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Segregation of binary particles in gas-solid fluidized bed

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Frontiers of Chemical Science and Engineering 2024年第6期18卷 113-121页

作者： Yaxiong yu Feng Lu Xuan he fei Wei Chenxi Zhang Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China School of Chemical Engineering and Technology Xi’an Jiaotong UniversityXi’an 710049China Ordos Laboratory Ordos 017010China Institute for Carbon Neutrality Tsinghua UniversityBeijing 100084China

Particle segregation and mixing behavior play a crucial role in industrial *** study investigates the saturated jetsam fraction,which indicates the maximum capacity of flotsam to entrain jetsam,in an initially separated binary fluidized bed with particle size *** to the value of saturated jetsam fraction,three distinct regimes-segregation,mixing,and an intermediate regime-are ***,intriguing relationships between the saturated jetsam fraction and superficial gas velocity are observed,exhibiting monotonic trends in both the segregation and mixing regimes,while a unique volcano-shaped curve in the intermediate ***,a comprehensive entrainment model based on two-fluid model elucidates the observed phenomena,emphasizing the significance of mixing behavior in fluidized layer on the saturated jetsam *** work offers potential insights for evaluating segregation in industrial applications.

关键词： fluidized bed segregation binary bubbles entrainment

An efficient method of sorting liver stem cells by using immuno-magnetic microbeads

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World Journal of Gastroenterology 2006年第19期12卷 3050-3054页

作者： yu-fei he Yin-Kun Liu Dong-Mei Gao Jun Chen Peng-yuan Yang Institute Zhongshan Hospital Fudan University Shanghai 200032 China Center of Proteomics BioMedical Institutes Fudan University Shanghai 200032 China

AIM： To develop a method to isolate liver stem cells fast and efficiently. METHODS： Fetal mouse liver cells were characterized by cell surface antigens （c-Kit and CD45/TER119） using flow cytometry. The candidate liver stem cells were sorted by using immuno-magnetic microbeads and identified by -lone-forming culture, RT-PCR and immunofluorescence says. RESULTS： The c-Kit-（CD45/TER119）- cell population with 97.9% of purity were purified by immuno-magnetic microbeads at one time. The yield of this separation was about 6% of the total sorting cells and the cell viability was above 98%. When cultured in vitro these cells had high clone-forming and self-renewing ability and expressed markers of hepatocytes and bile duct cells. Functionally mature hepatocytes were observed after 21 d of culture. CONCLUSION： This method offers an excellent tool for the enrichment of liver stem cells with high purity and viability, which could be used for further studies. It is fast, efficient, simple and not expensive.

关键词： Liver stem cells Immuno-magnetic microbe.ads Sorting Flow cytometry

Phase Patterning of Poly(oxime-ester)for Information Encryption by Photo-induced Isomerization

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Chinese Journal of Polymer Science 2024年第10期42卷 1488-1494,I0010页

作者： yu-Fan Yang yun Bai Yi-Bao Li Chang-fei he School of Chemistry and Chemical Engineering Gannan Normal UniversityGanzhou341000China

Crystal polymers or liquid crystal elastomers undergo a phase transition that results in a change in the corresponding optical properties,which has the potential to be applied in areas such as information encryption and *** utilization of these materials for patterning purposes requires different phase transition ***,once prepared,altering the phase transition temperature of them presents significant ***,a poly(oxime-ester)(POE)network is developed to achieve high-resolution and multilevel patterning by photo-induced *** as-prepared POE exhibits the ability to transition from an opaque state to a transparent state under temperature stimuli,with the transition temperature and kinetics dependent on UV light exposure ***,complex patterns and information can be encrypted through different selective regional exposure time and decrypted under specific temperature or cooling ***,we illustrate an example of temporal communication,where cooling time or temperature serves as the encoded *** research expands the application scope of advanced encryption materials,showcasing the potential of POE in dynamic information encryption and decryption processes.

