied in present experiment,resembling the activity of traditional medicinal sites and expanding the medicinal parts of Datura metel L..In results,two new compounds,a new natural product and eighteen known compounds also were elucidated and the isolated compounds were evaluated for their *** new compounds were named Herpetol B(1) and Herpetol C(2),a new natural product was named 2-methoxycarbonyl-3-phenyl-1-propanol(3).The known compounds were identified as N-trans-feruloyl tyramine(4),N-trans-coumaroyltyramine(5),N-trans-p-coumar oyloctopamine(6),N-[2-(3,4-dihydroxyphenyl)-2 hydroxyethyl]-3-(4-methoxyphenyl)prop-2-enami de(7),N-cis-p-coumaroyloctopamine(8),N-cis-feruloyloctopamine(9),N-cis-coumaroyltyramine(10)[4],N-benzoyl-L-phenylalaninol(11),ω-hydroxypropioguaiacone(12),cannabisin G(13),canabisine H(14),canabisine F(15),(-)de-4’,4"-O-dimethy,lepimagnolin A(16),balanophonin B(17),leptolepisol D(18),thero-2,3-bis-(4-hydroxy-3-methoxypheyl)-3-methoxy-propanol(19),eyt hero-2,3-bis-(4-hydroxy-3-methoxypheyl)-3-methoxy-propanol(20),(+)-(7 R,7’R,7"R,7’"R,8 S,8’S,8"S,8’"S)-4",4’"-Dihydroxy-3,3’,3",3’",5,5’-hexamethoxy-7,9’;7’,9-diepoxy-4,8";4’,8’"-bisoxy-8,8’-dineolignan-7",7’",9",9’"-tetraol(21) by extensive 1 D and 2 D NMR spectroscopy,and by comparison with literature *** 8,11,12,14,16,17,19 and 21 were isolated from Datura metel *** the first time.

关键词： Datura metel Solanaceae natural product chemical composition

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Neural Regeneration Research 2025年第10期20卷 2895-2897页

作者： Nicolas Hugues yu luo Department of Molecular and Cellular Biosciences University of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program University of CincinnatiCincinnatiOHUSA Division of Immunobiology Cincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineCincinnatiOHUSA

Adult microglia,by continuously sensing changes in their environment and communicating with nearly all brain cell types,are considered to be the immune sentinels of the *** the healthy central nervous system(CNS),microglia display a unique molecular homeostatic signature(i.e.,Tmem119,P2ry12,Sall1,Siglech,Gpr34,and Hexb)(Figure 1A).

关键词： Figure signature critical

Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： yumeng Wang Qinyi Guo Bin Hu Haiwen luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

Exploring practical methods for detecting k-nonseparability in multipartite quantum states

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 255-256页

作者： Shunlong luo Academy of Mathematics and Systems Science Chinese Academy of Sciences

Quantum entanglement, referred to as “spooky action at a distance” by Einstein, is not only an intriguing and fascinating feature of quantum theory challenging our classical intuitions about locality and correlations, but also has practical and profound implications for quantum technologies. Initially described by Einstein, Podolsky and Rosen, as well as by Schro¨dinger, entanglement now has become a basic and crucial ingredient for both foundational and experimental investigations of the quantum world.

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Impact of ocean data assimilation on the seasonal forecast of the 2014/15 marine heatwave in the Northeast Pacific Ocean

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 24-31页

作者： Tiantian Tang Jiaying He Huihang Sun Jingjia luo Institute for Climate and Application Research(ICAR)/Key Laboratory of Meteorological Disaster Nanjing University of Information Science and TechnologyNanjingChina

A remarkable marine heatwave,known as the“Blob”,occurred in the Northeast Pacific Ocean from late 2013 to early 2016,which displayed strong warm anomalies extending from the surface to a depth of 300 *** study employed two assimilation schemes based on the global Climate Forecast System of Nanjing University of Information Science(NUIST-CFS 1.0)to investigate the impact of ocean data assimilation on the seasonal prediction of this extreme marine *** sea surface temperature(SST)nudging scheme assimilates SST only,while the deterministic ensemble Kalman filter(EnKF)scheme assimilates observations from the surface to the deep *** latter notably improves the forecasting skill for subsurface temperature anomalies,especially at the depth of 100-300 m(the lower layer),outperforming the SST nudging *** excels in predicting both horizontal and vertical heat transport in the lower layer,contributing to improved forecasts of the lower-layer warming during the *** improvements stem from the assimilation of subsurface observational data,which are important in predicting the upper-ocean *** results suggest that assimilating ocean data with the EnKF scheme significantly enhances the accuracy in predicting subsurface temperature anomalies during the Blob and offers better understanding of its underlying mechanisms.

关键词： Seasonal forecast Ocean data assimilation Marine heatwave Subsurface temperature

P2Y1 receptor in Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 440-453页

作者： Shan luo Yifei Wang Tatsuhiro Hisatsune Department of Integrated Biosciences The University of TokyoKashiwaJapan

Alzheimer’s disease is the most frequent form of dementia characterized by the deposition of amyloid-beta plaques and neurofibrillary tangles consisting of hyperphosphorylated *** amyloid-beta plaques has been a primary direction for developing Alzheimer’s disease treatments in the last ***,existing drugs targeting amyloid-beta plaques have not fully yielded the expected results in the clinic,necessitating the exploration of alternative therapeutic *** evidence unravels that astrocyte morphology and function alter in the brain of Alzheimer’s disease patients,with dysregulated astrocytic purinergic receptors,particularly the P2Y1 receptor,all of which constitute the pathophysiology of Alzheimer’s *** receptors are not only crucial for maintaining normal astrocyte function but are also highly implicated in neuroinflammation in Alzheimer’s *** review delves into recent insights into the association between P2Y1 receptor and Alzheimer’s disease to underscore the potential neuroprotective role of P2Y1 receptor in Alzheimer’s disease by mitigating neuroinflammation,thus offering promising avenues for developing drugs for Alzheimer’s disease and potentially contributing to the development of more effective treatments.

关键词： astrocytes neuroinflammation P2Y1 receptor purinergic receptor

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

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Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan Sun Lulin Li Jian luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation

In memoriam:Shizhu Wen(1932-2023)

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Friction 2024年第7期12卷 1341-1346页

作者： Jianbin luo Yonggang meng yu TIAN State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing 100084China

Professor Shizhu Wen,the winner of the 2015 Tribology Gold Medal,passed away due to illness on November 3,2023,at the age of *** was a professor of Tsinghua University,an academician of the Chinese Academy of Sciences,and the Honorary President of the Chinese Tribology Institute(CTI)from 1997 to *** Wen was born in 1932 in Jiangxi Province of China and graduated from Tsinghua University in 1955,where he was awarded the Outstanding Graduate Gold Medal and then remained as an assistant professor at the *** Wen was promoted to full professor in *** had undertaken tribology research at the Imperial College London in 1979 and *** 1985,he presided over the establishment of the State Key Laboratory of Tribology(SKLT)of Tsinghua University and served as the first director of the SKLT.

关键词： sided professor zhu