检索结果-南通市图书馆

Chinese Physics B 2021年第4期30卷 586-590页

作者： Siyuan xu xiaoxian Zhu Ji Wang yuanfeng li Yitan Gao Kun Zhao Jiangfeng Zhu Dacheng Zhang yunlin chen Zhiyi wei school of Physics and Optoelectronic Engineering Xidian UniversityXi'an 710071 China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China university of Chinese Academy of Sciences Beijing 100049China Institute of Applied Micro-Nano Materials School of ScienceBeijing Jiaotong UniversityBeijing 100044China Songshan Lake Material Laboratory Dongguan 523808China

A convolutional neural network is employed to retrieve the time-domain envelop and phase of few-cycle femtosecond pulses from transient-grating frequency-resolved optical gating(TG-FROG) *** use theoretically generated TGFROG traces to complete supervised trainings of the convolutional neural networks,then use similarly generated traces not included in the training dataset to test how well the networks are *** retrieval of such traces by the neural network is *** our case,we find that networks with exponential linear unit(ELU) activation function perform better than those with leaky rectified linear unit(LRELU) and scaled exponential linear unit(SELU).Finally,the issues that need to be addressed for the retrieval of experimental data by this method are discussed.

关键词： transient-grating frequency-resolved optical gating convolutional neural network activation function phase retrieval algorithm

New innovations in pavement materials and engineering:A review on pavement engineering research 2021

在线全文

学校读者我要写书评

暂无评论

Journal of Traffic and Transportation Engineering(English Edition) 2021年第6期8卷 815-999页

作者： JTTE Editorial Office Jiaqi chen Hancheng Dan Yongjie Ding yangming Gao Meng Guo Shuaicheng Guo Bingye Han Bin Hong yue Hou Chichun Hu Jing Hu Ju Huyan Jiwang Jiang wei Jiang cheng li Pengfei liu yu liu Zhuangzhuang liu Guoyang Lu Jian Ouyang xin Qu Dongya Ren Chao Wang Chaohui Wang Dawei Wang Di Wang Hainian Wang Haopeng Wang yue xiao Chao xing Huining xu yu Yan xu yang lingyun You Zhanping You Bin yu Huayang yu Huanan yu Henglong Zhang Jizhe Zhang Changhong Zhou Changjun Zhou xingyi Zhu Editorial Office of Journal of Traffic and Transportation Engineering(English Edition) Chang’an UnivieristyXi’an 710064China school of Civil Engineering Central South UniversityChangsha 410075China school of Civil Engineering Chongqing Jiaotong UniversityChongqing 400074China Department of Structural Engineering Faculty of Civil Engineering and GeosciencesDelft University of TechnologyDelft 2628 CNthe Netherlands The Key Laboratory of Urban Security and Disaster Engineering of Ministry of Education Beijing University of TechnologyBeijing 100124China College of Civil Engineering Hunan UniversityChangsha 410082China school of Civil and Transportation Engineering Beijing University of Civil Engineering and ArchitectureBeijing 100044China school of Transportation Science and Engineering Harbin Institute of TechnologyHarbin 150090China College of Metropolitan Transportation Beijing University of TechnologyBeijing 100124China school of Civil Engineering&Transportation South China University of TechnologyGuangzhou 510641China school of Transportation Southeast UniversityNanjing 211189China Department of Civil&Environmental Engineering University of WaterlooWaterlooON N2L 3G1Canada Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina school of Highway Chang’an UniversityXi’an 710064China Institute of Highway Engineering RWTH Aachen UniversityAachen 52074Germany school of Transportation&Logistics Dalian University of TechnologyDalian 116024China school of Civil Engineering Southwest Jiaotong UniversityChengdu 611756China Faculty of Architecture Civil and Transportation EngineeringBeijing University of TechnologyBeijing 100124China Department of Civil Engineering Aalto UniversityEspoo 02150Finland Nottingham Transportation Engineering center(NTEC) University of NottinghamNottingham NG72RDUK State Key Laboratory of Silicate Materials for Architectures Wuhan University of TechnologyWuhan 430070China College of Transportation Engineer

