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Science China Earth Sciences 2010年第6期53卷 892-900页

作者： LEE Joohan kim Ki young HONG Jong Kuk JIN young Keun Korea Polar Research Institute Songdo Techno Park7-50 Songdo-dong Yeonsu-gu Incheon 406-840 Korea Department of Geophysics Kangwon National UniversityChunchon 200-701 Korea

The distribution of small fractures and water content of the Fourcade glacier on King George Island, Antarctica, was investigated in November 2006 and December 2007 by two ground-based (470-and 490-m-long profiles) and one helicopter-borne (470-m-long profile) ground-penetrating radar (GPR) surveys using 50-, 100-, and 500-MHz antennas. Radar images in the pre-migrated GPR sections are characterized by a smooth ice surface and irregular bed topography, numerous diffraction hyperbolas in the ice and at the glacier bed, strong scattering noise, and near-surface folded layers. Scattering noise above a mound in the center of the profiles is associated with an area of dense fractures extending down from the ice surface that has relatively low reflection strength. Near the northeast ends of the profiles where few englacial fractures occur, scattering noise may result from the presence of warmer ice. A water-filled conduit and an air-filled cavity are interpreted as the source of two distinct hyperbolas in sub-glacial valleys based on the polarity of the reflections. Through migration velocity analysis on 106 hyperbolas, radar velocities were obtained for the 100-MHz ground-based profile. Using the velocities and Paren’s mixture formula, we calculated the water content of the ice to have been in the range of 0.00–0.09. High water content occurs near the glacier margin, in sub-glacial valleys, and in zones of scattering noise.

关键词： GPR water content Fourcade glacier scattering noise migration velocity analysis fractures

A facile synthesis of hierarchical Sn3O4 nanostructures in an acidic aqueous solution and their strong visible- light-driven photocatalytic activity

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Nano Research 2015年第11期8卷 3553-3561页

作者： Hui Song Su-young Son Seul Ki kim Gun young Jung School of Materials Science and Engineering Gwangju Institute of Science and Technology (GIST) Gwangju 500-712 Republic of Korea Carbon Convergence Materials Research Center Institute of Advanced Composite Materials Korea Institute of Science and Technology (KIST) Jeollabuk-do 565-905 Republic of Korea

Hierarchical tin（Ⅲ） oxide, Sn3O4, nanospheres were synthesized via hydrothermal reaction under strongly acidic ambient conditions. The morphology of Sn3O4 varied with decreasing pH. The prickly SnaO4 nanospheres changed into SnaO4 nanospheres covered with single-crystalline nanoplates having a high BET surface area of ca. 55.05 m^2·g^-1 and a band gap of ca. 2.25 eV. Small amounts （0.05 g） of the hierarchical Sn3O4 nanostructures completely decomposed a 30% methyl orange （MO） solution in 100 mL deionized water within 15 min under one sun condition （UV ＋ visible light）. The Sn3O4 photocatalyst exhibited a fast decomposition rate of 1.73 ×10^-1 min^-1, which is a 90.86% enhancement relative to that of the commercially available P25 photocatalyst. The high photocatalytic activity of the hierarchical Sn3O4 nanostructures is attributed to its ability to absorb visible light and its high surface-to-volume ratio.

关键词： Sn3O4 hierarchical structure hydrothermal morphology engineering photocatalyst

Chicken soup for teaching and learning ESD

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World Journal of Gastroenterology 2011年第21期17卷 2618-2622页

作者： Eun young kim Seong Woo Jeon Gwang Ha kim Division of Gastroenterology Department of Internal MedicineCatholic University of Daegu School of Medicine Division of Gastroenterology Department of Internal MedicineKyungpook National University School of Medicine Department of Internal Medicine Pusan National University School of Medicine and Medical Research InstitutePusan National University Hospital

Endoscopic submucosal dissection(ESD) is becoming a popular procedure for the diagnosis and treatment of superficial mucosal lesions,and has the advantage of en bloc resection which yields a higher complete resection and remission rate compared to endoscopic mucosal resection(EMR).However,the learning process of this advanced endoscopic procedure requires a lengthy training period and considerable experience to be proficient.A well framed training protocol which is safe,effective,easily reproducible and cost-effective is desirable to teach *** addition,the training course may need to be tailored around settings such as ethnicity,culture,workload,and disease *** Asian countries with a large volume of early gastric lesions which need endoscopic treatment,endoscopists would be able to learn ESD expanding their skills from EMR to ESD under the supervision of ***,in Western countries due to the low incidence of superficial gastric tumors,trials have utilized simulator models to improve *** Korea,the Korean Society of Gastrointestinal Endoscopy(KSGE) is playing an important role in training many gastroenterologists who have shown an interest in performing ESD by providing an annual live demonstration and a nationwide tutoring *** purpose of this article is to introduce our ESD tutoring experience,review the published papers related to this topic,and propose several suggestions for future directions in teaching and learning ESD.