关键词： Poly(oxime-ester) Isomerization Phase patterning Information encryption

Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury

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Neural Regeneration Research 2024年第7期19卷 1608-1617页

作者： Yanan Dou Xiaowei fei Xin he yu Huan Jialiang Wei Xiuquan Wu Weihao Lyu Zhou fei Xia Li fei fei Department of Neurosurgery Xijing HospitalAir Force Military Medical UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology Xijing HospitalAir Force Military Medical UniversityXi’anShaanxi ProvinceChina

Elevated intraocular pressure(IOP)is one of the causes of retinal ischemia/reperfusion injury,which results in NRP3 inflammasome activation and leads to visual *** is repo rted to play a protective role in neuroinflammation in the ***,the effects of Homerla on NLRP3inflammasomes in retinal ischemia/reperfusion injury caused by elevated IOP remain *** our study,animal models we re constructed using C57BL/6J and Homer1^(flox/-)/Homerla^(+/-)/Nestin-Cre^(+/-)mice with elevated IOP-induced retinal ischemia/repe rfusion *** in vitro expe riments,the oxygen-glucose deprivation/repe rfusion injury model was constructed with M uller *** found that Homerla ove rexpression amelio rated the decreases in retinal thickness and Muller cell viability after ischemia/reperfusion ***,Homerla knockdown promoted NF-κB P65^(Ser536)activation via caspase-8,NF-κB P65 nuclear translocation,NLRP3 inflammasome formation,and the production and processing of interleukin-1βand inte *** opposite results we re observed with Homerla ove ***,the combined administration of Homerla protein and JSH-23 significantly inhibited the reduction in retinal thickness in Homer1^(flox/-)Homer1a^(+/-)/Nestin-Cre^(+/-)mice and apoptosis in M uller cells after ischemia/reperfusion *** together,these studies demonstrate that Homer1a exerts protective effects on retinal tissue and M uller cells via the caspase-8/NF-KB P65/NLRP3 pathway after I/R injury.

关键词： caspase-8 Homer1a interleukin-18 interleukin-1β intraocular pressure ischemia/reperfusion injury JSH-23 Müller cells NLRP3 nuclear factor-kB p65 retina

Stress corrosion cracking behavior of buried oil and gas pipeline steel under the coexistence of magnetic field and sulfate-reducing bacteria

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Petroleum Science 2024年第2期21卷 1320-1332页

作者： Jian-yu he fei Xie Dan Wang Guang-Xin Liu Ming Wu yue Qin College of Petroleum Engineering Liaoning Petrochemical UniversityFushun113001LiaoningChina Key Laboratory of Oil and Gas Storage and Transportation Technology in Liaoning Province Fushun113001LiaoningChina State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing100084China PipeChina West East Gas Pipeline Company Shanghai200120China

Magnetic field and microorganisms are important factors influencing the stress corrosion cracking(SCC)of buried oil and gas pipelines. Once SCC occurs in buried pipelines, it will cause serious hazards to the soil environment. The SCC behavior of X80 pipeline steel under the magnetic field and sulfate-reducing bacteria(SRB) environment was investigated by immersion tests, electrochemical tests, and slow strain rate tensile(SSRT) tests. The results showed that the corrosion and SCC sensitivity of X80 steel decreased with increasing the magnetic field strength in the sterile environment. The SCC sensitivity was higher in the biotic environment inoculated with SRB, but it also decreased with increasing magnetic field strength, which was due to the magnetic field reduces microbial activity and promotes the formation of dense film layer. This work provided theoretical guidance on the prevention of SCC in pipeline steel under magnetic field and SRB coexistence.

关键词： Magnetic field Sulfate-reducing bacteria Film layer Stress corrosion cracking Oil and gas pipelines

Targeting immunometabolism by active ingredients derived from traditional Chinese medicines for treatment of rheumatoid arthritis

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Chinese herbal Medicines 2021年第4期13卷 451-460页

作者： yu-fei he Chu-tian Mai Hu-dan Pan Liang Liu Hua Zhou Ying Xie State Key Laboratory of Quality Research in Chinese Medicines Macao University of Science and TechnologyTaipaMacao(SAR)China

Rheumatoid arthritis(RA),the most common inflammatory arthropathy word wild,is a systemic autoimmune disease that mainly affects the synovium of joints with a high disability *** misregulation has emerged as a fundamental pathogenesis of RA linked to immune cell dysfunction,while targeting immunometabolism provides a new and effective approach to regulate the immune responses and thus alleviate the symptom of ***,natural active compounds from traditional Chinese medicines(TCMs)have potential therapeutic effects on RA and regulating *** this review,in addition to updating the connection between cellular metabolism and cell function in immune cells of RA,we summarized that the anti-inflammatory mechanisms of the potential natural compounds from TCM by targeting metabolic reprogramming of immune cells,and discusses them as a rich resource for providing the new potential paradigm for the treatment of RA.