Sustainable and resilient pavement infrastructure is critical for current economic and environmental *** the past 10 years,the pavement infrastructure strongly supports the rapid development of the global social *** theories,new methods,new technologies and new materials related to pavement engineering are *** of pavement infrastructure is a typical multi-physics *** of actual coupled behaviors of traffic and environmental conditions,predictions of pavement service life become more and more complicated and require a deep knowledge of pavement material *** order to summarize the current and determine the future research of pavement engineering,Journal of Traffic and Transportation Engineering(English Edition)has launched a review paper on the topic of"New innovations in pavement materials and engineering:A review on pavement engineering research 2021".Based on the joint-effort of 43 scholars from 24 well-known universities in highway engineering,this review paper systematically analyzes the research status and future development direction of 5 major fields of pavement engineering in the *** content includes asphalt binder performance and modeling,mixture performance and modeling of pavement materials,multi-scale mechanics,green and sustainable pavement,and intelligent ***,this review paper is able to provide references and insights for researchers and engineers in the field of pavement engineering.

关键词： Asphalt binder Asphalt mixture Modeling of pavement materials Multi-scale mechanics Green and sustainable pavement Intelligent pavement

Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma:A single-arm, multicenter, prospective study

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 106-112页

作者： Ren-Yi Su Sun-Bin ling Qiao-Nan Shan xu-Yong wei Rui Wang Chang-Ku Jia li Zhuang Tian Shen li-Min Ding Zhi-Dan xu Lai-Bang Luo li-Bo Sun Guang-Ming li Tai-Shi Fang Nan Jiang Kun Zhang Zhao-Jie Su Zhi-Hai Peng Ren Lang Tao Jiang Qiang He lin-Sen Ye yang yang yu-Ting He Wen-Zhi Guo liu-Gen Lan xu-Yong Sun Dong chen Zhi-Shui chen Da-wei Zhou Shao-Jun Ye Qi-Fa Ye Min Tian Jian-Hua Shi Bo Wang Jiang liu Qian Lu wei Rao Jin-Zhen Cai Tao Lv Jia-Yin yang Pu-Sen Wang lin Zhong Jing-Sheng Ma Qi-Gen li Sheng-Dong Wu Chang-Jiang Lu Cai-De Lu Dong-Hua Zhang xuan Wang Zi-Qiang li Mu-Jian Teng Jun-Jie li Wen-Tao Jiang Jian-Hua li Quan-Bao Zhang Ning-Qi Zhu Zheng-xin Wang Kang He Qiang xia Shao-Hua Song Zhi-Ren Fu wei Qiu Guo-yue Lv Rui-Peng Song Ji-Zhou Wang Zheng Wang Jian Zhou Gang chen Ying-Peng Zhao li li Ze-Min Hu Qi-Jie Luo Zhong-Zhou Si Bin xie xiao-Shun He Zhi-Yong Guo Shu-Sen Zheng xiao xu Department of Hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Transplantation Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang 330006China liver Transplantation center Beijing You’an HospitalCapital Medical UniversityBeijing 100069China Department of Hepatic Surgery National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhen 518112China Department of General Surgery Xiang’an Hospital of Xiamen UniversityXiamen 361000China Deartment of Hepatobiliary and Pancreaticosplenic Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of Hepatic Surgery and liver Transplantation center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of liver Transplantation The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530000China Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Institute of Hepatobiliary Diseases of Wuhan university Transplant Center of Wuhan UniversityHubei Key Laboratory of Medical Technology on TransplantationZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery The First Affiliated Hos