关键词： Endoscopic submucosal dissection Learning Teaching

Complete peritonectomy and intraperitoneal chemotherapy for recurrent rectal cancer with peritoneal metastasis

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World Journal of Gastroenterology 2009年第6期15卷 756-757页

作者： Jung Wook Huh young Jin kim Hyeong Rok kim Department of Surgery Chonnam National University Hwasun Hospital and Medical SchoolGwangju 501-757South Korea

A 68-year-old man underwent laparoscopic low anterior resection for rectal carcinoma in December *** 19 mo after the operation,he developed recurrent rectal cancer with peritoneal metastasis. In September 2008,he subsequently underwent a laparotomy with a peritonectomy,omentectomy, splenectomy,and a Hartmann *** intraperitoneal oxaliplatin 750 mg was administered. The patient was discharged with no postoperative complications and has been well with postoperative FOLFOX chemotherapy.

关键词： Peritonectomy Peritoneal metastasis Recurrent rectal cancer

Amomum villosum induces longitudinal bone growth in adolescent female rats

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Journal of Traditional Chinese Medicine 2012年第3期32卷 453-458页

作者： Sun Haeng Lee Ji young kim Hocheol kim Seul Ki Park Cho young kim Sun Yong Chung Gyu Tae Chang Department of Pediatrics of Korean Medicine Kyung Hee University Hospital at Gang-dong892 Dongnam-roGangdong-guSeoul 134-727Republic of Korea Department of Herbal Pharmacology College of Korean MedicineKyung Hee University26 Kyungheedae-roDongdaemoon-guSeoul 130-701Republic of Korea Department of Neuropsychiatry of Korean Medicine Kyung Hee University Hospital at Gang-dong892 Dongnam-roGangdong-guSeoul 134727Republic of Korea

OBJECTIVE:This study was conducted to evaluate the effect of Amomum villosum on longitudinal bone ***:Adolescent female Sprague-Dawley rats were divided into 3 groups and treated for 4 days:control(distilled water,p.o.),recombinant human growth hormone(rhGH;100 μg/kg,s.c.),and ***(500 mg/kg,p.o.) *** day 3,tetracycline(20 g/kg,i.p.) was injected for growth plate *** days 2,3 and 4,5-bromo-2'-deoxyuridine(BrdU)(50 mg/kg,i.p.) was injected to label proliferating *** day 5,tibias were dissected and fixed in 4% paraformaldehyde,dehydrated,and sectioned for immunohistochemistry and ***:The rate of bone growth in the *** and rhGH groups increased to(410 ± 44) and(389 ± 46) μm/day(P<0.01),respectively,as compared with the control(330.7 ± 34.7) μm/*** thickness of the growth plates also increased to(591 ± 37) and(598 ± 32) μm,respectively,as compared with the control(524± 89) μm(P<0.001).The number of BrdU-positive cells in the chondrocytes of the *** and rhGH groups was also significantly higher(126±24) and(143±18) cells/mm 2,respectively) than in the control(109 ± 25) mm 2(P<0.05).Insulin-like growth factor-1 and bone morphogenetic protein-2 in the *** and rhGH groups were highly expressed in the growth plate as compared with the control samples,indicating increased bone ***:*** could be used to treat growth retardation during adolescence.