关键词： natural compounds immune cells immunometabolism rheumatoid arthritis traditional Chinese medicines

Bioinformatics analysis of metastasis-related proteins in hepatocellular carcinoma

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World Journal of Gastroenterology 2008年第38期14卷 5816-5822页

作者： Pei-Ming Song Yang Zhang yu-fei he Hui-Min Bao Jian-Hua Luo Yin-Kun Liu Peng-yuan Yang Xian Chen School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai 200030 China Institute of Biomedical Science Fudan University Shanghai 200320 China Department of Biochemistry and Biophysics University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 United States

AIM: To analyze the metastasis-related proteins in hepatocellular carcinoma (HCC) and discover the biomarker candidates for diagnosis and therapeutic intervention of HCC metastasis with bioinformatics tools. METHODS: Metastasis-related proteins were determined by stable isotope labeling and MS analysis and analyzed with bioinformatics resources, including Phobius, Kyoto encyclopedia of genes and genomes (KEGG), online mendelian inheritance in man (OMIM) and human protein reference database (HPRD). RESULTS: All the metastasis-related proteins were linked to 83 pathways in KEGG, including MAPK and p53 signal pathways. Protein-protein interaction network showed that all the metastasis-related proteins were categorized into 19 function groups, including cell cycle, apoptosis and signal transduction. OMIM analysis linked these proteins to 186 OMIM entries. CONCLUSION: Metastasis-related proteins provide HCC cells with biological advantages in cell proliferation,migration and angiogenesis, and facilitate metastasis of HCC cells. The bird's eye view can reveal a global characteristic of metastasis-related proteins and many differentially expressed proteins can be identified as candidates for diagnosis and treatment of HCC.

关键词： hepatocellular carcinoma Metastasis Bioinformatics Protein-protein interaction Kyoto encyclopedia of genes and genomes

Water-soluble brown carbon in atmospheric aerosols from the resource-dependent cities:Optical properties,chemical compositions and sources

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Journal of Environmental Sciences 2024年第4期138卷 74-87页

作者： Haoji Wang yue Su Yangzheng Liu fei Xie Xingjun Zhou Ruihong yu Changwei Lü Jiang he School of Ecology and Environment Inner Mongolia UniversityHohhot 010021China Institute of Environmental Geology Inner Mongolia UniversityHohhot 010021China Environmental Monitoring Center of Inner Mongolia Hohhot 010011China

As a vital type of light-absorbing aerosol,brown carbon(BrC)presents inherent associations with atmospheric photochemistry and climate ***,the understanding of the chemical and optical properties of BrC is limited,especially in some resource-dependent cities with long heating periods in northwest *** study showed that the annual average abundances of Water-soluble BrC(WS-BrC)were 9.33±7.42 and 8.69±6.29μg/m^(3)in Baotou and Wuhai and the concentrations,absorption coefficient(Abs_(365)),and mass absorption efficiency(MAE365)of WS-BrC presented significant seasonal patterns,with high values in the heating season and low values in the non-heating season;while showing opposite seasonal trends for the Absorption Angstr?m exponent(AAE_(300-400)).Comparatively,the levels of WS-BrC in developing regions(such as cities in Asia)were higher than those in developed regions(such as cities in Europe and Australia),indicating the significant differences in energy consumption in these *** combining fluorescence excitation-emission matrix(EEM)spectra with the parallel factor(PARAFAC)model,humic-like(C1 and C2)and proteinlike(C3)substances were identified,and accounted for 61.40%±4.66%and 38.6%±3.78%at Baotou,and 60.33%±6.29%and 39.67%±4.17%at Wuhai,*** results of source apportionment suggested that the potential source regions of WS-BrC varied in heating ***-heating seasons and that the properties of WS-BrC significantly depended on primary emissions(e.g.,combustion emissions)and secondary formation.

关键词： Water-soluble brown carbon Atmospheric aerosols Optical properties PARAFAC Source apportionment

Breakthrough in Li-mediated continuous electrosynthesis of ammonia

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Science China Chemistry 2024年第10期67卷 3191-3192页

作者： fei Zhan Chang yu State Key Laboratory of Chemical Resource Engineering College of Chemical EngineeringBeijing University of Chemical TechnologyBeijing 100029China State Key Laboratory of Fine Chemicals Liaoning Key Lab for Energy Materials and Chemical EngineeringSchool of Chemical EngineeringDalian University of TechnologyDalian 116024China

Ammonia(NH3)ranks among the manufactured chemicals,with an annual production surpassing 182 million tons[1],which is an indispensable raw material for fertilizer industry and has been recognized as a promising carbon-... 详细信息

关键词： ammonia Ammonia suppl