Mammalian target of rapamycin(m TOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant(LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity. Therefore, we designed a clinical trial to test whether sirolimus can improve recurrence-free survival(RFS) in hepatocellular carcinoma(HCC) patients beyond the Milan criteria after LT. This is an open-labeled, single-arm, prospective, multicenter, and real-world study aiming to evaluate the clinical outcomes of early switch to sirolimus-based regimens in HCC patients after LT. Patients with a histologically proven HCC and beyond the Milan criteria will be enrolled. The initial immunosuppressant regimens are center-specifc for the frst 4-6 weeks. The following regimens integrated sirolimus into the regimens as a combination therapy with reduced calcineurin inhibitors based on the condition of patients and centers. The study is planned for 4 years in total with a 2-year enrollment period and a 2-year follow-up. We predict that sirolimus conversion regimen will provide survival benefts for patients particular in the key indicator RFS as well as better quality of life. If the trial is conducted successfully, we will have a continued monitoring over a longer follow-up time to estimate indicator of overall survival. We hope that the outcome will provide better evidence for clinical decision-making and revising treatment guidelines based on Chinese population data.

关键词： Sirolimus Immunosuppressive agents Hepatocellular carcinoma liver transplantation Conversion

Primary animal experiment to test the feasibility of a novel Y-Z magnetic hepatic portal blocking band

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2023年第7期15卷 1286-1293页

作者： Miao-Miao Zhang chen-Guang li Shu-Qin xu Jian-Qi Mao yu-xiang Ren yu-Han Zhang Jia Ma Ai-Hua Shi Yi Lyu xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local Joint Engineering Research center for Precision Surgery&Regenerative medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Critical Care medicine China-Japan Union Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina Zonglian College Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Qide College Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Surgical Oncology Shaanxi Provincial People's HospitalXi'an 710068Shaanxi ProvinceChina

BACKGROUND Hepatic portal blood flow occlusion is a common technique for reducing hepatic hemorrhage during *** designed a novel Y-Z magnetic hepatic portal blocking band(Y-Z MHPBB)based on the principle of magnetic compression *** To introduce the Y-Z MHPBB device and verify the feasibility of this device for hepatic portal blood flow occlusion in *** Ten beagles were randomly divided into the experimental group and control *** operation time,intraoperative blood loss,the number of portal blood flow occlusions,the total time spent on adjusting the blocking band,and the average time spent on adjusting the blocking band were *** surgeons evaluated the feasibility and flexibility of the two portal occlusion *** Laparoscopic hepatectomy was successfully performed in both the experimental group and control *** was no statistical difference between the two groups in the operation time,intraoperative blood loss,and the number of hepatic portal blood flow *** respect to the total time spent on adjusting the blocking band and the average time spent on adjusting the blocking band,the experimental group showed significantly better outcomes than the control group,with a statistical difference(Pxibility;and it can be used for hepatic portal blood flow occlusion during laparoscopic hepatectomy.

关键词： Hepatic portal blood flow occlusion Laparoscopic hepatectomy Novel Y-Z magnetic hepatic portal blocking band Magnetic surgery Magnetic compression technique Beagles

Efficacy and Safety of All-oral,12-week Ravidasvir Plus Ritonavir-boosted Danoprevir and Ribavirin in Treatment-naive Noncirrhotic HCV Genotype 1 Patients:Results from a Phase 2/3 Clinical Trial in china