关键词： Amomum villosum Growth plate Bone Development Recombinant human growth hormone

Predicting Concrete Compressive Strength Using Deep Convolutional Neural Network Based on Image Characteristics

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Computers, Materials & Continua 2020年第10期65卷 1-17页

作者： Sanghyo Lee Yonghan Ahn Ha young kim Division of Architecture and Civil Engineering Kangwon National UniversitySamcheok-si25913Korea School of Architecture and Architectural Engineering Hanyang University ERICAAnsan-si15588Korea Graduate School of Information Yonsei UniversitySeoul03722Korea

In this study,we examined the efficacy of a deep convolutional neural network(DCNN)in recognizing concrete surface images and predicting the compressive strength of concrete.A digital single-lens reflex(DSLR)camera and microscope were simultaneously used to obtain concrete surface images used as the input data for the ***,training,validation,and testing of the DCNNs were performed based on the DSLR camera and microscope image *** of the analysis indicated that the DCNN employing DSLR image data achieved a relatively higher *** accuracy of the DSLR-derived image data was attributed to the relatively wider range of the DSLR camera,which was beneficial for extracting a larger number of ***,the DSLR camera procured more realistic images than the ***,when the compressive strength of concrete was evaluated using the DCNN employing a DSLR camera,time and cost were reduced,whereas the usefulness ***,an indirect comparison of the accuracy of the DCNN with that of existing non-destructive methods for evaluating the strength of concrete proved the reliability of DCNN-derived concrete strength *** addition,it was determined that the DCNN used for concrete strength evaluations in this study can be further expanded to detect and evaluate various deteriorative factors that affect the durability of structures,such as salt damage,carbonation,sulfation,corrosion,and freezing-thawing.

关键词： Deep convolutional neural network(DCNN) non-destructive testing(NDT) concrete compressive strength digital single-lens reflex(DSLR)camera microscope

Korean red ginseng promotes hippocampal neurogenesis in mice

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Neural Regeneration Research 2020年第5期15卷 887-893页

作者： Sun Ryu Hyongjun Jeon Hee-young kim Sungtae Koo Seungtae kim Korean Medicine Research Center for Healthy Aging Pusan National University49 Busandaehak-roMulgeum-eupYangsan-siGyeongsangnam-do 50612Republic of Korea Department of Korean Medical Science School of Korean MedicinePusan National University49 Busandaehak-roMulgeum-eupYangsan-siGyeongsangnam-do 50612Republic of Korea

Neurogenesis in the adult hippocampus plays a major role in cognitive ability of animals including learning and *** red ginseng (KRG) has long been known as a medicinal herb with the potential to improve learning and memory;however,the mechanisms are still ***,we evaluated whether KRG can promote cognitive function and enhance neurogenesis in the ***-week-old male C57BL/6 mice received 50 mg/kg of 5-bromo-2′-deoxyuridine (BrdU) intraperitoneally and 100 mg/kg of KRG or vehicle orally once a day for 14 ***,Rotarod and Morris water maze tests were performed and the brains were collected after the last behavioral *** in the numbers of BrdU- and BrdU/ doublecortin (DCX;a marker for neuronal precursor cells and immature neurons)-positive cells in the dentate gyrus and the gene expression of proliferating cell nuclear antigen (a marker for cell differentiation),cerebral dopamine neurotrophic factor and ciliary neurotrophic factor in the hippocampus were then ***-treated mice came down the pole significantly faster and stood on the rotarod longer than vehicle-treated *** Morris water maze test showed that KRG administration enhanced the learning and memory abilities *** also significantly increased BrdU- and BrdU/DCX-positive cells in the dentate gyrus as well as the proliferating cell nuclear antigen,cerebral dopamine neurotrophic factor and ciliary neurotrophic factor mRNA expression levels in the hippocampus compared to *** of KRG promotes learning and memory abilities,possibly by enhancing hippocampal *** study was approved by the Pusan National University Institutional Animal Care and Use Committee (approval ***-2016-1071) on January 19,2016.

关键词： bromodeoxyuridine cerebral dopamine neurotrophic factor ciliary neurotrophic factor doublecortin ginseng hippocampus Korean red ginseng learning memory neurogenesis proliferating cell nuclear antigen red ginseng

Oxyntic gland adenoma endoscopically mimicking a gastric neuroendocrine tumor: A case report

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World Journal of Gastroenterology 2015年第16期21卷 5099-5104页

作者： Tae-In Lee Jae-young Jang Seungmin kim Jung-Wook kim young-Woon Chang Youn-Wha kim Division of Gastroenterology Department of Internal MedicineCollege of MedicineKyung Hee University Department of Pathology College of MedicineKyung Hee University