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2019年第3期7卷 213-220页

作者： xiaoyuan xu Bo Feng yujuan Guan Sujun Zheng Jifang Sheng xingxiang yang yuanji Ma Yan Huang Yi Kang xiaofeng Wen Jun li Youwen Tan Qing He Qing xie Maorong Wang Ping An Guozhong Gong Huimin liu Qin Ning Rui Hua Bo Ning Wen xie Jiming Zhang Wenxiang Huang Yongfeng yang Minghua lin Yingren Zhao Yanhong yu Jidong Jia Dongliang yang liang chen Yinong Ye yuemin Nan Zuojiong Gong Quan Zhang Peng Hu Fusheng Wang Yongguo li Dongliang li Zhansheng Jia Jinlin Hou chengwei chen Jinzi JWu Lai wei Peking university first hospital BeijingChina Peking university People's hospital BeijingChina Guangzhou Eighth People's hospital GuangzhouChina Beijing YouAn hospital Capital Medical UniversityBeijingChina the first affiliated hospital of Medical school of Zhejiang university HangzhouChina Sichuan Provincial People's hospital ChengduChina West china hospital Sichuan UniversityChengduChina xiangya hospital Central South UniversityChangshaChina Henan Provincial People's hospital ZhengzhouChina liuzhou People's hospital LiuzhouChina Jiangsu Province hospital NanjingChina Zhenjiang No.3 People's hospital ZhenjiangChina The Third People's hospital of Shenzhen ShenzhenChina Ruijin hospital Shanghai Jiaotong University School of MedicineShanghaiChina People's liberation Army Bayi hospital NanjingChina Shenyang Sixth People's hospital ShenyangChina The 2nd xiangya hospital of Central South university ChangshaChina xixi hospital of Hangzhou HangzhouChina Tongji Medical College of Huazhong university of Science&Technology WuhanChina The first hospital of Jilin university ChangchunChina Baoji center hospital BaojiChina Beijing Ditan hospital BeijingChina Huashan hospital affiliated to Fudan university ShanghaiChina Chongqing Medical university No.1 affiliated hospital ChongqingChina The Second hospital of Nanjing NanjingChina Fujian Fuzhou Municipal Infectious Disease hospital FuzhouChina No.1 affiliated hospital of xi'an jiaotong university Xi'anChina the first affiliated hospital of Guangxi Medical university NanningChina Beijing Friendship hospital Capital Medical UniversityBeijingChina Wuhan Union hospital WuhanChina Shanghai Public Health Clinical center ShanghaiChina Foshan No.1 People's hospital FoshanChina The Third hospital of Hebei Medical university ShijiazhuangChina Wuhan university Renmin hospital WuhanChina The affiliated hospital of Guizhou Medical university GuiyangChina The Second affiliated hospital of Chongqing Medical university ChongqingChina PLA 302 hospital Be

Background and Aims:Ravidasvir(RDV)is a new generation pangenotypic hepatitis C virus(HCV)NS5A inhibitor,with high barrier to baseline resistance-associated *** is the first phase 2/3 study conducted in china's Mainland confirming the efficacy and safety of RDV+ritonavir-boosted danoprevir+ribavirin for 12 weeks in treatment-naive noncirrhotic patients with genotype 1 infection in a large ***:In this multicenter,randomized,doubleblinded,placebo-controlled phase 2/3 trial(NCT03362814),we enrolled 424 treatment-nafve,noncirrhotic adult HCV genotype 1 *** patients were randomized at 3∶1 ratio to receive a combination of RDV 200mg once daily plus ritonavir-boosted danoprevir 100mg/100mg twice daily and oral ribavirin 1000/1200mg/day(body weightline NS5A resistance-associated species in the treatment group(76/76,per protocol set)achieved sustained virological response at 12 weeks after *** treatment-related serious adverse events were *** abnormalities showed mild or moderate severity(grade 1 and grade 2)in liver function ***:In treatment-na(i)ve,noncirrhotic HCV Chinese patients infected with HCV genotype 1,all-oral regimen of RDV+ritonavir-boosted danoprevir+ribavirin for 12 weeks was highly efficacious,safe,and well tolerated.

关键词： Ravidasvir Danoprevir HCV SVR Treatment-naive Noncirrhotic GT1

中西医结合防治术后胃肠功能紊乱临床实践指南(2023版)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国循证医学杂志 2024年第6期24卷 637-651页

作者：薛建军徐紫清侯怀晶王强魏莉莉张杰赵晓红陈丽萍丁凡帆马丽赵永强王迎斌马大青王天俊刘仁玉 Tong J Gan Nicky Robinson yurasek Frank 苏帆迟永良杨佃会刘淑娟崔苏扬魏友松陈志强秦有曹立幸陈贵平舒宽勇肖仲清张晖余剑波胡志前程化坤马武华刘国凯王秀丽曹兴华高巨孔高茵陶清王保华王均炉李洪吕翠霞张志明李天佐杨克虎兰州大学基础医学院循证医学中心兰州730000 甘肃省中医院兰州730050 甘肃省中西医结合麻醉临床医学研究中心兰州730050 西安交通大学第一附属医院西安710061 甘肃中医药大学经贸与管理学院兰州730000 兰州大学第二医院兰州730030 英国帝国理工学院英国伦敦SW72AZ 浙江大学医学院附属儿童医院杭州310005 英国伦敦中医针灸学院英国伦敦IG26QS 美国宾夕法尼亚大学美国宾夕法尼亚州19104 美国石溪大学美国纽约NY11794 英国伦敦南岸大学英国伦敦SE13NQ 美国芝加哥库克郡医院美国芝加哥60675 山东中医药大学附属医院济南250014 江苏省中医院南京210029 广东省中医院广州510030 浙江省中医院杭州310006 江西省妇幼保健院南昌330006 天津市南开医院天津300100 第二军医大学附属长征医院上海200003 黑龙江省医院哈尔滨150036 广州中医药大学第一附属医院广州510405 北京中医药大学东直门医院北京100700 河北医科大学第三医院石家庄050051 新疆医科大学附属中医医院乌鲁木齐830000 江苏省苏北人民医院江苏扬州225001 湖南省人民医院长沙410005 安徽中医药大学第一附属医院合肥230031 长春中医药大学附属医院长春130021 温州医科大学附属第一医院浙江温州325000 陆军军医大学第二附属医院重庆400037 山东中医药大学基础学院济南250013 首都医科大学附属北京世纪坛医院北京100038 世界卫生组织指南实施与知识转化合作中心兰州730000 甘肃省医学指南行业技术中心兰州730000 中国GRADE中心兰州大学兰州730000

术后胃肠功能紊乱是麻醉手术后的常见并发症。中西医结合技术在防治此类疾病上疗效确切,但目前缺少标准化和规范化的相关临床实践指南。为此,中国中西医结合学会围手术期专业委员会和中国中西结合学会麻醉专业委员会,联合甘肃省中西医... 详细信息

术后胃肠功能紊乱是麻醉手术后的常见并发症。中西医结合技术在防治此类疾病上疗效确切,但目前缺少标准化和规范化的相关临床实践指南。为此,中国中西医结合学会围手术期专业委员会和中国中西结合学会麻醉专业委员会,联合甘肃省中西医结合麻醉临床医学研究中心/甘肃省中医院麻醉疼痛医学中心及WHO指南实施与知识转化合作中心/GRADE中国中心/甘肃省医学指南行业技术中心/兰州大学循证医学中心,遵循循证指南制订的原则、方法和步骤,组建多学科专家团队,通过文献调研和专家共识确定临床问题(7个背景问题和12个临床问题)。基于系统评价/Meta分析结果,综合证据质量,权衡干预措施的利弊,考虑患者偏好和价值观,通过德尔菲法专家共识会议形成20条推荐意见。涉及对疾病的定义、病因病机、辨证分型和诊断,以及围手术期防治措施。

关键词：中西医结合术后胃肠功能紊乱指南

Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)