Gastric adenocarcinoma is one of the most common malignancies *** and immunohistologic analyses classify the phenotypes of gastric adenocarcinoma into several groups based on the variable clinical and pathologic features.A new and rare variant of gastric adenocarcinoma with chief cell differentiation(GA-CCD)has recently been *** reporting the distinct clinicopathologic characteristics proposed the term oxyntic gland polyp/adenoma because of the benign nature of the ***,GA-CCD is a solitary mucosal lesion that develops either in the gastric cardia or ***,this lesion is characterized by tightly clustered glands and anastomosing cords of chief ***,GA-CCD is diffusely positive for mucin(MUC)6 and negative for MUC2and ***,other gastric tumors such as a gastric neuroendocrine tumor or fundic gland polyp have been difficult to *** GA-CCD tends to be endoscopically misdiagnosed as a neuroendocrine tumor or fundic gland polyp,comprehensive assessment and observation by an endoscopist are strongly ***,we report a rare case of oxyntic gland adenoma endoscopically mimicking a gastric neuroendocrine tumor that was successfully removed by endoscopic mucosal resection.

关键词： Chief cell differentiation Gastric carcinoma Mucin 6 Neuroendocrine tumor Oxyntic gland adenoma

Iatrogenic colorectal perforation induced by anorectal manometry:Report of two cases after restorative proctectomy for distal rectal cancer

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World Journal of Gastroenterology 2007年第45期13卷 6112-6114页

作者： Jun-Seok Park Sung-Bum Kang Duck-Woo kim Na-young kim Kyoung-Ho Lee young-Hoon kim Department of Surgery Chung-Ang University Hospital Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 463-707 Korea Department of Surgery Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 463-707 Korea Department of Internal Medicine Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 463-707 Korea Department of Diagnostic Radiology Seoul National University Bundang Hospital

There are no reports regarding perforation of the colorectum induced by anorectal manometry. We report two cases of colorectal perforation that occurred during manometry in the patients undergoing restorative proctectomy for distal rectal cancer. In the first patient, computed tomography showed an extraperitoneal perforation in the pelvic cavity and a rupture of the rectal wall. A localized perforation into the retroperitoneum was managed conservatively. In the second patient, a 3 cm linear colon rupture was detected above the anastomotic site. A primary closure of the perforated colon and proximal ileostomy were conducted, but the patient died 2 wk later. We hypothesize that the perforation induced by anorectal manometry may be associated with the relative weakening of the proximal bowel wall due to anastomosis, decreased compliance, and abnormal rectal sensation. We suggest that measurement of the maximum tolerable volume should not be routinely performed alter restorative proctectomy for distal rectal cancer.

关键词： Iatrogenic perforation Anorectal manometry Rectal cancer Low anterior resection

Clinicopathologic characteristics of gastric carcinoma in elderly patients: A comparison with young patients

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World Journal of Gastroenterology 2005年第1期11卷 22-26页

作者： Dong-Yi kim Jae-Kyoon Joo Seong-Yeob Ryu young-Kyu Park young-Jin kim Shin-Kon kim Division of Gastroenterologic Surgery

AIM:To examine the clinicopathologic features of elderly patients with gastric carcinoma and to investigate the relationship between prognosis and ***: We reviewed the hospital records of 2 014patients with gastric carcinoma retrospectively to compare the clinicopathologic findings in elderly (age ＞70 years) and young (age ＜36 years) patients during the period from 1986 to 2000 in a tertiary referral center in Gwangju, Korea. Overall survival was the main outcome ***: Of the 2 014 patients, 194 (9.6%) were in the elderly group and 137 (6.8%) were in the young *** elderly and young patients had similar distributions with respect to depth of invasion, nodal involvement, hepatic metastasis, peritoneal dissemination, tumor stage at the initial diagnosis, and type of surgery. Synchronous multiple carcinomas were found in 14/194 (7.2%) of the elderly group and 4/137 (2.9%) of the young group (P＜0.05). Using the Borrmann classification, type Ⅳ was more frequent in the young patients than in the elderly patients (P＜0.05).Significantly more elderly patients had a well or moderately differentiated histology, and more young patients had a poorly differentiated histology and signet ring cell carcinoma (P＜0.001). The 5-year survival rates of elderly and young patients did not differ statistically (52.8% vs 46.5%,P = 0.5290). Multivariate analysis showed that the histologic type, nodal involvement and operative curability were significant prognostic factors, and age itself was not an independent prognostic factor of survival for elderly gastric carcinoma ***: Elderly patients with gastric carcinoma do not have a worse prognosis than young patients. The important prognostic factor is whether the patients undergo a curative resection.

关键词： Gastric carcinomas Prognosis Age Surgery