在线全文

学校读者我要写书评

暂无评论

Science china(Physics,Mechanics & Astronomy) 2016年第4期59卷 1-7页

作者： weiPing liu ZhiHong li JiangJun He xiaoDong Tang Gang lian Zhu An JianJun Chang Han chen QingHao chen xiongJun chen ZhiJun chen BaoQun Cui xianChao Du ChangBo Fu lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou Hanxiong Huang Ning Huang BaoLu Jia liyang Jiang Shigeru Kubono JianMin li KuoAng li Tao li yunJu li Maria Lugaro xiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren yangPing Shen Jun Su liangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu Shiwei xu ShengQuan Yan liTao yang Yao yang xiangQing yu Qian yue Sheng Zeng Huanyu Zhang Hui Zhang liYong Zhang NingTao Zhang Qiwei Zhang Tao Zhang xiaoPeng Zhang xueZhen Zhang ZiMing Zhang wei Zhao Zuo Zhao Chao Zhou Department of Nuclear Physics China Institute of Atomic Energy Beijing 102413 China Institute of Modern Physics Lanzhou 730000 China College of Nuclear Science and Engineering Sichuan University Chengdu 610065 China Department of Engineering Physics Tsinghua University Beijing 100084 China Department of Physics and Astronomy Shanghai Jiaotong University Shanghai 200240 China school of Physics and Astronomy Monash University Melbourne Victoria 3800 Australia center for Nuclear Study University of Tokyo Wako Saitama 351-0198 Japan Konkoly Observatory of the Hungarian Academy of Sciences 1121 Budapest Konkoly-Thege Miklos u. 13-17 Hungary Department of Physics University of South Dakota Vermillion SD 57069 United States school of Physics and Astronomy University of Minnesota Minneapolis MN 55455 United States Department of Physics University of Notre Dame Notre Dame IN 46556 Unites States Research center for Nuclear Physics Osaka University Suita Osaka 565-0871 Japan school of Space Science and Physics Shandong University Weihai Campus Weihai 264209 China

Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given.

关键词： direct measurement underground laboratory (25)Mg(p γ)(26)Al (19)F(p α)(16)O (13)C(α n)(16)O and (12)C(α γ)(16)O reactions Gamow window JUNA

Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2023年第3期10卷 281-298页

作者： Fei Pei Ren‑Qi Yao Chao Ren Soheyl Bahrami Timothy RBilliar Irshad HChaudry De‑Chang chen xu‑lin chen Na Cui xiang‑Ming Fang Yan Kang wei‑Qin li Wen‑xiong li Hua‑Ping liang Hong‑yuan lin Ke‑xuan liu Ben Lu Zhong‑Qiu Lu Marc Maegele Tian‑Qing Peng You Shang Lei Su Bing‑wei Sun Chang‑Song Wang Jian Wang Jiang‑Huai Wang Ping Wang Jian‑Feng xie li‑xin xie li‑Na Zhang Basilia Zingarelli xiang‑Dong Guan Jian‑Feng Wu Yong‑Ming Yao Department of Critical Care medicine the First Affiliated Hospital of Sun Yat-Sen University58 Zhongshan Er RoadYuexiu DistrictGuangzhou 510080GuangdongChina Translational medicine Research center Medical Innovation Research Division and Fourth Medical Center of the Chinese PLA General Hospital28 Fuxing RoadHaidian DistrictBeijing 100853China Department of Burn Surgery the First Affiliated Hospital of Naval Medical UniversityShanghai 200433China Ludwig-Boltzmann Institute for experimental and Clinical Traumatology 1200 ViennaAustria Department of Surgery University of Pittsburgh Medical CenterPittsburghPA 15213USA center for Surgical Research and Department of Surgery University of Alabama at BirminghamBirminghamAL 35294USA Department of Critical Care medicine Ruijin HospitalShanghai Jiaotong UniversityShanghai 200025China Department of Burns the First Affiliated Hospital of Anhui Medical UniversityHefei 230022China Department of Critical Care medicine Peking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Anesthesiology the First Affiliated HospitalZhejiang University School of MedicineHangzhou 31003China Department of Critical Care medicine West China Hospital of Sichuan UniversityChengdu 610041China Department of Critical Care medicine General Hospital of Eastern Theater Command of Chinese PLANanjing 210002China Department of Surgical Intensive Critical Unit Beijing Chao‑Yang HospitalCapital Medical UniversityBeijing 100020China State Key Laboratory of Trauma Burns and Combined InjuryResearch Institute of SurgeryDaping HospitalArmy Medical UniversityChongqing 400042China Department of Critical Care medicine Fourth Medical Center of the Chinese PLA General HospitalBeijing 100048China Department of Anesthesiology Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Critical Care medicine and Hematology the Third Xiangya HospitalCentral South UniversityChangs

Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of *** provide clinical practice recommendations on the immune function in sepsis,an expert consensus focusing on the monitoring and treatment of sepsis-induced immunosuppression was *** related to the immune monitoring and treatment of sepsis were retrieved from PubMed,Web of Science,and Chinese National Knowledge Infrastructure to design items and expert opinions were collected through an online ***,the Delphi method was used to form consensus opinions,and RAND appropriateness method was developed to provide consistency evaluation and recommendation levels for consensus *** consensus achieved satisfactory results through two rounds of questionnaire survey,with 2 statements rated as perfect consistency,13 as very good consistency,and 9 as good *** summarizing the results,a total of 14 strong recommended opinions,8 weak recommended opinions and 2 non-recommended opinions were ***,a face-to-face discussion of the consensus opinions was performed through an online meeting,and all judges unanimously agreed on the content of this *** summary,this expert consensus provides a preliminary guidance for the monitoring and treatment of immunosuppression in patients with sepsis.

关键词： Sepsis Immune function monitoring Immunomodulatory therapy Immunosuppression

Kunming mouse strain is less susceptible to elastase-induced abdominal aortic aneurysms

在线全文

学校读者我要写书评

暂无评论

Animal Models and experimental medicine 2022年第1期5卷 72-80页

作者： Haole liu Kangli Tian congcong xia Panpan wei Boyu xu weilai Fu Yankui li Yafeng li liang Bai Rong Wang weirong Wang Baohui xu Enqi liu Sihai Zhao Institute of Cardiovascular Science School of Basic Medical SciencesXi'an Jiaotong University Health Science CenterXi'anChina Laboratory Animal center Xi'an Jiaotong UniversityXi'anChina Department of Vascular Surgery The Second Hospital of Tianjin Medical UniversityTianjinChina Pain Rehabilitation Department of TCM Orthopedic center Xi'an Honghui HospitalXi'anChina Department of Vascular Surgery Stanford University School of MedicineStanfordCaliforniaUSA

Background:Porcine pancreatic elastase(PPE)is successfully used to induce abdominal aortic aneurysm(AAA)in ***,differences between mouse strains in susceptibility to PPE induction have been *** mouse is one of the most frequently used strains in china but whether it is suitable for induction of AAA by PPE application remains ***:PPE infusion(1.5 units/ml)in temporary controlled aorta was performed to induce AAAs in both C57BL/6J and Kunming *** saline(PBS)application was used as vehicle *** aorta diameters of all mice were measured at days 0 and 14 after surgery to evaluate the AAA ***:After 14 days of PPE or PBS infusion,all mice were sacrificed and aorta tissues were collected for histological staining *** the 14th day after infusion,PPE successfully induced aortic dilation in Kunming mice and typical AAA in C57BL/6J *** aorta diameter increased by 0.23 mm in Kunming mice after PPE infusion,while it was 0.72 mm in the C57BL/6J *** induced mild elastin degradation,smooth muscle cell(SMC)depletion and mural leucocyte infiltration in Kunming mice,but in PPE-sensitive C57BL/6J mice,it induced total loss of SMCs,elastin disappearance and diffused infiltrated leucocytes in aortic aneurysmal *** effects of PPE in inducing angiogenesis and upregulating matrix metalloproteinase 2 and 9 expression in Kunming mice were also weaker than that in C57BL/6J ***:At the reported dose of PPE,Kunming mouse is not as susceptible to AAA formation as C57BL/6J *** failure of PPE to induce AAA formation in Kunming mice may be associated to its inability to boost a strong inflammatory response.

关键词： abdominal aortic aneurysms C57BL/6J histology Kunming strain

Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia(2021 Edition)

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2022年第5期9卷 515-533页

作者： xian-Tao Zeng Ying-Hui Jin Tong-Zu liu Fang-Ming chen De-Gang Ding Meng Fu xin-Quan Gu Bang-Min Han xing Huang Zhi Hou Wan-li Hu xin-li Kang Gong-Hui li Jian-xing li Pei-Jun li Chao-Zhao liang xiu-Heng liu Zhi-yu liu Chun-xiao liu Jiu-Min liu Guang-Heng Luo Yi Luo wei-Jun Qin Jian-Hong Qiu Jian-xin Qiu xue-Jun Shang Ben-Kang Shi Fa Sun Guo-xiang Tian Ye Tian Feng Wang Feng Wang Yin-Huai Wang yu-Jie Wang Zhi-Ping Wang Zhong Wang Qiang wei Min-Hui xiao Wan-Hai xu Fa-xian Yi Chao-yang Zhu Qian-yuan Zhuang li-Qun Zhou xiao-Feng Zou Nian-Zeng xing Da-lin He xing-Huan Wang 无 Department of Urology Institute of UrologyZhongnan Hospital of Wuhan UniversityWuhan430071China center for Evidence-Based and Translational medicine Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Urology Tianjin Third Central Hospital Affiliated To Nankai UniversityTianjin300170China Department of Urology Henan Provincial People’s HospitalZhengzhou University People’s HospitalZhengzhou450003China Department of Urology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing102218China Department of Urology China-Japan Union Hospital of Jilin UniversityChangchun130033China Department of Urology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China Department of Urology Qinghai University Affiliated HospitalXi’ning810012China Department of Urology People’s Hospital of Hainan ProvinceHainan Affiliated Hospital of Hainan Medical University HaikouHaikou570311China Department of Urology Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou310016China Department of Urology General Hospital of Ningxia Medical UniversityYinchuan750003China Department of Urology The First Affiliated Hospital of Anhui Medical UniversityHefei230022China Department of Urology Renmin Hospital of Wuhan UniversityWuhan430060China Department of Urology The Second Hospital of Dalian Medical UniversityDalian116023LiaoningChina Department of Urology Zhujiang Hospital of Southern Medical UniversityGuangzhou510282China Department of Urology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou510080China Department of Urology Surgery Guizhou Province People’s HospitalGuiyang550002China Department of Urology Xijing Hospital of Air Force Military Medical UniversityXi’an710032China Department of Urology The 980St Hospital of the PLA Joint Logistics Support Force(Bethune International Peace Hospital of PLA)Shijiazhuang050082China Department of Urology

Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety. In 2018, we issued the guideline “2018 Standard Edition”. However much new direct evidence has now emerged and this may change some of previous recommendations. The time is ripe to develop new evidence-based guidelines, so we formed a working group of clinical experts and methodologists. The steering group members posed 31 questions relevant to the management of TUPKP for BPH covering the following areas: questions relevant to the perioperative period (preoperative, intraoperative, and postoperative) of TUPKP in the treatment of BPH, postoperative complications and the level of surgeons’ surgical skill. We searched the literature for direct evidence on the management of TUPKP for BPH, and assessed its certainty generated recommendations using the grade criteria by the European Association of Urology. Recommendations were either strong or weak, or in the form of an ungraded consensus-based statement. Finally, we issued 36 statements. Among them, 23 carried strong recommendations, and 13 carried weak recommendations for the stated procedure. They covered questions relevant to the aforementioned three areas. The preoperative period for TUPKP in the treatment of BPH included indications and contraindications for TUPKP, precautions for preoperative preparation in patients with renal impairment and urinary tract infection due to urinary retention, and preoperative prophylactic use of antibiotics. Questions relevant to the intraoperative period incorporated surgical operation techniques and prevention and management of bladder explosion. The application to different

关键词： Transurethral plasmakinetic resection of prostate Benign prostatic hyperplasia Recommendation Treatment Guideline